{"id":"https://openalex.org/W2085657320","doi":"https://doi.org/10.1186/1472-6947-14-75","title":"Prediction of adverse cardiac events in emergency department patients with chest pain using machine learning for variable selection","display_name":"Prediction of adverse cardiac events in emergency department patients with chest pain using machine learning for variable selection","publication_year":2014,"publication_date":"2014-08-23","ids":{"openalex":"https://openalex.org/W2085657320","doi":"https://doi.org/10.1186/1472-6947-14-75","mag":"2085657320","pmid":"https://pubmed.ncbi.nlm.nih.gov/25150702"},"language":"en","primary_location":{"id":"doi:10.1186/1472-6947-14-75","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-14-75","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-14-75","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-14-75","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100367554","display_name":"Nan Liu","orcid":"https://orcid.org/0000-0003-3610-4883"},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Nan Liu","raw_affiliation_strings":["Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","institution_ids":["https://openalex.org/I2251586001"]},{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059452714","display_name":"Zhi Xiong Koh","orcid":"https://orcid.org/0000-0001-6440-1709"},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zhi Xiong Koh","raw_affiliation_strings":["Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","institution_ids":["https://openalex.org/I2251586001"]},{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041244916","display_name":"Ken Junyang Goh","orcid":"https://orcid.org/0000-0002-5243-5167"},"institutions":[{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Junyang Goh","raw_affiliation_strings":["Changi General Hospital, Singapore, 529889, Singapore","Changi General Hospital Singapore Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changi General Hospital, Singapore, 529889, Singapore","institution_ids":["https://openalex.org/I2802225915"]},{"raw_affiliation_string":"Changi General Hospital Singapore Singapore","institution_ids":["https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049506273","display_name":"Zhiping Lin","orcid":"https://orcid.org/0000-0002-1587-1226"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zhiping Lin","raw_affiliation_strings":["School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, 639798, Singapore","[School of Electrical and Electronic Engineering, Nanyang Technological University Singapore, Singapore]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, 639798, Singapore","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"[School of Electrical and Electronic Engineering, Nanyang Technological University Singapore, Singapore]","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050519796","display_name":"Benjamin Haaland","orcid":"https://orcid.org/0000-0002-6270-6303"},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Benjamin Haaland","raw_affiliation_strings":["Duke-NUS Graduate Medical School, Singapore, 169857, Singapore","Duke-NUS Graduate Medical School Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke-NUS Graduate Medical School, Singapore, 169857, Singapore","institution_ids":["https://openalex.org/I4210126319"]},{"raw_affiliation_string":"Duke-NUS Graduate Medical School Singapore, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111863644","display_name":"Boon Ping Ting","orcid":null},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Boon Ping Ting","raw_affiliation_strings":["Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore","institution_ids":["https://openalex.org/I2251586001"]},{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087685316","display_name":"Marcus Eng Hock Ong","orcid":"https://orcid.org/0000-0001-7874-7612"},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Marcus Eng Hock Ong","raw_affiliation_strings":["Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore 169608, Singapore. marcus.ong.e.h@sgh.com.sg","Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore 169608, Singapore. marcus.ong.e.h@sgh.com.sg","institution_ids":["https://openalex.org/I2251586001"]},{"raw_affiliation_string":"Department of Emergency Medicine, Singapore General Hospital, Singapore, SINGAPORE","institution_ids":["https://openalex.org/I2251586001"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5087685316"],"corresponding_institution_ids":["https://openalex.org/I2251586001"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":1.2197,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.78908872,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"14","issue":"1","first_page":"75","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.607699990272522,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.607699990272522,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.08969999849796295,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.060499999672174454,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mace","display_name":"Mace","score":0.8308080434799194},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.786990761756897},{"id":"https://openalex.org/keywords/emergency-department","display_name":"Emergency