{"id":"https://openalex.org/W2101194067","doi":"https://doi.org/10.1186/1472-6947-13-s1-s4","title":"Rule-based multi-scale simulation for drug effect pathway analysis","display_name":"Rule-based multi-scale simulation for drug effect pathway analysis","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2101194067","doi":"https://doi.org/10.1186/1472-6947-13-s1-s4","mag":"2101194067","pmid":"https://pubmed.ncbi.nlm.nih.gov/23566173"},"language":"en","primary_location":{"id":"doi:10.1186/1472-6947-13-s1-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-13-s1-s4","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-13-S1-S4","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-13-S1-S4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033201097","display_name":"Woochang Hwang","orcid":"https://orcid.org/0000-0003-0876-7305"},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]},{"id":"https://openalex.org/I4210101891","display_name":"Korea Institute of Brain Science","ror":"https://ror.org/017stnw60","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210101891"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Woochang Hwang","raw_affiliation_strings":["Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea"],"affiliations":[{"raw_affiliation_string":"Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea","institution_ids":["https://openalex.org/I4210101891","https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079514740","display_name":"Yongdeuk Hwang","orcid":"https://orcid.org/0000-0002-0068-7151"},"institutions":[{"id":"https://openalex.org/I4210101891","display_name":"Korea Institute of Brain Science","ror":"https://ror.org/017stnw60","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210101891"]},{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yongdeuk Hwang","raw_affiliation_strings":["Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea"],"affiliations":[{"raw_affiliation_string":"Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea","institution_ids":["https://openalex.org/I4210101891","https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081247408","display_name":"Sunjae Lee","orcid":"https://orcid.org/0000-0002-6428-5936"},"institutions":[{"id":"https://openalex.org/I4210101891","display_name":"Korea Institute of Brain Science","ror":"https://ror.org/017stnw60","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210101891"]},{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sunjae Lee","raw_affiliation_strings":["Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea"],"affiliations":[{"raw_affiliation_string":"Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea","institution_ids":["https://openalex.org/I4210101891","https://openalex.org/I157485424"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037879375","display_name":"Doheon Lee","orcid":"https://orcid.org/0000-0001-9070-4316"},"institutions":[{"id":"https://openalex.org/I4210101891","display_name":"Korea Institute of Brain Science","ror":"https://ror.org/017stnw60","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210101891"]},{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Doheon Lee","raw_affiliation_strings":["Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea"],"affiliations":[{"raw_affiliation_string":"Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea","institution_ids":["https://openalex.org/I4210101891","https://openalex.org/I157485424"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033201097"],"corresponding_institution_ids":["https://openalex.org/I157485424","https://openalex.org/I4210101891"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925},"fwci":3.6987,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.93318359,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"13","issue":"S1","first_page":"S4","last_page":"S4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6612342596054077},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5221355557441711},{"id":"https://openalex.org/keywords/rotation-formalisms-in-three-dimensions","display_name":"Rotation formalisms in three dimensions","score":0.4700157940387726},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.45438137650489807},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.4247097671031952},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.41324174404144287},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.34821927547454834},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33364206552505493},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2794496715068817},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.2774538993835449},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11716380715370178}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6612342596054077},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5221355557441711},{"id":"https://openalex.org/C171018156","wikidata":"https://www.wikidata.org/wiki/Q7370306","display_name":"Rotation formalisms in three dimensions","level":2,"score":0.4700157940387726},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.45438137650489807},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.4247097671031952},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.41324174404144287},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.34821927547454834},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33364206552505493},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2794496715068817},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2774538993835449},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11716380715370178},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1472-6947-13-s1-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-13-s1-s4","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-13-S1-S4","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:23566173","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23566173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:europepmc.org:2619876","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3618249","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3618249","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3618249","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1472-6947-13-s1-s4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1472-6947-13-s1-s4","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/1472-6947-13-S1-S4","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7599999904632568,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G3034753964","display_name":null,"funder_award_id":"grant","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G87195064","display_name":null,"funder_award_id":"86964","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2101194067.pdf","grobid_xml":"https://content.openalex.org/works/W2101194067.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W323766208","https://openalex.org/W605068603","https://openalex.org/W1522668200","https://openalex.org/W1554646488","https://openalex.org/W1657478053","https://openalex.org/W1703438007","https://openalex.org/W1988327939","https://openalex.org/W1999892605","https://openalex.org/W2004881888","https://openalex.org/W2019020805","https://openalex.org/W2038961236","https://openalex.org/W2065332736","https://openalex.org/W2074192927","https://openalex.org/W2087312216","https://openalex.org/W2102382908","https://openalex.org/W2104067072","https://openalex.org/W2105536900","https://openalex.org/W2116566535","https://openalex.org/W2135009079","https://openalex.org/W2144063122","https://openalex.org/W2151251638","https://openalex.org/W2154024784","https://openalex.org/W2156779720","https://openalex.org/W2158293950","https://openalex.org/W2165958420","https://openalex.org/W2166199281","https://openalex.org/W2168258971","https://openalex.org/W2169815691","https://openalex.org/W2611943439","https://openalex.org/W3145246229","https://openalex.org/W4237095724","https://openalex.org/W4249774886","https://openalex.org/W4251538155"],"related_works":["https://openalex.org/W57206970","https://openalex.org/W3196191855","https://openalex.org/W1950785758","https://openalex.org/W4235091896","https://openalex.org/W2023896637","https://openalex.org/W2185981755","https://openalex.org/W2498253392","https://openalex.org/W2996527951","https://openalex.org/W1539846681","https://openalex.org/W1532035848"],"abstract_inverted_index":{"We":[0],"believe":[1],"that":[2],"our":[3],"simulation":[4],"would":[5,30],"help":[6],"to":[7,20],"understand":[8],"drug":[9,13],"mechanism":[10],"for":[11,25,33],"the":[12],"development":[14],"and":[15],"provide":[16],"a":[17],"new":[18,26],"way":[19],"effectively":[21],"apply":[22],"existing":[23],"drugs":[24],"target.":[27],"It":[28],"also":[29],"give":[31],"insight":[32],"identifying":[34],"effective":[35],"combination":[36],"drugs.":[37]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}