{"id":"https://openalex.org/W1739940154","doi":"https://doi.org/10.1186/1471-2105-8-14","title":"Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation","display_name":"Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation","publication_year":2007,"publication_date":"2007-01-18","ids":{"openalex":"https://openalex.org/W1739940154","doi":"https://doi.org/10.1186/1471-2105-8-14","mag":"1739940154","pmid":"https://pubmed.ncbi.nlm.nih.gov/17233900"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-8-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-14","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-14","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-14","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052006543","display_name":"Rob Jelier","orcid":"https://orcid.org/0000-0002-6395-1407"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rob Jelier","raw_affiliation_strings":["Department of Medical Informatics, Erasmus MC--University Medical Center, Rotterdam, The Netherlands. r.jelier@erasmusmc.nl","Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC--University Medical Center, Rotterdam, The Netherlands. r.jelier@erasmusmc.nl","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034635531","display_name":"Guido Jenster","orcid":"https://orcid.org/0000-0002-8658-2552"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Guido Jenster","raw_affiliation_strings":["Department of Urology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","Department of Urology Erasmus MC, University Medical Center Rotterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Urology Erasmus MC, University Medical Center Rotterdam The Netherlands","institution_ids":["https://openalex.org/I913958620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109058788","display_name":"Lambert C. J. Dorssers","orcid":null},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Lambert CJ Dorssers","raw_affiliation_strings":["Department of Pathology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands and","Department of Pathology, Erasmus MC - University Medical Center Rotterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands and","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Pathology, Erasmus MC - University Medical Center Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052765516","display_name":"Bas J. Wouters","orcid":null},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bas J Wouters","raw_affiliation_strings":["Department of Hematology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands","Department of Hematology, Erasmus MC, University Medical Center Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Hematology, Erasmus MC, University Medical Center Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024589017","display_name":"Peter J.M. Hendriksen","orcid":"https://orcid.org/0000-0002-0951-3270"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Peter JM Hendriksen","raw_affiliation_strings":["Department of Urology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","Department of Urology Erasmus MC, University Medical Center Rotterdam The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Urology Erasmus MC, University Medical Center Rotterdam The Netherlands","institution_ids":["https://openalex.org/I913958620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070745825","display_name":"Barend Mons","orcid":null},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Barend Mons","raw_affiliation_strings":["Department of Medical Informatics, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064638868","display_name":"Ruud Delwel","orcid":null},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ruud Delwel","raw_affiliation_strings":["Department of Hematology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands","Department of Hematology, Erasmus MC, University Medical Center Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Erasmus MC -University Medical Center, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Hematology, Erasmus MC, University Medical Center Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005077862","display_name":"Jan A. Kors","orcid":"https://orcid.org/0000-0002-4929-026X"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jan A Kors","raw_affiliation_strings":["Department of Medical Informatics, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC -University Medical Center, Rotterdam, The Netherlands,","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":4.1488,"has_fulltext":true,"cited_by_count":51,"citation_normalized_percentile":{"value":0.94868766,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":"1","first_page":"14","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.032600000500679016,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.6774790287017822},{"id":"https://openalex.org/keywords/myeloid-leukemia","display_name":"Myeloid leukemia","score":0.6738052368164062},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5926755666732788},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5810655951499939},{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"Androgen