{"id":"https://openalex.org/W2054024422","doi":"https://doi.org/10.1186/1752-0509-3-83","title":"Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network","display_name":"Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network","publication_year":2009,"publication_date":"2009-08-23","ids":{"openalex":"https://openalex.org/W2054024422","doi":"https://doi.org/10.1186/1752-0509-3-83","mag":"2054024422","pmid":"https://pubmed.ncbi.nlm.nih.gov/19698179"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-3-83","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-83","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/1752-0509-3-83","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/1752-0509-3-83","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085743760","display_name":"Clemens K\u00fchn","orcid":"https://orcid.org/0000-0002-9853-5307"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Clemens K\u00fchn","raw_affiliation_strings":["Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany. clemens.kuehn@biologie.hu-berlin.de","Max-Planck-Institute for Molecular Genetics, Berlin, Germany","Humboldt Universit\u00e4t zu Berlin, Institute for Biology, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany. clemens.kuehn@biologie.hu-berlin.de","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Humboldt Universit\u00e4t zu Berlin, Institute for Biology, Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028267040","display_name":"Christoph Wierling","orcid":"https://orcid.org/0000-0002-8856-8412"},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christoph Wierling","raw_affiliation_strings":["Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","Max Planck Institute  for Molecular Genetics, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Max Planck Institute  for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061532112","display_name":"Alexander K\u00fchn","orcid":"https://orcid.org/0000-0002-2748-5242"},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander K\u00fchn","raw_affiliation_strings":["Max Planck Institute  for Molecular Genetics, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max Planck Institute  for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003799374","display_name":"Edda Klipp","orcid":"https://orcid.org/0000-0002-0567-7075"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Edda Klipp","raw_affiliation_strings":["Humboldt Universitt zu Berlin, Institute for Biology, Invalidenstr 42, 10115 Berlin, Germany","Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","Humboldt Universit\u00e4t zu Berlin, Institute for Biology, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Humboldt Universitt zu Berlin, Institute for Biology, Invalidenstr 42, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]},{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Humboldt Universit\u00e4t zu Berlin, Institute for Biology, Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009532945","display_name":"G. V. Panopoulou","orcid":"https://orcid.org/0000-0001-7482-5759"},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Georgia Panopoulou","raw_affiliation_strings":["Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","Max Planck Institute  for Molecular Genetics, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Max Planck Institute  for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019720850","display_name":"Hans Lehrach","orcid":null},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans Lehrach","raw_affiliation_strings":["Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","Max Planck Institute  for Molecular Genetics, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Max Planck Institute  for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007743755","display_name":"Albert J. Poustka","orcid":null},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Albert J Poustka","raw_affiliation_strings":["Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","Max Planck Institute  for Molecular Genetics, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, 14195 Berlin, Germany and","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Max Planck Institute  for Molecular Genetics, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5085743760"],"corresponding_institution_ids":["https://openalex.org/I39343248","https://openalex.org/I4210142260"],"apc_list":null,"apc_paid":{"value":1059,"currency":"EUR","value_usd":1142},"fwci":0.8088,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.71715916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"1","first_page":"83","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ode","display_name":"Ode","score":0.7636641263961792},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5789971351623535},{"id":"https://openalex.org/keywords/bottleneck","display_name":"Bottleneck","score":0.5448054075241089},{"id":"https://openalex.org/keywords/monte-carlo-method","display_name":"Monte Carlo method","score":0.5281296372413635},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.5122730135917664},{"id":"https://openalex.org/keywords/completeness","display_name":"Completeness (order theory)","score":0.4407689571380615},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.4251033663749695},{"id":"https://openalex.org/keywords/estimation-theory","display_name":"Estimation theory","score":0.42009350657463074},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.4053204655647278},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.3450031280517578},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.3336649537086487},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.32882553339004517},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2814220190048218},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.20270448923110962},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1301039457321167},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.12800079584121704}],"concepts":[{"id":"https://openalex.org/C34862557","wikidata":"https://www.wikidata.org/wiki/Q178985","display_name":"Ode","level":2,"score":0.7636641263961792},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5789971351623535},{"id":"https://openalex.org/C2780513914","wikidata":"https://www.wikidata.org/wiki/Q18210350","display_name":"Bottleneck","level":2,"score":0.5448054075241089},{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.5281296372413635},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.5122730135917664},{"id":"https://openalex.org/C17231256","wikidata":"https://www.wikidata.org/wiki/Q5156540","display_name":"Completeness (order theory)","level":2,"score":0.4407689571380615},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.4251033663749695},{"id":"https://openalex.org/C167928553","wikidata":"https://www.wikidata.org/wiki/Q1376021","display_name":"Estimation theory","level":2,"score":0.42009350657463074},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.4053204655647278},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.3450031280517578},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.3336649537086487},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.32882553339004517},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2814220190048218},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.20270448923110962},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1301039457321167},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12800079584121704},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008648","descriptor_name":"Mesoderm","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008648","descriptor_name":"Mesoderm","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008648","descriptor_name":"Mesoderm","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009010","descriptor_name":"Monte Carlo Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009010","descriptor_name":"Monte Carlo Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009010","descriptor_name":"Monte Carlo Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1186/1752-0509-3-83","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-83","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/1752-0509-3-83","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:19698179","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19698179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pure.mpg.de:item_1584103","is_oa":true,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-0010-7D33-3","pdf_url":"http://hdl.handle.net/11858/00-001M-0000-0010-7D33-3","source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_1584103","is_oa":true,"landing_page_url":"https://hdl.handle.net/11858/00-001M-0000-0010-7D33-3","pdf_url":"http://hdl.handle.net/11858/00-001M-0000-0010-7D33-3","source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:edoc.mpg.de:457106","is_oa":true,"landing_page_url":"http://edoc.mpg.de/457106","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, v.3, 83-83 (2009)","raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2739852","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2739852","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-3-83","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-83","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/1752-0509-3-83","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life below water","score":0.8700000047683716,"id":"https://metadata.un.org/sdg/14"}],"awards":[{"id":"https://openalex.org/G4447653093","display_name":null,"funder_award_id":"Network","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2054024422.pdf","grobid_xml":"https://content.openalex.org/works/W2054024422.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W986840029","https://openalex.org/W1579482787","https://openalex.org/W1969487642","https://openalex.org/W1973919812","https://openalex.org/W1995907191","https://openalex.org/W2002088683","https://openalex.org/W2021210659","https://openalex.org/W2032074345","https://openalex.org/W2035949664","https://openalex.org/W2053505129","https://openalex.org/W2054646046","https://openalex.org/W2057195804","https://openalex.org/W2061851611","https://openalex.org/W2062029454","https://openalex.org/W2067241457","https://openalex.org/W2068244389","https://openalex.org/W2086195614","https://openalex.org/W2100262444","https://openalex.org/W2101043145","https://openalex.org/W2104447857","https://openalex.org/W2107062718","https://openalex.org/W2110438893","https://openalex.org/W2120009112","https://openalex.org/W2120889810","https://openalex.org/W2127938895","https://openalex.org/W2131636689","https://openalex.org/W2132997183","https://openalex.org/W2140216162","https://openalex.org/W2142072523","https://openalex.org/W2156800723","https://openalex.org/W2167193572","https://openalex.org/W4238726034","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1657880117","https://openalex.org/W2595172197","https://openalex.org/W2371448224","https://openalex.org/W3134495997","https://openalex.org/W2363680170","https://openalex.org/W2127970246","https://openalex.org/W2376428685","https://openalex.org/W2084856301","https://openalex.org/W1001352512","https://openalex.org/W4382618745"],"abstract_inverted_index":{"The":[0,19,37],"method":[1,23,85],"described":[2],"in":[3,26,44,105],"this":[4,22],"paper":[5],"enables":[6],"an":[7],"evaluation":[8],"of":[9,12,21,31,94,112],"network":[10,46,65],"topologies":[11],"GRNs":[13,103],"without":[14],"requiring":[15],"any":[16,95],"parameter":[17],"values.":[18],"benefit":[20],"is":[24,114],"exemplified":[25],"the":[27,32,45,64,110],"first":[28],"mathematical":[29,68],"analysis":[30],"complete":[33],"Endomesoderm":[34],"Network":[35],"Model.":[36],"predictions":[38],"we":[39],"provide":[40],"deliver":[41],"candidate":[42],"nodes":[43],"that":[47,83],"are":[48,119],"likely":[49],"to":[50,62,89],"be":[51,87,99],"erroneous":[52],"or":[53],"miss":[54],"unknown":[55,115],"connections,":[56],"which":[57],"may":[58],"need":[59],"additional":[60],"experiments":[61],"improve":[63],"topology.":[66],"This":[67,97],"model":[69],"can":[70,86],"serve":[71],"as":[72],"a":[73,91],"scaffold":[74],"for":[75,102],"detailed":[76],"and":[77],"more":[78],"realistic":[79],"models.":[80],"We":[81],"propose":[82],"our":[84],"used":[88],"assess":[90],"completeness":[92],"grade":[93],"GRN.":[96],"could":[98],"especially":[100],"useful":[101],"involved":[104],"human":[106],"diseases,":[107],"where":[108],"often":[109],"amount":[111],"connectivity":[113],"and/or":[116],"many":[117],"genes/interactions":[118],"missing.":[120]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}