{"id":"https://openalex.org/W1543018888","doi":"https://doi.org/10.1186/1471-2105-7-18","title":"In silico discovery of human natural antisense transcripts","display_name":"In silico discovery of human natural antisense transcripts","publication_year":2006,"publication_date":"2006-01-13","ids":{"openalex":"https://openalex.org/W1543018888","doi":"https://doi.org/10.1186/1471-2105-7-18","mag":"1543018888","pmid":"https://pubmed.ncbi.nlm.nih.gov/16409644"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-7-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-18","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-18","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-18","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082044814","display_name":"Yuanyuan Li","orcid":"https://orcid.org/0000-0003-3332-8128"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yuan-Yuan Li","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103137759","display_name":"Lei Qin","orcid":"https://orcid.org/0000-0001-5679-1591"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan-Yuan Li","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103137759","display_name":"Lei Qin","orcid":"https://orcid.org/0000-0001-5679-1591"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Qin","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103249197","display_name":"Zong-Ming Guo","orcid":null},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Zong-Ming Guo","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","The W. M. Keck Center for Comparative and Functional Genomics, University of Illinois at Urbana-Champaign, Urbana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"The W. M. Keck Center for Comparative and Functional Genomics, University of Illinois at Urbana-Champaign, Urbana, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110229329","display_name":"Lei Liu","orcid":"https://orcid.org/0000-0002-7053-6869"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Lei Liu","raw_affiliation_strings":["The W. M. Keck Center for Comparative and Functional Genomics, University of Illinois at Urbana-Champaign, 1201 W. Gregory Dr., Urbana, Illinois, 61801, USA","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The W. M. Keck Center for Comparative and Functional Genomics, University of Illinois at Urbana-Champaign, 1201 W. Gregory Dr., Urbana, Illinois, 61801, USA","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084581495","display_name":"Pei Hao","orcid":"https://orcid.org/0000-0002-1498-7059"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Xu","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084581495","display_name":"Pei Hao","orcid":"https://orcid.org/0000-0002-1498-7059"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pei Hao","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066390529","display_name":"Jiong Su","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiong Su","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113757175","display_name":"Yi\u2010Xiang Shi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yixiang Shi","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102482201","display_name":"Weizhong He","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei-Zhong He","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","Shanghai Center for Bioinformation Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, 200235, China","institution_ids":["https://openalex.org/I4210162648"]},{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008280608","display_name":"Yixue Li","orcid":"https://orcid.org/0000-0002-1198-7176"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yi-Xue Li","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","institution_ids":["https://openalex.org/I4210162648"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008280608","display_name":"Yixue Li","orcid":"https://orcid.org/0000-0002-1198-7176"},"institutions":[{"id":"https://openalex.org/I4210162648","display_name":"Shanghai Center For Bioinformation Technology","ror":"https://ror.org/04nyf1f54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210162648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi-Xue Li","raw_affiliation_strings":["Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Center for Bioinformation Technology, Shanghai 200235, China. yyli@scbit.org","institution_ids":["https://openalex.org/I4210162648"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008280608","https://openalex.org/A5082044814","https://openalex.org/A5102482201"],"corresponding_institution_ids":["https://openalex.org/I4210162648"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2790},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2790},"fwci":2.7955,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.90057951,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"7","issue":"1","first_page":"18","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.6043000221252441,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.6043000221252441,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.20160000026226044,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.07440000027418137,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.7339258790016174},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7137194871902466},{"id":"https://openalex.org/keywords/refseq","display_name":"RefSeq","score":0.6497641801834106},{"id":"https://openalex.org/keywords/nat","display_name":"Nat","score":0.6106693148612976},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5966431498527527},{"id":"https://openalex.org/keywords/splice","display_name":"splice","score":0.5910155177116394},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.5756928324699402},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5506017208099365},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5004897117614746},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.4396756887435913},{"id":"https://openalex.org/keywords/antisense-rna","display_name":"Antisense RNA","score":0.4386010766029358},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"Alternative