{"id":"https://openalex.org/W2048777227","doi":"https://doi.org/10.1186/1471-2105-9-141","title":"Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence","display_name":"Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence","publication_year":2008,"publication_date":"2008-03-05","ids":{"openalex":"https://openalex.org/W2048777227","doi":"https://doi.org/10.1186/1471-2105-9-141","mag":"2048777227","pmid":"https://pubmed.ncbi.nlm.nih.gov/18321373"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-9-141","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-141","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-141","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-141","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063632942","display_name":"Adriano Barbosa-Silva","orcid":"https://orcid.org/0000-0002-5260-2607"},"institutions":[{"id":"https://openalex.org/I110200422","display_name":"Universidade Federal de Minas Gerais","ror":"https://ror.org/0176yjw32","country_code":"BR","type":"education","lineage":["https://openalex.org/I110200422"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["BR","DE"],"is_corresponding":false,"raw_author_name":"Adriano Barbosa-Silva","raw_affiliation_strings":["Laborat\u00f3rio de Biodados, Dep, Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Av, Ant\u00f4nio Carlos 6627, Belo Horizonte, MG, Brasil. barbosa@embl.de","Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Belo Horizonte, Brasil","European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Biodados, Dep, Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Av, Ant\u00f4nio Carlos 6627, Belo Horizonte, MG, Brasil. barbosa@embl.de","institution_ids":["https://openalex.org/I110200422"]},{"raw_affiliation_string":"Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Belo Horizonte, Brasil","institution_ids":[]},{"raw_affiliation_string":"European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany","institution_ids":["https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088017410","display_name":"Venkata Satagopam","orcid":"https://orcid.org/0000-0002-6532-5880"},"institutions":[{"id":"https://openalex.org/I1303691731","display_name":"European Molecular Biology Organization","ror":"https://ror.org/04wfr2810","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I1303691731"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Venkata P Satagopam","raw_affiliation_strings":["European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, 69117, Heidelberg, Germany","European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, 69117, Heidelberg, Germany","institution_ids":["https://openalex.org/I1303691731","https://openalex.org/I4210153543"]},{"raw_affiliation_string":"European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany","institution_ids":["https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079833473","display_name":"Reinhard Schneider","orcid":"https://orcid.org/0000-0002-8278-1618"},"institutions":[{"id":"https://openalex.org/I1303691731","display_name":"European Molecular Biology Organization","ror":"https://ror.org/04wfr2810","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I1303691731"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Reinhard Schneider","raw_affiliation_strings":["European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, 69117, Heidelberg, Germany","European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, 69117, Heidelberg, Germany","institution_ids":["https://openalex.org/I1303691731","https://openalex.org/I4210153543"]},{"raw_affiliation_string":"European Molecular Biology Laboratory, EMBL-Heidelberg, Meyerhofstr, Germany","institution_ids":["https://openalex.org/I4210153543"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059977137","display_name":"Jos\u00e9 Miguel Ortega","orcid":"https://orcid.org/0000-0003-1132-1910"},"institutions":[{"id":"https://openalex.org/I110200422","display_name":"Universidade Federal de Minas Gerais","ror":"https://ror.org/0176yjw32","country_code":"BR","type":"education","lineage":["https://openalex.org/I110200422"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"J Miguel Ortega","raw_affiliation_strings":["Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Av. Ant\u00f4nio Carlos 6627, Belo Horizonte, MG, Brasil","Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Belo Horizonte, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Av. Ant\u00f4nio Carlos 6627, Belo Horizonte, MG, Brasil","institution_ids":["https://openalex.org/I110200422"]},{"raw_affiliation_string":"Laborat\u00f3rio de Biodados, Dep. Bioqu\u00edmica e Imunologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Belo Horizonte, Brasil","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5059977137"],"corresponding_institution_ids":["https://openalex.org/I110200422"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.5199,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.64818833,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9","issue":"1","first_page":"141","last_page":"141"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.30570000410079956,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.30570000410079956,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.15410000085830688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.06759999692440033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/proteome","display_name":"Proteome","score":0.8981634378433228},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.7321774363517761},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.7145829200744629},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7024009227752686},{"id":"https://openalex.org/keywords/cognate","display_name":"Cognate","score":0.5870015025138855},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.47563958168029785},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.4503256380558014},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.44996848702430725},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4432760775089264},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.43632155656814575},{"id":"https://openalex.org/keywords/protein-sequencing","display_name":"Protein sequencing","score":0.42559006810188293},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4121352434158325},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.38709598779678345},{"id":"https://openalex.org/keywords/peptide-sequence","display_name":"Peptide