{"id":"https://openalex.org/W2100294785","doi":"https://doi.org/10.1186/1471-2105-15-45","title":"DFLAT: functional annotation for human development","display_name":"DFLAT: functional annotation for human development","publication_year":2014,"publication_date":"2014-02-07","ids":{"openalex":"https://openalex.org/W2100294785","doi":"https://doi.org/10.1186/1471-2105-15-45","mag":"2100294785","pmid":"https://pubmed.ncbi.nlm.nih.gov/24507166"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-15-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-45","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-45","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-45","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033769222","display_name":"Heather C. Wick","orcid":null},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Heather C Wick","raw_affiliation_strings":["Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA. hwick@cs.tufts.edu","Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA. hwick@cs.tufts.edu","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006288716","display_name":"Harold Drabkin","orcid":"https://orcid.org/0000-0003-2689-5511"},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harold Drabkin","raw_affiliation_strings":["Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA","Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]},{"raw_affiliation_string":"Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010047950","display_name":"Huy Ngu","orcid":null},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huy Ngu","raw_affiliation_strings":["Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065643028","display_name":"Michael Sackman","orcid":null},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Sackman","raw_affiliation_strings":["Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014327874","display_name":"Craig Fournier","orcid":null},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig Fournier","raw_affiliation_strings":["Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069291825","display_name":"Jessica Haggett","orcid":null},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Haggett","raw_affiliation_strings":["Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA 02155, USA","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Department of Computer Science, Tufts University, 155 College Ave, Medford, MA, 02155, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016349593","display_name":"Judith A. Blake","orcid":"https://orcid.org/0000-0001-8522-334X"},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judith A Blake","raw_affiliation_strings":["Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA","Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA","institution_ids":["https://openalex.org/I4210115256"]},{"raw_affiliation_string":"Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA","institution_ids":["https://openalex.org/I4210115256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081715355","display_name":"Diana W. Bianchi","orcid":"https://orcid.org/0000-0001-9270-5267"},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana W Bianchi","raw_affiliation_strings":["Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074883462","display_name":"Donna K. Slonim","orcid":"https://orcid.org/0000-0003-3357-437X"},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna K Slonim","raw_affiliation_strings":["Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA","institution_ids":["https://openalex.org/I121934306"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033769222"],"corresponding_institution_ids":["https://openalex.org/I121934306"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.5595,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.82634731,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"45","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.2363000065088272,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.2363000065088272,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.1404000073671341,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.12330000102519989,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6911978125572205},{"id":"https://openalex.org/keywords/functional-genomics","display_name":"Functional genomics","score":0.6138932108879089},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5718593001365662},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5603992342948914},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5457838773727417},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4917159676551819},{"id":"https://openalex.org/keywords/gene-annotation","display_name":"Gene Annotation","score":0.44880443811416626},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.4455040991306305},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4204850196838379},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.42033258080482483},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.37984490394592285},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3419830799102783},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.33519017696380615},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33103442192077637},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.2760544717311859}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6911978125572205},{"id":"https://openalex.org/C161078062","wikidata":"https://www.wikidata.org/wiki/Q1068690","display_name":"Functional