receptor","score":0.5403978228569031},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.5198862552642822},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.510576605796814},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4934757947921753},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.46531108021736145},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.452256441116333},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.425863116979599},{"id":"https://openalex.org/keywords/leukemia","display_name":"Leukemia","score":0.41586410999298096},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.39780932664871216},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3389400839805603},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.3129326105117798},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2928296625614166},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.2648653984069824}],"concepts":[{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6774790287017822},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.6738052368164062},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5926755666732788},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5810655951499939},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.5403978228569031},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.5198862552642822},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.510576605796814},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4934757947921753},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.46531108021736145},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.452256441116333},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.425863116979599},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.41586410999298096},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.39780932664871216},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3389400839805603},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3129326105117798},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2928296625614166},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.2648653984069824},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1186/1471-2105-8-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-14","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-14","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17233900","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17233900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/a186991e-327e-46b4-a003-a0d8dbc7379b","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/a186991e-327e-46b4-a003-a0d8dbc7379b","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jelier, R, Jenster, G, Dorssers, L C, Wouters, B J, Hendriksen, P J M, Mons, B, Delwel, R & Kors, J A 2007, 'Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation.', BMC Bioinformatics, vol. 18, no. 8, pp. 14. https://doi.org/10.1186/1471-2105-8-14","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.eur.nl:openaire_cris_publications/16e21436-654b-4eec-961f-ed69ecc921da","is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/16e21436-654b-4eec-961f-ed69ecc921da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jelier, R, Jenster, G, Dorssers, L, Wouters, B, Hendriksen, PJM, Mons, B, Delwel, R & Kors, J 2007, 'Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation', BMC Bioinformatics, vol. 8. https://doi.org/10.1186/1471-2105-8-14","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:repub.eur.nl:36938","is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/36938","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"B M C Bioinformatics, 8","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:afd3f3661a134f938b1be3730736075a","is_oa":true,"landing_page_url":"https://doaj.org/article/afd3f3661a134f938b1be3730736075a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 8, Iss 1, p 14 (2007)","raw_type":"article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:123456789/625590","is_oa":true,"landing_page_url":"http://www.biomedcentral.com/1471-2105/8/14","pdf_url":null,"source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, vol. 8, Art.No. 14","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1784107","is_oa":true,"landing_page_url":"http://doi.org/10.1186/1471-2105-8-14","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:repub.eur.nl:36938","is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/36938","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"B M C Bioinformatics vol. 8","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-8-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-8-14","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-8-14","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Quality Education","score":0.44999998807907104,"id":"https://metadata.un.org/sdg/4"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322777","display_name":"KWF Kankerbestrijding","ror":"https://ror.org/0368jnd28"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1739940154.pdf","grobid_xml":"https://content.openalex.org/works/W1739940154.