{"id":"https://openalex.org/W1535247475","doi":"https://doi.org/10.1186/1471-2105-7-449","title":"Integrative missing value estimation for microarray data","display_name":"Integrative missing value estimation for microarray data","publication_year":2006,"publication_date":"2006-10-12","ids":{"openalex":"https://openalex.org/W1535247475","doi":"https://doi.org/10.1186/1471-2105-7-449","mag":"1535247475","pmid":"https://pubmed.ncbi.nlm.nih.gov/17038176"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-7-449","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-449","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-449","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-449","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080081719","display_name":"Jianjun Hu","orcid":"https://orcid.org/0000-0002-5177-399X"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianjun Hu","raw_affiliation_strings":["Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA 900089, USA. jianjunh@usc.edu","Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA 900089, USA. jianjunh@usc.edu","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100398345","display_name":"Haifeng Li","orcid":"https://orcid.org/0000-0002-3972-5573"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haifeng Li","raw_affiliation_strings":["Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105360062","display_name":"Michael S. Waterman","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S Waterman","raw_affiliation_strings":["Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050577808","display_name":"Xianghong Jasmine Zhou","orcid":"https://orcid.org/0000-0002-4522-7490"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xianghong Jasmine Zhou","raw_affiliation_strings":["Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 900089, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.2273,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.76176686,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"7","issue":"1","first_page":"449","last_page":"449"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.5440999865531921,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.5440999865531921,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.03590000048279762,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12303","display_name":"Tensor decomposition and applications","score":0.03500000014901161,"subfield":{"id":"https://openalex.org/subfields/2605","display_name":"Computational Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.8889994025230408},{"id":"https://openalex.org/keywords/imputation","display_name":"Imputation (statistics)","score":0.8279278874397278},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.7205324769020081},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6936883926391602},{"id":"https://openalex.org/keywords/preprocessor","display_name":"Preprocessor","score":0.5991470813751221},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.47745922207832336},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.45667171478271484},{"id":"https://openalex.org/keywords/data-pre-processing","display_name":"Data pre-processing","score":0.4313184320926666},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.32323241233825684},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2522590160369873},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.1845676600933075},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.17614218592643738}],"concepts":[{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.8889994025230408},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.8279278874397278},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.7205324769020081},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6936883926391602},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.5991470813751221},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.47745922207832336},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.45667171478271484},{"id":"https://openalex.org/C10551718","wikidata":"https://www.wikidata.org/wiki/Q5227332","display_name":"Data pre-processing","level":2,"score":0.4313184320926666},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.32323241233825684},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2522590160369873},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.1845676600933075},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17614218592643738},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-7-449","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-449","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-449","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17038176","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17038176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:scholarcommons.sc.edu:csce_facpub-1112","is_oa":true,"landing_page_url":"https://scholarcommons.sc.edu/csce_facpub/117","pdf_url":"https://scholarcommons.sc.edu/csce_facpub/117","source":{"id":"https://openalex.org/S4306401386","display_name":"Scholar