{"id":"https://openalex.org/W2131712883","doi":"https://doi.org/10.1186/1471-2105-5-68","title":"Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma","display_name":"Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma","publication_year":2004,"publication_date":"2004-06-03","ids":{"openalex":"https://openalex.org/W2131712883","doi":"https://doi.org/10.1186/1471-2105-5-68","mag":"2131712883","pmid":"https://pubmed.ncbi.nlm.nih.gov/15176974"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-5-68","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-5-68","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-5-68","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-5-68","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047397152","display_name":"Andrea Bisognin","orcid":"https://orcid.org/0000-0002-9114-1508"},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Bisognin","raw_affiliation_strings":["Department of Biology, University of Padua, 35131, Padova, Italy. bisio@medgen.univr.it","Dept. of Biology, University of Padua - Italy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Padua, 35131, Padova, Italy. bisio@medgen.univr.it","institution_ids":["https://openalex.org/I138689650"]},{"raw_affiliation_string":"Dept. of Biology, University of Padua - Italy;","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054227897","display_name":"Stefania Bortoluzzi","orcid":"https://orcid.org/0000-0001-8240-3070"},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefania Bortoluzzi","raw_affiliation_strings":["Department of Biology, University of Padua, via Ugo Bassi 58B, 35131, Padova, Italy","Dept. of Biology, University of Padua - Italy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Padua, via Ugo Bassi 58B, 35131, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]},{"raw_affiliation_string":"Dept. of Biology, University of Padua - Italy;","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113594355","display_name":"Gian Antonio Danieli","orcid":null},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Gian Antonio Danieli","raw_affiliation_strings":["Department of Biology, University of Padua, via Ugo Bassi 58B, 35131, Padova, Italy","Dept. of Biology, University of Padua - Italy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Padua, via Ugo Bassi 58B, 35131, Padova, Italy","institution_ids":["https://openalex.org/I138689650"]},{"raw_affiliation_string":"Dept. of Biology, University of Padua - Italy;","institution_ids":["https://openalex.org/I138689650"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5113594355"],"corresponding_institution_ids":["https://openalex.org/I138689650"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.7799,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.77596054,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"5","issue":"1","first_page":"68","last_page":"68"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.8391000032424927,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.8391000032424927,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.03590000048279762,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhabdomyosarcoma","display_name":"Rhabdomyosarcoma","score":0.8419759273529053},{"id":"https://openalex.org/keywords/alveolar-rhabdomyosarcoma","display_name":"Alveolar rhabdomyosarcoma","score":0.8160831928253174},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6930428147315979},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5966222882270813},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"Skeletal muscle","score":0.5535889267921448},{"id":"https://openalex.org/keywords/perl","display_name":"Perl","score":0.5004613399505615},{"id":"https://openalex.org/keywords/comparative-genomic-hybridization","display_name":"Comparative genomic hybridization","score":0.4516793489456177},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4440966844558716},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.42847955226898193},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.3505312502384186},{"id":"https://openalex.org/keywords/sarcoma","display_name":"Sarcoma","score":0.21116715669631958},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.20072636008262634},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.09958088397979736},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.08825954794883728},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.08251592516899109}],"concepts":[{"id":"https://openalex.org/C2780844630","wikidata":"https://www.wikidata.org/wiki/Q1898141","display_name":"Rhabdomyosarcoma","level":3,"score":0.8419759273529053},{"id":"https://openalex.org/C2776522094","wikidata":"https://www.wikidata.org/wiki/Q4737958","display_name":"Alveolar rhabdomyosarcoma","level":4,"score":0.8160831928253174},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6930428147315979},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5966222882270813},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.5535889267921448},{"id":"https://openalex.org/C2777002779","wikidata":"https://www.wikidata.org/wiki/Q42478","display_name":"Perl","level":2,"score":0.5004613399505615},{"id":"https://openalex.org/C124942203","wikidata":"https://www.wikidata.org/wiki/Q656638","display_name":"Comparative genomic