{"id":"https://openalex.org/W1524671351","doi":"https://doi.org/10.1186/1471-2105-7-467","title":"Goulphar: rapid access and expertise for standard two-color microarray normalization methods","display_name":"Goulphar: rapid access and expertise for standard two-color microarray normalization methods","publication_year":2006,"publication_date":"2006-10-23","ids":{"openalex":"https://openalex.org/W1524671351","doi":"https://doi.org/10.1186/1471-2105-7-467","mag":"1524671351","pmid":"https://pubmed.ncbi.nlm.nih.gov/17059595"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078001342","display_name":"Sophie Lemoine","orcid":"https://orcid.org/0000-0003-0975-5365"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Lemoine","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, Ecole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230 Paris cedex05, France. slemoine@biologie.ens.fr","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, Ecole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230 Paris cedex05, France. slemoine@biologie.ens.fr","institution_ids":["https://openalex.org/I29607241","https://openalex.org/I4210129409"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036045152","display_name":"Florence Combes","orcid":"https://orcid.org/0000-0001-7384-4587"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florence Combes","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047327833","display_name":"Nicolas Servant","orcid":"https://orcid.org/0000-0003-1678-7410"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Servant","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052835091","display_name":"St\u00e9phane Le Crom","orcid":"https://orcid.org/0000-0002-0534-7797"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210103330","display_name":"\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/01dp7jr64","country_code":"BI","type":"education","lineage":["https://openalex.org/I4210103330"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["BI","FR"],"is_corresponding":true,"raw_author_name":"St\u00e9phane Le Crom","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","INSERM U784, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","G\u00e9n\u00e9tique mol\u00e9culaire du d\u00e9veloppement (Ecole Normale Superieure 46, Rue D'Ulm 75230 Paris Cedex 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"INSERM U784, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I29607241","https://openalex.org/I4210103330"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique mol\u00e9culaire du d\u00e9veloppement (Ecole Normale Superieure 46, Rue D'Ulm 75230 Paris Cedex 05 - France)","institution_ids":["https://openalex.org/I29607241"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5052835091"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I29607241","https://openalex.org/I4210103330","https://openalex.org/I4210129409"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.6363,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.81339023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"467","last_page":"467"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9501000046730042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9501000046730042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13398","display_name":"Data Analysis with R","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.9769894480705261},{"id":"https://openalex.org/keywords/normalization","display_name":"Normalization (sociology)","score":0.8768234252929688},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7579286098480225},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5400806665420532},{"id":"https://openalex.org/keywords/graphics","display_name":"Graphics","score":0.5208990573883057},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5152900218963623},{"id":"https://openalex.org/keywords/raw-data","display_name":"Raw data","score":0.4737696945667267},{"id":"https://openalex.org/keywords/data-manipulation-language","display_name":"Data manipulation language","score":0.4175604581832886},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.16270729899406433},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.10947582125663757}],"concepts":[{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.9769894480705261},{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.8768234252929688},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7579286098480225},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5400806665420532},{"id":"https://openalex.org/C21442007","wikidata":"https://www.wikidata.org/wiki/Q1027879","display_name":"Graphics","level":2,"score":0.5208990573883057},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5152900218963623},{"id":"https://openalex.org/C132964779","wikidata":"https://www.wikidata.org/wiki/Q2110223","display_name":"Raw data","level":2,"score":0.4737696945667267},{"id":"https://openalex.org/C56288433","wikidata":"https://www.wikidata.org/wiki/Q58673","display_name":"Data