{"id":"https://openalex.org/W2074859401","doi":"https://doi.org/10.1186/1471-2105-8-432","title":"Identifications of conserved 7-mers in 3'-UTRs and microRNAs in Drosophila","display_name":"Identifications of conserved 7-mers in 3'-UTRs and microRNAs in Drosophila","publication_year":2007,"publication_date":"2007-11-08","ids":{"openalex":"https://openalex.org/W2074859401","doi":"https://doi.org/10.1186/1471-2105-8-432","mag":"2074859401","pmid":"https://pubmed.ncbi.nlm.nih.gov/17996040"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-8-432","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-432","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-432","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-432","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012871103","display_name":"Jin Gu","orcid":"https://orcid.org/0000-0003-3968-8036"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Gu","raw_affiliation_strings":["Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com","[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100861299","display_name":"Hu Fu","orcid":null},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hu Fu","raw_affiliation_strings":["Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081242795","display_name":"Xuegong Zhang","orcid":"https://orcid.org/0000-0002-9684-5643"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuegong Zhang","raw_affiliation_strings":["Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033512723","display_name":"Yanda Li","orcid":"https://orcid.org/0000-0002-9439-202X"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanda Li","raw_affiliation_strings":["Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"[Bioinformatics Division, TNLIST, and Department of Automation, Tsinghua University, Beijing, China]","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033512723"],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.7975,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.77159105,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"8","issue":"1","first_page":"432","last_page":"432"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.8015999794006348,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.8015999794006348,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.03970000147819519,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.02290000021457672,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7254242897033691},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6555479168891907},{"id":"https://openalex.org/keywords/conserved-sequence","display_name":"Conserved sequence","score":0.6312747001647949},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6198551654815674},{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.5155184268951416},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5136551260948181},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4382012188434601},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.410370409488678},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.31161361932754517},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.20615485310554504},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.16072770953178406},{"id":"https://openalex.org/keywords/base-sequence","display_name":"Base sequence","score":0.10296997427940369},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.09000614285469055}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7254242897033691},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6555479168891907},{"id":"https://openalex.org/C199216141","wikidata":"https://www.wikidata.org/wiki/Q4995178","display_name":"Conserved sequence","level":4,"score":0.6312747001647949},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6198551654815674},{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.5155184268951416},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5136551260948181},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4382012188434601},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.410370409488678},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31161361932754517},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.20615485310554504},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16072770953178406},{"id":"https://openalex.org/C3017666073","wikidata":"https://www.wikidata.org/wiki/Q1764062","display_name":"Base sequence","level":3,"score":0.10296997427940369},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.09000614285469055}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017124","descriptor_name":"Conserved Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017124","descriptor_name":"Conserved Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017124","descriptor_name":"Conserved Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020029","descriptor_name":"Base Pairing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020029","descriptor_name":"Base Pairing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020029","descriptor_name":"Base Pairing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020413","descriptor_name":"3' Untranslated Regions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-8-432","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-432","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-432","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17996040","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17996040","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:87a24de5df8e4c4aa044d2062f5cc42d","is_oa":true,"landing_page_url":"https://doaj.org/article/87a24de5df8e4c4aa044d2062f5cc42d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 8, Iss 1, p 432 (2007)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:1832934","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2241842","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-8-432","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-432","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-432","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7599999904632568,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G2926295298","display_name":null,"funder_award_id":"2004CB518605","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2074859401.pdf","grobid_xml":"https://content.openalex.org/works/W2074859401.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1543796220","https://openalex.org/W1845151788","https://openalex.org/W1920564293","https://openalex.org/W1974736226","https://openalex.org/W1975981804","https://openalex.org/W1993799748","https://openalex.org/W1994955065","https://openalex.org/W2014946489","https://openalex.org/W2034500416","https://openalex.org/W2050869737","https://openalex.org/W2052483969","https://openalex.org/W2055309264","https://openalex.org/W2058682865","https://openalex.org/W2062290101","https://openalex.org/W2083381199","https://openalex.org/W2085442947","https://openalex.org/W2085592081","https://openalex.org/W2087892194","https://openalex.org/W2087966784","https://openalex.org/W2088930981","https://openalex.org/W2098044747","https://openalex.org/W2103017472","https://openalex.org/W2106144124","https://openalex.org/W2106423003","https://openalex.org/W2107268689","https://openalex.org/W2108491719","https://openalex.org/W2112192177","https://openalex.org/W2120456037","https://openalex.org/W2124268899","https://openalex.org/W2124756133","https://openalex.org/W2134591904","https://openalex.org/W2138043022","https://openalex.org/W2138910750","https://openalex.org/W2140446903","https://openalex.org/W2145191876","https://openalex.org/W2150770935","https://openalex.org/W2151922790","https://openalex.org/W2153428419","https://openalex.org/W2153635508","https://openalex.org/W2158266834","https://openalex.org/W2158561153","https://openalex.org/W2158714788","https://openalex.org/W2162165765","https://openalex.org/W2163199119","https://openalex.org/W2167557255","https://openalex.org/W2168783124","https://openalex.org/W2170677539","https://openalex.org/W2915985519","https://openalex.org/W4231824804","https://openalex.org/W6759401175"],"related_works":["https://openalex.org/W2487162673","https://openalex.org/W2942366970","https://openalex.org/W2793211469","https://openalex.org/W2949152769","https://openalex.org/W4372354731","https://openalex.org/W1692008701","https://openalex.org/W2597588799","https://openalex.org/W4360593462","https://openalex.org/W2562400057","https://openalex.org/W2809197864"],"abstract_inverted_index":{"BACKGROUND:":[0],"MicroRNAs":[1],"(miRNAs)":[2],"are":[3,55,61],"a":[4,68,103,152],"class":[5],"of":[6,32,80,90,132,148,173,227,236],"endogenous":[7],"regulatory":[8],"small":[9],"RNAs":[10],"which":[11,54,106],"play":[12],"an":[13],"important":[14],"role":[15],"in":[16,52,98,119,135,178,219,242,246,265],"posttranscriptional":[17],"regulations":[18],"by":[19,82,254],"targeting":[20],"mRNAs":[21],"for":[22,41,188],"cleavage":[23],"or":[24],"translational":[25],"repression.":[26],"The":[27],"base-pairing":[28,86],"between":[29,87,137],"the":[30,35,42,76,84,88,94,114,130,179,183,195,199,204,220,228,233,249,255],"5'-end":[31,89],"miRNA":[33,59,91,176,207,217,263],"and":[34,93,116,161,202,238],"target":[36],"mRNA":[37],"3'-UTRs":[38,136],"is":[39],"essential":[40],"miRNA:mRNA":[43],"recognition.":[44],"Recent":[45],"studies":[46],"show":[47],"that":[48],"many":[49],"seed":[50,96,168,244],"matches":[51,97,169,245],"3'-UTRs,":[53],"fully":[56],"complementary":[57,196],"to":[58,74,112,128,198,210],"5'-ends,":[60],"highly":[62],"conserved.":[63],"Based":[64],"on":[65],"these":[66,212],"features,":[67],"two-stage":[69],"strategy":[70],"can":[71],"be":[72],"implemented":[73],"achieve":[75],"de":[77],"novo":[78],"identification":[79],"miRNAs":[81],"requiring":[83],"complete":[85],"candidates":[92,218,264],"potential":[95],"3'-UTRs.":[99,120,247],"RESULTS:":[100],"We":[101,214],"presented":[102],"new":[104],"method,":[105],"combined":[107],"multiple":[108,250],"pairwise":[109,122,251],"conservation":[110,123,131,252],"information,":[111],"identify":[113],"frequently-occurred":[115],"conserved":[117,164,191],"7-mers":[118,134,165,201],"A":[121],"score":[124],"(PCS)":[125],"was":[126],"introduced":[127],"describe":[129],"all":[133],"any":[138],"two":[139],"Drosophila":[140],"species.":[141],"Using":[142],"PCSs":[143],"computed":[144],"from":[145,232],"6":[146,234],"pairs":[147,235],"flies,":[149],"we":[150,186,259],"developed":[151],"support":[153],"vector":[154],"machine":[155,256],"(SVM)":[156],"classifier":[157],"ensemble,":[158],"named":[159],"Cons-SVM":[160,224],"identified":[162,200,261],"689":[163],"including":[166],"63":[167],"covering":[170],"32":[171],"out":[172],"38":[174],"known":[175],"families":[177],"reference":[180],"dataset.":[181],"In":[182],"second":[184],"stage,":[185],"searched":[187],"90":[189],"nt":[190],"stem-loop":[192],"regions":[193],"containing":[194],"sequences":[197],"used":[203],"previously":[205],"published":[206],"prediction":[208],"software":[209],"analyze":[211],"stem-loops.":[213],"predicted":[215],"47":[216,262],"genome-wide":[221],"screen.":[222],"CONCLUSION:":[223],"takes":[225],"advantage":[226],"independent":[229],"evolutionary":[230],"information":[231,253],"flies":[237],"shows":[239],"high":[240],"sensitivity":[241],"identifying":[243],"Combining":[248],"learning":[257],"approach,":[258],"finally":[260],"D.":[266],"melanogaster.":[267]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}