hybridization","level":4,"score":0.4516793489456177},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4440966844558716},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.42847955226898193},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.3505312502384186},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.21116715669631958},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20072636008262634},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.09958088397979736},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08825954794883728},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08251592516899109},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018232","descriptor_name":"Rhabdomyosarcoma, Alveolar","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018232","descriptor_name":"Rhabdomyosarcoma, Alveolar","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018232","descriptor_name":"Rhabdomyosarcoma, Alveolar","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041321","descriptor_name":"Chromosomes, Human, X","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D041321","descriptor_name":"Chromosomes, Human, X","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D041321","descriptor_name":"Chromosomes, Human, X","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052138","descriptor_name":"Genes, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052138","descriptor_name":"Genes, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052138","descriptor_name":"Genes, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-5-68","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-5-68","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-5-68","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:15176974","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15176974","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:aef42efd4a4e43659ba16ecde287c983","is_oa":false,"landing_page_url":"https://doaj.org/article/aef42efd4a4e43659ba16ecde287c983","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 5, Iss 1, p 68 (2004)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:102851","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC446182","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:446182","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/446182","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:www.research.unipd.it:11577/2439758","is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/2439758","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-5-68","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-5-68","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-5-68","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2131712883.pdf","grobid_xml":"https://content.openalex.org/works/W2131712883.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W79775631","https://openalex.org/W1484187172","https://openalex.org/W1727290854","https://openalex.org/W1968046362","https://openalex.org/W1978423911","https://openalex.org/W1979805366","https://openalex.org/W1992844463","https://openalex.org/W1997872562","https://openalex.org/W1999872588","https://openalex.org/W2012617920","https://openalex.org/W2043701239","https://openalex.org/W2069644796","https://openalex.org/W2100950671","https://openalex.org/W2102999073","https://openalex.org/W2117284234","https://openalex.org/W2130951034","https://openalex.org/W2134432289","https://openalex.org/W2141683819","https://openalex.org/W2151793483","https://openalex.org/W2161178884","https://openalex.org/W2162748174","https://openalex.org/W2165270659","https://openalex.org/W2168909179","https://openalex.org/W2297165308","https://openalex.org/W2596938854"],"related_works":["https://openalex.org/W3120772093","https://openalex.org/W2319335184","https://openalex.org/W2109773521","https://openalex.org/W2077360061","https://openalex.org/W2314634167","https://openalex.org/W4310578667","https://openalex.org/W2003632667","https://openalex.org/W920112307","https://openalex.org/W2588161250","https://openalex.org/W3001722625"],"abstract_inverted_index":{"BACKGROUND:":[0],"Rhabdomyosarcoma":[1],"is":[2],"a":[3,94,130,170],"relatively":[4],"common":[5],"tumour":[6,43],"of":[7,16,20,26,42,72,75,93,109,156,180,212,223],"the":[8,173,177],"soft":[9],"tissue,":[10],"probably":[11],"due":[12],"to":[13,66,122,154],"regulatory":[14],"disruption":[15],"growth":[17],"and":[18,34,48,51,172,185,198],"differentiation":[19],"skeletal":[21,32,115,158,196],"muscle":[22,33,197],"stem":[23],"cells.":[24],"Identification":[25],"genes":[27,110,137,151,208],"differentially":[28],"expressed":[29,111,139],"in":[30,35,39,45,52,112,140,162,183,194,199,210],"normal":[31],"rhabdomyosarcoma":[36,113,141,214],"may":[37],"help":[38],"understanding":[40],"mechanisms":[41],"development,":[44],"discovering":[46],"diagnostic":[47],"prognostic":[49],"markers":[50],"identifying":[53],"novel":[54],"targets":[55,217],"for":[56,98,176,206,218],"drug":[57,219],"therapy.":[58],"RESULTS:":[59],"A":[60],"Perl-code":[61],"web":[62],"client":[63],"was":[64,120],"developed":[65,121,169],"automatically":[67],"obtain":[68],"genome":[69],"map":[70],"positions":[71],"large":[73],"sets":[74],"genes.":[76],"The":[77],"software,":[78],"based":[79],"on":[80,83],"automatic":[81],"search":[82],"Human":[84],"Genome":[85],"Browser":[86],"by":[87,128],"sequence":[88,97],"alignment,":[89],"only":[90],"requires":[91],"availability":[92],"single":[95],"transcribed":[96],"each":[99],"gene.":[100],"In":[101,165],"this":[102,166],"way,":[103],"we":[104,168,186],"obtained":[105],"tissue-specific":[106],"chromosomal":[107,134,146,188],"maps":[108],"or":[114],"muscle.":[116],"Subsequently,":[117],"Perl":[118],"software":[119,175],"calculate":[123],"gene":[124,192],"density":[125],"along":[126],"chromosomes,":[127],"using":[129],"sliding":[131],"window.":[132],"Thirty-three":[133],"regions":[135,147,205],"harbouring":[136,207],"mostly":[138],"were":[142,148],"identified.":[143],"Similarly,":[144],"48":[145],"detected":[149],"including":[150],"possibly":[152],"related":[153],"function":[155],"differentiated":[157],"muscle,":[159],"but":[160],"silenced":[161],"rhabdomyosarcoma.":[163],"CONCLUSION:":[164],"study":[167],"method":[171],"associated":[174],"comparative":[178],"analysis":[179],"genomic":[181],"expression":[182,193],"tissues":[184],"identified":[187],"segments":[189],"showing":[190],"differential":[191],"human":[195],"alveolar":[200,213],"rhabdomyosarcoma,":[201],"appearing":[202],"as":[203],"candidate":[204],"involved":[209],"origin":[211],"representing":[215],"possible":[216],"treatment":[220],"and/or":[221],"development":[222],"tumor":[224],"markers.":[225]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-06-15T08:34:33.830935","created_date":"2025-10-10T00:00:00"}