{"id":"https://openalex.org/W2105379381","doi":"https://doi.org/10.1186/1471-2105-9-342","title":"SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool","display_name":"SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool","publication_year":2008,"publication_date":"2008-08-15","ids":{"openalex":"https://openalex.org/W2105379381","doi":"https://doi.org/10.1186/1471-2105-9-342","mag":"2105379381","pmid":"https://pubmed.ncbi.nlm.nih.gov/18706080"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-342","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-342","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-342","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-342","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087731845","display_name":"Zhike Zi","orcid":"https://orcid.org/0000-0002-7601-915X"},"institutions":[{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Zhike Zi","raw_affiliation_strings":["Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de","Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016643106","display_name":"Yanan Zheng","orcid":"https://orcid.org/0000-0002-9823-0191"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanan Zheng","raw_affiliation_strings":["Entelos Inc., 110 Marsh Drive, Foster City, CA, 94404, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Entelos Inc., 110 Marsh Drive, Foster City, CA, 94404, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048545593","display_name":"Ann E. Rundell","orcid":null},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ann E Rundell","raw_affiliation_strings":["Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003799374","display_name":"Edda Klipp","orcid":"https://orcid.org/0000-0002-0567-7075"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Edda Klipp","raw_affiliation_strings":["Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany","Theoretical Biophysics, Humboldt University Berlin, Institute for Biology, Invalidenstr, 42, 10115, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany","institution_ids":["https://openalex.org/I4210142260"]},{"raw_affiliation_string":"Theoretical Biophysics, Humboldt University Berlin, Institute for Biology, Invalidenstr, 42, 10115, Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5003799374","https://openalex.org/A5048545593"],"corresponding_institution_ids":["https://openalex.org/I219193219","https://openalex.org/I39343248","https://openalex.org/I4210142260"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":1219,"currency":"EUR","value_usd":1314},"fwci":4.0315,"has_fulltext":true,"cited_by_count":80,"citation_normalized_percentile":{"value":0.94611313,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"342","last_page":"342"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.946399986743927,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.946399986743927,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.0406000018119812,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sbml","display_name":"SBML","score":0.9950380325317383},{"id":"https://openalex.org/keywords/markup-language","display_name":"Markup language","score":0.8034180402755737},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.749902606010437},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5611436367034912},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5399603247642517},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5375956892967224},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.48515185713768005},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.45496779680252075},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.45223942399024963},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.24068990349769592},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.18783318996429443},{"id":"https://openalex.org/keywords/xml","display_name":"XML","score":0.1323305368423462},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.08024021983146667}],"concepts":[{"id":"https://openalex.org/C87186988","wikidata":"https://www.wikidata.org/wiki/Q452197","display_name":"SBML","level":4,"score":0.9950380325317383},{"id":"https://openalex.org/C45874996","wikidata":"https://www.wikidata.org/wiki/Q37045","display_name":"Markup language","level":3,"score":0.8034180402755737},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.749902606010437},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5611436367034912},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5399603247642517},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5375956892967224},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.48515185713768005},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.45496779680252075},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.45223942399024963},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.24068990349769592},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18783318996429443},{"id":"https://openalex.org/C8797682","wikidata":"https://www.wikidata.org/wiki/Q2115","display_name":"XML","level":2,"score":0.1323305368423462},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.08024021983146667},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/1471-2105-9-342","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-342","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-342","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18706080","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18706080","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pure.mpg.de:item_1584437","is_oa":true,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-0010-7F54-7","pdf_url":"http://hdl.handle.net/11858/00-001M-0000-0010-7F54-7","source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:docs.lib.purdue.edu:bmepubs-1015","is_oa":false,"landing_page_url":"https://docs.lib.purdue.edu/bmepubs/16","pdf_url":null,"source":{"id":"https://openalex.org/S4377196310","display_name":"Purdue