genomics","level":5,"score":0.6138932108879089},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5718593001365662},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5603992342948914},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5457838773727417},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4917159676551819},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.44880443811416626},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.4455040991306305},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4204850196838379},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.42033258080482483},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37984490394592285},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3419830799102783},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.33519017696380615},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33103442192077637},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2760544717311859},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000653","descriptor_name":"Amniotic Fluid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000653","descriptor_name":"Amniotic Fluid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000653","descriptor_name":"Amniotic Fluid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006803","descriptor_name":"Human Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006803","descriptor_name":"Human Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006803","descriptor_name":"Human Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047109","descriptor_name":"Fetal Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047109","descriptor_name":"Fetal Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047109","descriptor_name":"Fetal Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-15-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-45","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-45","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:24507166","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24507166","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:2911421","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3928322","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:mouseion.jax.org:stfb2014-1035","is_oa":false,"landing_page_url":"https://mouseion.jax.org/stfb2014/34","pdf_url":null,"source":{"id":"https://openalex.org/S4377196421","display_name":"The Mouseion at the JAXlibrary (Jackson Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210115256","host_organization_name":"Jackson Laboratory","host_organization_lineage":["https://openalex.org/I4210115256"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Research 2014","raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3928322","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3928322","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-15-45","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-45","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-45","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.46000000834465027,"display_name":"Partnerships for the goals"}],"awards":[{"id":"https://openalex.org/G2462819461","display_name":null,"funder_award_id":"R01HD058880","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2636907518","display_name":null,"funder_award_id":"R01HD076140","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2745823948","display_name":null,"funder_award_id":"R01HD058880","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G2820513190","display_name":null,"funder_award_id":"U41 HG002273","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G7171154341","display_name":null,"funder_award_id":"R01HD076140","funder_id":"https://openalex.org/F4320337364","funder_display_name":"National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7329624422","display_name":null,"funder_award_id":"R01HD076140","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7707716316","display_name":null,"funder_award_id":"R01 HD076140","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G8601328650","display_name":null,"funder_award_id":"P30 CA034196","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G958130886","display_name":null,"funder_award_id":"R01 HD058880","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320314070","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337364","display_name":"National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2100294785.pdf","grobid_xml":"https://content.openalex.org/works/W2100294785.