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W333749564","https://openalex.org/W1209284060","https://openalex.org/W1523095068","https://openalex.org/W1790194223","https://openalex.org/W1829379010","https://openalex.org/W1833785989","https://openalex.org/W1970405223","https://openalex.org/W1976927254","https://openalex.org/W1985442806","https://openalex.org/W1987146951","https://openalex.org/W1990748933","https://openalex.org/W1991747826","https://openalex.org/W2015954361","https://openalex.org/W2027199606","https://openalex.org/W2037345530","https://openalex.org/W2061572799","https://openalex.org/W2069031138","https://openalex.org/W2079982743","https://openalex.org/W2096369586","https://openalex.org/W2108491719","https://openalex.org/W2110502951","https://openalex.org/W2115159360","https://openalex.org/W2116156361","https://openalex.org/W2116780029","https://openalex.org/W2123248953","https://openalex.org/W2127499728","https://openalex.org/W2135063148","https://openalex.org/W2136992683","https://openalex.org/W2137051799","https://openalex.org/W2142063400","https://openalex.org/W2145394518","https://openalex.org/W2149942697","https://openalex.org/W2152698860","https://openalex.org/W2155686896","https://openalex.org/W2157569416","https://openalex.org/W2157825442","https://openalex.org/W2158505321","https://openalex.org/W2159203162","https://openalex.org/W2159482845","https://openalex.org/W2159583324","https://openalex.org/W2160238006","https://openalex.org/W2163596704","https://openalex.org/W2168905447","https://openalex.org/W2398956536","https://openalex.org/W4237140380","https://openalex.org/W4240689716","https://openalex.org/W4241607140","https://openalex.org/W4294216483","https://openalex.org/W4301284037"],"related_works":["https://openalex.org/W1996185163","https://openalex.org/W170658859","https://openalex.org/W2081127504","https://openalex.org/W1483316219","https://openalex.org/W4310366902","https://openalex.org/W3023720143","https://openalex.org/W2183420549","https://openalex.org/W2107563406","https://openalex.org/W2081507994","https://openalex.org/W1972696957"],"abstract_inverted_index":{"BACKGROUND:":[0],"High-throughput":[1],"experiments,":[2],"such":[3],"as":[4],"with":[5,198],"DNA":[6,132,265],"microarrays,":[7],"typically":[8],"result":[9],"in":[10,65,71,80,109,137,215,235,243,275],"hundreds":[11],"of":[12,24,42,56,161,164,172,177,191,207,246],"genes":[13,43,99,210],"potentially":[14],"relevant":[15],"to":[16,35,77,96,125,194,263],"the":[17,22,63,67,81,128,138,142,158,174,178,223,231,244,276],"process":[18],"under":[19],"study,":[20],"rendering":[21],"interpretation":[23],"these":[25,192,236],"experiments":[26,134],"problematic.":[27],"Here,":[28],"we":[29,187,225],"propose":[30],"and":[31,44,100,141,249,272],"evaluate":[32],"an":[33,189],"approach":[34],"find":[36,97],"functional":[37],"associations":[38],"between":[39],"large":[40],"numbers":[41],"other":[45,101,199],"biomedical":[46],"concepts":[47,58],"from":[48,130],"free-text":[49],"literature.":[50,72,277],"For":[51,169],"each":[52,78],"gene,":[53],"a":[54,75,85,118,153,162,216,228,280],"profile":[55,82,155],"related":[57,98],"is":[59,69,181],"constructed":[60],"that":[61,156],"summarizes":[62],"context":[64],"which":[66,196],"gene":[68],"mentioned":[70],"We":[73,112,278],"assign":[74],"weight":[76],"concept":[79,90],"based":[83,268],"on":[84,117,222,269],"likelihood":[86],"ratio":[87],"measure.":[88],"Gene":[89],"profiles":[91],"can":[92,260],"then":[93],"be":[94,126,261],"clustered":[95],"concepts.":[102],"RESULTS:":[103],"The":[104,149,202],"experimental":[105,200],"validation":[106],"was":[107,152],"done":[108],"two":[110,131],"steps.":[111],"first":[113,150],"applied":[114],"our":[115,185],"method":[116,259],"controlled":[119],"test":[120],"set.":[121],"After":[122],"this":[123,170,287],"proved":[124],"successful":[127],"datasets":[129,267],"microarray":[133,266],"were":[135,144],"analyzed":[136],"same":[139],"way":[140],"results":[143],"evaluated":[145],"by":[146],"domain":[147],"experts.":[148],"dataset":[151],"gene-expression":[154],"characterizes":[157],"cancer":[159,179,218],"cells":[160,180,193],"group":[163,171],"acute":[165],"myeloid":[166],"leukemia":[167],"patients.":[168],"patients":[173],"biological":[175,232],"background":[176],"largely":[182],"unknown.":[183],"Using":[184],"methodology":[186],"found":[188],"association":[190],"monocytes,":[195],"agreed":[197],"evidence.":[201],"second":[203],"data":[204],"set":[205],"consisted":[206],"differentially":[208],"expressed":[209],"following":[211],"androgen":[212],"receptor":[213],"stimulation":[214],"prostate":[217],"cell":[219],"line.":[220],"Based":[221],"analysis":[224],"put":[226],"forward":[227],"hypothesis":[229],"about":[230],"processes":[233],"induced":[234],"studied":[237],"cells:":[238],"secretory":[239],"lysosomes":[240],"are":[241,254],"involved":[242],"production":[245],"prostatic":[247],"fluid":[248],"their":[250],"development":[251],"and/or":[252],"secretion":[253],"androgen-regulated":[255],"processes.":[256],"CONCLUSION:":[257],"Our":[258],"used":[262],"analyze":[264],"information":[270],"explicitly":[271],"implicitly":[273],"available":[274,282],"provide":[279],"publicly":[281],"tool,":[283],"dubbed":[284],"Anni,":[285],"for":[286],"purpose.":[288]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}