{"id":"https://openalex.org/W2124410431","doi":"https://doi.org/10.1186/1471-2105-9-530","title":"ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data","display_name":"ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data","publication_year":2008,"publication_date":"2008-12-01","ids":{"openalex":"https://openalex.org/W2124410431","doi":"https://doi.org/10.1186/1471-2105-9-530","mag":"2124410431","pmid":"https://pubmed.ncbi.nlm.nih.gov/19077204"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-530","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-530","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-530","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-530","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042142985","display_name":"Nodin Weddington","orcid":null},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]},{"id":"https://openalex.org/I1323276237","display_name":"Florida A&M University - Florida State University College of Engineering","ror":"https://ror.org/01v4tq883","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165","https://openalex.org/I1323276237","https://openalex.org/I8248082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nodin Weddington","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida 32306, USA. weddington@bio.fsu.edu","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida 32306, USA. weddington@bio.fsu.edu","institution_ids":["https://openalex.org/I103163165","https://openalex.org/I1323276237"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010396578","display_name":"Alexander Stuy","orcid":null},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander Stuy","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","institution_ids":["https://openalex.org/I103163165"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042749137","display_name":"Ichiro Hiratani","orcid":"https://orcid.org/0000-0003-3710-3540"},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ichiro Hiratani","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","institution_ids":["https://openalex.org/I103163165"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037951351","display_name":"Tyrone Ryba","orcid":"https://orcid.org/0009-0001-0216-897X"},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyrone Ryba","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","institution_ids":["https://openalex.org/I103163165"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068100550","display_name":"Tomoki Yokochi","orcid":null},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tomoki Yokochi","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","institution_ids":["https://openalex.org/I103163165"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020541064","display_name":"David M. Gilbert","orcid":"https://orcid.org/0000-0001-8087-9737"},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David M Gilbert","raw_affiliation_strings":["Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","Department of Biological Sciences, Florida State University, Tallahassee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, Florida, 32306, USA","institution_ids":["https://openalex.org/I103163165"]},{"raw_affiliation_string":"Department of Biological Sciences, Florida State University, Tallahassee, USA","institution_ids":["https://openalex.org/I103163165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5020541064"],"corresponding_institution_ids":["https://openalex.org/I103163165"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.5445,"has_fulltext":true,"cited_by_count":92,"citation_normalized_percentile":{"value":0.82381166,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"530","last_page":"530"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9749000072479248,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9749000072479248,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome-browser","display_name":"Genome browser","score":0.7167437672615051},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6767705082893372},{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.6227236986160278},{"id":"https://openalex.org/keywords/replication","display_name":"Replication (statistics)","score":0.571142315864563},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5049646496772766},{"id":"https://openalex.org/keywords/download","display_name":"Download","score":0.4584898352622986},{"id":"https://openalex.org/keywords/origin-of-replication","display_name":"Origin of replication","score":0.4461447596549988},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3472902178764343},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33044230937957764},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3084072470664978},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.2695598900318146},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.23264023661613464},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.22559037804603577},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09537461400032043}],"concepts":[{"id":"https://openalex.org/C2781148417","wikidata":"https://www.wikidata.org/wiki/Q5533486","display_name":"Genome browser","level":5,"score":0.7167437672615051},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6767705082893372},{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.6227236986160278},{"id":"https://openalex.org/C12590798","wikidata":"https://www.wikidata.org/wiki/Q3933199","display_name":"Replication (statistics)","level":2,"score":0.571142315864563},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5049646496772766},{"id":"https://openalex.org/C2780154274","wikidata":"https://www.wikidata.org/wiki/Q7126717","display_name":"Download","level":2,"score":0.4584898352622986},{"id":"https://openalex.org/C58337764","wikidata":"https://www.wikidata.org/wiki/Q976651","display_name":"Origin of