{"id":"https://openalex.org/W2265655986","doi":"https://doi.org/10.1186/1471-2105-16-s18-s15","title":"Condensing Raman spectrum for single-cell phenotype analysis","display_name":"Condensing Raman spectrum for single-cell phenotype analysis","publication_year":2015,"publication_date":"2015-12-01","ids":{"openalex":"https://openalex.org/W2265655986","doi":"https://doi.org/10.1186/1471-2105-16-s18-s15","mag":"2265655986","pmid":"https://pubmed.ncbi.nlm.nih.gov/26681607"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-16-s18-s15","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-16-s18-s15","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-16-S18-S15","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-16-S18-S15","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108903761","display_name":"Shiwei Sun","orcid":"https://orcid.org/0000-0002-0351-3720"},"institutions":[{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shiwei Sun","raw_affiliation_strings":["Key Lab of Intelligent Information Processing, Institute of Computing Technology of the Chinese Academy of Sciences, 100190, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Information Processing, Institute of Computing Technology of the Chinese Academy of Sciences, 100190, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101480047","display_name":"Xuetao Wang","orcid":"https://orcid.org/0000-0002-9743-4678"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210158139","display_name":"Qingdao Institute of Bioenergy and Bioprocess Technology","ror":"https://ror.org/05h3vcy91","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158139"]},{"id":"https://openalex.org/I4210161003","display_name":"Qingdao Center of Resource Chemistry and New Materials","ror":"https://ror.org/05x85k702","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210089297","https://openalex.org/I4210161003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuetao Wang","raw_affiliation_strings":["CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","CUDA Research Centre of Qingdao, Qingdao, 266101, Shandong, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","institution_ids":["https://openalex.org/I4210158139","https://openalex.org/I19820366"]},{"raw_affiliation_string":"CUDA Research Centre of Qingdao, Qingdao, 266101, Shandong, China","institution_ids":["https://openalex.org/I4210161003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100618900","display_name":"Xin Gao","orcid":"https://orcid.org/0000-0002-7108-3574"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Xin Gao","raw_affiliation_strings":["Computational Bioscience Research Center, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia"],"affiliations":[{"raw_affiliation_string":"Computational Bioscience Research Center, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078519435","display_name":"Lihui Ren","orcid":"https://orcid.org/0000-0001-6413-0064"},"institutions":[{"id":"https://openalex.org/I4210158139","display_name":"Qingdao Institute of Bioenergy and Bioprocess Technology","ror":"https://ror.org/05h3vcy91","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158139"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lihui Ren","raw_affiliation_strings":["CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","institution_ids":["https://openalex.org/I4210158139","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042843762","display_name":"Xiaoquan Su","orcid":"https://orcid.org/0000-0003-2144-1991"},"institutions":[{"id":"https://openalex.org/I4210158139","display_name":"Qingdao Institute of Bioenergy and Bioprocess Technology","ror":"https://ror.org/05h3vcy91","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158139"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoquan Su","raw_affiliation_strings":["CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","institution_ids":["https://openalex.org/I4210158139","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076729236","display_name":"Dongbo Bu","orcid":"https://orcid.org/0000-0003-4119-4238"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongbo Bu","raw_affiliation_strings":["Key Lab of Intelligent Information Processing, Institute of Computing Technology of the Chinese Academy of Sciences, 100190, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Information Processing, Institute of Computing Technology of the Chinese Academy of Sciences, 100190, Beijing, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076346443","display_name":"Kang Ning","orcid":"https://orcid.org/0000-0003-3325-5387"},"institutions":[{"id":"https://openalex.org/I4210158139","display_name":"Qingdao Institute of Bioenergy and Bioprocess Technology","ror":"https://ror.org/05h3vcy91","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158139"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210161003","display_name":"Qingdao Center of Resource Chemistry and New Materials","ror":"https://ror.org/05x85k702","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210089297","https://openalex.org/I4210161003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kang Ning","raw_affiliation_strings":["CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","CUDA Research Centre of Qingdao, Qingdao, 266101, Shandong, China","College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Bioinformatics Group of Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, Shandong, P. R., China","institution_ids":["https://openalex.org/I4210158139","https://openalex.org/I19820366"]},{"raw_affiliation_string":"CUDA Research Centre of Qingdao, Qingdao, 266101, Shandong, China","institution_ids":["https://openalex.org/I4210161003"]},{"raw_affiliation_string":"College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5108903761"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":4.561,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.94279562,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"16","issue":"S18","first_page":"S15","last_page":"S15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.7047756314277649},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5707350969314575},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.48147645592689514},{"id":"https://openalex.org/keywords/single-cell-analysis","display_name":"Single-cell analysis","score":0.4157450497150421},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.40973758697509766},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.40463632345199585},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37710532546043396},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3524366021156311},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34361228346824646},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11427977681159973},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08124005794525146}],"concepts":[{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.7047756314277649},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5707350969314575},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.48147645592689514},{"id":"https://openalex.org/C2776950831","wikidata":"https://www.wikidata.org/wiki/Q15635432","display_name":"Single-cell