{"id":"https://openalex.org/W1969624577","doi":"https://doi.org/10.1186/1471-2342-13-9","title":"Histological image classification using biologically interpretable shape-based features","display_name":"Histological image classification using biologically interpretable shape-based features","publication_year":2013,"publication_date":"2013-03-13","ids":{"openalex":"https://openalex.org/W1969624577","doi":"https://doi.org/10.1186/1471-2342-13-9","mag":"1969624577","pmid":"https://pubmed.ncbi.nlm.nih.gov/23497380"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2342-13-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2342-13-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/1471-2342-13-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/1471-2342-13-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111775666","display_name":"Sonal Kothari","orcid":null},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonal Kothari","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074230084","display_name":"John H. Phan","orcid":"https://orcid.org/0000-0002-4670-2660"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H Phan","raw_affiliation_strings":["Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112081743","display_name":"Andrew N. Young","orcid":null},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210092882","display_name":"Grady Health System","ror":"https://ror.org/00k1xr956","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210092882"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew N Young","raw_affiliation_strings":["Grady Health System, Atlanta, GA, USA","Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grady Health System, Atlanta, GA, USA","institution_ids":["https://openalex.org/I4210092882"]},{"raw_affiliation_string":"Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030096887","display_name":"May D. Wang","orcid":"https://orcid.org/0000-0003-3961-3608"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"May D Wang","raw_affiliation_strings":["Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA","Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030096887"],"corresponding_institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":6.9211,"has_fulltext":true,"cited_by_count":69,"citation_normalized_percentile":{"value":0.96499308,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"13","issue":"1","first_page":"9","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9563999772071838,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9563999772071838,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7156604528427124},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6246958374977112},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4814704954624176},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.4732528328895569},{"id":"https://openalex.org/keywords/contextual-image-classification","display_name":"Contextual image classification","score":0.4128142297267914},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3487408757209778}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7156604528427124},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6246958374977112},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4814704954624176},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.4732528328895569},{"id":"https://openalex.org/C75294576","wikidata":"https://www.wikidata.org/wiki/Q5165192","display_name":"Contextual image classification","level":3,"score":0.4128142297267914},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3487408757209778}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2342-13-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2342-13-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/1471-2342-13-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},{"id":"pmid:23497380","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23497380","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:2625050","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3623732","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3623732","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3623732","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Imaging","raw_type":"Text"},{"id":"pmh:oai:smartech.gatech.edu:1853/47411","is_oa":true,"landing_page_url":"http://hdl.handle.net/1853/47411","pdf_url":null,"source":{"id":"https://openalex.org/S4377196313","display_name":"SMARTech Repository (Georgia Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I130701444","host_organization_name":"Georgia Institute of Technology","host_organization_lineage":["https://openalex.org/I130701444"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2342-13-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2342-13-9","pdf_url":"https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/1471-2342-13-9","source":{"id":"https://openalex.org/S6505649","display_name":"BMC Medical Imaging","issn_l":"1471-2342","issn":["1471-2342"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.7300000190734863,"id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G4333597348","display_name":null,"funder_award_id":"U54CA119338","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8431449065","display_name":null,"funder_award_id":"R01CA108468","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306352","display_name":"Georgia Cancer Coalition","ror":"https://ror.org/0009gvn90"},{"id":"https://openalex.org/F4320308943","display_name":"Microsoft Research","ror":"https://ror.org/00d0nc645"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1969624577.pdf","grobid_xml":"https://content.openalex.org/works/W1969624577.