{"id":"https://openalex.org/W1524671351","doi":"https://doi.org/10.1186/1471-2105-7-467","title":"Goulphar: rapid access and expertise for standard two-color microarray normalization methods","display_name":"Goulphar: rapid access and expertise for standard two-color microarray normalization methods","publication_year":2006,"publication_date":"2006-10-23","ids":{"openalex":"https://openalex.org/W1524671351","doi":"https://doi.org/10.1186/1471-2105-7-467","mag":"1524671351","pmid":"https://pubmed.ncbi.nlm.nih.gov/17059595"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078001342","display_name":"Sophie Lemoine","orcid":"https://orcid.org/0000-0003-0975-5365"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Lemoine","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, Ecole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230 Paris cedex05, France. slemoine@biologie.ens.fr","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, Ecole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230 Paris cedex05, France. slemoine@biologie.ens.fr","institution_ids":["https://openalex.org/I29607241","https://openalex.org/I4210129409"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036045152","display_name":"Florence Combes","orcid":"https://orcid.org/0000-0001-7384-4587"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florence Combes","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047327833","display_name":"Nicolas Servant","orcid":"https://orcid.org/0000-0003-1678-7410"},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Servant","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052835091","display_name":"St\u00e9phane Le Crom","orcid":"https://orcid.org/0000-0002-0534-7797"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210129409","display_name":"Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/03mxktp47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I4210096427","https://openalex.org/I4210129409"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"St\u00e9phane Le Crom","raw_affiliation_strings":["IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","INSERM U784, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","G\u00e9n\u00e9tique mol\u00e9culaire du d\u00e9veloppement (Ecole Normale Superieure 46, Rue D'Ulm 75230 Paris Cedex 05 - France)","IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFR36, Plate-forme Transcriptome, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"INSERM U784, \u00c9cole Normale Sup\u00e9rieure, 46 rue d'Ulm, 75230, Paris cedex05, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I29607241"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique mol\u00e9culaire du d\u00e9veloppement (Ecole Normale Superieure 46, Rue D'Ulm 75230 Paris Cedex 05 - France)","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"IBENS - Institut de biologie de l'Ecole Normale Sup\u00e9rieure (46 Rue d'Ulm 75230 PARIS CEDEX 05 - France)","institution_ids":["https://openalex.org/I4210129409"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5052835091"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I29607241","https://openalex.org/I4210129409"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.5264,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.79946281,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"467","last_page":"467"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9501000046730042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9501000046730042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13398","display_name":"Data Analysis with R","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.9769894480705261},{"id":"https://openalex.org/keywords/normalization","display_name":"Normalization (sociology)","score":0.8768234252929688},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7579286098480225},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5400806665420532},{"id":"https://openalex.org/keywords/graphics","display_name":"Graphics","score":0.5208990573883057},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5152900218963623},{"id":"https://openalex.org/keywords/raw-data","display_name":"Raw data","score":0.4737696945667267},{"id":"https://openalex.org/keywords/data-manipulation-language","display_name":"Data manipulation language","score":0.4175604581832886},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.16270729899406433},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.10947582125663757}],"concepts":[{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.9769894480705261},{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.8768234252929688},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7579286098480225},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5400806665420532},{"id":"https://openalex.org/C21442007","wikidata":"https://www.wikidata.org/wiki/Q1027879","display_name":"Graphics","level":2,"score":0.5208990573883057},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5152900218963623},{"id":"https://openalex.org/C132964779","wikidata":"https://www.wikidata.org/wiki/Q2110223","display_name":"Raw data","level":2,"score":0.4737696945667267},{"id":"https://openalex.org/C56288433","wikidata":"https://www.wikidata.org/wiki/Q58673","display_name":"Data manipulation