analysis","level":3,"score":0.4157450497150421},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40973758697509766},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.40463632345199585},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37710532546043396},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3524366021156311},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34361228346824646},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11427977681159973},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08124005794525146}],"mesh":[{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016002","descriptor_name":"Discriminant Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016002","descriptor_name":"Discriminant Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016002","descriptor_name":"Discriminant Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-16-s18-s15","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-16-s18-s15","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-16-S18-S15","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26681607","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26681607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:3660366","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4682421","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:ir.qibebt.ac.cn:337004/7915","is_oa":false,"landing_page_url":"http://ir.qibebt.ac.cn/handle/337004/7915","pdf_url":null,"source":{"id":"https://openalex.org/S4306400842","display_name":"Institutional knowledge base (Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I19820366","host_organization_name":"Chinese Academy of Sciences","host_organization_lineage":["https://openalex.org/I19820366"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"\u671f\u520a\u8bba\u6587"},{"id":"pmh:oai:repository.kaust.edu.sa:10754/593294","is_oa":true,"landing_page_url":"http://hdl.handle.net/10754/593294","pdf_url":null,"source":{"id":"https://openalex.org/S4306401596","display_name":"King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71920554","host_organization_name":"King Abdullah University of Science and Technology","host_organization_lineage":["https://openalex.org/I71920554"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-16-s18-s15","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-16-s18-s15","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-16-S18-S15","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land","score":0.75}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1828425977","display_name":null,"funder_award_id":"973 Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G271225352","display_name":null,"funder_award_id":"3127083","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3077928441","display_name":null,"funder_award_id":"31271410","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G35433928","display_name":null,"funder_award_id":"61103167","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3888631583","display_name":null,"funder_award_id":"61272318","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6258415954","display_name":null,"funder_award_id":"Chinese","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G636961877","display_name":null,"funder_award_id":"61303161","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6686995610","display_name":null,"funder_award_id":"2014A","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7129907147","display_name":null,"funder_award_id":"(973 Program","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7814778640","display_name":null,"funder_award_id":"31270834","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G795020757","display_name":null,"funder_award_id":"2012CB316502","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"},{"id":"https://openalex.org/F4320326177","display_name":"Chinesisch-Deutsche Zentrum f\u00fcr Wissenschaftsf\u00f6rderung","ror":"https://ror.org/03ny8r668"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2265655986.pdf","grobid_xml":"https://content.openalex.org/works/W2265655986.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1243254526","https://openalex.org/W1575777508","https://openalex.org/W1983269914","https://openalex.org/W1985676839","https://openalex.org/W1997712011","https://openalex.org/W2015886346","https://openalex.org/W2021644514","https://openalex.org/W2026078372","https://openalex.org/W2031940127","https://openalex.org/W2042074642","https://openalex.org/W2042704577","https://openalex.org/W2044058396","https://openalex.org/W2051850218","https://openalex.org/W2054921258","https://openalex.org/W2055335745","https://openalex.org/W2055398959","https://openalex.org/W2065311323","https://openalex.org/W2087242711","https://openalex.org/W2091998550","https://openalex.org/W2114176419","https://openalex.org/W2123089842","https://openalex.org/W2133181568","https://openalex.org/W2144629166","https://openalex.org/W2167046694","https://openalex.org/W2167877584","https://openalex.org/W2168593414","https://openalex.org/W2171280873","https://openalex.org/W2387072577","https://openalex.org/W4301966137","https://openalex.org/W4392468778"],"related_works":["https://openalex.org/W2041783360","https://openalex.org/W2930001795","https://openalex.org/W2415013816","https://openalex.org/W4229068595","https://openalex.org/W3013151148","https://openalex.org/W4231548908","https://openalex.org/W4247819660","https://openalex.org/W2975378934","https://openalex.org/W3104133195","https://openalex.org/W2781745374"],"abstract_inverted_index":{"In":[0,40,60],"this":[1],"work,":[2],"we":[3],"have":[4],"proposed":[5],"an":[6],"approach":[7,29],"called":[8],"rDisc":[9,139],"to":[10,48,68,84,90,106,109,142],"discretize":[11],"the":[12,37,61,71,77,98,119,131],"original":[13,38],"Raman":[14,72,116],"spectrum":[15,111,121,129],"into":[16],"only":[17],"a":[18,127],"few":[19],"(usually":[20],"less":[21],"than":[22,114],"20)":[23],"representative":[24,64],"peaks":[25,65,79],"(Raman":[26],"shifts).":[27],"The":[28],"has":[30],"advantages":[31],"in":[32],"removing":[33],"noises,":[34],"and":[35,57,93,130],"condensing":[36],"spectrum.":[39],"particular,":[41],"effective":[42],"signal":[43,58],"processing":[44,132],"procedures":[45],"were":[46,66],"designed":[47],"eliminate":[49],"noise,":[50],"utilising":[51],"wavelet":[52],"transform":[53],"denoising,":[54],"baseline":[55],"correction,":[56],"normalization.":[59],"discretizing":[62],"process,":[63],"selected":[67,78],"signicantly":[69],"decrease":[70],"data":[73],"size.":[74],"More":[75],"importantly,":[76],"are":[80],"chosen":[81],"as":[82,86],"suitable":[83],"serve":[85],"key":[87],"biological":[88],"markers":[89],"differentiate":[91],"species":[92],"other":[94,143],"cellular":[95],"features.":[96],"Additionally,":[97],"classication":[99],"performance":[100],"of":[101,126],"discretized":[102,120],"spectra":[103],"was":[104],"found":[105],"be":[107],"comparable":[108],"full":[110,128],"having":[112],"more":[113],"1000":[115],"shifts.":[117],"Overall,":[118],"needs":[122],"about":[123],"5storage":[124],"space":[125],"speed":[133],"is":[134],"considerably":[135],"faster.":[136],"This":[137],"makes":[138],"clearly":[140],"superior":[141],"methods":[144],"for":[145],"single-cell":[146],"classication.":[147]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}