{"id":"https://openalex.org/W2051262326","doi":"https://doi.org/10.1186/1471-2105-8-412","title":"Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data","display_name":"Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data","publication_year":2007,"publication_date":"2007-10-25","ids":{"openalex":"https://openalex.org/W2051262326","doi":"https://doi.org/10.1186/1471-2105-8-412","mag":"2051262326","pmid":"https://pubmed.ncbi.nlm.nih.gov/17961233"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-8-412","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-412","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-412","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-412","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051461953","display_name":"James J. Chen","orcid":"https://orcid.org/0000-0001-6967-6349"},"institutions":[{"id":"https://openalex.org/I1304557061","display_name":"National Center for Toxicological Research","ror":"https://ror.org/05jmhh281","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1304557061","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James J Chen","raw_affiliation_strings":["Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA. jamesj.chen@fda.hhs.gov","Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA. jamesj.chen@fda.hhs.gov","institution_ids":["https://openalex.org/I1304557061"]},{"raw_affiliation_string":"Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, USA","institution_ids":["https://openalex.org/I1304557061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049314583","display_name":"Huey\u2010Miin Hsueh","orcid":"https://orcid.org/0000-0003-0536-9440"},"institutions":[{"id":"https://openalex.org/I87354575","display_name":"National Chengchi University","ror":"https://ror.org/03rqk8h36","country_code":"TW","type":"education","lineage":["https://openalex.org/I87354575"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Huey-Miin Hsueh","raw_affiliation_strings":["Department of Statistics, National ChengChi University, Taipei, Taiwan","Department of Statistics, National Chengchi University, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, National ChengChi University, Taipei, Taiwan","institution_ids":["https://openalex.org/I87354575"]},{"raw_affiliation_string":"Department of Statistics, National Chengchi University, Taipei, Taiwan","institution_ids":["https://openalex.org/I87354575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038071704","display_name":"Robert R. Delongchamp","orcid":null},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert R Delongchamp","raw_affiliation_strings":["Department of Epidemiology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA","Department of Epidemiology, University of Arkansas for Medical Sciences, Little Rock, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA","institution_ids":["https://openalex.org/I79620101"]},{"raw_affiliation_string":"Department of Epidemiology, University of Arkansas for Medical Sciences, Little Rock, USA","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101872642","display_name":"Chien\u2010Ju Lin","orcid":"https://orcid.org/0000-0001-5224-3539"},"institutions":[{"id":"https://openalex.org/I1304557061","display_name":"National Center for Toxicological Research","ror":"https://ror.org/05jmhh281","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1304557061","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chien-Ju Lin","raw_affiliation_strings":["Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, 72079, USA","Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, 72079, USA","institution_ids":["https://openalex.org/I1304557061"]},{"raw_affiliation_string":"Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, USA","institution_ids":["https://openalex.org/I1304557061"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041574564","display_name":"Chen\u2010An Tsai","orcid":"https://orcid.org/0000-0002-7490-4331"},"institutions":[{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chen-An Tsai","raw_affiliation_strings":["Department of Public Health & Biostatistics Center, China Medical University, Taichung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health & Biostatistics Center, China Medical University, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5051461953"],"corresponding_institution_ids":["https://openalex.org/I1304557061"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":5.2846,"has_fulltext":true,"cited_by_count":151,"citation_normalized_percentile":{"value":0.96649914,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"412","last_page":"412"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.979200005531311,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.979200005531311,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/comparability","display_name":"Comparability","score":0.7606073617935181},{"id":"https://openalex.org/keywords/reproducibility","display_name":"Reproducibility","score":0.7501273155212402},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.6134771704673767},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.5770138502120972},{"id":"https://openalex.org/keywords/gene-chip-analysis","display_name":"Gene chip analysis","score":0.5249878168106079},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.5018126964569092},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4786902070045471},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44519904255867004},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.43616795539855957},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4229182004928589},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.346861869096756},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3453421890735626},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2948482930660248},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.2946310341358185},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.22719061374664307}],"concepts":[{"id":"https://openalex.org/C197947376","wikidata":"https://www.wikidata.org/wiki/Q5155608","display_name":"Comparability","level":2,"score":0.7606073617935181},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.7501273155212402},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6134771704673767},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.5770138502120972},{"id":"https://openalex.org/C24361400","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Gene chip analysis","level":5,"score":0.5249878168106079},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.5018126964569092},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4786902070045471},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44519904255867004},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.43616795539855957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4229182004928589},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.346861869096756},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3453421890735626},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2948482930660248},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2946310341358185},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.22719061374664307},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005189","descriptor_name":"False