Commons (University of South Carolina)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I155781252","host_organization_name":"University of South Carolina","host_organization_lineage":["https://openalex.org/I155781252"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:fea8c1962b344c0693740c3a028e44d7","is_oa":true,"landing_page_url":"https://doaj.org/article/fea8c1962b344c0693740c3a028e44d7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 7, Iss 1, p 449 (2006)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:1350595","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1622759","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1622759","is_oa":true,"landing_page_url":"http://doi.org/10.1186/1471-2105-7-449","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-7-449","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-449","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-449","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G866104454","display_name":"Collaborative Research: Endowing Biological Databases with Analytical Power: Indexing, Querying, and Mining of Complex Biological Structures","funder_award_id":"0515936","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1535247475.pdf","grobid_xml":"https://content.openalex.org/works/W1535247475.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1567694985","https://openalex.org/W1991537543","https://openalex.org/W2014620140","https://openalex.org/W2034162523","https://openalex.org/W2047446484","https://openalex.org/W2092265987","https://openalex.org/W2096863518","https://openalex.org/W2103453943","https://openalex.org/W2103835486","https://openalex.org/W2109204369","https://openalex.org/W2109205571","https://openalex.org/W2111104102","https://openalex.org/W2114933215","https://openalex.org/W2119253710","https://openalex.org/W2128330514","https://openalex.org/W2129815183","https://openalex.org/W2136714708","https://openalex.org/W2152155643","https://openalex.org/W2158940923","https://openalex.org/W2162142896","https://openalex.org/W2165011536","https://openalex.org/W2171118759","https://openalex.org/W2171802582"],"related_works":["https://openalex.org/W2181530120","https://openalex.org/W4211215373","https://openalex.org/W2024529227","https://openalex.org/W1574575415","https://openalex.org/W3144172081","https://openalex.org/W3179858851","https://openalex.org/W3028371478","https://openalex.org/W2081476516","https://openalex.org/W3149103228","https://openalex.org/W2379323287"],"abstract_inverted_index":{"BACKGROUND:":[0],"Missing":[1,65],"value":[2,81,168],"estimation":[3,169],"is":[4,24,175],"an":[5],"important":[6],"preprocessing":[7],"step":[8],"in":[9,51,147],"microarray":[10,76,180,202],"analysis.":[11],"Although":[12],"several":[13],"methods":[14],"have":[15],"been":[16],"developed":[17],"to":[18,78,144],"solve":[19],"this":[20],"problem,":[21],"their":[22],"performance":[23,205],"unsatisfactory":[25],"for":[26,113,178],"datasets":[27,50,77,181],"with":[28,86,182],"high":[29,34,188],"rates":[30,189],"of":[31,40,47,133,186,190,201,206],"missing":[32,80,87,167,191],"data,":[33,88,192],"measurement":[35],"noise,":[36],"or":[37,193],"limited":[38,184],"numbers":[39],"samples.":[41,59],"In":[42],"fact,":[43],"more":[44,217],"than":[45,57],"80%":[46],"the":[48,63,105,131,134,155,165,198,204],"time-series":[49],"Stanford":[52],"Microarray":[53],"Database":[54],"contain":[55],"less":[56],"eight":[58],"RESULTS:":[60],"We":[61,152],"present":[62],"integrative":[64,157],"Value":[66],"Estimation":[67],"method":[68],"(iMISS)":[69],"by":[70,95,142,213],"incorporating":[71,214],"information":[72],"from":[73],"multiple":[74],"reference":[75,97,107,219],"improve":[79,130],"estimation.":[82],"For":[83],"each":[84],"gene":[85],"we":[89,115],"derive":[90],"a":[91,117,183],"consistent":[92],"neighbor-gene":[93],"list":[94],"taking":[96],"data":[98,108],"sets":[99,109],"into":[100],"consideration.":[101],"To":[102],"determine":[103],"whether":[104],"given":[106],"are":[110],"sufficiently":[111],"informative":[112],"integration,":[114],"use":[116],"submatrix":[118],"imputation":[119,140,158],"approach.":[120],"Our":[121],"experiments":[122],"showed":[123],"that":[124,154],"iMISS":[125],"can":[126,160,209],"significantly":[127],"and":[128,174,216],"consistently":[129],"accuracy":[132],"state-of-the-art":[135,166],"Local":[136],"Least":[137],"Square":[138],"(LLS)":[139],"algorithm":[141],"up":[143],"15%":[145],"improvement":[146],"our":[148,207],"benchmark":[149],"tests.":[150],"CONCLUSION:":[151],"demonstrated":[153],"order-statistics-based":[156],"algorithms":[159],"achieve":[161],"significant":[162],"improvements":[163],"over":[164],"approaches":[170],"such":[171],"as":[172],"LLS":[173],"especially":[176],"good":[177],"imputing":[179],"number":[185],"samples,":[187],"very":[194],"noisy":[195],"measurements.":[196],"With":[197],"rapid":[199],"accumulation":[200],"datasets,":[203],"approach":[208],"be":[210],"further":[211],"improved":[212],"larger":[215],"appropriate":[218],"datasets.":[220]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}