department","score":0.7782262563705444},{"id":"https://openalex.org/keywords/chest-pain","display_name":"Chest pain","score":0.6947370767593384},{"id":"https://openalex.org/keywords/triage","display_name":"Triage","score":0.5796039700508118},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.5499489307403564},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.5481125712394714},{"id":"https://openalex.org/keywords/vital-signs","display_name":"Vital signs","score":0.5267930626869202},{"id":"https://openalex.org/keywords/emergency-medicine","display_name":"Emergency medicine","score":0.47658631205558777},{"id":"https://openalex.org/keywords/adverse-effect","display_name":"Adverse effect","score":0.4288226366043091},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.39423877000808716},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.1830325424671173},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"Myocardial infarction","score":0.1441255509853363},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"Percutaneous coronary intervention","score":0.12735408544540405}],"concepts":[{"id":"https://openalex.org/C2780739214","wikidata":"https://www.wikidata.org/wiki/Q6723023","display_name":"Mace","level":4,"score":0.8308080434799194},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.786990761756897},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.7782262563705444},{"id":"https://openalex.org/C2778704086","wikidata":"https://www.wikidata.org/wiki/Q693058","display_name":"Chest pain","level":2,"score":0.6947370767593384},{"id":"https://openalex.org/C2777120189","wikidata":"https://www.wikidata.org/wiki/Q780067","display_name":"Triage","level":2,"score":0.5796039700508118},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5499489307403564},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5481125712394714},{"id":"https://openalex.org/C2776890885","wikidata":"https://www.wikidata.org/wiki/Q1067560","display_name":"Vital signs","level":2,"score":0.5267930626869202},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.47658631205558777},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4288226366043091},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39423877000808716},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.1830325424671173},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.1441255509853363},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.12735408544540405},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002637","descriptor_name":"Chest Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014218","descriptor_name":"Triage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014218","descriptor_name":"Triage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014218","descriptor_name":"Triage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/1472-6947-14-75","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-14-75","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-14-75","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:25150702","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25150702","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/181489","is_oa":true,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/181489","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Unpaywall 20201031","raw_type":"Article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/102512","is_oa":true,"landing_page_url":"http://hdl.handle.net/10220/24264","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4150554","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4150554","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1472-6947-14-75","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-14-75","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-14-75","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.49000000953674316}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320761","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2085657320.pdf","grobid_xml":"https://content.openalex.org/works/W2085657320.