{"id":"https://openalex.org/W2071254403","doi":"https://doi.org/10.1186/1471-2105-9-240","title":"Estimating the size of the solution space of metabolic networks","display_name":"Estimating the size of the solution space of metabolic networks","publication_year":2008,"publication_date":"2008-05-19","ids":{"openalex":"https://openalex.org/W2071254403","doi":"https://doi.org/10.1186/1471-2105-9-240","mag":"2071254403","pmid":"https://pubmed.ncbi.nlm.nih.gov/18489757"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-240","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-240","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-240","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-240","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067371775","display_name":"Alfredo Braunstein","orcid":"https://orcid.org/0000-0002-4562-3610"},"institutions":[{"id":"https://openalex.org/I134940468","display_name":"Institute for Scientific Interchange","ror":"https://ror.org/00te2x188","country_code":"IT","type":"facility","lineage":["https://openalex.org/I134940468"]},{"id":"https://openalex.org/I177477856","display_name":"Polytechnic University of Turin","ror":"https://ror.org/00bgk9508","country_code":"IT","type":"education","lineage":["https://openalex.org/I177477856"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Alfredo Braunstein","raw_affiliation_strings":["Politecnico di Torino, Corso Duca degli Abruzzi 34, I-10129, Torino, Italy. alfredo.braunstein@polito.it","Politecnico di Torino","ISI Foundation Viale Settimio Severo 65"],"affiliations":[{"raw_affiliation_string":"Politecnico di Torino, Corso Duca degli Abruzzi 34, I-10129, Torino, Italy. alfredo.braunstein@polito.it","institution_ids":["https://openalex.org/I177477856"]},{"raw_affiliation_string":"Politecnico di Torino","institution_ids":["https://openalex.org/I177477856"]},{"raw_affiliation_string":"ISI Foundation Viale Settimio Severo 65","institution_ids":["https://openalex.org/I134940468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047259721","display_name":"Roberto Mulet","orcid":"https://orcid.org/0000-0001-5168-5116"},"institutions":[{"id":"https://openalex.org/I2656126","display_name":"University of Havana","ror":"https://ror.org/04204gr61","country_code":"CU","type":"education","lineage":["https://openalex.org/I2656126"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Roberto Mulet","raw_affiliation_strings":["\"Henri-Poincar\u00e9-Group\" of Complex Systems and Department of Theoretical Physics, Physics Faculty, University of Havana, La Habana, CP, 10400, Cuba","Henri-Poincar\u00e9-Group of Complex Systems and Department of Theoretical Physics, Physics Faculty, University of Havana, La Habana, Cuba"],"affiliations":[{"raw_affiliation_string":"\"Henri-Poincar\u00e9-Group\" of Complex Systems and Department of Theoretical Physics, Physics Faculty, University of Havana, La Habana, CP, 10400, Cuba","institution_ids":["https://openalex.org/I2656126"]},{"raw_affiliation_string":"Henri-Poincar\u00e9-Group of Complex Systems and Department of Theoretical Physics, Physics Faculty, University of Havana, La Habana, Cuba","institution_ids":["https://openalex.org/I2656126"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011435835","display_name":"Andrea Pagnani","orcid":"https://orcid.org/0000-0002-6509-0807"},"institutions":[{"id":"https://openalex.org/I134940468","display_name":"Institute for Scientific Interchange","ror":"https://ror.org/00te2x188","country_code":"IT","type":"facility","lineage":["https://openalex.org/I134940468"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Pagnani","raw_affiliation_strings":["ISI Foundation Viale Settimio Severo 65, Villa Gualino, I-10133, Torino, Italy","ISI Foundation Viale Settimio Severo 65"],"affiliations":[{"raw_affiliation_string":"ISI Foundation Viale Settimio Severo 65, Villa Gualino, I-10133, Torino, Italy","institution_ids":["https://openalex.org/I134940468"]},{"raw_affiliation_string":"ISI Foundation Viale Settimio Severo 65","institution_ids":["https://openalex.org/I134940468"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5067371775"],"corresponding_institution_ids":["https://openalex.org/I134940468","https://openalex.org/I177477856"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.3509,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.8836902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"240","last_page":"240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-network","display_name":"Metabolic network","score":0.7441565990447998},{"id":"https://openalex.org/keywords/flux-balance-analysis","display_name":"Flux balance analysis","score":0.6195888519287109},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5887027978897095},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5596388578414917},{"id":"https://openalex.org/keywords/maximization","display_name":"Maximization","score":0.48009732365608215},{"id":"https://openalex.org/keywords/affine-transformation","display_name":"Affine transformation","score":0.4774811267852783},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.4718630015850067},{"id":"https://openalex.org/keywords/metabolic-flux-analysis","display_name":"Metabolic flux analysis","score":0.4573487937450409},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.4389808177947998},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4373573660850525},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.38195863366127014},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.34875279664993286},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3028431534767151},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.19326555728912354},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11851134896278381}],"concepts":[{"id":"https://openalex.org/C101810790","wikidata":"https://www.wikidata.org/wiki/Q2263094","display_name":"Metabolic