{"id":"https://openalex.org/W1968350981","doi":"https://doi.org/10.1186/1752-0509-3-8","title":"Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms","display_name":"Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms","publication_year":2009,"publication_date":"2009-01-15","ids":{"openalex":"https://openalex.org/W1968350981","doi":"https://doi.org/10.1186/1752-0509-3-8","mag":"1968350981","pmid":"https://pubmed.ncbi.nlm.nih.gov/19146695"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-3-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-8","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-8","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073222532","display_name":"Jan Baumbach","orcid":"https://orcid.org/0000-0002-0282-0462"},"institutions":[{"id":"https://openalex.org/I1297971548","display_name":"International Computer Science Institute","ror":"https://ror.org/01ewh7m12","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1297971548"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jan Baumbach","raw_affiliation_strings":["International Computer Science Institute, Berkeley, CA 94704, USA. jbaumbac@icsi.berkeley.edu","International Computer Science Institute Berkeley, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Computer Science Institute, Berkeley, CA 94704, USA. jbaumbac@icsi.berkeley.edu","institution_ids":["https://openalex.org/I1297971548"]},{"raw_affiliation_string":"International Computer Science Institute Berkeley, USA#TAB#","institution_ids":["https://openalex.org/I1297971548"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059606670","display_name":"Sven Rahmann","orcid":"https://orcid.org/0000-0002-8536-6065"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sven Rahmann","raw_affiliation_strings":["Bioinformatics for High-Throughput Technologies, Technical University of Dortmund, Dortmund, D-44227, Germany","Bioinformatics for High-Throughput Technologies, Technical University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics for High-Throughput Technologies, Technical University of Dortmund, Dortmund, D-44227, Germany","institution_ids":["https://openalex.org/I200332995"]},{"raw_affiliation_string":"Bioinformatics for High-Throughput Technologies, Technical University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069682981","display_name":"Andreas Tauch","orcid":null},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andreas Tauch","raw_affiliation_strings":["Institute for Genome Research and Systems Biology, Center for Biotechnology, Bielefeld University, Bielefeld, D-33594, Germany","Institute for Genome Research and Systems Biology, Center for Biotechnology, Bielefeld University, Bielefeld, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Genome Research and Systems Biology, Center for Biotechnology, Bielefeld University, Bielefeld, D-33594, Germany","institution_ids":["https://openalex.org/I20121455"]},{"raw_affiliation_string":"Institute for Genome Research and Systems Biology, Center for Biotechnology, Bielefeld University, Bielefeld, Germany","institution_ids":["https://openalex.org/I20121455"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5073222532"],"corresponding_institution_ids":["https://openalex.org/I1297971548"],"apc_list":null,"apc_paid":null,"fwci":2.2973,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.87624505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"3","issue":"1","first_page":"8","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.25060001015663147,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.25060001015663147,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.13009999692440033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.10949999839067459,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6745587587356567},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6549492478370667},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6498032808303833},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5574239492416382},{"id":"https://openalex.org/keywords/dna-binding-site","display_name":"DNA binding site","score":0.5503782033920288},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5279920101165771},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.49749210476875305},{"id":"https://openalex.org/keywords/organism","display_name":"Organism","score":0.4906824827194214},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.4714658856391907},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"Horizontal gene transfer","score":0.47022151947021484},{"id":"https://openalex.org/keywords/model-organism","display_name":"Model organism","score":0.4551108777523041},{"id":"https://openalex.org/keywords/regulatory-sequence","display_name":"Regulatory sequence","score":0.4493201971054077},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.4291457235813141},{"id":"https://openalex.org/keywords/conserved-sequence","display_name":"Conserved sequence","score":0.41776201128959656},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2725771367549896},{"id":"https://openalex.org/keywords/promoter","display_name":"Promoter","score":0.26967012882232666}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6745587587356567},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6549492478370667},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6498032808303833},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5574239492416382},{"id":"https://openalex.org/C3662595","wikidata":"https://www.wikidata.org/wiki/Q5205743","display_name":"DNA binding site","level":5,"score":0.5503782033920288},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5279920101165771},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.49749210476875305},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.4906824827194214},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.4714658856391907},{"id":"https://openalex.org/C92938381","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Horizontal gene transfer","level":4,"score":0.47022151947021484},{"id":"https://openalex.org/C19843653","wikidata":"https://www.wikidata.org/wiki/Q213907","display_name":"Model organism","level":3,"score":0.4551108777523041},{"id":"https://openalex.org/C21592294","wikidata":"https://www.wikidata.org/wiki/Q3238407","display_name":"Regulatory sequence","level":4,"score":0.4493201971054077},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4291457235813141},{"id":"https://openalex.org/C199216141","wikidata":"https://www.wikidata.org/wiki/Q4995178","display_name":"Conserved