{"id":"https://openalex.org/W1973268559","doi":"https://doi.org/10.1186/1752-0509-3-110","title":"Inferring a transcriptional regulatory network of the cytokinesis-related genes by network component analysis","display_name":"Inferring a transcriptional regulatory network of the cytokinesis-related genes by network component analysis","publication_year":2009,"publication_date":"2009-11-27","ids":{"openalex":"https://openalex.org/W1973268559","doi":"https://doi.org/10.1186/1752-0509-3-110","mag":"1973268559","pmid":"https://pubmed.ncbi.nlm.nih.gov/19943917"},"language":"en","primary_location":{"id":"doi:10.1186/1752-0509-3-110","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-110","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-110","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-110","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111541886","display_name":"Shun-Fu Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I148099254","display_name":"National Chung Cheng University","ror":"https://ror.org/0028v3876","country_code":"TW","type":"education","lineage":["https://openalex.org/I148099254"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Shun-Fu Chen","raw_affiliation_strings":["Department of Chemical Engineering, National Chung Cheng University, Chia-Yi 62102, Taiwan. n810011@yahoo.com.tw","Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-Yi 62102, Taiwan. n810011@yahoo.com.tw","institution_ids":["https://openalex.org/I148099254"]},{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan","institution_ids":["https://openalex.org/I148099254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051006396","display_name":"Yue-Li Juang","orcid":null},"institutions":[{"id":"https://openalex.org/I189772984","display_name":"Tzu Chi University","ror":"https://ror.org/04ss1bw11","country_code":"TW","type":"education","lineage":["https://openalex.org/I189772984"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yue-Li Juang","raw_affiliation_strings":["Department of Microbiology, Tzu-Chi University, Hualien, 970, Taiwan","Department of Microbiology, Tzu-Chi University, Hualien, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tzu-Chi University, Hualien, 970, Taiwan","institution_ids":["https://openalex.org/I189772984"]},{"raw_affiliation_string":"Department of Microbiology, Tzu-Chi University, Hualien, Taiwan","institution_ids":["https://openalex.org/I189772984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047240549","display_name":"Wei-Kang Chou","orcid":null},"institutions":[{"id":"https://openalex.org/I148099254","display_name":"National Chung Cheng University","ror":"https://ror.org/0028v3876","country_code":"TW","type":"education","lineage":["https://openalex.org/I148099254"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wei-Kang Chou","raw_affiliation_strings":["Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, 62102, Taiwan","Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, 62102, Taiwan","institution_ids":["https://openalex.org/I148099254"]},{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan","institution_ids":["https://openalex.org/I148099254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062973903","display_name":"Jin-Mei Lai","orcid":"https://orcid.org/0000-0003-4893-3101"},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jin-Mei Lai","raw_affiliation_strings":["Department of Life Science, Fu-Jen Catholic University, Taipei, Hsien, 242, Taiwan","Department of Life Science, Fu-Jen Catholic University, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, Fu-Jen Catholic University, Taipei, Hsien, 242, Taiwan","institution_ids":["https://openalex.org/I114150738"]},{"raw_affiliation_string":"Department of Life Science, Fu-Jen Catholic University, Taipei, Taiwan","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005204397","display_name":"Chi\u2010Ying F. Huang","orcid":"https://orcid.org/0000-0003-4898-4937"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I4210087697","display_name":"National Yang Ming University Hospital","ror":"https://ror.org/003xdw211","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210087697"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Ying F Huang","raw_affiliation_strings":["Institute of Clinical Medicine, National Yang-Ming University, Taipei, 112, Taiwan","Institute of Clinical Medicine; National Yang Ming University; Taipei Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Clinical Medicine, National Yang-Ming University, Taipei, 112, Taiwan","institution_ids":["https://openalex.org/I4210087697","https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Clinical Medicine; National Yang Ming University; Taipei Taiwan","institution_ids":["https://openalex.org/I4210087697","https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103417824","display_name":"Cheng-Yan Kao","orcid":null},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Cheng-Yan Kao","raw_affiliation_strings":["Department of Computer Science and Information Engineering, National Taiwan University, Taipei, 10617, Taiwan","[dept. of Computer Science and Information Engineering, National Taiwan University, Taipei, Taiwan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Information Engineering, National Taiwan University, Taipei, 10617, Taiwan","institution_ids":["https://openalex.org/I16733864"]},{"raw_affiliation_string":"[dept. of Computer Science and Information Engineering, National Taiwan University, Taipei, Taiwan]","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051642293","display_name":"Feng\u2010Sheng