{"id":"https://openalex.org/W2006981549","doi":"https://doi.org/10.1186/1471-2105-15-28","title":"Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data","display_name":"Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data","publication_year":2014,"publication_date":"2014-01-27","ids":{"openalex":"https://openalex.org/W2006981549","doi":"https://doi.org/10.1186/1471-2105-15-28","mag":"2006981549","pmid":"https://pubmed.ncbi.nlm.nih.gov/24467687"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-15-28","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-28","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-28","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-28","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109244760","display_name":"Charles N. Cole","orcid":null},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Charles Cole","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035580767","display_name":"Konstantinos Krampis","orcid":"https://orcid.org/0000-0002-9155-2390"},"institutions":[{"id":"https://openalex.org/I1301553790","display_name":"J. Craig Venter Institute","ror":"https://ror.org/049r1ts75","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1301553790"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konstantinos Krampis","raw_affiliation_strings":["J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD, 20850, USA","J. Craig Venter Institute,Rockville,USA"],"affiliations":[{"raw_affiliation_string":"J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD, 20850, USA","institution_ids":["https://openalex.org/I1301553790"]},{"raw_affiliation_string":"J. Craig Venter Institute,Rockville,USA","institution_ids":["https://openalex.org/I1301553790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026379467","display_name":"Konstantinos Karagiannis","orcid":"https://orcid.org/0000-0002-4776-5137"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konstantinos Karagiannis","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012322429","display_name":"Jonas S. Almeida","orcid":"https://orcid.org/0000-0002-7883-7922"},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonas S Almeida","raw_affiliation_strings":["Division of Informatics of the Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA","Division of Informatics of the Department of Pathology, University of Alabama at Birmingham, Birmingham, USA"],"affiliations":[{"raw_affiliation_string":"Division of Informatics of the Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Division of Informatics of the Department of Pathology, University of Alabama at Birmingham, Birmingham, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060033844","display_name":"William J. Faison","orcid":null},"institutions":[{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]},{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William J Faison","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042853916","display_name":"Mona Motwani","orcid":"https://orcid.org/0000-0003-0912-5478"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mona Motwani","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100621587","display_name":"Quan Wan","orcid":"https://orcid.org/0000-0003-4289-3487"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quan Wan","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061978409","display_name":"Anton Golikov","orcid":null},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1318287680","display_name":"Center for Biologics Evaluation and Research","ror":"https://ror.org/02nr3fr97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1318287680","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anton Golikov","raw_affiliation_strings":["Center for Biologics Evaluation and Research, US Food and Drug Administration, 1451 Rockville Pike, HFM-470, Rockville, MD, 20852, USA","Center for Biologics Evaluation and Research, US Food & Drug Administration, Rockville, USA"],"affiliations":[{"raw_affiliation_string":"Center for Biologics Evaluation and Research, US Food and Drug Administration, 1451 Rockville Pike, HFM-470, Rockville, MD, 20852, USA","institution_ids":["https://openalex.org/I1318287680","https://openalex.org/I1320320070"]},{"raw_affiliation_string":"Center for Biologics Evaluation and Research, US Food & Drug Administration, Rockville, USA","institution_ids":["https://openalex.org/I1318287680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002239035","display_name":"Yang Pan","orcid":"https://orcid.org/0000-0003-3487-7233"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Pan","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, 20037, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035615708","display_name":"Vahan Simonyan","orcid":"https://orcid.org/0000-0002-4868-4785"},"institutions":[{"id":"https://openalex.org/I1318287680","display_name":"Center for Biologics Evaluation and Research","ror":"https://ror.org/02nr3fr97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1318287680","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vahan Simonyan","raw_affiliation_strings":["Center for Biologics Evaluation and Research, US Food and Drug Administration, 1451 Rockville Pike, HFM-470, Rockville, MD, 20852, USA","Center for Biologics Evaluation and Research, US Food & Drug Administration, Rockville, USA"],"affiliations":[{"raw_affiliation_string":"Center for Biologics Evaluation and Research, US Food and Drug Administration, 1451 Rockville Pike, HFM-470, Rockville, MD, 20852, USA","institution_ids":["https://openalex.org/I1318287680","https://openalex.org/I1320320070"]},{"raw_affiliation_string":"Center for Biologics Evaluation and Research, US Food & Drug Administration, Rockville, USA","institution_ids":["https://openalex.org/I1318287680"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020517234","display_name":"Raja Mazumder","orcid":"https://orcid.org/0000-0001-8823-9945"},"institutions":[{"id":"https://openalex.org/I4210104270","display_name":"McCormick (United States)","ror":"https://ror.org/01ftbgh03","country_code":"US","type":"company","lineage":["https://openalex.org/I4210104270"]},{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]},{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raja Mazumder","raw_affiliation_strings":["Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC 20037, USA. mazumder@gwu.edu","Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","McCormick Genomic and Proteomic Center, George Washington University, Washington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC 20037, USA. mazumder@gwu.