{"id":"https://openalex.org/W2146983134","doi":"https://doi.org/10.1186/1471-2105-2-5","title":"A study of quality measures for protein threading models","display_name":"A study of quality measures for protein threading models","publication_year":2001,"publication_date":"2001-08-01","ids":{"openalex":"https://openalex.org/W2146983134","doi":"https://doi.org/10.1186/1471-2105-2-5","mag":"2146983134","pmid":"https://pubmed.ncbi.nlm.nih.gov/11545673"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-2-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-2-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-2-5.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-2-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064474850","display_name":"Susana Crist\u00f3bal","orcid":"https://orcid.org/0000-0002-3894-2218"},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Susana Cristobal","raw_affiliation_strings":["Cell and Molecular Biology Department, Box 596. BMC Uppsala University, SE-751 24 Uppsala, Sweden. susana.cristobal@icm.uu.se","Cell and Molecular Biology Department, BMC Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell and Molecular Biology Department, Box 596. BMC Uppsala University, SE-751 24 Uppsala, Sweden. susana.cristobal@icm.uu.se","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Cell and Molecular Biology Department, BMC Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083445132","display_name":"Adam Zem\u0142a","orcid":"https://orcid.org/0000-0003-0504-8647"},"institutions":[{"id":"https://openalex.org/I1282311441","display_name":"Lawrence Livermore National Laboratory","ror":"https://ror.org/041nk4h53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282311441","https://openalex.org/I1330989302","https://openalex.org/I198811213","https://openalex.org/I4210138311"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Zemla","raw_affiliation_strings":["Lawrence Livermore National Laboratory, 7000 East Ave., Livermore, CA, 94550-9234, USA","Lawrence Livermore National Laboratory Livermore USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawrence Livermore National Laboratory, 7000 East Ave., Livermore, CA, 94550-9234, USA","institution_ids":["https://openalex.org/I1282311441"]},{"raw_affiliation_string":"Lawrence Livermore National Laboratory Livermore USA","institution_ids":["https://openalex.org/I1282311441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048857636","display_name":"Daniel Fischer","orcid":"https://orcid.org/0000-0002-7513-683X"},"institutions":[{"id":"https://openalex.org/I124227911","display_name":"Ben-Gurion University of the Negev","ror":"https://ror.org/05tkyf982","country_code":"IL","type":"education","lineage":["https://openalex.org/I124227911"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Daniel Fischer","raw_affiliation_strings":["Department Bioinformatics/Computer Science, Ben Gurion University, Beer-Sheva, 84015, Israel","Department Bioinformatics/Computer Science, Ben Gurion University, Beer-Sheva, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Bioinformatics/Computer Science, Ben Gurion University, Beer-Sheva, 84015, Israel","institution_ids":["https://openalex.org/I124227911"]},{"raw_affiliation_string":"Department Bioinformatics/Computer Science, Ben Gurion University, Beer-Sheva, Israel","institution_ids":["https://openalex.org/I124227911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036708265","display_name":"Leszek Rychlewski","orcid":null},"institutions":[{"id":"https://openalex.org/I4210120699","display_name":"International Institute of Molecular and Cell Biology","ror":"https://ror.org/01y3dkx74","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210120699"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Leszek Rychlewski","raw_affiliation_strings":["International Institute of Molecular and Cell Biology, Ks. Trojdena 4, 02-109, Warsaw, Poland","International Institute of Molecular and Cell Biology\u2028Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Institute of Molecular and Cell Biology, Ks. Trojdena 4, 02-109, Warsaw, Poland","institution_ids":["https://openalex.org/I4210120699"]},{"raw_affiliation_string":"International Institute of Molecular and Cell Biology\u2028Warsaw, Poland","institution_ids":["https://openalex.org/I4210120699"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072903725","display_name":"Arne Elofsson","orcid":"https://orcid.org/0000-0002-7115-9751"},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Arne Elofsson","raw_affiliation_strings":["Stockholm Bioinformatics Center, Stockholm University, SE-106 91, Stockholm, Sweden","Stockholm Bioinformatics Center Stockholm University, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stockholm Bioinformatics Center, Stockholm University, SE-106 91, Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684"]},{"raw_affiliation_string":"Stockholm