sequence","level":4,"score":0.41776201128959656},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2725771367549896},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.26967012882232666},{"id":"https://openalex.org/C3017666073","wikidata":"https://www.wikidata.org/wiki/Q1764062","display_name":"Base sequence","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003352","descriptor_name":"Corynebacterium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003352","descriptor_name":"Corynebacterium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003352","descriptor_name":"Corynebacterium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1752-0509-3-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-8","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-8","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:19146695","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19146695","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pub.librecat.org:1783240","is_oa":true,"landing_page_url":"https://pub.uni-bielefeld.de/record/1783240","pdf_url":null,"source":{"id":"https://openalex.org/S4306401671","display_name":"PUB \u2013 Publications at Bielefeld University (Bielefeld University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I20121455","host_organization_name":"Bielefeld University","host_organization_lineage":["https://openalex.org/I20121455"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Baumbach J, Rahmann S, Tauch A. Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms. <em>BMC Systems Biology</em>. 2009;3(1):8.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2653031","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2653031","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-3-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-8","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-8","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6600000262260437,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320875","display_name":"Deutscher Akademischer Austauschdienst","ror":"https://ror.org/039djdh30"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1968350981.pdf","grobid_xml":"https://content.openalex.org/works/W1968350981.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1485263095","https://openalex.org/W1853093403","https://openalex.org/W1862117967","https://openalex.org/W1967871008","https://openalex.org/W1976260744","https://openalex.org/W1986075313","https://openalex.org/W1986841498","https://openalex.org/W1989080074","https://openalex.org/W2038012561","https://openalex.org/W2085091160","https://openalex.org/W2094006378","https://openalex.org/W2094036688","https://openalex.org/W2096778187","https://openalex.org/W2103311119","https://openalex.org/W2103739920","https://openalex.org/W2105222452","https://openalex.org/W2109344242","https://openalex.org/W2110734043","https://openalex.org/W2119958068","https://openalex.org/W2122359417","https://openalex.org/W2122465922","https://openalex.org/W2127057035","https://openalex.org/W2133335149","https://openalex.org/W2137993400","https://openalex.org/W2141408320","https://openalex.org/W2148675238","https://openalex.org/W2152013768","https://openalex.org/W2155606054","https://openalex.org/W2156425900","https://openalex.org/W2158714788","https://openalex.org/W2165660562","https://openalex.org/W2168801969","https://openalex.org/W4233951753"],"related_works":["https://openalex.org/W1970337814","https://openalex.org/W2133027051","https://openalex.org/W2072226307","https://openalex.org/W2130150170","https://openalex.org/W2162630564","https://openalex.org/W2972782405","https://openalex.org/W2163667623","https://openalex.org/W4367173723","https://openalex.org/W2128504545","https://openalex.org/W1502510273"],"abstract_inverted_index":{"BACKGROUND:":[0],"Transcriptional":[1],"regulation":[2],"of":[3,26,33,83,86,95,111,129,168,208,230,246],"gene":[4,113,141,163,175,231],"activity":[5],"is":[6,38,77,144,171,236],"essential":[7],"for":[8,40,52,206,216],"any":[9,53],"living":[10],"organism.":[11],"Transcription":[12],"factors":[13],"therefore":[14],"recognize":[15],"specific":[16],"binding":[17,90,131,134,157],"sites":[18],"within":[19,93],"the":[20,24,34,74,80,87,96,109,151,155,161,169,178,184,192,209,244],"DNA":[21],"to":[22,50,69,146,183,214],"regulate":[23],"expression":[25],"particular":[27],"target":[28,162],"genes.":[29],"The":[30,166],"genome-scale":[31,228],"reconstruction":[32],"emerging":[35],"regulatory":[36,114,142,232],"networks":[37,64,233],"important":[39],"biotechnology":[41],"and":[42,48,137,159,191],"human":[43,185],"medicine":[44],"but":[45,240],"cost-intensive,":[46],"time-consuming,":[47],"impossible":[49],"perform":[51],"species":[54],"separately.":[55],"By":[56],"using":[57],"bioinformatics":[58,105],"methods":[59,120],"one":[60],"can":[61,122],"partially":[62],"transfer":[63,229],"from":[65,177],"well-studied":[66],"model":[67,179],"organisms":[68,94,200,235],"closely":[70],"related":[71],"species.":[72],"However,":[73],"prediction":[75],"quality":[76],"limited":[78,242],"by":[79,173,243],"low":[81],"level":[82,245],"evolutionary":[84,247],"conservation":[85],"transcription":[88,152,211],"factor":[89],"sites,":[91,132],"even":[92],"same":[97],"genus.":[98],"RESULTS:":[99],"Here":[100],"we":[101,201],"present":[102],"an":[103],"integrated":[104],"workflow":[106],"that":[107,121,226],"assures":[108],"reliability":[110],"transferred":[112],"networks.":[115],"Our":[116,223],"approach":[117,170],"combines":[118],"three":[119,199],"be":[123,147],"applied":[124],"on":[125],"a":[126],"large-scale:":[127],"re-assessment":[128],"annotated":[130],"subsequent":[133],"site":[135],"prediction,":[136],"homology":[138],"detection.":[139],"A":[140],"interaction":[143],"considered":[145],"conserved":[148],"if":[149],"(1)":[150],"factor,":[153],"(2)":[154],"adjusted":[156],"site,":[158],"(3)":[160],"are":[164],"conserved.":[165],"power":[167],"demonstrated":[172],"transferring":[174],"regulations":[176,205],"organism":[180],"Corynebacterium":[181],"glutamicum":[182],"pathogens":[186],"C.":[187,189,195],"diphtheriae,":[188],"jeikeium,":[190],"biotechnologically":[193],"relevant":[194],"efficiens.":[196],"For":[197],"these":[198],"identified":[202],"reliable":[203],"transcriptional":[204],"~40%":[207],"common":[210],"factors,":[212],"compared":[213],"~5%":[215],"which":[217],"knowledge":[218],"was":[219],"available":[220],"before.":[221],"CONCLUSION:":[222],"results":[224],"suggest":[225],"trustworthy":[227],"between":[234],"feasible":[237],"in":[238],"general":[239],"still":[241],"conservation.":[248]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}