{"id":"https://openalex.org/W2089062027","doi":"https://doi.org/10.1186/1471-2105-8-s2-s2","title":"Bayesian model-based inference of transcription factor activity","display_name":"Bayesian model-based inference of transcription factor activity","publication_year":2007,"publication_date":"2007-05-01","ids":{"openalex":"https://openalex.org/W2089062027","doi":"https://doi.org/10.1186/1471-2105-8-s2-s2","mag":"2089062027","pmid":"https://pubmed.ncbi.nlm.nih.gov/17493251"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-8-s2-s2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-s2-s2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-S2-S2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-S2-S2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060432668","display_name":"Simon Rogers","orcid":"https://orcid.org/0000-0003-3578-4477"},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Simon Rogers","raw_affiliation_strings":["Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK. srogers@dcs.gla.ac.uk","[Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK. srogers@dcs.gla.ac.uk","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"[Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK]","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081767603","display_name":"Raya Khanin","orcid":null},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Raya Khanin","raw_affiliation_strings":["Department of Statistics, University of Glasgow, Glasgow, UK","Department of Statistics University of Glasgow Glasgow UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"Department of Statistics University of Glasgow Glasgow UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045384249","display_name":"Mark Girolami","orcid":"https://orcid.org/0000-0003-3008-253X"},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark Girolami","raw_affiliation_strings":["Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK","[Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]},{"raw_affiliation_string":"[Bioinformatics Research Centre, Department of Computing Science, University of Glasgow, Glasgow, UK]","institution_ids":["https://openalex.org/I7882870"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060432668"],"corresponding_institution_ids":["https://openalex.org/I7882870"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":3.2723,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.92811345,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":"S2","first_page":"S2","last_page":"S2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.6744999885559082,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.6744999885559082,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.14710000157356262,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.09870000183582306,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6814570426940918},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.560222327709198},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5283818244934082},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5263829231262207},{"id":"https://openalex.org/keywords/bayesian-inference","display_name":"Bayesian inference","score":0.5158723592758179},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.48349907994270325},{"id":"https://openalex.org/keywords/replicate","display_name":"Replicate","score":0.47647830843925476},{"id":"https://openalex.org/keywords/transcription","display_name":"Transcription (linguistics)","score":0.4524118900299072},{"id":"https://openalex.org/keywords/linear-model","display_name":"Linear model","score":0.44403403997421265},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.43916332721710205},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.33333343267440796},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.32896214723587036},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2726839780807495},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2688351273536682},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.25684165954589844},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2525373697280884},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.21876341104507446},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.18496859073638916},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.16871508955955505}],"concepts":[{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6814570426940918},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.560222327709198},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5283818244934082},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5263829231262207},{"id":"https://openalex.org/C160234255","wikidata":"https://www.wikidata.org/wiki/Q812535","display_name":"Bayesian inference","level":3,"score":0.5158723592758179},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.48349907994270325},{"id":"https://openalex.org/C2781162219","wikidata":"https://www.wikidata.org/wiki/Q26250693","display_name":"Replicate","level":2,"score":0.47647830843925476},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4524118900299072},{"id":"https://openalex.org/C163175372","wikidata":"https://www.wikidata.org/wiki/Q3339222","display_name":"Linear