replication","level":4,"score":0.4461447596549988},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3472902178764343},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33044230937957764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3084072470664978},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.2695598900318146},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.23264023661613464},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22559037804603577},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09537461400032043},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-9-530","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-530","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-530","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19077204","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19077204","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:6db34f786a9a42b797c21c5c4e2f8da2","is_oa":false,"landing_page_url":"https://doaj.org/article/6db34f786a9a42b797c21c5c4e2f8da2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 530 (2008)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2636809","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2636809","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-530","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-530","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-530","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5699999928474426,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2124410431.pdf","grobid_xml":"https://content.openalex.org/works/W2124410431.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W597254039","https://openalex.org/W1948275303","https://openalex.org/W1972148236","https://openalex.org/W1975210970","https://openalex.org/W1987659565","https://openalex.org/W2010959906","https://openalex.org/W2013559800","https://openalex.org/W2034037318","https://openalex.org/W2037632104","https://openalex.org/W2038783223","https://openalex.org/W2042042150","https://openalex.org/W2044781455","https://openalex.org/W2053071361","https://openalex.org/W2062118486","https://openalex.org/W2062208966","https://openalex.org/W2064568975","https://openalex.org/W2072211338","https://openalex.org/W2085326257","https://openalex.org/W2098641882","https://openalex.org/W2102304447","https://openalex.org/W2102599158","https://openalex.org/W2104978512","https://openalex.org/W2107663898","https://openalex.org/W2114169525","https://openalex.org/W2114722680","https://openalex.org/W2123488018","https://openalex.org/W2124696903","https://openalex.org/W2132546310","https://openalex.org/W2133442931","https://openalex.org/W2141269919","https://openalex.org/W2141633437","https://openalex.org/W2142769704","https://openalex.org/W2143922456","https://openalex.org/W2144141448","https://openalex.org/W2149407399","https://openalex.org/W2159342107","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2944823289","https://openalex.org/W3037018281","https://openalex.org/W2972592048","https://openalex.org/W3138117676","https://openalex.org/W2581212852","https://openalex.org/W2329795915","https://openalex.org/W3092268165","https://openalex.org/W2175953840","https://openalex.org/W4213365651","https://openalex.org/W4229585093"],"abstract_inverted_index":{"BACKGROUND:":[0],"Eukaryotic":[1],"DNA":[2],"replication":[3,39,49,72,222],"is":[4,50,93,210,236],"regulated":[5],"at":[6],"the":[7,133,218,252,257,276],"level":[8],"of":[9,38,47,54,70,89,221,249,259,264],"large":[10],"chromosomal":[11],"domains":[12,25],"(0.5-5":[13],"megabases":[14],"in":[15,27,224],"mammals)":[16],"within":[17],"which":[18,197],"replicons":[19],"are":[20,116],"activated":[21],"relatively":[22],"synchronously.":[23],"These":[24],"replicate":[26],"a":[28,51,65,127,150,211,272],"specific":[29,55],"temporal":[30,45],"order":[31,46],"during":[32],"S-phase":[33],"and":[34,81,92,131,201,213,235,239],"our":[35],"genome-wide":[36,71,98,143,232],"analyses":[37],"timing":[40,73,223],"have":[41,60,148],"demonstrated":[42],"that":[43,154],"this":[44],"domain":[48],"stable":[52],"property":[53,99],"cell":[56,79,226],"types.":[57],"RESULTS:":[58],"We":[59],"developed":[61],"ReplicationDomain":[62,209],"http://www.replicationdomain.org":[63],"as":[64,136,228,230],"web-based":[66],"database":[67,84],"for":[68,126,205,275],"analysis":[69],"maps":[74],"(replication":[75],"profiles)":[76],"from":[77],"various":[78,225],"lines":[80],"species.":[82],"This":[83],"also":[85],"provides":[86],"comparative":[87,219],"information":[88],"transcriptional":[90],"expression":[91],"configured":[94],"to":[95,158,216],"display":[96,122],"any":[97],"(for":[100],"instance,":[101],"ChIP-Chip":[102],"or":[103,139,185,190,262],"ChIP-Seq":[104],"data)":[105],"via":[106],"an":[107],"interactive":[108],"web":[109],"interface.":[110],"Our":[111],"published":[112,189],"microarray":[113],"data":[114,124,134,144,162,174,193,206,253,265],"sets":[115,125,175,194,266],"publicly":[117,195],"available.":[118],"Users":[119],"may":[120,168],"graphically":[121],"these":[123],"selected":[128],"genomic":[129],"region":[130],"download":[132,141],"displayed":[135],"text":[137],"files,":[138],"alternatively,":[140],"complete":[142],"sets.":[145,163],"Furthermore,":[146,251],"we":[147],"implemented":[149],"user":[151],"registration":[152],"system":[153],"allows":[155],"registered":[156,166,183,268],"users":[157,167,269],"upload":[159,254],"their":[160,173,188],"own":[161],"Upon":[164],"uploading,":[165],"choose":[169],"to:":[170],"(1)":[171],"view":[172],"privately":[176],"without":[177],"sharing;":[178],"(2)":[179],"share":[180],"with":[181,256],"other":[182,231],"users;":[184],"(3)":[186],"make":[187],"\"in":[191],"press\"":[192],"available,":[196],"can":[198],"fulfill":[199],"journal":[200],"funding":[202],"agencies'":[203],"requirements":[204],"sharing.":[207],"CONCLUSION:":[208],"novel":[212],"powerful":[214],"tool":[215],"facilitate":[217],"visualization":[220],"types":[227],"well":[229],"chromatin":[233],"features":[234],"considerably":[237],"faster":[238],"more":[240],"convenient":[241],"than":[242],"existing":[243],"browsers":[244],"when":[245],"viewing":[246,261],"multi-megabase":[247],"segments":[248],"chromosomes.":[250],"function":[255],"option":[258],"private":[260],"sharing":[263],"between":[267],"should":[270],"be":[271],"valuable":[273],"resource":[274],"scientific":[277],"community.":[278]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":13}],"updated_date":"2026-06-20T22:02:38.213706","created_date":"2025-10-10T00:00:00"}