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W30971957","https://openalex.org/W1236321187","https://openalex.org/W1559989352","https://openalex.org/W1607914109","https://openalex.org/W1757269241","https://openalex.org/W1806630989","https://openalex.org/W1921455865","https://openalex.org/W1966897977","https://openalex.org/W1967832563","https://openalex.org/W1971118100","https://openalex.org/W1977958433","https://openalex.org/W1982266611","https://openalex.org/W1983339463","https://openalex.org/W1985695385","https://openalex.org/W1991017526","https://openalex.org/W1998902445","https://openalex.org/W2001722118","https://openalex.org/W2019151212","https://openalex.org/W2020859582","https://openalex.org/W2024210326","https://openalex.org/W2027647323","https://openalex.org/W2032337062","https://openalex.org/W2038243095","https://openalex.org/W2039527405","https://openalex.org/W2040557030","https://openalex.org/W2045220705","https://openalex.org/W2060228768","https://openalex.org/W2070872186","https://openalex.org/W2078052907","https://openalex.org/W2091077369","https://openalex.org/W2096525273","https://openalex.org/W2098102754","https://openalex.org/W2103017472","https://openalex.org/W2107521571","https://openalex.org/W2108172198","https://openalex.org/W2112085178","https://openalex.org/W2120024428","https://openalex.org/W2122084873","https://openalex.org/W2122683221","https://openalex.org/W2129099812","https://openalex.org/W2130410032","https://openalex.org/W2134067693","https://openalex.org/W2134582937","https://openalex.org/W2135230352","https://openalex.org/W2138255346","https://openalex.org/W2141790847","https://openalex.org/W2144067971","https://openalex.org/W2149501457","https://openalex.org/W2158965525","https://openalex.org/W2159030941","https://openalex.org/W2161771297","https://openalex.org/W2166939868","https://openalex.org/W2167119716","https://openalex.org/W2214495651","https://openalex.org/W2399356828","https://openalex.org/W2402201054","https://openalex.org/W2605068739","https://openalex.org/W4230784961","https://openalex.org/W4240605225"],"related_works":["https://openalex.org/W2901823680","https://openalex.org/W2059565715","https://openalex.org/W1999129612","https://openalex.org/W2116418175","https://openalex.org/W2009940763","https://openalex.org/W2126804125","https://openalex.org/W2946410450","https://openalex.org/W4361192415","https://openalex.org/W2137318037","https://openalex.org/W2020634034"],"abstract_inverted_index":{"BACKGROUND:":[0],"Recent":[1],"increases":[2,251],"in":[3,57,67,95,145,176,199,207],"genomic":[4,311],"studies":[5,312],"of":[6,21,25,62,73,113,115,148,157,171,205,244,254,263,272,313],"the":[7,22,46,60,70,96,111,140,177,190,238,248,252,259,270,278,294],"developing":[8],"human":[9,78,97,123,149,314],"fetus":[10],"and":[11,37,80,119,130,143,220,225,236,301,316],"neonate":[12],"have":[13],"led":[14],"to":[15,59,91,109,139,305,309],"a":[16,35,154],"need":[17],"for":[18,40,52,77,88,197,290],"widespread":[19],"characterization":[20],"functional":[23,49,158,299],"roles":[24],"genes":[26,79],"at":[27,104],"different":[28],"developmental":[29,86,167],"stages.":[30],"The":[31,100],"Gene":[32,202],"Ontology":[33],"(GO),":[34],"valuable":[36,164],"widely-used":[38],"resource":[39],"characterizing":[41],"gene":[42,81,93,117,125,172,256,284,302],"function,":[43],"offers":[44],"perhaps":[45],"most":[47],"suitable":[48],"annotation":[50,159,250,300],"system":[51],"this":[53],"purpose.":[54],"However,":[55],"due":[56],"part":[58],"difficulty":[61],"studying":[63],"molecular":[64],"genetic":[65],"effects":[66],"humans,":[68],"even":[69],"current":[71,264],"collection":[72,170],"comprehensive":[74],"GO":[75,132,141,146,187],"annotations":[76,135,188],"products":[82],"often":[83],"lacks":[84],"adequate":[85],"context":[87],"scientists":[89],"wishing":[90],"study":[92],"function":[94,179],"fetus.":[98],"DESCRIPTION:":[99],"Developmental":[101],"FunctionaL":[102],"Annotation":[103],"Tufts":[105],"(DFLAT)":[106],"project":[107,296],"aims":[108],"improve":[110],"quality":[112],"analyses":[114,204],"fetal":[116,124,315],"expression":[118,206,245],"regulation":[120],"by":[121,184],"curating":[122],"functions":[126],"using":[127,247],"both":[128,234],"manual":[129],"semi-automated":[131],"procedures.":[133],"Eligible":[134],"are":[136],"then":[137],"contributed":[138],"database":[142],"included":[144],"releases":[147],"data.":[150],"DFLAT":[151,193,239,249,279,295],"has":[152],"produced":[153],"considerable":[155],"body":[156],"that":[160],"we":[161],"demonstrate":[162],"provides":[163],"information":[165],"about":[166],"genomics.":[168],"A":[169],"sets":[173,285,303],"(genes":[174],"implicated":[175,255,282],"same":[178],"or":[180],"biological":[181],"process),":[182],"made":[183],"combining":[185],"existing":[186],"with":[189,217,229,235,277],"13,344":[191],"new":[192,298],"annotations,":[194],"is":[195],"available":[196],"use":[198],"novel":[200],"analyses.":[201],"set":[203],"several":[208],"data":[209,246],"sets,":[210,257],"including":[211],"amniotic":[212],"fluid":[213],"RNA":[214],"from":[215,227],"fetuses":[216],"trisomies":[218],"21":[219],"18,":[221],"umbilical":[222],"cord":[223],"blood,":[224],"blood":[226],"newborns":[228],"bronchopulmonary":[230],"dysplasia,":[231],"were":[232],"conducted":[233],"without":[237],"annotation.":[240],"CONCLUSIONS:":[241],"Functional":[242],"analysis":[243],"number":[253],"reflecting":[258],"DFLAT's":[260],"improved":[261],"representation":[262],"knowledge.":[265],"Blinded":[266],"literature":[267],"review":[268],"supports":[269],"validity":[271],"newly":[273],"significant":[274,283],"findings":[275],"obtained":[276],"annotations.":[280],"Newly":[281],"also":[286],"suggest":[287],"specific":[288],"hypotheses":[289],"future":[291],"research.":[292],"Overall,":[293],"contributes":[297],"likely":[304],"enhance":[306],"our":[307],"ability":[308],"interpret":[310],"neonatal":[317],"development.":[318]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}