{"id":"https://openalex.org/W2008239800","doi":"https://doi.org/10.1186/1471-2105-9-196","title":"MPDA: Microarray pooled DNA analyzer","display_name":"MPDA: Microarray pooled DNA analyzer","publication_year":2008,"publication_date":"2008-04-15","ids":{"openalex":"https://openalex.org/W2008239800","doi":"https://doi.org/10.1186/1471-2105-9-196","mag":"2008239800","pmid":"https://pubmed.ncbi.nlm.nih.gov/18412951"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-196","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-196","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-196","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-196","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084398188","display_name":"Hsin\u2010Chou Yang","orcid":"https://orcid.org/0000-0001-6853-7881"},"institutions":[{"id":"https://openalex.org/I4210141710","display_name":"Institute of Statistical Science, Academia Sinica","ror":"https://ror.org/044gv5910","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210141710","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Hsin-Chou Yang","raw_affiliation_strings":["Institute of Statistical Science, Academia Sinica, Taipei, Taiwan. hsinchou@stat.sinica.edu.tw","Institute of Statistical, Science Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Statistical Science, Academia Sinica, Taipei, Taiwan. hsinchou@stat.sinica.edu.tw","institution_ids":["https://openalex.org/I4210141710"]},{"raw_affiliation_string":"Institute of Statistical, Science Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066033010","display_name":"Mei-Chu Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210141710","display_name":"Institute of Statistical Science, Academia Sinica","ror":"https://ror.org/044gv5910","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210141710","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Mei-Chu Huang","raw_affiliation_strings":["Institute of Statistical Science, Academia Sinica, Taipei, Taiwan","Institute of Statistical, Science Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Statistical Science, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210141710"]},{"raw_affiliation_string":"Institute of Statistical, Science Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055443250","display_name":"Ling\u2010Hui Li","orcid":"https://orcid.org/0000-0003-1302-4215"},"institutions":[{"id":"https://openalex.org/I4210096666","display_name":"Institute of Biomedical Sciences, Academia Sinica","ror":"https://ror.org/00tk6s776","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210096666","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ling-Hui Li","raw_affiliation_strings":["Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210096666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111840210","display_name":"Chien\u2010Hsing Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Hsing Lin","raw_affiliation_strings":["Department of Life Sciences and Institute of Genome Sciences, Yang-Ming University, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences and Institute of Genome Sciences, Yang-Ming University, Taipei, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055148154","display_name":"Alice L. Yu","orcid":"https://orcid.org/0000-0003-2444-0505"},"institutions":[{"id":"https://openalex.org/I4210087491","display_name":"Genomics Research Center, Academia Sinica","ror":"https://ror.org/002mmyt85","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210087491","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Alice LT Yu","raw_affiliation_strings":["Genomics Research Center, Academia Sinica, Taipei, Taiwan","Genomics Research Center Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics Research Center, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210087491"]},{"raw_affiliation_string":"Genomics Research Center Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210087491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079060579","display_name":"Mitchell B. Diccianni","orcid":"https://orcid.org/0000-0002-5017-9585"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell B Diccianni","raw_affiliation_strings":["Department of Pediatrics/Hematology Oncology, University of California, San Diego, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics/Hematology Oncology, University of California, San Diego, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115595403","display_name":"Jer\u2010Yuarn Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210096666","display_name":"Institute of Biomedical Sciences, Academia Sinica","ror":"https://ror.org/00tk6s776","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210096666","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jer-Yuarn Wu","raw_affiliation_strings":["Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210096666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050148296","display_name":"Yuan-Tsong Chen","orcid":"https://orcid.org/0000-0002-6914-4817"},"institutions":[{"id":"https://openalex.org/I4210096666","display_name":"Institute of Biomedical Sciences, Academia Sinica","ror":"https://ror.org/00tk6s776","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210096666","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yuan-Tsong