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, USA","institution_ids":["https://openalex.org/I4210135078","https://openalex.org/I193531525"]},{"raw_affiliation_string":"McCormick Genomic and Proteomic Center, George Washington University, Washington, USA","institution_ids":["https://openalex.org/I193531525","https://openalex.org/I4210104270"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5109244760"],"corresponding_institution_ids":["https://openalex.org/I193531525","https://openalex.org/I4210135078"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.5686,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.82178716,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"28","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.7553263902664185},{"id":"https://openalex.org/keywords/proteome","display_name":"Proteome","score":0.6179089546203613},{"id":"https://openalex.org/keywords/metadata","display_name":"Metadata","score":0.5819336175918579},{"id":"https://openalex.org/keywords/human-proteome-project","display_name":"Human proteome project","score":0.5227944254875183},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.51856929063797},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.49520865082740784},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.4658772647380829},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.404946506023407},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3697330355644226},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.3061452805995941},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.30308419466018677},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.24221962690353394},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.20361751317977905},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15700340270996094},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13416236639022827}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.7553263902664185},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.6179089546203613},{"id":"https://openalex.org/C93518851","wikidata":"https://www.wikidata.org/wiki/Q180160","display_name":"Metadata","level":2,"score":0.5819336175918579},{"id":"https://openalex.org/C94795543","wikidata":"https://www.wikidata.org/wiki/Q3813754","display_name":"Human proteome project","level":4,"score":0.5227944254875183},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.51856929063797},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49520865082740784},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.4658772647380829},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.404946506023407},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3697330355644226},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.3061452805995941},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.30308419466018677},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.24221962690353394},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.20361751317977905},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15700340270996094},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13416236639022827}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035843","descriptor_name":"Biomedical Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035843","descriptor_name":"Biomedical Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035843","descriptor_name":"Biomedical Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/1471-2105-15-28","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-28","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-28","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:24467687","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24467687","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:2901680","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3916084","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-15-28","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-28","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-28","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5843291493","display_name":null,"funder_award_id":"U01 CA168926","funder_id":"https://openalex.org/F4320309515","funder_display_name":"George Washington University"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320309515","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"},{"id":"https://openalex.org/F4320332382","display_name":"Oak Ridge Institute for Science and Education","ror":"https://ror.org/0526p1y61"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2006981549.pdf","grobid_xml":"https://content.openalex.org/works/W2006981549.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W1483023618","https://openalex.org/W1488799774","https://openalex.org/W1522653452","https://openalex.org/W1578830280","https://openalex.org/W1813746194","https://openalex.org/W1829312150","https://openalex.org/W1923384484","https://openalex.org/W1947762817","https://openalex.org/W1965917470","https://openalex.org/W1973878786","https://openalex.org/W1981224110","https://openalex.org/W1989717042","https://openalex.org/W1991579842","https://openalex.org/W1993167185","https://openalex.org/W1996181407","https://openalex.org/W1998712640","https://openalex.org/W1999930323","https://openalex.org/W2000401288","https://openalex.org/W2006077299","https://openalex.org/W2009302881","https://openalex.org/W2024872854","https://openalex.org/W2032354785","https://openalex.org/W2038595016","https://openalex.org/W2042103448","https://openalex.org/W2042160423","https://openalex.org/W2050525925","https://openalex.org/W2059282967","https://openalex.org/W2060880334","https://openalex.org/W2060932633","https://openalex.org/W2061849405","https://openalex.org/W2062926086","https://openalex.org/W2067082596","https://openalex.org/W2074754379","https://openalex.org/W2080097627","https://openalex.org/W2080310417","https://openalex.org/W2080902832","https://openalex.org/W2081843257","https://openalex.org/W2083730226","https://openalex.org/W2092550529","https://openalex.org/W2092741708","https://openalex.org/W2095355287","https://openalex.org/W2096525273","https://openalex.org/W2099589970","https://openalex.org/W2101735289","https://openalex.org/W2104570606","https://openalex.org/W2107768525","https://openalex.org/W2108234281","https://openalex.org/W2108366237","https://openalex.org/W2108754368","https://openalex.org/W2109372707","https://openalex.org/W2114044768","https://openalex.org/W2116398954","https://openalex.org/W2116623104","https://openalex.org/W2118284237","https://openalex.org/W2120944127","https://openalex.org/W2121906867","https://openalex.org/W2122982012","https://openalex.org/W2123179625","https://openalex.org/W2124985265","https://openalex.org/W2125353047","https://openalex.org/W2125789330","https://openalex.org/W2127136945","https://openalex.org/W2129137060","https://openalex.org/W2129828885","https://openalex.org/W2130982499","https://openalex.org/W2131563181","https://openalex.org/W2132560348","https://openalex.org/W2132632499","https://openalex.org/W2136482257","https://openalex.org/W2137015675","https://openalex.org/W2138155367","https://openalex.org/W2139549071","https://openalex.org/W2141885858","https://openalex.org/W2142892229","https://openalex.org/W2143238378","https://openalex.org/W2145234083","https://openalex.org/W2145307001","https://openalex.org/W2148083369","https://openalex.org/W2149441684","https://openalex.org/W2150297520","https://openalex.org/W2160168872","https://openalex.org/W2160581437","https://openalex.org/W2161241566","https://openalex.org/W2165446840","https://openalex.org/W2170675531","https://openalex.org/W2326879997","https://openalex.org/W2465449075","https://openalex.org/W4241091798","https://openalex.org/W4244606935","https://openalex.org/W4285719527","https://openalex.org/W4320301318"],"related_works":["https://openalex.org/W3092794487","https://openalex.org/W2094752534","https://openalex.org/W1982829397","https://openalex.org/W2885268310","https://openalex.org/W2106414650","https://openalex.org/W2347437365","https://openalex.org/W2025055488","https://openalex.org/W1999412725","https://openalex.org/W2575115220","https://openalex.org/W4390205769"],"abstract_inverted_index":{"Availability":[0],"of":[1,3,12],"thousands":[2],"sequenced":[4],"samples":[5],"from":[6],"patients":[7],"provides":[8],"a":[9],"rich":[10],"repository":[11],"sequence":[13],"information":[14],"that":[15],"can":[16],"be":[17],"utilized":[18],"to":[19],"identify":[20],"individual":[21],"level":[22],"SNVs":[23],"and":[24],"their":[25],"effect":[26],"on":[27],"the":[28,33],"human":[29],"proteome":[30],"beyond":[31],"what":[32],"dbSNP":[34],"database":[35],"provides.":[36]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}