model","level":2,"score":0.44403403997421265},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.43916332721710205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33333343267440796},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32896214723587036},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2726839780807495},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2688351273536682},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.25684165954589844},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2525373697280884},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21876341104507446},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18496859073638916},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.16871508955955505},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-8-s2-s2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-s2-s2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-S2-S2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17493251","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17493251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.gla.ac.uk:3763","is_oa":false,"landing_page_url":"http://eprints.gla.ac.uk/3763/1/Bayesian_model-based_inference_transcription.pdf","pdf_url":"http://eprints.gla.ac.uk/3763/1/Bayesian_model-based_inference_transcription.pdf","source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:pubmedcentral.nih.gov:1892071","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1892071","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1339709","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1339709/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In: (Proceedings) Workshop on Probabilistic Modeling and Machine Learning in Structural and Systems Biology. BMC (2007)","raw_type":"Proceedings paper"},{"id":"pmh:oai:generic.eprints.org:1185277","is_oa":false,"landing_page_url":"http://publications.eng.cam.ac.uk/1185277/","pdf_url":null,"source":{"id":"https://openalex.org/S4406922847","display_name":"Cambridge University Engineering Department Publications Database","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-8-s2-s2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-s2-s2","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-S2-S2","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16"}],"awards":[{"id":"https://openalex.org/G3347145179","display_name":null,"funder_award_id":"EP/C010620/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320320240","display_name":"Research Councils UK","ror":"https://ror.org/00dq2kk65"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2089062027.pdf","grobid_xml":"https://content.openalex.org/works/W2089062027.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1987144436","https://openalex.org/W1993009001","https://openalex.org/W1996264210","https://openalex.org/W2045656233","https://openalex.org/W2069645361","https://openalex.org/W2094414211","https://openalex.org/W2095622082","https://openalex.org/W2115662646","https://openalex.org/W2115990004","https://openalex.org/W2117521650","https://openalex.org/W2121150592","https://openalex.org/W2124584833","https://openalex.org/W2125904845","https://openalex.org/W2130416410","https://openalex.org/W2142182986","https://openalex.org/W2153624566","https://openalex.org/W2155465020","https://openalex.org/W2160064408","https://openalex.org/W2161443380","https://openalex.org/W2166106382","https://openalex.org/W2166303358","https://openalex.org/W2495204608","https://openalex.org/W4232383088","https://openalex.org/W4251644969"],"related_works":["https://openalex.org/W4254851101","https://openalex.org/W3171007296","https://openalex.org/W22115721","https://openalex.org/W2211931904","https://openalex.org/W2065444835","https://openalex.org/W2321234655","https://openalex.org/W2952773340","https://openalex.org/W2470062578","https://openalex.org/W2981861370","https://openalex.org/W2982204590"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1],"many":[2,43],"approaches":[3],"to":[4,27,50,91,107],"the":[5,15,18,22,33,37,54,60,63,67,81,93,117,146,165,171,180,193],"inference":[6,110,154],"and":[7,111,129,138,160],"modeling":[8],"of":[9,17,36,53,59,62,69,84,102,115,173,182,195],"regulatory":[10],"interactions":[11],"using":[12,183],"microarray":[13,131],"data,":[14],"expression":[16,68],"gene":[19,137],"coding":[20],"for":[21,32],"transcription":[23,55,64,94,103],"factor":[24,56,65,95],"is":[25,47,155,175],"considered":[26],"be":[28,120,143],"an":[29,113],"accurate":[30],"surrogate":[31],"true":[34],"activity":[35,61,96],"protein":[38],"it":[39],"produces.":[40],"There":[41],"are":[42],"instances":[44],"where":[45],"this":[46,158],"inaccurate":[48],"due":[49],"post-translational":[51],"modifications":[52],"protein.":[57],"Inference":[58],"from":[66,104],"its":[70],"targets":[71],"has":[72,161],"predominantly":[73],"involved":[74],"linear":[75,189],"models":[76],"that":[77,151],"do":[78],"not":[79],"reflect":[80],"nonlinear":[82,99],"nature":[83],"transcription.":[85],"We":[86,124,149,177],"extend":[87],"a":[88,184,188],"recent":[89],"approach":[90],"inferring":[92],"based":[97],"on":[98,127],"Michaelis-Menten":[100],"kinetics":[101],"maximum":[105,166],"likelihood":[106,167],"fully":[108],"Bayesian":[109,153],"give":[112],"example":[114],"how":[116,136],"model":[118,186],"can":[119,142],"further":[121],"developed.":[122],"RESULTS:":[123],"present":[125],"results":[126],"synthetic":[128],"real":[130],"data.":[132],"Additionally,":[133],"we":[134],"illustrate":[135],"replicate":[139],"specific":[140],"delays":[141],"incorporated":[144],"into":[145],"model.":[147],"CONCLUSION:":[148],"demonstrate":[150],"full":[152],"appropriate":[156],"in":[157,192],"application":[159],"several":[162],"benefits":[163,181],"over":[164,187],"approach,":[168],"especially":[169],"when":[170],"volume":[172],"data":[174],"limited.":[176],"also":[178],"show":[179],"non-linear":[185],"model,":[190],"particularly":[191],"case":[194],"repression.":[196]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}