language","level":2,"score":0.4175604581832886},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.16270729899406433},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.10947582125663757},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005103","descriptor_name":"Expert Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D036641","descriptor_name":"Microscopy, Fluorescence, Multiphoton","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17059595","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17059595","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:HAL:hal-03842496v1","is_oa":false,"landing_page_url":"https://hal.science/hal-03842496","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2006, 7 (1), pp.467. ⟨10.1186/1471-2105-7-467⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:inserm-00122139v1","is_oa":false,"landing_page_url":"https://inserm.hal.science/inserm-00122139","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2006, 7, pp.467. ⟨10.1186/1471-2105-7-467⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:eb237e73a9cd44c48add7454389e76e9","is_oa":false,"landing_page_url":"https://doaj.org/article/eb237e73a9cd44c48add7454389e76e9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 7, Iss 1, p 467 (2006)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1626094","is_oa":true,"landing_page_url":"http://doi.org/10.1186/1471-2105-7-467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-7-467","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-467","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-467","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1524671351.pdf","grobid_xml":"https://content.openalex.org/works/W1524671351.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1789015559","https://openalex.org/W1970824927","https://openalex.org/W1987400169","https://openalex.org/W1991320896","https://openalex.org/W2013444425","https://openalex.org/W2046740637","https://openalex.org/W2096037842","https://openalex.org/W2100668965","https://openalex.org/W2101163066","https://openalex.org/W2101641305","https://openalex.org/W2104292638","https://openalex.org/W2106745617","https://openalex.org/W2107989651","https://openalex.org/W2141009231","https://openalex.org/W2152147743","https://openalex.org/W2160697532","https://openalex.org/W2163289463","https://openalex.org/W2171804472"],"related_works":["https://openalex.org/W2135678793","https://openalex.org/W2109288169","https://openalex.org/W2951444558","https://openalex.org/W2914550539","https://openalex.org/W1594712091","https://openalex.org/W4235296672","https://openalex.org/W1524671351","https://openalex.org/W111500385","https://openalex.org/W4382068336","https://openalex.org/W1984036613"],"abstract_inverted_index":{"BACKGROUND:":[0],"Raw":[1],"data":[2,10,16,79],"normalization":[3,21,80,165,171],"is":[4,33],"a":[5,63,70,138,186],"critical":[6],"step":[7],"in":[8,27,66,107,122,185],"microarray":[9],"analysis":[11,93,203],"because":[12],"it":[13,32],"directly":[14],"affects":[15],"interpretation.":[17],"Most":[18],"of":[19,45,73,78,89,99,141,199,210],"the":[20,28,38,43,87,97,111,151,160,164,170,175,197,200,211],"methods":[22],"currently":[23],"used":[24],"are":[25,56,183,224],"included":[26],"R/BioConductor":[29,201],"packages":[30,124],"but":[31],"often":[34],"difficult":[35,57],"to":[36,58,75,128,162,174,196],"identify":[37],"most":[39],"appropriate":[40],"method.":[41],"Furthermore,":[42],"use":[44],"R":[46,67,92,100,112],"commands":[47],"for":[48,81,130,146,220],"functions":[49,94,120],"and":[50,76,91,95,108,114,118,126,133,143,167,180,208,217],"graphics":[51],"can":[52],"introduce":[53],"mistakes":[54],"that":[55,68],"trace.":[59],"We":[60],"present":[61],"here":[62],"script":[64,85,222],"written":[65],"provides":[69,137,192],"flexible":[71],"means":[72],"access":[74,195],"monitoring":[77],"two-color":[82],"microarrays.":[83],"This":[84],"combines":[86,117],"power":[88,198],"BioConductor":[90,123],"reduces":[96],"amount":[98],"programming":[101],"required.":[102],"RESULTS:":[103],"Goulphar":[104,136,191],"was":[105],"developed":[106],"runs":[109],"using":[110],"language":[113],"environment.":[115],"It":[116,154],"extends":[119],"found":[121],"(limma":[125],"marray)":[127],"correct":[129],"dye":[131],"biases":[132],"spatial":[134],"artifacts.":[135],"wide":[139],"range":[140],"optional":[142],"customizable":[144],"filters":[145],"excluding":[147],"incorrect":[148],"signals":[149],"during":[150],"pre-processing":[152],"step.":[153],"displays":[155],"informative":[156],"output":[157],"plots,":[158],"enabling":[159],"user":[161],"monitor":[163],"process,":[166],"helps":[168],"adapt":[169],"method":[172],"appropriately":[173],"data.":[176],"All":[177],"these":[178],"analyses":[179],"graphical":[181],"outputs":[182],"presented":[184],"single":[187],"PDF":[188],"report.":[189],"CONCLUSION:":[190],"simple,":[193],"rapid":[194],"statistical":[202],"packages,":[204],"with":[205],"precise":[206],"control":[207],"visualization":[209],"results":[212],"obtained.":[213],"Complete":[214],"documentation,":[215],"examples":[216],"online":[218],"forms":[219],"setting":[221],"parameters":[223],"available":[225],"from":[226],"http://transcriptome.ens.fr/goulphar/.":[227]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-08-10T07:06:39.071514","created_date":"2025-10-10T00:00:00"}