{"id":"https://openalex.org/W2054130025","doi":"https://doi.org/10.1186/1752-0509-3-45","title":"miRNA-regulated dynamics in circadian oscillator models","display_name":"miRNA-regulated dynamics in circadian oscillator models","publication_year":2009,"publication_date":"2009-05-05","ids":{"openalex":"https://openalex.org/W2054130025","doi":"https://doi.org/10.1186/1752-0509-3-45","mag":"2054130025","pmid":"https://pubmed.ncbi.nlm.nih.gov/19413912"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-3-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-45","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-45","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-45","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032944944","display_name":"Amitabha Nandi","orcid":"https://orcid.org/0000-0002-6688-0237"},"institutions":[{"id":"https://openalex.org/I152429107","display_name":"Jawaharlal Nehru University","ror":"https://ror.org/0567v8t28","country_code":"IN","type":"education","lineage":["https://openalex.org/I152429107"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amitabha Nandi","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi 110067, India. writeamitabha@gmail.com","Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi 110067, India. writeamitabha@gmail.com","institution_ids":["https://openalex.org/I152429107"]},{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030534184","display_name":"Candida Vaz","orcid":"https://orcid.org/0000-0002-6650-7889"},"institutions":[{"id":"https://openalex.org/I152429107","display_name":"Jawaharlal Nehru University","ror":"https://ror.org/0567v8t28","country_code":"IN","type":"education","lineage":["https://openalex.org/I152429107"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Candida Vaz","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031877851","display_name":"Alok Bhattacharya","orcid":"https://orcid.org/0000-0001-7907-6355"},"institutions":[{"id":"https://openalex.org/I152429107","display_name":"Jawaharlal Nehru University","ror":"https://ror.org/0567v8t28","country_code":"IN","type":"education","lineage":["https://openalex.org/I152429107"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Alok Bhattacharya","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]},{"raw_affiliation_string":"School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058911791","display_name":"Ramakrishna Ramaswamy","orcid":"https://orcid.org/0000-0002-9085-8224"},"institutions":[{"id":"https://openalex.org/I152429107","display_name":"Jawaharlal Nehru University","ror":"https://ror.org/0567v8t28","country_code":"IN","type":"education","lineage":["https://openalex.org/I152429107"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Ramakrishna Ramaswamy","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","School of Physical Sciences, Jawaharlal Nehru University, New Delhi, 110067, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, School of Information Technology, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]},{"raw_affiliation_string":"School of Physical Sciences, Jawaharlal Nehru University, New Delhi, 110067, India","institution_ids":["https://openalex.org/I152429107"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5058911791"],"corresponding_institution_ids":["https://openalex.org/I152429107"],"apc_list":null,"apc_paid":null,"fwci":1.9769,"has_fulltext":true,"cited_by_count":44,"citation_normalized_percentile":{"value":0.84045584,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"1","first_page":"45","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.427700012922287,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.427700012922287,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.13249999284744263,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.06400000303983688,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.777982234954834},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.652996838092804},{"id":"https://openalex.org/keywords/translation","display_name":"Translation (biology)","score":0.6447587013244629},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.623885452747345},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.6125195026397705},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5353472828865051},{"id":"https://openalex.org/keywords/negative-feedback","display_name":"Negative feedback","score":0.4725479781627655},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4683263599872589},{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.4656340181827545},{"id":"https://openalex.org/keywords/oscillation","display_name":"Oscillation (cell signaling)","score":0.44629982113838196},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"Gene silencing","score":0.4399266242980957},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.43024295568466187},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.41670626401901245},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.333121120929718},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.28991562128067017},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10692363977432251}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.777982234954834},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.652996838092804},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.6447587013244629},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.623885452747345},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.6125195026397705},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5353472828865051},{"id":"https://openalex.org/C93586867","wikidata":"https://www.wikidata.org/wiki/Q62527","display_name":"Negative feedback","level":3,"score":0.4725479781627655},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4683263599872589},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.4656340181827545},{"id":"https://openalex.org/C2778439541","wikidata":"https://www.wikidata.org/wiki/Q7106412","display_name":"Oscillation (cell