Bioinformatics Center Stockholm University, Stockholm, Sweden","institution_ids":["https://openalex.org/I161593684"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072903725"],"corresponding_institution_ids":["https://openalex.org/I161593684"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":2.574,"has_fulltext":true,"cited_by_count":220,"citation_normalized_percentile":{"value":0.90108064,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"2","issue":"1","first_page":"5","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.8305000066757202,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.8305000066757202,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.04280000180006027,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/casp","display_name":"CASP","score":0.9571805000305176},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.6826776266098022},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.6797674894332886},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6141201257705688},{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.574916422367096},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5524291396141052},{"id":"https://openalex.org/keywords/threading","display_name":"Threading (protein sequence)","score":0.5329747200012207},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.48936909437179565},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.45663172006607056},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.41975387930870056},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3917158544063568},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3787332773208618},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.22013115882873535},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17349392175674438},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15181586146354675}],"concepts":[{"id":"https://openalex.org/C66153294","wikidata":"https://www.wikidata.org/wiki/Q899291","display_name":"CASP","level":4,"score":0.9571805000305176},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.6826776266098022},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.6797674894332886},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6141201257705688},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.574916422367096},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5524291396141052},{"id":"https://openalex.org/C200307862","wikidata":"https://www.wikidata.org/wiki/Q7797175","display_name":"Threading (protein sequence)","level":3,"score":0.5329747200012207},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.48936909437179565},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.45663172006607056},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.41975387930870056},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3917158544063568},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3787332773208618},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.22013115882873535},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17349392175674438},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15181586146354675},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-2-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-2-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-2-5.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:11545673","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11545673","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:d1d3ac5582de42809175026655509779","is_oa":true,"landing_page_url":"https://doaj.org/article/d1d3ac5582de42809175026655509779","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 2, Iss 1, p 5 (2001)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:976478","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/55330","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-2-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-2-5","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-2-5.pdf","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320940","display_name":"Stiftelsen f\u00f6r\u00a0Strategisk Forskning","ror":"https://ror.org/044wr7g58"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2146983134.pdf","grobid_xml":"https://content.openalex.org/works/W2146983134.