Wang","orcid":"https://orcid.org/0000-0001-5266-2346"},"institutions":[{"id":"https://openalex.org/I148099254","display_name":"National Chung Cheng University","ror":"https://ror.org/0028v3876","country_code":"TW","type":"education","lineage":["https://openalex.org/I148099254"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Feng-Sheng Wang","raw_affiliation_strings":["Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, 62102, Taiwan","Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, 62102, Taiwan","institution_ids":["https://openalex.org/I148099254"]},{"raw_affiliation_string":"Department of Chemical Engineering, National Chung Cheng University, Chia-yi, Taiwan","institution_ids":["https://openalex.org/I148099254"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5111541886"],"corresponding_institution_ids":["https://openalex.org/I148099254"],"apc_list":null,"apc_paid":null,"fwci":0.5415,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.65324565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"3","issue":"1","first_page":"110","last_page":"110"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.5575000047683716,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.5575000047683716,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.2198999971151352,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.13770000636577606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.7801769375801086},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.7142248749732971},{"id":"https://openalex.org/keywords/component","display_name":"Component (thermodynamics)","score":0.6418843865394592},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6227297782897949},{"id":"https://openalex.org/keywords/cytokinesis","display_name":"Cytokinesis","score":0.5957362651824951},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5290999412536621},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5218861699104309},{"id":"https://openalex.org/keywords/network-analysis","display_name":"Network analysis","score":0.4896588921546936},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.4698590040206909},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.4568532109260559},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3877333402633667},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3669082522392273},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.28178104758262634},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.13850528001785278},{"id":"https://openalex.org/keywords/cell-division","display_name":"Cell division","score":0.11449241638183594},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08481955528259277}],"concepts":[{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.7801769375801086},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.7142248749732971},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.6418843865394592},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6227297782897949},{"id":"https://openalex.org/C45472230","wikidata":"https://www.wikidata.org/wiki/Q1447198","display_name":"Cytokinesis","level":4,"score":0.5957362651824951},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5290999412536621},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5218861699104309},{"id":"https://openalex.org/C32946077","wikidata":"https://www.wikidata.org/wiki/Q618079","display_name":"Network analysis","level":2,"score":0.4896588921546936},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.4698590040206909},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4568532109260559},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3877333402633667},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3669082522392273},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.28178104758262634},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.13850528001785278},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.11449241638183594},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08481955528259277},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048749","descriptor_name":"Cytokinesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D048749","descriptor_name":"Cytokinesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D048749","descriptor_name":"Cytokinesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1186/1752-0509-3-110","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-110","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-110","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:19943917","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19943917","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2800846","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2800846","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1752-0509-3-110","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1752-0509-3-110","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/1752-0509-3-110","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2602494990","display_name":null,"funder_award_id":"NSC97-2627-B-002-005","funder_id":"https://openalex.org/F4320321040","funder_display_name":"National Science Council"}],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1973268559.pdf","grobid_xml":"https://content.openalex.org/works/W1973268559.