{"id":"https://openalex.org/W2065879438","doi":"https://doi.org/10.1186/1471-2105-8-159","title":"A computational survey of candidate exonic splicing enhancer motifs in the model plant Arabidopsis thaliana","display_name":"A computational survey of candidate exonic splicing enhancer motifs in the model plant Arabidopsis thaliana","publication_year":2007,"publication_date":"2007-05-21","ids":{"openalex":"https://openalex.org/W2065879438","doi":"https://doi.org/10.1186/1471-2105-8-159","mag":"2065879438","pmid":"https://pubmed.ncbi.nlm.nih.gov/17517127"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-8-159","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-159","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-159","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-159","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009657521","display_name":"Mihaela Pertea","orcid":"https://orcid.org/0000-0003-0762-8637"},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mihaela Pertea","raw_affiliation_strings":["Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA. mpertea@umiacs.umd.edu","Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA. mpertea@umiacs.umd.edu","institution_ids":["https://openalex.org/I66946132"]},{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA","institution_ids":["https://openalex.org/I66946132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040594310","display_name":"Stephen M. Mount","orcid":"https://orcid.org/0000-0003-2748-8205"},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen M Mount","raw_affiliation_strings":["Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA","Dept. of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA","institution_ids":["https://openalex.org/I66946132"]},{"raw_affiliation_string":"Dept. of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA","institution_ids":["https://openalex.org/I66946132"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010384159","display_name":"Steven L. Salzberg","orcid":"https://orcid.org/0000-0002-8859-7432"},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven L Salzberg","raw_affiliation_strings":["Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, 20742, USA","institution_ids":["https://openalex.org/I66946132"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009657521"],"corresponding_institution_ids":["https://openalex.org/I66946132"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":2.1373,"has_fulltext":true,"cited_by_count":86,"citation_normalized_percentile":{"value":0.87083494,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"159","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/splice","display_name":"splice","score":0.8472009897232056},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.7160670161247253},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.652657687664032},{"id":"https://openalex.org/keywords/enhancer","display_name":"Enhancer","score":0.6338160634040833},{"id":"https://openalex.org/keywords/exon","display_name":"Exon","score":0.5439786911010742},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5357033610343933},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"Alternative splicing","score":0.5318692922592163},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.5264010429382324},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5133213400840759},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.47649091482162476},{"id":"https://openalex.org/keywords/ensembl","display_name":"Ensembl","score":0.4761812090873718},{"id":"https://openalex.org/keywords/exonic-splicing-enhancer","display_name":"Exonic splicing enhancer","score":0.4435434639453888},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.28299158811569214},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.1839050054550171},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.105502188205719},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.09716600179672241}],"concepts":[{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.8472009897232056},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.7160670161247253},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.652657687664032},{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.6338160634040833},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.5439786911010742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5357033610343933},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.5318692922592163},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.5264010429382324},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5133213400840759},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47649091482162476},{"id":"https://openalex.org/C141674004","wikidata":"https://www.wikidata.org/wiki/Q1344256","display_name":"Ensembl","level":5,"score":0.4761812090873718},{"id":"https://openalex.org/C42576000","wikidata":"https://www.wikidata.org/wiki/Q5420618","display_name":"Exonic splicing enhancer","level":5,"score":0.4435434639453888},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.28299158811569214},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.1839050054550171},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.105502188205719},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.09716600179672241},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-8-159","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-159","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-159","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17517127","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17517127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:d38016eaaddd4bf2a3eb3f1c5beb277a","is_oa":false,"landing_page_url":"https://doaj.org/article/d38016eaaddd4bf2a3eb3f1c5beb277a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 8, Iss 1, p 159 (2007)","raw_type":"article"},{"id":"pmh:oai:drum.lib.umd.edu:1903/28212","is_oa":false,"landing_page_url":"http://hdl.handle.net/1903/28212","pdf_url":null,"source":{"id":"https://openalex.org/S4306401518","display_name":"University Libraries (University of Maryland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66946132","host_organization_name":"University of Maryland, College Park","host_organization_lineage":["https://openalex.org/I66946132"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1892810","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1892810","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"doi:10.13016/4vjq-4wy9","is_oa":true,"landing_page_url":"https://doi.org/10.13016/4vjq-4wy9","pdf_url":null,"source":{"id":"https://openalex.org/S4306402644","display_name":"Digital Repository at the University of Maryland (University of Maryland College Park)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66946132","host_organization_name":"University of Maryland, College Park","host_organization_lineage":["https://openalex.org/I66946132"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1186/1471-2105-8-159","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-159","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-159","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G601011418","display_name":null,"funder_award_id":"R01-LM007938","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G7017850053","display_name":null,"funder_award_id":"R01 LM007938","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G7335511789","display_name":"Arabidopsis 2010:  Pre-mRNA Splicing Signals in Arabidopsis","funder_award_id":"0114792","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7910153056","display_name":null,"funder_award_id":"R01 LM006845","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2065879438.pdf","grobid_xml":"https://content.openalex.org/works/W2065879438.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W86712681","https://openalex.org/W1560479245","https://openalex.org/W1563462044","https://openalex.org/W1565521845","https://openalex.org/W1581360631","https://openalex.org/W2002360203","https://openalex.org/W2013235753","https://openalex.org/W2023648355","https://openalex.org/W2025607175","https://openalex.org/W2027699344","https://openalex.org/W2028587193","https://openalex.org/W2038921819","https://openalex.org/W2041998806","https://openalex.org/W2046095762","https://openalex.org/W2057880514","https://openalex.org/W2063318299","https://openalex.org/W2074330027","https://openalex.org/W2076050706","https://openalex.org/W2079384083","https://openalex.org/W2088440342","https://openalex.org/W2100899690","https://openalex.org/W2101835893","https://openalex.org/W2102337459","https://openalex.org/W2106356212","https://openalex.org/W2110400205","https://openalex.org/W2114858580","https://openalex.org/W2118301659","https://openalex.org/W2124010122","https://openalex.org/W2124288620","https://openalex.org/W2139212933","https://openalex.org/W2142419324","https://openalex.org/W2144921226","https://openalex.org/W2145295592","https://openalex.org/W2150298398","https://openalex.org/W2152323039","https://openalex.org/W2156909104","https://openalex.org/W2158266834","https://openalex.org/W2158714788","https://openalex.org/W2162111678","https://openalex.org/W2163716869","https://openalex.org/W2165876683","https://openalex.org/W2165954869","https://openalex.org/W2610493035","https://openalex.org/W2939704360","https://openalex.org/W3193477162","https://openalex.org/W4230674625"],"related_works":["https://openalex.org/W2001319824","https://openalex.org/W2067501355","https://openalex.org/W2159668471","https://openalex.org/W2008389025","https://openalex.org/W2136950317","https://openalex.org/W2155793948","https://openalex.org/W2038617558","https://openalex.org/W1538327476","https://openalex.org/W2093378391","https://openalex.org/W4389398524"],"abstract_inverted_index":{"BACKGROUND:":[0],"Algorithmic":[1],"approaches":[2],"to":[3,31,47,78,105,133],"splice":[4,37,54,90,122,136,151,172],"site":[5,55,123,152,173],"prediction":[6,174],"have":[7,28,41,101,146],"relied":[8],"mainly":[9],"on":[10],"the":[11,16,33,128,131,149,164,167],"consensus":[12],"patterns":[13],"found":[14],"at":[15],"boundaries":[17],"between":[18],"protein":[19],"coding":[20],"and":[21],"non-coding":[22],"regions.":[23],"However":[24],"exonic":[25,60,87],"splicing":[26,61],"enhancers":[27],"been":[29,102],"shown":[30,103],"enhance":[32],"utilization":[34],"of":[35,98,109,115,130,142,166],"nearby":[36],"sites.":[38],"RESULTS:":[39],"We":[40,145],"developed":[42],"a":[43,70,139],"new":[44],"computational":[45],"technique":[46],"identify":[48],"significantly":[49,126],"conserved":[50,80],"motifs":[51,81,100,118,169],"involved":[52],"in":[53,66,86,92,138],"regulation.":[56],"First,":[57],"84":[58],"putative":[59],"enhancer":[62],"hexamers":[63,85],"are":[64],"identified":[65],"Arabidopsis":[67],"thaliana.":[68],"Then":[69],"Gibbs":[71],"sampling":[72],"program":[73],"called":[74],"ELPH":[75],"was":[76],"used":[77],"locate":[79],"represented":[82],"by":[83],"these":[84,99],"regions":[88],"near":[89],"sites":[91,137],"confirmed":[93,143],"genes.":[94,144],"Oligomers":[95],"containing":[96],"35":[97],"experimentally":[104],"induce":[106],"significant":[107],"inclusion":[108],"A.":[110],"thaliana":[111],"exons.":[112],"Second,":[113],"integration":[114],"our":[116],"regulatory":[117],"into":[119],"two":[120],"different":[121],"recognition":[124,153],"programs":[125],"improved":[127,150],"ability":[129],"software":[132],"correctly":[134],"predict":[135],"large":[140],"database":[141],"released":[147],"GeneSplicerESE,":[148],"code,":[154],"as":[155],"open":[156],"source":[157],"software.":[158],"CONCLUSION:":[159],"Our":[160],"results":[161],"show":[162],"that":[163],"use":[165],"ESE":[168],"consistently":[170],"improves":[171],"accuracy.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}