Positive Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005189","descriptor_name":"False Positive Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005189","descriptor_name":"False Positive Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015342","descriptor_name":"DNA Probes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015342","descriptor_name":"DNA Probes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015342","descriptor_name":"DNA Probes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D040081","descriptor_name":"Protein Array Analysis","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-8-412","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-412","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-412","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17961233","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17961233","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:1831742","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2204045","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:bc2054c55a064e6a9357ddd5374b6296","is_oa":false,"landing_page_url":"https://doaj.org/article/bc2054c55a064e6a9357ddd5374b6296","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 8, Iss 1, p 412 (2007)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-8-412","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-412","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-412","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2051262326.pdf","grobid_xml":"https://content.openalex.org/works/W2051262326.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1965781333","https://openalex.org/W1998913367","https://openalex.org/W2004088708","https://openalex.org/W2010637767","https://openalex.org/W2031205682","https://openalex.org/W2039057614","https://openalex.org/W2059288813","https://openalex.org/W2059428806","https://openalex.org/W2094801904","https://openalex.org/W2096037842","https://openalex.org/W2110065044","https://openalex.org/W2116146003","https://openalex.org/W2132561013","https://openalex.org/W2133206482","https://openalex.org/W2136746865","https://openalex.org/W2141009231","https://openalex.org/W2143364665","https://openalex.org/W2167098291","https://openalex.org/W2797120013","https://openalex.org/W3142307339","https://openalex.org/W4230792699","https://openalex.org/W4291732983"],"related_works":["https://openalex.org/W3004855132","https://openalex.org/W2767847608","https://openalex.org/W2361788533","https://openalex.org/W2051808073","https://openalex.org/W2015700328","https://openalex.org/W2138580185","https://openalex.org/W2911678823","https://openalex.org/W170658859","https://openalex.org/W4310366902","https://openalex.org/W2490137852"],"abstract_inverted_index":{"BACKGROUND:":[0],"Many":[1],"researchers":[2],"are":[3,179,277,298],"concerned":[4],"with":[5,92,223,235,332],"the":[6,18,35,45,61,64,83,90,93,102,108,135,148,152,175,192,198,208,280,294],"comparability":[7,36],"and":[8,34,49,82,104,107,137,166,227,286],"reliability":[9],"of":[10,17,47,52,63,89,95,110,119,129,157,183,188,191,210,296,307],"microarray":[11,53,80],"gene":[12,54,121,189,213,217,230],"expression":[13,55,297],"data.":[14],"Recent":[15],"completion":[16],"MicroArray":[19],"Quality":[20],"Control":[21],"(MAQC)":[22],"project":[23],"provides":[24],"a":[25,115,120,160,167,211,224,261,333],"unique":[26],"opportunity":[27],"to":[28,100,259],"assess":[29],"reproducibility":[30,106],"across":[31,37,197],"multiple":[32,38],"sites":[33,288],"platforms.":[39,154,200],"The":[40],"MAQC":[41,65],"analysis":[42,143,182,309],"presented":[43],"for":[44,67,117,311],"conclusion":[46],"inter-":[48,103],"intra-platform":[50,105],"comparability/reproducibility":[51],"measurements":[56],"is":[57,241,256,266,303,325],"inadequate.":[58],"We":[59,86,201],"evaluate":[60,101],"reproducibility/comparability":[62],"data":[66,308],"12901":[68],"common":[69],"genes":[70,112,158],"in":[71,134,147,163,170,279,313,339],"four":[72],"titration":[73],"samples":[74,193],"generated":[75],"from":[76],"five":[77,153,199],"high-density":[78],"one-color":[79],"platforms":[81,178,285],"TaqMan":[84],"technology.":[85],"discuss":[87],"some":[88],"problems":[91],"use":[94,312],"correlation":[96],"coefficient":[97],"as":[98,114,252],"metric":[99],"percent":[109,187],"overlapping":[111,229],"(POG)":[113],"measure":[116],"evaluation":[118],"selection":[122,244],"procedure":[123],"by":[124,283],"MAQC.":[125],"RESULTS:":[126],"A":[127,140,155,215],"total":[128],"293":[130],"arrays":[131],"were":[132],"used":[133],"intra-":[136],"inter-platform":[138],"analysis.":[139],"hierarchical":[141],"cluster":[142],"shows":[144,185],"distinct":[145],"differences":[146,278],"measured":[149,282],"intensities":[150,281],"among":[151],"number":[156],"show":[159,194],"small":[161],"fold-change":[162,169,330],"one":[164],"platform":[165],"large":[168],"another":[171],"platform,":[172,293],"even":[173],"though":[174],"correlations":[176],"between":[177],"high.":[180],"An":[181],"variance":[184],"thirty":[186],"expressions":[190],"inconsistent":[195],"patterns":[196,295],"illustrated":[202],"that":[203,264,275],"POG":[204,240,246,265],"does":[205],"not":[206],"reflect":[207],"accuracy":[209],"selected":[212],"list.":[214],"non-overlapping":[216],"can":[218,231,247],"be":[219,232],"truly":[220],"differentially":[221],"expressed":[222,234],"stringent":[225],"cut,":[226],"an":[228,242],"non-differentially":[233],"non-stringent":[236,334],"cutoff.":[237],"In":[238],"addition,":[239],"unusable":[243],"criterion.":[245],"increase":[248],"or":[249],"decrease":[250],"irregularly":[251],"cutoff":[253,262,331],"changes;":[254],"there":[255,276,302,324],"no":[257,318,326],"criterion":[258],"determine":[260],"so":[263],"optimized.":[267],"CONCLUSION:":[268],"Using":[269],"various":[270],"statistical":[271],"methods":[272,310],"we":[273],"demonstrate":[274],"different":[284,287],"within":[289],"platform.":[290],"Within":[291],"each":[292],"generally":[299],"consistent,":[300],"but":[301],"site-by-site":[304],"variability.":[305],"Evaluation":[306],"regulatory":[314],"decision":[315],"should":[316],"take":[317],"treatment":[319,327],"effect":[320],"into":[321],"consideration,":[322],"when":[323],"effect,":[328],"\"a":[329],"p-value":[335],"cutoff\"":[336],"could":[337],"result":[338],"100%":[340],"false":[341],"positive":[342],"error":[343],"selection.":[344]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":12}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}