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W1482637285","https://openalex.org/W1502319840","https://openalex.org/W1535241806","https://openalex.org/W1645522610","https://openalex.org/W1906895440","https://openalex.org/W1970249028","https://openalex.org/W1971470015","https://openalex.org/W1973194400","https://openalex.org/W1978577044","https://openalex.org/W1990565440","https://openalex.org/W1992975217","https://openalex.org/W1999259744","https://openalex.org/W2010490271","https://openalex.org/W2014575814","https://openalex.org/W2020758057","https://openalex.org/W2030086669","https://openalex.org/W2045802318","https://openalex.org/W2047663329","https://openalex.org/W2048400182","https://openalex.org/W2068000365","https://openalex.org/W2069645361","https://openalex.org/W2075176255","https://openalex.org/W2076375071","https://openalex.org/W2078631770","https://openalex.org/W2080386975","https://openalex.org/W2080498142","https://openalex.org/W2085308794","https://openalex.org/W2088266134","https://openalex.org/W2088343152","https://openalex.org/W2091060631","https://openalex.org/W2096863518","https://openalex.org/W2103014023","https://openalex.org/W2103453943","https://openalex.org/W2105282404","https://openalex.org/W2112821758","https://openalex.org/W2115445956","https://openalex.org/W2122842475","https://openalex.org/W2126602684","https://openalex.org/W2127303707","https://openalex.org/W2127551419","https://openalex.org/W2127678330","https://openalex.org/W2128683837","https://openalex.org/W2134081084","https://openalex.org/W2142460132","https://openalex.org/W2150819706","https://openalex.org/W2152664017","https://openalex.org/W2156809804","https://openalex.org/W2162503833","https://openalex.org/W2168966628","https://openalex.org/W2170567460"],"related_works":["https://openalex.org/W2158714033","https://openalex.org/W78967844","https://openalex.org/W2949927938","https://openalex.org/W3213185671","https://openalex.org/W4210989272","https://openalex.org/W4206945140","https://openalex.org/W4386628104","https://openalex.org/W2029387041","https://openalex.org/W2130939068","https://openalex.org/W3163717165"],"abstract_inverted_index":{"BACKGROUND:":[0],"Network":[1],"Component":[2],"Analysis":[3],"(NCA)":[4],"is":[5],"a":[6,55,109,217,242,349],"network":[7],"structure-driven":[8],"framework":[9],"for":[10,104,148,201,270,281,340],"deducing":[11],"regulatory":[12,39,62,89,193,252],"signal":[13],"dynamics.":[14],"In":[15,235],"contrast":[16],"to":[17,25,41,60,76,87,159,198,221,249,292,348],"principal":[18],"component":[19],"analysis,":[20],"which":[21,107,215],"can":[22,312,346],"be":[23],"employed":[24],"select":[26],"the":[27,34,49,120,128,131,155,161,177,180,185,191,202,207,225,293,300,307,316,343,356,360],"high-variance":[28],"genes,":[29,66,106],"NCA":[30,84,124,149,173,245,339],"makes":[31],"use":[32],"of":[33,44,64,91,111,127,130,168,176,179,224,254,275,315,370],"connectivity":[35,102,268],"structure":[36],"from":[37,80,95,139,184,258,338],"transcriptional":[38],"networks":[40],"infer":[42,88,250],"dynamics":[43,167],"transcription":[45,92,100,156,169,218,255,266,309,357,364],"factor":[46,93,157,170,219,256,310,365],"activities.":[47],"Using":[48],"budding":[50,208,344,361],"yeast":[51,345,362],"Saccharomyces":[52],"cerevisiae":[53,240],"as":[54,241,359],"model":[56,243],"system,":[57,244],"we":[58],"aim":[59],"deduce":[61],"actions":[63,90,194,253],"cytokinesis-related":[65,105,143,187,204,272,284,317],"using":[67,238],"precise":[68],"spatial":[69],"proximity":[70],"(midbody)":[71],"and/or":[72],"temporal":[73],"synchronicity":[74],"(cytokinesis)":[75],"avoid":[77,136],"full-scale":[78,137],"computation":[79,138],"genome-wide":[81,112,140],"databases.":[82],"RESULTS:":[83],"was":[85,246],"applied":[86,248],"activity":[94,171],"microarray":[96,261],"data":[97,181,276],"and":[98,213,232,263,289,322,327,334],"partial":[99,265],"factor-gene":[101,267],"information":[103],"were":[108,146,174,195],"subset":[110],"datasets.":[113],"No":[114],"literature":[115],"has":[116],"so":[117],"far":[118],"discussed":[119],"inferred":[121,166,192],"results":[122,336],"through":[123,172],"are":[125,329],"independent":[126,175,274],"scale":[129,178],"gene":[132,144,188],"expression":[133,223,314],"dataset.":[134],"To":[135],"databases,":[141],"four":[142,186,282],"cases":[145],"selected":[147,183,203,271,283],"by":[150],"running":[151],"computational":[152],"analysis":[153],"over":[154],"database":[158],"confirm":[160],"approach":[162],"being":[163],"scale-free.":[164],"The":[165,278],"matrix":[182],"sets.":[189],"Moreover,":[190],"nearly":[196],"identical":[197],"published":[199],"observations":[200,302],"genes":[205,273,285,318],"in":[206,304,342,367],"yeast;":[209],"namely,":[210],"Mcm1,":[211],"Ndd1,":[212],"Fkh2,":[214],"form":[216],"complex":[220,311,366],"control":[222],"CLB2":[226],"cluster":[227],"(i.e.":[228],"BUD4,":[229,319],"CHS2,":[230,287,320],"IQG1,":[231,288,321],"CDC5).":[233],"CONCLUSION:":[234],"this":[236],"study,":[237],"S.":[239,305],"successfully":[247],"similar":[251],"activities":[257],"two":[259],"various":[260],"databases":[262],"several":[264],"datasets":[269],"sizes.":[277],"regulated":[279],"action":[280],"(BUD4,":[286],"CDC5)":[290],"belongs":[291],"M-phase":[294],"or":[295],"M/G1":[296],"phase,":[297],"consistent":[298],"with":[299],"empirical":[301],"that":[303,351],"cerevisiae,":[306],"Mcm1-Ndd1-Fkh2":[308,363],"regulate":[313],"CDC5.":[323],"Since":[324],"Bud4,":[325],"Iqg1,":[326],"Cdc5":[328],"highly":[330],"conserved":[331],"between":[332],"human":[333,352],"yeast,":[335],"obtained":[337],"cytokinesis":[341],"lead":[347],"suggestion":[350],"cells":[353],"should":[354],"have":[355],"regulator(s)":[358],"controlling":[368],"occurrence":[369],"cytokinesis.":[371]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-05-03T08:25:01.440150","created_date":"2025-10-10T00:00:00"}