sequence","score":0.3131142854690552},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.09825313091278076},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08642825484275818}],"concepts":[{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.8981634378433228},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.7321774363517761},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7145829200744629},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7024009227752686},{"id":"https://openalex.org/C2777392089","wikidata":"https://www.wikidata.org/wiki/Q690548","display_name":"Cognate","level":2,"score":0.5870015025138855},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47563958168029785},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.4503256380558014},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.44996848702430725},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4432760775089264},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.43632155656814575},{"id":"https://openalex.org/C10010492","wikidata":"https://www.wikidata.org/wiki/Q3142557","display_name":"Protein sequencing","level":4,"score":0.42559006810188293},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4121352434158325},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.38709598779678345},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.3131142854690552},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09825313091278076},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08642825484275818},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-9-141","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-141","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-141","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18321373","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18321373","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:f57cb2c313fc45dd800f1094d8c7cdfc","is_oa":true,"landing_page_url":"https://doaj.org/article/f57cb2c313fc45dd800f1094d8c7cdfc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 9, Iss 1, p 141 (2008)","raw_type":"article"},{"id":"pmh:oai:orbilu.uni.lu:10993/17191","is_oa":true,"landing_page_url":"http://orbilu.uni.lu/handle/10993/17191","pdf_url":null,"source":{"id":"https://openalex.org/S4306401815","display_name":"Open Repository and Bibliography (University of Luxembourg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I186903577","host_organization_name":"University of Luxembourg","host_organization_lineage":["https://openalex.org/I186903577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC bioinformatics, 9, 141. England (2008).","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2277401","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2277401","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-9-141","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-9-141","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-9-141","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320314023","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322980","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","ror":"https://ror.org/00nc55f03"},{"id":"https://openalex.org/F4320323809","display_name":"Minist\u00e9rio da Educa\u00e7\u00e3o","ror":"https://ror.org/04d0xx942"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2048777227.pdf","grobid_xml":"https://content.openalex.org/works/W2048777227.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1499898004","https://openalex.org/W1977027195","https://openalex.org/W2008856488","https://openalex.org/W2010562878","https://openalex.org/W2086194959","https://openalex.org/W2105106534","https://openalex.org/W2112884978","https://openalex.org/W2137464714","https://openalex.org/W2138578706","https://openalex.org/W2141935540","https://openalex.org/W2150452501","https://openalex.org/W2154139219","https://openalex.org/W2155606054","https://openalex.org/W2158714788","https://openalex.org/W2167188257","https://openalex.org/W2169929748"],"related_works":["https://openalex.org/W1982829397","https://openalex.org/W2347437365","https://openalex.org/W2106414650","https://openalex.org/W1999412725","https://openalex.org/W4390205769","https://openalex.org/W2124137418","https://openalex.org/W2391458050","https://openalex.org/W3022402204","https://openalex.org/W2086860678","https://openalex.org/W2114732768"],"abstract_inverted_index":{"BACKGROUND:":[0],"Modern":[1],"proteomes":[2],"evolved":[3],"by":[4,75,154],"modification":[5],"of":[6,23,42,51,80,87,165],"pre-existing":[7],"ones.":[8],"It":[9],"is":[10,167],"extremely":[11],"important":[12,88],"to":[13,36,105],"comparative":[14],"biology":[15],"that":[16,90,121,126,147],"related":[17,52],"proteins":[18,44,53,72,108,164],"be":[19,34],"identified":[20],"as":[21,149,151],"members":[22],"the":[24,40,46,76,84,127],"same":[25,47],"cognate":[26,81,107],"group,":[27],"since":[28],"a":[29,103],"characterized":[30],"putative":[31],"homolog":[32],"could":[33],"used":[35],"find":[37],"clues":[38],"about":[39],"function":[41],"uncharacterized":[43],"from":[45,57,109],"group.":[48],"Typically,":[49],"databases":[50,79],"focus":[54],"on":[55,138,162],"those":[56,152],"completely-sequenced":[58],"genomes.":[59],"Unfortunately,":[60],"relatively":[61],"few":[62],"organisms":[63,111],"have":[64,101],"had":[65],"their":[66],"genomes":[67],"fully":[68],"sequenced;":[69],"accordingly,":[70],"many":[71],"are":[73,91,130,148],"ignored":[74],"currently":[77],"available":[78],"proteins,":[82],"despite":[83],"high":[85],"amount":[86],"genes":[89],"functionally":[92],"described":[93],"only":[94,114,161],"for":[95,174],"these":[96],"incomplete":[97],"proteomes.":[98,176],"RESULTS:":[99],"We":[100,124],"developed":[102],"method":[104,144],"cluster":[106],"multiple":[110],"beginning":[112],"with":[113,120,133],"one":[115],"sequence,":[116],"through":[117],"connectivity":[118],"saturation":[119],"Seed":[122],"sequence.":[123],"show":[125],"generated":[128],"clusters":[129,159,173],"in":[131],"agreement":[132],"some":[134],"other":[135],"approaches":[136],"based":[137,160],"full":[139],"genome":[140],"comparison.":[141],"CONCLUSION:":[142],"The":[143],"produced":[145,153],"results":[146],"reliable":[150],"conventional":[155],"clustering":[156],"approaches.":[157],"Generating":[158],"individual":[163],"interest":[166],"less":[168],"time":[169],"consuming":[170],"than":[171],"generating":[172],"whole":[175]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}