{"id":"https://openalex.org/W1568976375","doi":"https://doi.org/10.1186/1471-2105-7-222","title":"A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data","display_name":"A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data","publication_year":2006,"publication_date":"2006-04-26","ids":{"openalex":"https://openalex.org/W1568976375","doi":"https://doi.org/10.1186/1471-2105-7-222","mag":"1568976375","pmid":"https://pubmed.ncbi.nlm.nih.gov/16638152"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-7-222","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-222","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-222","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-222","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100429700","display_name":"Zhuo Zhang","orcid":"https://orcid.org/0000-0002-0515-6288"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuo Zhang","raw_affiliation_strings":["Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China. zhangzhuo77@moon.ibp.ac.cn","Institute of Biophysics, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China. zhangzhuo77@moon.ibp.ac.cn","institution_ids":["https://openalex.org/I4210112540","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210112540","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108903761","display_name":"Shiwei Sun","orcid":"https://orcid.org/0000-0002-0351-3720"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiwei Sun","raw_affiliation_strings":["Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038128649","display_name":"Xiaopeng Zhu","orcid":"https://orcid.org/0000-0003-2007-9820"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaopeng Zhu","raw_affiliation_strings":["Institute of Biophysics, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Biophysics, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210112540"]},{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210112540","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019840354","display_name":"Suhua Chang","orcid":"https://orcid.org/0000-0001-7465-3985"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Suhua Chang","raw_affiliation_strings":["Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114406804","display_name":"Xiaofei Liu","orcid":"https://orcid.org/0000-0003-0922-3895"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofei Liu","raw_affiliation_strings":["Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083737928","display_name":"Chungong Yu","orcid":"https://orcid.org/0000-0003-3025-3415"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chungong Yu","raw_affiliation_strings":["Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076729236","display_name":"Dongbo Bu","orcid":"https://orcid.org/0000-0003-4119-4238"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dongbo Bu","raw_affiliation_strings":["Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029900952","display_name":"Runsheng Chen","orcid":"https://orcid.org/0000-0001-6049-8347"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Runsheng Chen","raw_affiliation_strings":["Institute of Biophysics, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","Institute of Biophysics, Chinese Academy of Sciences, Beijing, China","Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210112540"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, P. R, China","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"Institute of Biophysics, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210112540","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5029900952","https://openalex.org/A5076729236"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176","https://openalex.org/I4210112540"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.4183,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.7799318,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"7","issue":"1","first_page":"222","last_page":"222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9739999771118164,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9739999771118164,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.013899999670684338,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tandem-mass-spectrometry","display_name":"Tandem mass spectrometry","score":0.6643872261047363},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5498207211494446},{"id":"https://openalex.org/keywords/proteome","display_name":"Proteome","score":0.4715205430984497},{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"Mass spectrometry","score":0.47029897570610046},{"id":"https://openalex.org/keywords/sequence-database","display_name":"Sequence database","score":0.47012150287628174},{"id":"https://openalex.org/keywords/database-search-engine","display_name":"Database search engine","score":0.45956164598464966},{"id":"https://openalex.org/keywords/mascot","display_name":"Mascot","score":0.41844531893730164},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3622938394546509},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.34450268745422363},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.32354748249053955},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.29220128059387207},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.27261948585510254},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2716866135597229},{"id":"https://openalex.org/keywords/search-engine","display_name":"Search engine","score":0.1626911759376526},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.13979116082191467},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13085195422172546},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.12869220972061157}],"concepts":[{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.6643872261047363},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5498207211494446},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.4715205430984497},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.47029897570610046},{"id":"https://openalex.org/C41584329","wikidata":"https://www.wikidata.org/wiki/Q175902","display_name":"Sequence