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1568370682","https://openalex.org/W1831050183","https://openalex.org/W1968989582","https://openalex.org/W1979279626","https://openalex.org/W1987045148","https://openalex.org/W2006617902","https://openalex.org/W2008643227","https://openalex.org/W2016107975","https://openalex.org/W2027775877","https://openalex.org/W2034690624","https://openalex.org/W2035519154","https://openalex.org/W2048238199","https://openalex.org/W2057123844","https://openalex.org/W2059137883","https://openalex.org/W2079519845","https://openalex.org/W2095804411","https://openalex.org/W2102831150","https://openalex.org/W2111939820","https://openalex.org/W2118978333","https://openalex.org/W2129374946","https://openalex.org/W2133589238","https://openalex.org/W2139212933","https://openalex.org/W2140190241","https://openalex.org/W2143053797","https://openalex.org/W2143517695","https://openalex.org/W2155116952","https://openalex.org/W2155261478","https://openalex.org/W2157184686","https://openalex.org/W2158698691","https://openalex.org/W2163739552","https://openalex.org/W2168692593","https://openalex.org/W2169167455","https://openalex.org/W2285072859","https://openalex.org/W2317276134","https://openalex.org/W2333727219","https://openalex.org/W2611749980","https://openalex.org/W2911964244","https://openalex.org/W3150728116","https://openalex.org/W4205805944","https://openalex.org/W4241440419","https://openalex.org/W4298441315"],"related_works":["https://openalex.org/W2549128234","https://openalex.org/W1983600708","https://openalex.org/W1986308281","https://openalex.org/W4283694021","https://openalex.org/W2164384113","https://openalex.org/W2569176370","https://openalex.org/W2999305359","https://openalex.org/W2582586980","https://openalex.org/W2585022846","https://openalex.org/W2397971915"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,80,104,220],"key":[2],"aim":[3,33],"of":[4,17,43,59,69,88,100,110,121,186,234,240,245,249,263,269,274,278,295,312],"triage":[5],"in":[6,73,77,282,314,339],"chest":[7,61,102],"pain":[8,62],"patients":[9,63,82],"is":[10,302],"to":[11,34,93,146,159,175,182],"identify":[12],"those":[13],"with":[14,96,223,255],"high":[15],"risk":[16,41,178],"adverse":[18,45],"cardiac":[19,46,116],"events":[20,47],"as":[21,113,133,347],"they":[22],"require":[23],"intensive":[24],"monitoring":[25],"and":[26,52,90,115,136,140,214,236,247,265,276,286,297,344],"early":[27,289],"intervention.":[28],"In":[29],"this":[30,78],"study,":[31],"we":[32],"discover":[35],"the":[36,65,94,124,161,192,197,210,215,231,252,257,287,309],"most":[37,162,199],"relevant":[38,163,200,343],"variables":[39,201,226,259,313],"for":[40,202],"prediction":[42,330],"major":[44],"(MACE)":[48],"using":[49],"clinical":[50,130],"signs":[51,131],"heart":[53,148,218],"rate":[54,149],"variability.":[55],"METHODS:":[56],"A":[57,152,165],"total":[58],"702":[60,187],"at":[64,84,123],"Emergency":[66],"Department":[67],"(ED)":[68],"a":[70,97,108,141,177,237,243,266,272,305,341],"tertiary":[71],"hospital":[72],"Singapore":[74],"were":[75,83,138,206],"included":[76],"study.":[79],"recruited":[81],"least":[85],"30":[86],"years":[87],"age":[89],"who":[91],"presented":[92],"ED":[95],"primary":[98,105,193],"complaint":[99],"non-traumatic":[101],"pain.":[103],"outcome":[106],"was":[107,144,157,172],"composite":[109],"MACE":[111,316],"such":[112,132],"death":[114],"arrest":[117],"within":[118,317],"72":[119,318],"h":[120],"arrival":[122],"ED.":[125],"For":[126],"each":[127],"patient,":[128],"eight":[129],"blood":[134,208],"pressure":[135],"temperature":[137],"measured,":[139],"5-min":[142],"ECG":[143],"recorded":[145],"derive":[147,176],"variability":[150],"parameters.":[151],"random":[153],"forest-based":[154],"novel":[155],"method":[156],"developed":[158],"select":[160],"variables.":[164],"geometric":[166],"distance-based":[167],"machine":[168,333],"learning":[169],"scoring":[170,221,253],"system":[171,222,254],"then":[173],"implemented":[174],"score":[179,239,268,285,291],"from":[180],"0":[181],"100.":[183],"RESULTS:":[184],"Out":[185],"patients,":[188],"29":[189],"(4.1%)":[190],"met":[191],"outcome.":[194],"We":[195,320],"selected":[196],"3":[198,225],"predicting":[203,315],"MACE,":[204],"which":[205],"systolic":[207],"pressure,":[209],"mean":[211,216],"RR":[212],"interval":[213],"instantaneous":[217],"rate.":[219],"these":[224],"produced":[227],"an":[228,261],"area":[229],"under":[230],"curve":[232],"(AUC)":[233],"0.812,":[235],"cutoff":[238,267],"43":[241],"gave":[242,271],"sensitivity":[244,273],"82.8%":[246],"specificity":[248,277],"63.4%,":[250],"while":[251],"all":[256],"23":[258],"had":[260],"AUC":[262,293],"0.736,":[264],"49":[270],"72.4%":[275],"63.0%.":[279],"Conventional":[280],"thrombolysis":[281],"myocardial":[283],"infarction":[284],"modified":[288],"warning":[290],"achieved":[292],"values":[294],"0.637":[296],"0.622,":[298],"respectively.":[299],"CONCLUSIONS:":[300],"It":[301],"observed":[303],"that":[304,322],"few":[306,342],"predictors":[307,324],"outperformed":[308],"whole":[310],"set":[311],"h.":[319],"conclude":[321],"more":[323],"do":[325],"not":[326],"necessarily":[327],"guarantee":[328],"better":[329],"results.":[331],"Furthermore,":[332],"learning-based":[334],"variable":[335],"selection":[336],"seems":[337],"promising":[338],"discovering":[340],"significant":[345],"measures":[346],"predictors.":[348]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}