e-Pubs (Purdue University System)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801333002","host_organization_name":"Purdue University System","host_organization_lineage":["https://openalex.org/I2801333002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Weldon School of Biomedical Engineering Faculty Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:fc2b7dd7565447e6b57a75d1f4de6772","is_oa":true,"landing_page_url":"https://doaj.org/article/fc2b7dd7565447e6b57a75d1f4de6772","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 342 (2008)","raw_type":"article"},{"id":"pmh:oai:edoc.mpg.de:412698","is_oa":false,"landing_page_url":"http://edoc.mpg.de/412698","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, v.15, 342-342 (2008)","raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2529325","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2529325","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-342","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-342","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-342","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320327553","display_name":"International Max Planck Research School for Advanced Methods in Process and Systems Engineering","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2105379381.pdf","grobid_xml":"https://content.openalex.org/works/W2105379381.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W2805211","https://openalex.org/W339353406","https://openalex.org/W1486416230","https://openalex.org/W1576664335","https://openalex.org/W1641228030","https://openalex.org/W1964037688","https://openalex.org/W1975351609","https://openalex.org/W1979833590","https://openalex.org/W1985911638","https://openalex.org/W1986050448","https://openalex.org/W1986482900","https://openalex.org/W1987242421","https://openalex.org/W2006595428","https://openalex.org/W2009046862","https://openalex.org/W2015711590","https://openalex.org/W2034562813","https://openalex.org/W2038669746","https://openalex.org/W2039793587","https://openalex.org/W2041966847","https://openalex.org/W2042065803","https://openalex.org/W2047674748","https://openalex.org/W2065151681","https://openalex.org/W2082621456","https://openalex.org/W2089329241","https://openalex.org/W2092509730","https://openalex.org/W2093242596","https://openalex.org/W2095372251","https://openalex.org/W2101589741","https://openalex.org/W2102653059","https://openalex.org/W2107062718","https://openalex.org/W2110565551","https://openalex.org/W2111421616","https://openalex.org/W2115343689","https://openalex.org/W2117056464","https://openalex.org/W2117364474","https://openalex.org/W2124149894","https://openalex.org/W2124630954","https://openalex.org/W2126025430","https://openalex.org/W2128782793","https://openalex.org/W2137128504","https://openalex.org/W2139439234","https://openalex.org/W2139629468","https://openalex.org/W2142072523","https://openalex.org/W2166565152","https://openalex.org/W2166751342","https://openalex.org/W4252867934","https://openalex.org/W4300945981"],"related_works":["https://openalex.org/W2082621456","https://openalex.org/W2981332207","https://openalex.org/W2100525485","https://openalex.org/W2040642413","https://openalex.org/W3048335229","https://openalex.org/W2146744007","https://openalex.org/W1546010648","https://openalex.org/W2150908245","https://openalex.org/W2211443823","https://openalex.org/W2043776573"],"abstract_inverted_index":{"BACKGROUND:":[0],"It":[1],"has":[2,26],"long":[3],"been":[4],"recognized":[5],"that":[6],"sensitivity":[7,54,83,99,103,116],"analysis":[8,78,84,147],"plays":[9],"a":[10,28,63,142],"key":[11],"role":[12],"in":[13,48,118],"modeling":[14],"and":[15,18,33,79,81,111,129,154],"analyzing":[16],"cellular":[17,155],"biochemical":[19,153],"processes.":[20,39,156],"Systems":[21],"biology":[22],"markup":[23],"language":[24],"(SBML)":[25],"become":[27],"well-known":[29],"platform":[30],"for":[31,72,85,145],"coding":[32],"sharing":[34],"mathematical":[35],"models":[36,151],"of":[37,56,97,114,139,148,152],"such":[38],"However,":[40],"current":[41,92],"SBML":[42,86,150],"compatible":[43],"software":[44,66,89],"tools":[45],"are":[46],"limited":[47],"their":[49,149],"ability":[50,122],"to":[51,120,123],"perform":[52],"global":[53,82,98],"analyses":[55,100,117],"these":[57],"models.":[58,87],"RESULTS:":[59],"This":[60,88],"work":[61],"introduces":[62],"freely":[64],"downloadable,":[65],"package,":[67],"SBML-SAT,":[68],"which":[69],"implements":[70],"algorithms":[71],"simulation,":[73],"steady":[74],"state":[75],"analysis,":[76,104],"robustness":[77],"local":[80,115],"tool":[90,144],"extends":[91],"capabilities":[93],"through":[94],"its":[95,121],"execution":[96],"using":[101],"multi-parametric":[102],"partial":[105],"rank":[106],"correlation":[107],"coefficient,":[108],"SOBOL's":[109],"method,":[110],"weighted":[112],"average":[113],"addition":[119],"handle":[124],"systems":[125,140],"with":[126],"discontinuous":[127],"events":[128],"intuitive":[130],"graphical":[131],"user":[132],"interface.":[133],"CONCLUSION:":[134],"SBML-SAT":[135],"provides":[136],"the":[137,146],"community":[138],"biologists":[141],"new":[143]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":10}],"updated_date":"2026-08-04T08:18:43.703281","created_date":"2025-10-10T00:00:00"}