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1498009869","https://openalex.org/W1535386177","https://openalex.org/W1554944419","https://openalex.org/W1565276921","https://openalex.org/W1575108487","https://openalex.org/W1736353512","https://openalex.org/W1964146567","https://openalex.org/W1970147866","https://openalex.org/W1979062697","https://openalex.org/W2008313333","https://openalex.org/W2025183726","https://openalex.org/W2028466048","https://openalex.org/W2029820997","https://openalex.org/W2043318546","https://openalex.org/W2044465660","https://openalex.org/W2051688318","https://openalex.org/W2052101737","https://openalex.org/W2054682837","https://openalex.org/W2058490961","https://openalex.org/W2063586392","https://openalex.org/W2087347434","https://openalex.org/W2094599926","https://openalex.org/W2099796132","https://openalex.org/W2101061221","https://openalex.org/W2103243046","https://openalex.org/W2107693148","https://openalex.org/W2110059894","https://openalex.org/W2111933145","https://openalex.org/W2124155137","https://openalex.org/W2126846422","https://openalex.org/W2131987814","https://openalex.org/W2136241689","https://openalex.org/W2138776109","https://openalex.org/W2141182111","https://openalex.org/W2143093135","https://openalex.org/W2144647583","https://openalex.org/W2147650443","https://openalex.org/W2153635508","https://openalex.org/W2157239837","https://openalex.org/W2160633263","https://openalex.org/W2168002178","https://openalex.org/W2787894218","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2772917594","https://openalex.org/W2036807459","https://openalex.org/W2058170566","https://openalex.org/W2755342338","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407","https://openalex.org/W2079911747","https://openalex.org/W1969923398"],"abstract_inverted_index":{"BACKGROUND:":[0],"Automatic":[1],"cancer":[2,38],"diagnostic":[3,119,172,218],"systems":[4],"based":[5],"on":[6],"histological":[7,31,77,188,212],"image":[8,101],"classification":[9,75],"are":[10,34,168],"important":[11],"for":[12,23,36,61,74,154,204],"improving":[13],"therapeutic":[14,220],"decisions.":[15,221],"Previous":[16],"studies":[17],"propose":[18],"textural":[19],"and":[20,40,96,102,130,196,219],"morphological":[21,129],"features":[22,27,47,60,73,88,105],"such":[24],"systems.":[25],"These":[26],"capture":[28,90],"patterns":[29],"in":[30,99,217],"images":[32,191],"that":[33,89,122,165],"useful":[35],"both":[37],"grading":[39],"subtyping.":[41],"However,":[42],"because":[43],"many":[44],"of":[45,69,76,93,116,123,141,181,187],"these":[46,59,104,166],"lack":[48],"a":[49,107],"clear":[50],"biological":[51,179],"interpretation,":[52],"pathologists":[53,216],"may":[54],"be":[55,208],"reluctant":[56],"to":[57,121,210,214],"adopt":[58],"clinical":[62],"diagnosis.":[63],"METHODS:":[64],"We":[65,111,148],"examine":[66],"the":[67,91,113,117,150,160],"utility":[68],"biologically":[70,198],"interpretable":[71],"shape-based":[72,87,118,135,205],"renal":[78,156,182,189],"tumor":[79,157,190],"images.":[80],"Using":[81],"Fourier":[82],"shape":[83],"descriptors,":[84],"we":[85],"extract":[86],"distribution":[92],"stain-enhanced":[94],"cellular":[95],"tissue":[97],"structures":[98],"each":[100,155],"evaluate":[103],"using":[106,127],"multi-class":[108],"prediction":[109],"model.":[110],"compare":[112],"predictive":[114],"performance":[115],"model":[120],"traditional":[124,146],"models,":[125],"i.e.,":[126],"textural,":[128],"topological":[131],"features.":[132,162,201],"RESULTS:":[133],"The":[134],"model,":[136],"with":[137,177],"an":[138],"average":[139],"accuracy":[140],"77%,":[142],"outperforms":[143],"or":[144],"complements":[145],"models.":[147],"identify":[149],"most":[151],"informative":[152],"shapes":[153,167],"subtype":[158],"from":[159],"top-selected":[161],"Results":[163],"suggest":[164],"not":[169],"only":[170],"accurate":[171],"features,":[173],"but":[174],"also":[175],"correlate":[176],"known":[178],"characteristics":[180],"tumors.":[183],"CONCLUSIONS:":[184],"Shape-based":[185],"analysis":[186,206],"accurately":[192],"classifies":[193],"disease":[194],"subtypes":[195],"reveals":[197],"insightful":[199],"discriminatory":[200],"This":[202],"method":[203],"can":[207],"extended":[209],"other":[211],"datasets":[213],"aid":[215]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}