database","level":3,"score":0.47012150287628174},{"id":"https://openalex.org/C48000682","wikidata":"https://www.wikidata.org/wiki/Q5227411","display_name":"Database search engine","level":3,"score":0.45956164598464966},{"id":"https://openalex.org/C2778160393","wikidata":"https://www.wikidata.org/wiki/Q18670161","display_name":"Mascot","level":2,"score":0.41844531893730164},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3622938394546509},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34450268745422363},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.32354748249053955},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.29220128059387207},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27261948585510254},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2716866135597229},{"id":"https://openalex.org/C97854310","wikidata":"https://www.wikidata.org/wiki/Q19541","display_name":"Search engine","level":2,"score":0.1626911759376526},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.13979116082191467},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13085195422172546},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.12869220972061157},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-7-222","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-222","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-222","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16638152","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16638152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:6758bc738b414caea1e0a0546da7adc0","is_oa":false,"landing_page_url":"https://doaj.org/article/6758bc738b414caea1e0a0546da7adc0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 7, Iss 1, p 222 (2006)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:262504","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1463009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1463009","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1463009","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-7-222","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-222","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-222","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"},{"id":"https://openalex.org/F4320332588","display_name":"Shanghai Key Laboratory of Intelligent Information Processing","ror":"https://ror.org/013q1eq08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1568976375.pdf","grobid_xml":"https://content.openalex.org/works/W1568976375.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1543113652","https://openalex.org/W1979853788","https://openalex.org/W1981593008","https://openalex.org/W1986640734","https://openalex.org/W1995693931","https://openalex.org/W2000798961","https://openalex.org/W2005716310","https://openalex.org/W2016701426","https://openalex.org/W2026465178","https://openalex.org/W2028931227","https://openalex.org/W2035700643","https://openalex.org/W2058590378","https://openalex.org/W2059572899","https://openalex.org/W2062752098","https://openalex.org/W2073401456","https://openalex.org/W2078910808","https://openalex.org/W2085393537","https://openalex.org/W2086501380","https://openalex.org/W2093620473","https://openalex.org/W2107161977","https://openalex.org/W2109455023","https://openalex.org/W2112078820","https://openalex.org/W2150746288","https://openalex.org/W2157961977","https://openalex.org/W2335117233","https://openalex.org/W3136323740","https://openalex.org/W4247666721"],"related_works":["https://openalex.org/W2079578946","https://openalex.org/W2051515248","https://openalex.org/W2116007721","https://openalex.org/W1027044215","https://openalex.org/W2004515150","https://openalex.org/W116966121","https://openalex.org/W141129507","https://openalex.org/W2045985536","https://openalex.org/W1987445292","https://openalex.org/W2913733222"],"abstract_inverted_index":{"BACKGROUND:":[0],"Tandem":[1],"mass":[2,24,168],"spectrometry":[3,169],"(MS/MS)":[4],"is":[5,64],"a":[6,89,122,128,133,138,162],"powerful":[7],"tool":[8],"for":[9,94],"protein":[10],"identification.":[11],"Although":[12],"great":[13],"efforts":[14],"have":[15],"been":[16],"made":[17,35],"in":[18,36,42],"scoring":[19,47,62],"the":[20,71,75,79,84,105,108,111,116,149,159],"correlation":[21],"between":[22,55,107],"tandem":[23,167],"spectra":[25,160],"and":[26,49,57,83,110],"an":[27],"amino":[28],"acid":[29],"sequence":[30],"database,":[31],"improvements":[32],"could":[33],"be":[34],"three":[37],"aspects,":[38],"including":[39],"characterization":[40],"ofpeaks":[41],"spectra,":[43],"adoption":[44],"of":[45,53,74,86,156,166],"effective":[46],"functions":[48],"access":[50],"to":[51,69,103,126,170],"thereliability":[52],"matching":[54],"peptides":[56],"spectra.":[58,113],"RESULTS:":[59],"A":[60,153],"novel":[61],"function":[63],"presented,":[65],"along":[66],"with":[67,172],"criteria":[68],"estimate":[70],"performance":[72],"confidence":[73],"function.":[76],"Through":[77],"learning":[78],"typesof":[80],"product":[81],"ions":[82],"probability":[85],"generating":[87],"them,":[88],"hypothetic":[90,109],"spectrum":[91],"was":[92,101,124],"generated":[93],"each":[95],"candidate":[96],"peptide.":[97],"Then":[98],"relative":[99],"entropy":[100],"introduced":[102],"measure":[104],"similarity":[106],"observed":[112],"Based":[114],"on":[115,137],"extreme":[117],"value":[118],"distribution":[119],"(EVD)":[120],"theory,":[121],"threshold":[123],"chosen":[125],"distinguish":[127],"true":[129],"peptide":[130],"assignment":[131],"from":[132,158],"random":[134],"one.":[135],"Tests":[136],"public":[139],"MS/MS":[140],"dataset":[141],"demonstrated":[142],"that":[143],"this":[144],"method":[145],"performs":[146],"better":[147],"than":[148],"well-known":[150],"SEQUEST.":[151],"CONCLUSION:":[152],"reliable":[154],"identification":[155],"proteins":[157],"promises":[161],"more":[163],"efficient":[164],"application":[165],"proteomes":[171],"high":[173],"complexity.":[174]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}