manipulation language","level":2,"score":0.4175604581832886},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.16270729899406433},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.10947582125663757},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17059595","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17059595","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:HAL:hal-03842496v1","is_oa":false,"landing_page_url":"https://hal.science/hal-03842496","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2006, 7 (1), pp.467. ⟨10.1186/1471-2105-7-467⟩","raw_type":"Journal articles"},{"id":"pmh:oai:HAL:inserm-00122139v1","is_oa":true,"landing_page_url":"https://inserm.hal.science/inserm-00122139","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2006, 7, pp.467. ⟨10.1186/1471-2105-7-467⟩","raw_type":"Journal articles"},{"id":"pmh:oai:doaj.org/article:eb237e73a9cd44c48add7454389e76e9","is_oa":false,"landing_page_url":"https://doaj.org/article/eb237e73a9cd44c48add7454389e76e9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 7, Iss 1, p 467 (2006)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1626094","is_oa":true,"landing_page_url":"http://doi.org/10.1186/1471-2105-7-467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1524671351.pdf","grobid_xml":"https://content.openalex.org/works/W1524671351.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1789015559","https://openalex.org/W1970824927","https://openalex.org/W1987400169","https://openalex.org/W1991320896","https://openalex.org/W2013444425","https://openalex.org/W2046740637","https://openalex.org/W2096037842","https://openalex.org/W2100668965","https://openalex.org/W2101163066","https://openalex.org/W2101641305","https://openalex.org/W2104292638","https://openalex.org/W2106745617","https://openalex.org/W2107989651","https://openalex.org/W2141009231","https://openalex.org/W2152147743","https://openalex.org/W2160697532","https://openalex.org/W2163289463","https://openalex.org/W2171804472"],"related_works":["https://openalex.org/W2135678793","https://openalex.org/W2109288169","https://openalex.org/W2951444558","https://openalex.org/W2914550539","https://openalex.org/W1594712091","https://openalex.org/W4235296672","https://openalex.org/W1524671351","https://openalex.org/W111500385","https://openalex.org/W4382068336","https://openalex.org/W1984036613"],"abstract_inverted_index":{"BACKGROUND:":[0],"Raw":[1],"data":[2,10,16,79],"normalization":[3,21,80,165,171],"is":[4,33],"a":[5,63,70,138,186],"critical":[6],"step":[7],"in":[8,27,66,107,122,185],"microarray":[9],"analysis":[11,93,203],"because":[12],"it":[13,32],"directly":[14],"affects":[15],"interpretation.":[17],"Most":[18],"of":[19,45,73,78,89,99,141,199,210],"the":[20,28,38,43,87,97,111,151,160,164,170,175,197,200,211],"methods":[22],"currently":[23],"used":[24],"are":[25,56,183,224],"included":[26],"R/BioConductor":[29,201],"packages":[30,124],"but":[31],"often":[34],"difficult":[35,57],"to":[36,58,75,128,162,174,196],"identify":[37],"most":[39],"appropriate":[40],"method.":[41],"Furthermore,":[42],"use":[44],"R":[46,67,92,100,112],"commands":[47],"for":[48,81,130,146,220],"functions":[49,94,120],"and":[50,76,91,95,108,114,118,126,133,143,167,180,208,217],"graphics":[51],"can":[52],"introduce":[53],"mistakes":[54],"that":[55,68],"trace.":[59],"We":[60],"present":[61],"here":[62],"script":[64,85,222],"written":[65],"provides":[69,137,192],"flexible":[71],"means":[72],"access":[74,195],"monitoring":[77],"two-color":[82],"microarrays.":[83],"This":[84],"combines":[86,117],"power":[88,198],"BioConductor":[90,123],"reduces":[96],"amount":[98],"programming":[101],"required.":[102],"RESULTS:":[103],"Goulphar":[104,136,191],"was":[105],"developed":[106],"runs":[109],"using":[110],"language":[113],"environment.":[115],"It":[116,154],"extends":[119],"found":[121],"(limma":[125],"marray)":[127],"correct":[129],"dye":[131],"biases":[132],"spatial":[134],"artifacts.":[135],"wide":[139],"range":[140],"optional":[142],"customizable":[144],"filters":[145],"excluding":[147],"incorrect":[148],"signals":[149],"during":[150],"pre-processing":[152],"step.":[153],"displays":[155],"informative":[156],"output":[157],"plots,":[158],"enabling":[159],"user":[161],"monitor":[163],"process,":[166],"helps":[168],"adapt":[169],"method":[172],"appropriately":[173],"data.":[176],"All":[177],"these":[178],"analyses":[179],"graphical":[181],"outputs":[182],"presented":[184],"single":[187],"PDF":[188],"report.":[189],"CONCLUSION:":[190],"simple,":[193],"rapid":[194],"statistical":[202],"packages,":[204],"with":[205],"precise":[206],"control":[207],"visualization":[209],"results":[212],"obtained.":[213],"Complete":[214],"documentation,":[215],"examples":[216],"online":[218],"forms":[219],"setting":[221],"parameters":[223],"available":[225],"from":[226],"http://transcriptome.ens.fr/goulphar/.":[227]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}