{"id":"https://openalex.org/W2114090084","doi":"https://doi.org/10.1186/1471-2105-9-414","title":"Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach","display_name":"Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach","publication_year":2008,"publication_date":"2008-10-04","ids":{"openalex":"https://openalex.org/W2114090084","doi":"https://doi.org/10.1186/1471-2105-9-414","mag":"2114090084","pmid":"https://pubmed.ncbi.nlm.nih.gov/18834544"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-414","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-414","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-414","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-414","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007572142","display_name":"Firoz Anwar","orcid":"https://orcid.org/0000-0002-4980-0880"},"institutions":[{"id":"https://openalex.org/I885507782","display_name":"East West University","ror":"https://ror.org/05p0tzt32","country_code":"BD","type":"education","lineage":["https://openalex.org/I885507782"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Firoz Anwar","raw_affiliation_strings":["Department of Computer Science and Engineering, East West University, Bangladesh. fanwar@ewubd.edu","Department of Computer Science and Engineering (East West University, Bangladesh)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, East West University, Bangladesh. fanwar@ewubd.edu","institution_ids":["https://openalex.org/I885507782"]},{"raw_affiliation_string":"Department of Computer Science and Engineering (East West University, Bangladesh)","institution_ids":["https://openalex.org/I885507782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021710415","display_name":"Syed Murtuza Baker","orcid":"https://orcid.org/0000-0002-6633-333X"},"institutions":[{"id":"https://openalex.org/I885507782","display_name":"East West University","ror":"https://ror.org/05p0tzt32","country_code":"BD","type":"education","lineage":["https://openalex.org/I885507782"]}],"countries":["BD"],"is_corresponding":true,"raw_author_name":"Syed Murtuza Baker","raw_affiliation_strings":["Department of Computer Science and Engineering, East West University, Bangladesh","Department of Computer Science and Engineering (East West University, Bangladesh)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, East West University, Bangladesh","institution_ids":["https://openalex.org/I885507782"]},{"raw_affiliation_string":"Department of Computer Science and Engineering (East West University, Bangladesh)","institution_ids":["https://openalex.org/I885507782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083849969","display_name":"Taskeed Jabid","orcid":"https://orcid.org/0000-0002-8249-9567"},"institutions":[{"id":"https://openalex.org/I885507782","display_name":"East West University","ror":"https://ror.org/05p0tzt32","country_code":"BD","type":"education","lineage":["https://openalex.org/I885507782"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Taskeed Jabid","raw_affiliation_strings":["Department of Computer Science and Engineering, East West University, Bangladesh","Department of Computer Science and Engineering (East West University, Bangladesh)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, East West University, Bangladesh","institution_ids":["https://openalex.org/I885507782"]},{"raw_affiliation_string":"Department of Computer Science and Engineering (East West University, Bangladesh)","institution_ids":["https://openalex.org/I885507782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061480012","display_name":"Md Mehedi Hasan","orcid":"https://orcid.org/0000-0003-4952-0739"},"institutions":[{"id":"https://openalex.org/I205746353","display_name":"University of Dhaka","ror":"https://ror.org/05wv2vq37","country_code":"BD","type":"education","lineage":["https://openalex.org/I205746353"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Md Mehedi Hasan","raw_affiliation_strings":["Department of Genetic Engineering and Biotechnology, University of Dhaka, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Engineering and Biotechnology, University of Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205746353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111187876","display_name":"Mohammad Shoyaib","orcid":null},"institutions":[{"id":"https://openalex.org/I205746353","display_name":"University of Dhaka","ror":"https://ror.org/05wv2vq37","country_code":"BD","type":"education","lineage":["https://openalex.org/I205746353"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Mohammad Shoyaib","raw_affiliation_strings":["Institute of Information Technology, University of Dhaka, Bangladesh","Institute of Information Technology, University of Dhaka, , Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Information Technology, University of Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205746353"]},{"raw_affiliation_string":"Institute of Information Technology, University of Dhaka, , Bangladesh","institution_ids":["https://openalex.org/I205746353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004989229","display_name":"Haseena Khan","orcid":"https://orcid.org/0000-0003-4643-4106"},"institutions":[{"id":"https://openalex.org/I205746353","display_name":"University of Dhaka","ror":"https://ror.org/05wv2vq37","country_code":"BD","type":"education","lineage":["https://openalex.org/I205746353"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Haseena Khan","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh","Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205746353"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh#TAB#","institution_ids":["https://openalex.org/I205746353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063668889","display_name":"Ray Walshe","orcid":"https://orcid.org/0000-0002-1804-5288"},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Ray Walshe","raw_affiliation_strings":["Biocomputation Research Group, Dublin City University, Ireland","Biocomputation Research Group, Dublin City University, , Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biocomputation Research Group, Dublin City University, Ireland","institution_ids":["https://openalex.org/I42934936"]},{"raw_affiliation_string":"Biocomputation Research Group, Dublin City