splicing","score":0.42464566230773926},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.29489666223526},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.23167026042938232},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.23146405816078186},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.21347886323928833},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.12206968665122986}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.7339258790016174},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7137194871902466},{"id":"https://openalex.org/C151810110","wikidata":"https://www.wikidata.org/wiki/Q7307074","display_name":"RefSeq","level":4,"score":0.6497641801834106},{"id":"https://openalex.org/C182516595","wikidata":"https://www.wikidata.org/wiki/Q376660","display_name":"Nat","level":2,"score":0.6106693148612976},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5966431498527527},{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.5910155177116394},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.5756928324699402},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5506017208099365},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5004897117614746},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4396756887435913},{"id":"https://openalex.org/C202416437","wikidata":"https://www.wikidata.org/wiki/Q423832","display_name":"Antisense RNA","level":4,"score":0.4386010766029358},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.42464566230773926},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29489666223526},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.23167026042938232},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.23146405816078186},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.21347886323928833},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.12206968665122986},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-7-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-18","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-18","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16409644","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16409644","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:c8db7bf840da419789db9b4f4abb5ef6","is_oa":false,"landing_page_url":"https://doaj.org/article/c8db7bf840da419789db9b4f4abb5ef6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 7, Iss 1, p 18 (2006)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:112039","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1369008","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1369008","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1369008","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-7-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-7-18","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-18","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1543018888.pdf","grobid_xml":"https://content.openalex.org/works/W1543018888.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1532161523","https://openalex.org/W1535914077","https://openalex.org/W1966585515","https://openalex.org/W1968985953","https://openalex.org/W1971298388","https://openalex.org/W1982828716","https://openalex.org/W1989841259","https://openalex.org/W1991426319","https://openalex.org/W1993991759","https://openalex.org/W1996164869","https://openalex.org/W2009396375","https://openalex.org/W2010717835","https://openalex.org/W2019377841","https://openalex.org/W2020482800","https://openalex.org/W2022523272","https://openalex.org/W2032057086","https://openalex.org/W2033713596","https://openalex.org/W2045925077","https://openalex.org/W2053677420","https://openalex.org/W2056385746","https://openalex.org/W2078534230","https://openalex.org/W2081979449","https://openalex.org/W2085385454","https://openalex.org/W2100204438","https://openalex.org/W2105912300","https://openalex.org/W2107474451","https://openalex.org/W2108222684","https://openalex.org/W2109291482","https://openalex.org/W2109905272","https://openalex.org/W2111548417","https://openalex.org/W2119736484","https://openalex.org/W2131470746","https://openalex.org/W2138664009","https://openalex.org/W2142088985","https://openalex.org/W2142445831","https://openalex.org/W2144253115","https://openalex.org/W2158156090","https://openalex.org/W2162825358","https://openalex.org/W2166593443","https://openalex.org/W2170119276","https://openalex.org/W4243726969","https://openalex.org/W4296874249"],"related_works":["https://openalex.org/W2173732482","https://openalex.org/W2167922509","https://openalex.org/W2383430300","https://openalex.org/W4388652965","https://openalex.org/W2355747264","https://openalex.org/W2107903949","https://openalex.org/W12006945","https://openalex.org/W4386739095","https://openalex.org/W2052297191","https://openalex.org/W2136075631"],"abstract_inverted_index":{"BACKGROUND:":[0],"Several":[1],"high-throughput":[2],"searches":[3],"for":[4,56],"potential":[5],"natural":[6],"antisense":[7,78],"transcripts":[8,31,212],"(NATs)":[9],"have":[10,41,116],"been":[11],"performed":[12],"recently,":[13],"but":[14],"most":[15],"of":[16,29,37,74,87,101,106,130,139,157,211],"the":[17,57,71,98,155,215],"reports":[18],"were":[19,172],"focused":[20],"on":[21,162],"cis":[22],"type.":[23,68],"A":[24],"thorough":[25],"in":[26,142,150],"silico":[27],"analysis":[28],"human":[30,46],"will":[32],"help":[33],"expand":[34],"our":[35],"knowledge":[36],"NATs.":[38],"RESULTS:":[39],"We":[40],"identified":[42],"568":[43],"NATs":[44,53,65,186],"from":[45,165],"RefSeq":[47],"RNA":[48,79],"sequences.":[49],"Among":[50,103],"them,":[51],"403":[52],"are":[54,66,82],"reported":[55],"first":[58],"time,":[59],"and":[60,77,133,144,181,192],"at":[61],"least":[62],"157":[63],"novel":[64],"trans":[67],"According":[69],"to":[70,174,214],"pairing":[72,118,147],"region":[73],"a":[75,104,151,208],"sense":[76],"pair,":[80],"hNATs":[81,143,203],"divided":[83],"into":[84],"6":[85],"classes,":[86],"which":[88],"about":[89],"87%":[90],"involve":[91],"5'":[92],"or":[93,121],"3'":[94],"UTR":[95],"sequences,":[96],"supporting":[97],"regulatory":[99],"role":[100],"UTRs.":[102],"total":[105],"535":[107],"NAT":[108],"pairs":[109,171],"related":[110],"with":[111,199],"splice":[112,140],"variants,":[113],"77.4%":[114],"(414/535)":[115],"their":[117],"regions":[119],"affected":[120],"completely":[122],"eliminated":[123],"by":[124],"alternative":[125,131],"splicing,":[126],"suggesting":[127],"significant":[128,176],"relationship":[129],"splicing":[132],"antisense-directed":[134],"regulation.":[135],"The":[136],"extensive":[137,191],"occurrence":[138],"variants":[141],"other":[145],"multiple":[146],"patterns":[148,179],"results":[149],"one-to-many":[152],"relationship,":[153],"allowing":[154],"formation":[156],"complex":[158,193,216],"regulation":[159,217],"networks.":[160,218],"Based":[161],"microarray":[163],"data":[164],"Stanford":[166],"Microarray":[167],"Database,":[168],"two":[169],"hNAT":[170],"found":[173],"display":[175],"inverse":[177],"expression":[178],"before":[180],"after":[182],"insulin":[183],"injection.":[184],"CONCLUSION:":[185],"might":[187],"carry":[188],"out":[189],"more":[190],"functions":[194],"than":[195],"previously":[196],"thought.":[197],"Combined":[198],"endogenous":[200],"micro":[201],"RNAs,":[202],"could":[204],"be":[205],"regarded":[206],"as":[207],"special":[209],"group":[210],"contributing":[213]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}