Chen","raw_affiliation_strings":["Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210096666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028466052","display_name":"Cathy S.J. Fann","orcid":"https://orcid.org/0000-0001-9025-2276"},"institutions":[{"id":"https://openalex.org/I4210096666","display_name":"Institute of Biomedical Sciences, Academia Sinica","ror":"https://ror.org/00tk6s776","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210096666","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Cathy SJ Fann","raw_affiliation_strings":["Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210096666"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5028466052","https://openalex.org/A5084398188"],"corresponding_institution_ids":["https://openalex.org/I4210096666","https://openalex.org/I4210141710","https://openalex.org/I84653119"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.1686,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.80327489,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"9","issue":"1","first_page":"196","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.7570000290870667,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.7570000290870667,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.17239999771118164,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.01810000091791153,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.7564728260040283},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5716568231582642},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.5659737586975098},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5017275810241699},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.44068199396133423},{"id":"https://openalex.org/keywords/dna-profiling","display_name":"DNA profiling","score":0.4140698313713074},{"id":"https://openalex.org/keywords/spectrum-analyzer","display_name":"Spectrum analyzer","score":0.41403117775917053},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.41021305322647095},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2929614186286926},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1962309181690216},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.11216750741004944}],"concepts":[{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.7564728260040283},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5716568231582642},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.5659737586975098},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5017275810241699},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.44068199396133423},{"id":"https://openalex.org/C79386861","wikidata":"https://www.wikidata.org/wiki/Q476697","display_name":"DNA profiling","level":3,"score":0.4140698313713074},{"id":"https://openalex.org/C158007255","wikidata":"https://www.wikidata.org/wiki/Q1055222","display_name":"Spectrum analyzer","level":2,"score":0.41403117775917053},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.41021305322647095},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2929614186286926},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1962309181690216},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.11216750741004944},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-9-196","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-196","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-196","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18412951","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18412951","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:a6d867511176429c8335d4e66a425134","is_oa":false,"landing_page_url":"https://doaj.org/article/a6d867511176429c8335d4e66a425134","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 196 (2008)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2387178","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2387178","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-196","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-196","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-196","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320321041","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2008239800.pdf","grobid_xml":"https://content.openalex.org/works/W2008239800.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W48339519","https://openalex.org/W1514925303","https://openalex.org/W1519063532","https://openalex.org/W1522239197","https://openalex.org/W1522722907","https://openalex.org/W1529319215","https://openalex.org/W1590855072","https://openalex.org/W1591267872","https://openalex.org/W1698751783","https://openalex.org/W1720092910","https://openalex.org/W1797243065","https://openalex.org/W1951801079","https://openalex.org/W1970761420","https://openalex.org/W1972607125","https://openalex.org/W1974073207","https://openalex.org/W1980054283","https://openalex.org/W1981127789","https://openalex.org/W1984186679","https://openalex.org/W1989427963","https://openalex.org/W1990139289","https://openalex.org/W1994678797","https://openalex.org/W1996284475","https://openalex.org/W2002276824","https://openalex.org/W2002637589","https://openalex.org/W2003019434","https://openalex.org/W2009978569","https://openalex.org/W2018473803","https://openalex.org/W2023195692","https://openalex.org/W2026869877","https://openalex.org/W2033041275","https://openalex.org/W2038700828","https://openalex.org/W2048975453","https://openalex.org/W2052115034","https://openalex.org/W2054193808","https://openalex.org/W2054723073","https://openalex.org/W2055595065","https://openalex.org/W2058080192","https://openalex.org/W2061784450","https://openalex.org/W2066669827","https://openalex.org/W2067307077","https://openalex.org/W2068777129","https://openalex.org/W2071387002","https://openalex.org/W2087111030","https://openalex.org/W2089251117","https://openalex.org/W2093166014","https://openalex.org/W2096051150","https://openalex.org/W2096186869","https://openalex.org/W2107966042","https://openalex.org/W2108024903","https://openalex.org/W2110227850","https://openalex.org/W2110278272","https://openalex.org/W2111648591","https://openalex.org/W2112776973","https://openalex.org/W2114133792","https://openalex.org/W2118514444","https://openalex.org/W2124873881","https://openalex.org/W2125255775","https://openalex.org/W2135838393","https://openalex.org/W2144787319","https://openalex.org/W2146948473","https://openalex.org/W2151739791","https://openalex.org/W2152068169","https://openalex.org/W2155707112","https://openalex.org/W2157752701","https://openalex.org/W2159269328","https://openalex.org/W2171822179","https://openalex.org/W2188361721","https://openalex.org/W4231505042"],"related_works":["https://openalex.org/W2041540252","https://openalex.org/W2415545834","https://openalex.org/W1547158732","https://openalex.org/W3203113381","https://openalex.org/W2366558827","https://openalex.org/W170658859","https://openalex.org/W4232333928","https://openalex.org/W4233699124","https://openalex.org/W1594655861","https://openalex.org/W2753838071"],"abstract_inverted_index":{"BACKGROUND:":[0],"Microarray-based":[1],"pooled":[2,26,86,96,119,193,244,260],"DNA":[3,10,36,53,87,97,106,120,125,194,245,261],"experiments":[4],"that":[5,109,179,201,212,225,242],"combine":[6],"the":[7,33,59,80,170,240,276,281],"merits":[8],"of":[9,35,42,84,95,156,159,173,185,230],"pooling":[11],"and":[12,98,137,146,153,188,216,248,268,283],"gene":[13,45],"chip":[14,46],"technology":[15],"constitute":[16],"a":[17,92,100,253],"pivotal":[18],"advance":[19],"in":[20,233,280],"biotechnology.":[21],"This":[22],"new":[23],"technique":[24,60],"uses":[25],"DNA,":[27],"thereby":[28],"reducing":[29],"costs":[30,48],"associated":[31],"with":[32,140],"typing":[34],"from":[37,117,149],"numerous":[38],"individuals.":[39],"Moreover,":[40],"use":[41],"an":[43,62],"oligonucleotide":[44],"reduces":[47],"related":[49],"to":[50,77,112,168],"processing":[51],"various":[52],"segments":[54],"(e.g.,":[55],"primers,":[56],"reagents).":[57],"Thus,":[58],"provides":[61,252],"overall":[63],"cost-effective":[64,215],"solution":[65],"for":[66,192,218,257],"large-scale":[67],"genomic/genetic":[68],"research.":[69],"However,":[70],"few":[71],"publicly":[72],"shared":[73,141],"tools":[74],"are":[75,166,271],"available":[76,273],"systematically":[78],"analyze":[79,113],"rapidly":[81],"accumulating":[82],"volume":[83],"whole-genome":[85,124,163,259],"data.":[88,161],"RESULTS:":[89],"We":[90],"propose":[91],"generalized":[93],"concept":[94],"present":[99],"user-friendly":[101],"tool":[102],"named":[103],"Microarray":[104],"Pooled":[105],"Analyzer":[107],"(MPDA)":[108],"we":[110],"developed":[111],"hybridization":[114],"intensity":[115],"data":[116,142,164,195,262],"microarray-based":[118],"experiments.":[121],"MPDA":[122,150,180,202,213,226,277],"enables":[123],"preferential":[126,186],"amplification/hybridization":[127,187],"analysis,":[128,251],"allele":[129,206],"frequency":[130],"estimation,":[131],"association":[132,219,246],"mapping,":[133],"allelic":[134,249],"imbalance":[135,250],"detection,":[136],"permits":[138],"integration":[139],"resources":[143],"online.":[144],"Graphic":[145],"numerical":[147],"outputs":[148],"support":[151],"global":[152],"detailed":[154],"inspection":[155],"large":[157],"amounts":[158],"genomic":[160,183],"Four":[162],"analyses":[165],"used":[167],"illustrate":[169],"major":[171],"functionalities":[172],"MPDA.":[174],"The":[175,197,208,221,264],"first":[176],"analysis":[177,199,210,223,247,255],"shows":[178,224],"can":[181,203,227],"characterize":[182],"patterns":[184],"provide":[189],"calibration":[190],"information":[191],"analysis.":[196,263],"second":[198],"demonstrates":[200],"accurately":[204],"estimate":[205],"frequencies.":[207],"third":[209],"indicates":[211],"is":[214],"reliable":[217],"mapping.":[220],"final":[222],"identify":[228],"regions":[229],"chromosomal":[231],"aberration":[232],"cancer":[234],"without":[235],"paired-normal":[236],"tissue.":[237],"CONCLUSION:":[238],"MPDA,":[239],"software":[241],"integrates":[243],"convenient":[254],"system":[256],"extensive":[258],"software,":[265],"user":[266],"manual":[267],"illustrated":[269],"examples":[270],"freely":[272],"online":[274],"at":[275],"website":[278],"listed":[279],"Availability":[282],"requirements":[284],"section.":[285]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}