University, , Ireland","institution_ids":["https://openalex.org/I42934936"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021710415","https://openalex.org/A5063668889"],"corresponding_institution_ids":["https://openalex.org/I42934936","https://openalex.org/I885507782"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.0402,"has_fulltext":true,"cited_by_count":50,"citation_normalized_percentile":{"value":0.75601193,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"414","last_page":"414"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.8312000036239624,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.8312000036239624,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.14399999380111694,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5764134526252747},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.508342444896698},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4365392327308655},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43085533380508423},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4040377736091614},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3384287357330322},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.32806509733200073},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.17167574167251587},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.14579102396965027}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5764134526252747},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.508342444896698},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4365392327308655},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43085533380508423},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4040377736091614},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3384287357330322},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32806509733200073},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17167574167251587},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14579102396965027}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-9-414","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-414","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-414","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18834544","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18834544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2575220","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2575220","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:39c824ebdc8543bdbc3e579c9992fed2","is_oa":true,"landing_page_url":"https://doaj.org/article/39c824ebdc8543bdbc3e579c9992fed2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 414 (2008)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-414","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-414","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-414","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5400000214576721,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2114090084.pdf","grobid_xml":"https://content.openalex.org/works/W2114090084.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1529355444","https://openalex.org/W1803949961","https://openalex.org/W1973468493","https://openalex.org/W1976927254","https://openalex.org/W1999966058","https://openalex.org/W2003463914","https://openalex.org/W2060527661","https://openalex.org/W2075793022","https://openalex.org/W2087347434","https://openalex.org/W2096329971","https://openalex.org/W2097353028","https://openalex.org/W2101163218","https://openalex.org/W2106756765","https://openalex.org/W2109943925","https://openalex.org/W2113197426","https://openalex.org/W2114332734","https://openalex.org/W2115358825","https://openalex.org/W2121400095","https://openalex.org/W2124195715","https://openalex.org/W2124332179","https://openalex.org/W2130919037","https://openalex.org/W2132618831","https://openalex.org/W2133449910","https://openalex.org/W2134193442","https://openalex.org/W2146975493","https://openalex.org/W2165646896","https://openalex.org/W2165884762","https://openalex.org/W2169351355","https://openalex.org/W2330066387","https://openalex.org/W4229799243"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2415545834","https://openalex.org/W2069695727","https://openalex.org/W2150084125","https://openalex.org/W2118505788","https://openalex.org/W1802639773","https://openalex.org/W1972196578","https://openalex.org/W1490878237","https://openalex.org/W1542823905","https://openalex.org/W2990314835"],"abstract_inverted_index":{"BACKGROUND:":[0],"Eukaryotic":[1],"promoter":[2,59,152,245],"prediction":[3,50,60],"using":[4,246],"computational":[5,16],"analysis":[6,52],"techniques":[7,47],"is":[8,19,86,127,223],"one":[9],"of":[10,31,53,96,114,178,192,244,272],"the":[11,49,111,115,169,270],"most":[12],"difficult":[13],"jobs":[14],"in":[15,38,55,129,134,260,269,289],"genomics":[17],"that":[18,98,220,257],"essential":[20],"for":[21,34,43,48,92,196,201,206,211,217,291],"constructing":[22],"and":[23,46,51,62,153,166,183,189,194,199,204,209,213,215,230,254],"understanding":[24],"genetic":[25],"regulatory":[26],"networks.":[27],"The":[28,186,251],"increased":[29],"availability":[30],"sequence":[32],"data":[33],"various":[35],"eukaryotic":[36,56,293],"organisms":[37],"recent":[39],"years":[40],"has":[41,172],"necessitated":[42],"better":[44,90,232],"tools":[45,63],"promoters":[54,97,276,288],"sequences.":[57,156],"Many":[58],"methods":[61,85,265],"have":[64,71],"been":[65],"developed":[66],"to":[67,73,81,87,149,161,226,278,286],"date":[68],"but":[69],"they":[70],"yet":[72],"provide":[74],"acceptable":[75],"predictive":[76,112],"performance.":[77],"One":[78],"obvious":[79],"criteria":[80],"improve":[82],"on":[83],"current":[84],"devise":[88],"a":[89,124,137,142],"system":[91],"selecting":[93],"appropriate":[94],"features":[95],"distinguish":[99,150],"them":[100],"from":[101],"non-promoters.":[102],"Secondly":[103],"improved":[104],"performance":[105,233],"can":[106,266,283],"be":[107,267,284],"achieved":[108],"by":[109],"enhancing":[110],"ability":[113],"machine":[116],"learning":[117],"algorithms":[118],"used.":[119],"RESULTS:":[120],"In":[121],"this":[122,159,221,239],"paper,":[123],"novel":[125],"approach":[126,160,282],"presented":[128],"which":[130],"128":[131],"4-mer":[132,258],"motifs":[133],"conjunction":[135,261],"with":[136,262],"non-linear":[138],"machine-learning":[139,264],"algorithm":[140],"utilising":[141],"Support":[143],"Vector":[144],"Machine":[145],"(SVM)":[146],"are":[147],"used":[148],"between":[151],"non-promoter":[154],"DNA":[155],"By":[157],"applying":[158],"plant,":[162],"Drosophila,":[163],"human,":[164],"mouse":[165,212],"rat":[167,218],"sequences,":[168],"classification":[170],"model":[171,240],"showed":[173],"7-fold":[174],"cross-validation":[175],"percentage":[176],"accuracies":[177],"83.81%,":[179],"94.82%,":[180],"91.25%,":[181],"90.77%":[182],"82.35%":[184],"respectively.":[185],"high":[187,252],"sensitivity":[188,253],"specificity":[190,255],"value":[191],"0.86":[193],"0.90":[195],"plant;":[197],"0.96":[198],"0.92":[200,205],"Drosophila;":[202],"0.88":[203],"human;":[207],"0.78":[208],"0.84":[210],"0.82":[214],"0.80":[216],"demonstrate":[219],"technique":[222],"less":[224],"prone":[225],"false":[227],"positive":[228],"results":[229],"exhibits":[231],"than":[234],"many":[235],"other":[236,279,292],"tools.":[237],"Moreover,":[238],"successfully":[241],"identifies":[242],"location":[243],"TATA":[247],"weight":[248],"matrix.":[249],"CONCLUSION:":[250],"indicate":[256],"frequencies":[259],"supervised":[263],"beneficial":[268],"identification":[271],"RNA":[273],"pol":[274],"II":[275],"comparative":[277],"methods.":[280],"This":[281],"extended":[285],"identify":[287],"sequences":[290],"genomes.":[294]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}