{"id":"https://openalex.org/W1882274632","doi":"https://doi.org/10.1186/1471-2105-6-297","title":"InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data","display_name":"InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data","publication_year":2005,"publication_date":"2005-12-12","ids":{"openalex":"https://openalex.org/W1882274632","doi":"https://doi.org/10.1186/1471-2105-6-297","mag":"1882274632","pmid":"https://pubmed.ncbi.nlm.nih.gov/16343334"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-6-297","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-6-297","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-6-297","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-6-297","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Lalitha Viswanath","orcid":null},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lalitha Viswanath","raw_affiliation_strings":["School of Informatics, Indiana University, Bloomington, Indiana, 47405, USA. lviswana@indiana.edu","School of Informatics, Indiana University, Bloomington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Informatics, Indiana University, Bloomington, Indiana, 47405, USA. lviswana@indiana.edu","institution_ids":["https://openalex.org/I4210119109"]},{"raw_affiliation_string":"School of Informatics, Indiana University, Bloomington, USA","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002349936","display_name":"Elizabeth A. Housworth","orcid":null},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth A Housworth","raw_affiliation_strings":["Departments of Mathematics and Biology, Indiana University, Bloomington, Indiana, 47405, USA","Departments of Mathematics and Biology, Indiana University, Bloomington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Mathematics and Biology, Indiana University, Bloomington, Indiana, 47405, USA","institution_ids":["https://openalex.org/I4210119109"]},{"raw_affiliation_string":"Departments of Mathematics and Biology, Indiana University, Bloomington, USA","institution_ids":["https://openalex.org/I4210119109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210119109"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.06295128,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"6","issue":"1","first_page":"297","last_page":"297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.4530999958515167,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.4530999958515167,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.14550000429153442,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10733","display_name":"Wheat and Barley Genetics and Pathology","score":0.056699998676776886,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5546174645423889},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.512428343296051},{"id":"https://openalex.org/keywords/locus","display_name":"Locus (genetics)","score":0.4934741258621216},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4744062125682831},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.430152028799057},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3476024270057678},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3459232747554779},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1290663480758667}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5546174645423889},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.512428343296051},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.4934741258621216},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4744062125682831},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.430152028799057},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3476024270057678},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3459232747554779},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1290663480758667},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-6-297","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-6-297","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-6-297","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16343334","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16343334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:c65a70b01b85400a96bf022c87e01ec5","is_oa":false,"landing_page_url":"https://doaj.org/article/c65a70b01b85400a96bf022c87e01ec5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 6, Iss 1, p 297 (2005)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1327689","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1327689","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-6-297","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-6-297","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-6-297","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4022644576","display_name":"Modeling Recombination","funder_award_id":"0306243","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1882274632.pdf","grobid_xml":"https://content.openalex.org/works/W1882274632.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W291545442","https://openalex.org/W598322998","https://openalex.org/W1751477646","https://openalex.org/W1760690168","https://openalex.org/W1839107686","https://openalex.org/W1933946532","https://openalex.org/W1963809100","https://openalex.org/W2001395487","https://openalex.org/W2045312727","https://openalex.org/W2073085152","https://openalex.org/W2101780276","https://openalex.org/W2101884817","https://openalex.org/W2104862908","https://openalex.org/W2120064905","https://openalex.org/W2140169741","https://openalex.org/W2142860698","https://openalex.org/W2144086013","https://openalex.org/W2148296422","https://openalex.org/W2342117587","https://openalex.org/W2554183340","https://openalex.org/W3149753677"],"related_works":["https://openalex.org/W2056064843","https://openalex.org/W2133790197","https://openalex.org/W2124724808","https://openalex.org/W2589149327","https://openalex.org/W2147212144","https://openalex.org/W2182810250","https://openalex.org/W2115675860","https://openalex.org/W2052173596","https://openalex.org/W1886625688","https://openalex.org/W2028554823"],"abstract_inverted_index":{"BACKGROUND:":[0],"Good":[1],"statistical":[2,167],"models":[3],"for":[4,76,121,169],"analyzing":[5],"and":[6,26,96,124,134,152,165],"simulating":[7],"multilocus":[8,127,143],"recombination":[9,128],"data":[10,145],"exist":[11],"but":[12],"are":[13],"not":[14],"accessible":[15,87],"to":[16,35,40,72,88,162],"many":[17,45],"biologists":[18],"because":[19],"their":[20],"use":[21,133],"requires":[22],"reasonably":[23],"sophisticated":[24],"mathematical":[25],"computational":[27],"implementation.":[28],"While":[29],"some":[30],"labs":[31,46,89],"have":[32,50],"direct":[33],"access":[34,161],"statisticians":[36],"or":[37,102],"programmers":[38],"competent":[39],"carry":[41,64],"out":[42,65],"such":[43,66],"analyses,":[44],"do":[47],"not.":[48],"We":[49,107,130],"created":[51],"a":[52,113],"platform":[53],"independent":[54],"application":[55],"with":[56,112,139],"an":[57,110,140],"easy-to-use":[58],"graphical":[59,115],"user":[60],"interface":[61,116],"that":[62,90],"will":[63],"analyses":[67],"including":[68],"the":[69,77,122,132,137,147,153,163,170],"simulations":[70],"needed":[71],"bootstrap":[73],"confidence":[74],"intervals":[75],"parameters":[78],"of":[79,126,136,142,173],"interest.":[80],"This":[81],"software":[82],"should":[83],"make":[84],"multi-locus":[85,171],"techniques":[86],"previously":[91,118],"relied":[92],"on":[93],"less":[94],"powerful":[95,164],"potentially":[97],"statistically":[98],"confounded":[99],"single":[100],"interval":[101,104],"double":[103],"techniques.":[105],"RESULTS:":[106],"introduce":[108],"InterferenceAnalyzer,":[109],"implementation":[111],"user-friendly":[114],"incorporating":[117],"developed":[119],"algorithms":[120],"analysis":[123,172],"simulation":[125],"data.":[129,175],"demonstrate":[131],"features":[135],"program":[138],"example":[141],"tetrad":[144],"from":[146],"mustard":[148],"plant,":[149],"Arabidopsis":[150],"thaliana,":[151],"yeast,":[154],"Saccharomyces":[155],"cerevisiae.":[156],"CONCLUSION:":[157],"InterferenceAnalyzer":[158],"provides":[159],"easy":[160],"appropriate":[166],"tools":[168],"genetic":[174]},"counts_by_year":[{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}