signaling)","level":2,"score":0.44629982113838196},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.4399266242980957},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43024295568466187},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.41670626401901245},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.333121120929718},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.28991562128067017},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10692363977432251},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034743","descriptor_name":"RNA-Induced Silencing Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034743","descriptor_name":"RNA-Induced Silencing Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034743","descriptor_name":"RNA-Induced Silencing Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042541","descriptor_name":"Intracellular Space","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042541","descriptor_name":"Intracellular Space","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042541","descriptor_name":"Intracellular Space","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1752-0509-3-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-45","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-45","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:19413912","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19413912","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:europepmc.org:1443338","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2685780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2685780","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2685780","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-3-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-45","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-45","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2054130025.pdf","grobid_xml":"https://content.openalex.org/works/W2054130025.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1575619134","https://openalex.org/W1920303762","https://openalex.org/W1958284284","https://openalex.org/W1966985603","https://openalex.org/W1979385177","https://openalex.org/W1981809365","https://openalex.org/W1986706724","https://openalex.org/W2002995168","https://openalex.org/W2014946489","https://openalex.org/W2027704011","https://openalex.org/W2039245762","https://openalex.org/W2056355047","https://openalex.org/W2066440682","https://openalex.org/W2068274700","https://openalex.org/W2070268185","https://openalex.org/W2072155079","https://openalex.org/W2082496958","https://openalex.org/W2084781111","https://openalex.org/W2089001345","https://openalex.org/W2108493072","https://openalex.org/W2138664009","https://openalex.org/W2141856214","https://openalex.org/W2151046665","https://openalex.org/W2155418451","https://openalex.org/W2157741650","https://openalex.org/W2170762281","https://openalex.org/W2292621739"],"related_works":["https://openalex.org/W2979508935","https://openalex.org/W2107064980","https://openalex.org/W2952117239","https://openalex.org/W2270468432","https://openalex.org/W819328480","https://openalex.org/W2163149544","https://openalex.org/W3143562902","https://openalex.org/W2171008594","https://openalex.org/W2411136628","https://openalex.org/W2981027764"],"abstract_inverted_index":{"BACKGROUND:":[0],"We":[1,118,156,240],"have":[2,119,196],"studied":[3,120,150],"the":[4,33,38,57,63,74,98,147,165,168,174,177,181,188,201,214,232,254],"dynamics":[5,99,148,189,202],"of":[6,12,19,40,55,65,68,73,86,100,131,136,167,171,179,183,190,203,209,216,226,235,250],"miRNA":[7],"regulation":[8,101,130,135],"in":[9,97,109,159,164,173],"two":[10],"models":[11,145,175],"circadian":[13],"oscillators.":[14],"miRNAs":[15,78,140,172,194],"are":[16,26,79,245],"a":[17,66,83,162,197,248],"class":[18],"small":[20],"RNA":[21],"molecules":[22],"(18-24":[23],"nucleotides)":[24],"that":[25,158,242],"known":[27,80],"to":[28,62,81,161],"regulate":[29,82],"gene":[30,115,132,137,217,236],"expression":[31,138],"at":[32],"post-transcriptional":[34],"level":[35,215],"by":[36,43,49,53,71,139,207,212,222,229],"reducing":[37],"amount":[39],"proteins":[41],"produced":[42],"translation.":[44],"This":[45],"is":[46,102,141,149],"done":[47],"either":[48],"blocking":[50],"translation":[51],"or":[52,224,238],"degradation":[54],"mRNAs,":[56],"latter":[58],"being":[59],"mainly":[60],"due":[61],"initiation":[64],"set":[67],"processes":[69,89],"induced":[70],"formation":[72],"miRNA:mRNA":[75],"complex.":[76],"Although":[77],"large":[84],"number":[85],"fundamental":[87],"biological":[88,122],"such":[90],"as":[91,219,221],"growth":[92],"and":[93,146,185],"development,":[94],"their":[95],"role":[96],"not":[103],"completely":[104],"understood.":[105],"In":[106],"exceptional":[107],"cases,":[108],"particular,":[110],"they":[111],"can":[112,195],"also":[113],"up-regulate":[114],"expression.":[116,133],"RESULTS:":[117],"simple":[121],"systems":[123],"wherein":[124],"oscillations":[125],"originate":[126],"from":[127],"negative":[128],"auto":[129],"The":[134],"introduced":[142],"into":[143],"these":[144],"via":[151],"standard":[152],"stochastic":[153],"simulation":[154],"techniques.":[155],"find":[157],"addition":[160],"reduction":[163],"amplitude":[166],"oscillation,":[169],"inclusion":[170],"has":[176],"effect":[178,199],"altering":[180],"frequency":[182],"oscillation":[184],"thereby":[186],"regulating":[187],"protein":[191],"production.":[192],"CONCLUSION:":[193],"profound":[198],"on":[200],"regulatory":[204,251],"modules,":[205],"both":[206],"control":[208,223],"amplitude,":[210],"namely":[211,228],"affecting":[213],"expression,":[218],"well":[220],"alteration":[225],"frequency,":[227],"interference":[230],"with":[231],"temporal":[233],"sequence":[234],"production":[237],"delivery.":[239],"believe":[241],"our":[243],"results":[244],"valid":[246],"for":[247],"variety":[249],"systems,":[252],"beyond":[253],"exemplars":[255],"discussed":[256],"here.":[257]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}