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1963726977","https://openalex.org/W1965910641","https://openalex.org/W1979938039","https://openalex.org/W1989777815","https://openalex.org/W1991538681","https://openalex.org/W1996357466","https://openalex.org/W2005049999","https://openalex.org/W2010461327","https://openalex.org/W2011769393","https://openalex.org/W2027289849","https://openalex.org/W2038714686","https://openalex.org/W2040644205","https://openalex.org/W2045103836","https://openalex.org/W2053857844","https://openalex.org/W2056807348","https://openalex.org/W2058336694","https://openalex.org/W2075756833","https://openalex.org/W2078138505","https://openalex.org/W2080336769","https://openalex.org/W2085277871","https://openalex.org/W2088083202","https://openalex.org/W2109001995","https://openalex.org/W2139279375","https://openalex.org/W2150926737","https://openalex.org/W2155479906","https://openalex.org/W2157938277","https://openalex.org/W2157975034","https://openalex.org/W2166133396","https://openalex.org/W2168937592","https://openalex.org/W2611400920","https://openalex.org/W4205995961","https://openalex.org/W4230638849","https://openalex.org/W4233785461","https://openalex.org/W4238388397","https://openalex.org/W4241935390","https://openalex.org/W4242046528","https://openalex.org/W4242592913","https://openalex.org/W4243775915","https://openalex.org/W4245041822","https://openalex.org/W4255401807","https://openalex.org/W4256395558"],"related_works":["https://openalex.org/W2411998238","https://openalex.org/W2462594639","https://openalex.org/W2117340986","https://openalex.org/W2136856901","https://openalex.org/W1888349473","https://openalex.org/W2335447195","https://openalex.org/W2159298533","https://openalex.org/W2098138211","https://openalex.org/W2005312858","https://openalex.org/W2160879227"],"abstract_inverted_index":{"BACKGROUND:":[0],"Prediction":[1],"of":[2,7,43,55,63,69,111,162,180,186,196,215,234,258,295,308,331,350],"protein":[3,44],"structures":[4],"is":[5,24,191,209,224,326],"one":[6],"the":[8,39,53,61,70,78,122,144,153,219,232,235,240,259,262,273,292,296,310,324,329,335,341],"fundamental":[9],"challenges":[10],"in":[11,37,88,103,108,125,338,339,359],"biology":[12],"today.":[13],"To":[14,65],"fully":[15,96],"understand":[16],"how":[17,210],"well":[18,106,130],"different":[19,56,67,167,216,222],"prediction":[20],"methods":[21,173],"perform,":[22],"it":[23],"necessary":[25],"to":[26,51,58,94,141,150,211,246,287,327,346],"use":[27,347],"measures":[28,73,83,98,120,123,133,181,195,208,223,228,268,285,314],"that":[29,99,171,201,239,282,303],"evaluate":[30,52],"their":[31,139],"performance.":[32],"Every":[33],"two":[34],"years,":[35],"starting":[36],"1994,":[38],"CASP":[40,79],"(Critical":[41],"Assessment":[42],"Structure":[45],"Prediction)":[46],"process":[47],"has":[48],"been":[49,75,86],"organized":[50],"ability":[54,140],"predictors":[57,297],"blindly":[59],"predict":[60],"structure":[62],"proteins.":[64],"capture":[66],"features":[68],"models,":[71],"several":[72,360],"have":[74,84,115,132,137,316],"developed":[76],"during":[77],"processes.":[80],"However,":[81],"these":[82],"not":[85],"examined":[87],"detail":[89],"before.":[90],"In":[91],"an":[92],"attempt":[93],"develop":[95],"automatic":[97,207,250,284,313],"can":[100,243],"be":[101,244,345],"used":[102,124,358],"CASP,":[104],"as":[105,107,129,131,226,357],"other":[109],"type":[110,330],"benchmarking":[112],"experiments,":[113],"we":[114,169,280],"compared":[116],"twenty-one":[117],"measures.":[118,251],"These":[119],"include":[121],"CASP3":[126,151],"and":[127,146,152,312,353],"CASP2":[128],"introduced":[134],"later.":[135],"We":[136,199,237,301],"studied":[138],"distinguish":[142],"between":[143,155,221],"better":[145,270],"worse":[147],"models":[148,164,260,275],"submitted":[149],"correlation":[154,184,190],"them.":[156],"RESULTS:":[157],"Using":[158],"a":[159,183,202,288,305,348],"small":[160],"set":[161],"1340":[163],"for":[165,194,276],"23":[166],"targets":[168,309],"show":[170,182,238,281,302],"most":[172],"correlate":[174],"with":[175,213,261],"each":[176,277],"other.":[177],"Most":[178],"pairs":[179],"coefficient":[185],"about":[187,247],"0.5.":[188],"The":[189],"slightly":[192,256],"higher":[193],"similar":[197],"types.":[198],"found":[200],"significant":[203],"problem":[204],"when":[205,271],"developing":[206],"deal":[212],"proteins":[214],"length.":[217],"Also":[218],"comparisons":[220],"complicated":[225],"many":[227],"are":[229],"dependent":[230,267,355],"on":[231],"size":[233],"target.":[236,278],"manual":[241,311,336],"assessment":[242],"reproduced":[245],"70%":[248],"using":[249,283],"Alignment":[252],"independent":[253,352],"measures,":[254,356],"detects":[255],"more":[257],"correct":[263],"fold,":[264],"while":[265],"alignment":[266,351,354],"agree":[269],"selecting":[272],"best":[274,342],"Finally":[279],"would,":[286],"large":[289],"extent,":[290],"reproduce":[291,328],"assessors":[293],"ranking":[294],"at":[298,321],"CASP3.":[299,322],"CONCLUSIONS:":[300],"given":[304,317],"sufficient":[306],"number":[307],"would":[315],"almost":[318],"identical":[319],"results":[320],"If":[323],"intent":[325],"scoring":[332],"done":[333],"by":[334],"assessor":[337],"CASP3,":[340],"approach":[343],"might":[344],"combination":[349],"recent":[361],"studies.":[362]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":6}],"updated_date":"2026-08-04T08:18:43.703281","created_date":"2025-10-10T00:00:00"}