{"id":"https://openalex.org/W1993563914","doi":"https://doi.org/10.1186/1471-2105-15-s10-p17","title":"Building a knowledge base to assist clinical decision-making using the Pediatric Research Database (PRD) and machine learning: a case study on pediatric asthma patients","display_name":"Building a knowledge base to assist clinical decision-making using the Pediatric Research Database (PRD) and machine learning: a case study on pediatric asthma patients","publication_year":2014,"publication_date":"2014-09-29","ids":{"openalex":"https://openalex.org/W1993563914","doi":"https://doi.org/10.1186/1471-2105-15-s10-p17","mag":"1993563914"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-15-s10-p17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-s10-p17","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-S10-P17","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-S10-P17","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090177748","display_name":"Naga Satya V Rao Nagisetty","orcid":"https://orcid.org/0000-0002-9079-4179"},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Naga Nagisetty","raw_affiliation_strings":["Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025258985","display_name":"Eunice Y. Huang","orcid":"https://orcid.org/0000-0003-1413-7860"},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eunice Y Huang","raw_affiliation_strings":["Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003605455","display_name":"G WADE","orcid":null},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grady Wade","raw_affiliation_strings":["Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066901628","display_name":"Teeradache Viangteeravat","orcid":"https://orcid.org/0000-0002-1337-1762"},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teeradache Viangteeravat","raw_affiliation_strings":["Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Core, Children\u2019s Foundation Research Institute, Memphis, TN, 38103, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA","institution_ids":["https://openalex.org/I160606119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090177748"],"corresponding_institution_ids":["https://openalex.org/I160606119"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.3125,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.60930493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"15","issue":"S10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12205","display_name":"Time Series Analysis and Forecasting","score":0.9509000182151794,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12205","display_name":"Time Series Analysis and Forecasting","score":0.9509000182151794,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/knowledge-base","display_name":"Knowledge base","score":0.5894373655319214},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5675686597824097},{"id":"https://openalex.org/keywords/asthma","display_name":"Asthma","score":0.4766831398010254},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4359613358974457},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3975751996040344},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.37122011184692383},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3662733733654022},{"id":"https://openalex.org/keywords/knowledge-management","display_name":"Knowledge management","score":0.35937249660491943},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3370460569858551},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.10090595483779907}],"concepts":[{"id":"https://openalex.org/C4554734","wikidata":"https://www.wikidata.org/wiki/Q593744","display_name":"Knowledge base","level":2,"score":0.5894373655319214},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5675686597824097},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.4766831398010254},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4359613358974457},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3975751996040344},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37122011184692383},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3662733733654022},{"id":"https://openalex.org/C56739046","wikidata":"https://www.wikidata.org/wiki/Q192060","display_name":"Knowledge management","level":1,"score":0.35937249660491943},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3370460569858551},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10090595483779907}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/1471-2105-15-s10-p17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-s10-p17","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-S10-P17","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4196036","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4196036","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-15-s10-p17","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-s10-p17","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-S10-P17","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.5299999713897705}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1993563914.pdf","grobid_xml":"https://content.openalex.org/works/W1993563914.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W1722431364","https://openalex.org/W2022460880","https://openalex.org/W2133315251"],"related_works":["https://openalex.org/W1075988649","https://openalex.org/W4382298417","https://openalex.org/W2763069634","https://openalex.org/W2395336337","https://openalex.org/W1524220139","https://openalex.org/W2791729113","https://openalex.org/W2792401660","https://openalex.org/W2343770041","https://openalex.org/W2035331892","https://openalex.org/W1967695580"],"abstract_inverted_index":{"Background":[0],"The":[1],"Pediatric":[2],"Research":[3],"Database":[4],"(PRD)":[5],"is":[6,65,99],"a":[7,57,66],"clinically":[8],"rich":[9],"de-identified,":[10],"standardized":[11],"database":[12],"designed":[13],"around":[14],"our":[15],"institution\u2019s":[16],"electronic":[17],"medical":[18],"record":[19],"(EMR)":[20],"system.":[21],"We":[22],"intend":[23],"to":[24,31,110,119,133],"expand":[25],"the":[26,29,86],"utilization":[27],"of":[28,50,74,79],"PRD":[30],"assist":[32],"physicians":[33],"by":[34,128],"providing":[35],"historical":[36],"patterns":[37,136],"based":[38],"on":[39],"conversations":[40],"among":[41],"physicians,":[42],"patients":[43,75,92],"and":[44,101,137],"research":[45],"personnel.":[46],"As":[47],"an":[48],"example":[49],"such":[51,91,123],"implementation,":[52],"we":[53],"are":[54],"currently":[55],"using":[56],"prevalent,":[58],"chronic":[59],"respiratory":[60],"disease,":[61],"i.e.,":[62],"asthma.":[63],"Asthma":[64],"very":[67,102],"common":[68],"disease":[69],"in":[70],"children.":[71],"Early":[72],"identification":[73],"at":[76],"high":[77],"risk":[78],"developing":[80],"asthma":[81],"can":[82],"help":[83],"provide":[84,141],"them":[85],"best":[87],"possible":[88],"treatment.":[89],"Identifying":[90],"from":[93,112],"huge":[94],"data":[95,106],"sets":[96],"(e.g.,":[97],"EMRs)":[98],"challenging":[100],"time":[103],"consuming.":[104],"Using":[105],"mining":[107],"techniques":[108],"[1-3]":[109],"learn":[111],"past":[113],"examples":[114],"not":[115],"only":[116],"permits":[117],"researchers":[118],"detect":[120],"expected":[121],"events,":[122],"as":[124],"might":[125],"be":[126],"predicted":[127],"models,":[129],"but":[130],"also":[131],"helps":[132],"discover":[134],"unexpected":[135],"relationships":[138],"that":[139],"may":[140],"new":[142],"insights.":[143]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2025-10-10T00:00:00"}