network","level":2,"score":0.7441565990447998},{"id":"https://openalex.org/C167091322","wikidata":"https://www.wikidata.org/wiki/Q5463029","display_name":"Flux balance analysis","level":2,"score":0.6195888519287109},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5887027978897095},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5596388578414917},{"id":"https://openalex.org/C2776330181","wikidata":"https://www.wikidata.org/wiki/Q18358244","display_name":"Maximization","level":2,"score":0.48009732365608215},{"id":"https://openalex.org/C92757383","wikidata":"https://www.wikidata.org/wiki/Q382497","display_name":"Affine transformation","level":2,"score":0.4774811267852783},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.4718630015850067},{"id":"https://openalex.org/C160941953","wikidata":"https://www.wikidata.org/wiki/Q6822342","display_name":"Metabolic flux analysis","level":3,"score":0.4573487937450409},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.4389808177947998},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4373573660850525},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.38195863366127014},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.34875279664993286},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3028431534767151},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.19326555728912354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11851134896278381},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007257","descriptor_name":"Information Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007257","descriptor_name":"Information Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007257","descriptor_name":"Information Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-9-240","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-240","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-240","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18489757","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18489757","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:d2d3a5539bc54c6d8eb21235f767c066","is_oa":true,"landing_page_url":"https://doaj.org/article/d2d3a5539bc54c6d8eb21235f767c066","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 240 (2008)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2483728","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2483728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-240","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-240","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-240","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2071254403.pdf","grobid_xml":"https://content.openalex.org/works/W2071254403.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W8679120","https://openalex.org/W1489298643","https://openalex.org/W1518885151","https://openalex.org/W1524662923","https://openalex.org/W1530042113","https://openalex.org/W1531327550","https://openalex.org/W1577525534","https://openalex.org/W1607198972","https://openalex.org/W1622584740","https://openalex.org/W1854875838","https://openalex.org/W1969253588","https://openalex.org/W1982531027","https://openalex.org/W1983281982","https://openalex.org/W1987679122","https://openalex.org/W1989757489","https://openalex.org/W2008875008","https://openalex.org/W2015519162","https://openalex.org/W2022083710","https://openalex.org/W2025663053","https://openalex.org/W2036759514","https://openalex.org/W2056281205","https://openalex.org/W2086196945","https://openalex.org/W2089476104","https://openalex.org/W2096245011","https://openalex.org/W2098678088","https://openalex.org/W2102164505","https://openalex.org/W2137813581","https://openalex.org/W2144885342","https://openalex.org/W2158122241","https://openalex.org/W2165674132","https://openalex.org/W2169732368","https://openalex.org/W2169913476","https://openalex.org/W2949328601","https://openalex.org/W2950654313","https://openalex.org/W3103786587","https://openalex.org/W3140660692","https://openalex.org/W3140968660","https://openalex.org/W4234356172"],"related_works":["https://openalex.org/W2133150343","https://openalex.org/W3033588432","https://openalex.org/W2963227893","https://openalex.org/W2580762423","https://openalex.org/W4299344096","https://openalex.org/W2216418212","https://openalex.org/W1991691567","https://openalex.org/W1976202310","https://openalex.org/W2416161358","https://openalex.org/W3084362230"],"abstract_inverted_index":{"We":[0],"propose":[1,72],"a":[2,19],"novel":[3],"efficient":[4,51],"distributed":[5],"algorithmic":[6,67],"strategy":[7],"to":[8,31,79],"estimate":[9],"the":[10,15,39,53],"size":[11],"and":[12,34],"shape":[13],"of":[14,18,41,55],"affine":[16],"space":[17],"non":[20],"full-dimensional":[21],"convex":[22],"polytope":[23],"in":[24,66],"high":[25],"dimensions.":[26],"The":[27,69],"method":[28],"is":[29,47],"shown":[30],"obtain,":[32],"quantitatively":[33],"qualitatively":[35],"compatible":[36],"results":[37],"with":[38],"ones":[40],"standard":[42],"algorithms":[43],"(where":[44],"this":[45],"comparison":[46],"possible)":[48],"being":[49],"still":[50],"on":[52],"analysis":[54],"large":[56],"biological":[57],"systems,":[58],"where":[59],"exact":[60],"deterministic":[61],"methods":[62],"experience":[63],"an":[64,77],"explosion":[65],"time.":[68],"algorithm":[70],"we":[71],"can":[73],"be":[74],"considered":[75],"as":[76],"alternative":[78],"Monte":[80],"Carlo":[81],"sampling":[82],"methods.":[83]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}