{"id":"https://openalex.org/W2014419197","doi":"https://doi.org/10.1186/1471-2105-15-246","title":"Rapid screening for phenotype-genotype associations by linear transformations of genomic evaluations","display_name":"Rapid screening for phenotype-genotype associations by linear transformations of genomic evaluations","publication_year":2014,"publication_date":"2014-07-19","ids":{"openalex":"https://openalex.org/W2014419197","doi":"https://doi.org/10.1186/1471-2105-15-246","mag":"2014419197","pmid":"https://pubmed.ncbi.nlm.nih.gov/25038782"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-15-246","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-246","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-246","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-246","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062240904","display_name":"Jos\u00e9 Luis Gualdr\u00f3n Duarte","orcid":null},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"funder","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Jose L Gualdr\u00f3n Duarte","raw_affiliation_strings":["Departamento de Producci\u00f3n Animal, Facultad de Agronom\u00eda, UBA-CONICET, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Producci\u00f3n Animal, Facultad de Agronom\u00eda, UBA-CONICET, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I151201029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012156399","display_name":"R. J. C. Cantet","orcid":"https://orcid.org/0000-0001-6282-146X"},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"funder","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Rodolfo JC Cantet","raw_affiliation_strings":["Departamento de Producci\u00f3n Animal, Facultad de Agronom\u00eda, UBA-CONICET, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Producci\u00f3n Animal, Facultad de Agronom\u00eda, UBA-CONICET, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I151201029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008628295","display_name":"R. O. Bates","orcid":null},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald O Bates","raw_affiliation_strings":["Department of Animal Science, Michigan State University, East Lansing, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Michigan State University, East Lansing, MI, USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034296455","display_name":"Catherine W. Ernst","orcid":"https://orcid.org/0000-0003-2833-0995"},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine W Ernst","raw_affiliation_strings":["Department of Animal Science, Michigan State University, East Lansing, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Michigan State University, East Lansing, MI, USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072998859","display_name":"Nancy E. Raney","orcid":null},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy E Raney","raw_affiliation_strings":["Department of Animal Science, Michigan State University, East Lansing, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Michigan State University, East Lansing, MI, USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064864858","display_name":"Juan P. Steibel","orcid":"https://orcid.org/0000-0003-1725-2389"},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Juan P Steibel","raw_affiliation_strings":["Department of Animal Science, Michigan State University, East Lansing, MI, USA. steibelj@msu.edu","Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Michigan State University, East Lansing, MI, USA. steibelj@msu.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI, USA","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5064864858"],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":2.3258,"has_fulltext":true,"cited_by_count":80,"citation_normalized_percentile":{"value":0.88498128,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"246","last_page":"246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.8093000054359436,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.8093000054359436,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.12330000102519989,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11229","display_name":"Genetics and Plant Breeding","score":0.03530000150203705,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.5835878849029541},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4810052812099457},{"id":"https://openalex.org/keywords/variance","display_name":"Variance (accounting)","score":0.45954200625419617},{"id":"https://openalex.org/keywords/covariance","display_name":"Covariance","score":0.4556664526462555},{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.45464950799942017},{"id":"https://openalex.org/keywords/random-effects-model","display_name":"Random effects model","score":0.44646501541137695},{"id":"https://openalex.org/keywords/covariance-matrix","display_name":"Covariance matrix","score":0.4386865496635437},{"id":"https://openalex.org/keywords/multiple-comparisons-problem","display_name":"Multiple comparisons problem","score":0.4349166452884674},{"id":"https://openalex.org/keywords/mixed-model","display_name":"Mixed model","score":0.43248021602630615},{"id":"https://openalex.org/keywords/type-i-and-type-ii-errors","display_name":"Type I and type II errors","score":0.42082297801971436},{"id":"https://openalex.org/keywords/linear-model","display_name":"Linear model","score":0.41207700967788696},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.38582247495651245},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3777419626712799},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3207141160964966},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1342078149318695},{"id":"https://openalex.org/keywords/meta-analysis","display_name":"Meta-analysis","score":0.10889643430709839}],"concepts":[{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5835878849029541},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4810052812099457},{"id":"https://openalex.org/C196083921","wikidata":"https://www.wikidata.org/wiki/Q7915758","display_name":"Variance (accounting)","level":2,"score":0.45954200625419617},{"id":"https://openalex.org/C178650346","wikidata":"https://www.wikidata.org/wiki/Q201984","display_name":"Covariance","level":2,"score":0.4556664526462555},{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.45464950799942017},{"id":"https://openalex.org/C168743327","wikidata":"https://www.wikidata.org/wiki/Q1826427","display_name":"Random effects model","level":3,"score":0.44646501541137695},{"id":"https://openalex.org/C185142706","wikidata":"https://www.wikidata.org/wiki/Q1134404","display_name":"Covariance matrix","level":2,"score":0.4386865496635437},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.4349166452884674},{"id":"https://openalex.org/C16012445","wikidata":"https://www.wikidata.org/wiki/Q1501135","display_name":"Mixed model","level":2,"score":0.43248021602630615},{"id":"https://openalex.org/C40696583","wikidata":"https://www.wikidata.org/wiki/Q989120","display_name":"Type I and type II errors","level":2,"score":0.42082297801971436},{"id":"https://openalex.org/C163175372","wikidata":"https://www.wikidata.org/wiki/Q3339222","display_name":"Linear model","level":2,"score":0.41207700967788696},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.38582247495651245},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3777419626712799},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3207141160964966},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1342078149318695},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.10889643430709839},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001947","descriptor_name":"Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001947","descriptor_name":"Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001947","descriptor_name":"Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-15-246","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-246","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-246","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:25038782","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25038782","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4112210","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4112210","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/16317","is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/16317","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-15-246","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-15-246","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-15-246","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2261898272","display_name":null,"funder_award_id":"11-042","funder_id":"https://openalex.org/F4320310462","funder_display_name":"National Pork Board"},{"id":"https://openalex.org/G2439265903","display_name":null,"funder_award_id":"CONICET","funder_id":"https://openalex.org/F4320323257","funder_display_name":"Universidad de Buenos Aires"},{"id":"https://openalex.org/G3153070493","display_name":null,"funder_award_id":"2011-67015","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G3360244545","display_name":null,"funder_award_id":"20020100100861","funder_id":"https://openalex.org/F4320323257","funder_display_name":"Universidad de Buenos Aires"},{"id":"https://openalex.org/G3806601206","display_name":"Selecci\u00f3n gen\u00f3mica bajo desequilibrio de ligamiento, imputaci\u00f3n y tama\u00f1o efectivo.","funder_award_id":"11220120100621CO","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G4462417587","display_name":null,"funder_award_id":"11220120100621CO","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G5429253674","display_name":null,"funder_award_id":"2010-65205-20342","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G841842749","display_name":null,"funder_award_id":"2011-","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320310016","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993"},{"id":"https://openalex.org/F4320310462","display_name":"National Pork Board","ror":"https://ror.org/00safct20"},{"id":"https://openalex.org/F4320321594","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59"},{"id":"https://openalex.org/F4320323257","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"},{"id":"https://openalex.org/F4320332431","display_name":"College of Engineering, Michigan State University","ror":"https://ror.org/05hs6h993"},{"id":"https://openalex.org/F4320335478","display_name":"Secretar\u00eda de Ciencia y T\u00e9cnica, Universidad de Buenos Aires","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2014419197.pdf","grobid_xml":"https://content.openalex.org/works/W2014419197.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W36460117","https://openalex.org/W1523454857","https://openalex.org/W1928998639","https://openalex.org/W1968752557","https://openalex.org/W1977055616","https://openalex.org/W1980120336","https://openalex.org/W1980168725","https://openalex.org/W2002600206","https://openalex.org/W2017003869","https://openalex.org/W2021828797","https://openalex.org/W2023673366","https://openalex.org/W2031949967","https://openalex.org/W2046076301","https://openalex.org/W2049576543","https://openalex.org/W2064013109","https://openalex.org/W2067252216","https://openalex.org/W2067715889","https://openalex.org/W2071735562","https://openalex.org/W2077763475","https://openalex.org/W2077946779","https://openalex.org/W2091408025","https://openalex.org/W2091647341","https://openalex.org/W2095563328","https://openalex.org/W2113784410","https://openalex.org/W2118960339","https://openalex.org/W2127684760","https://openalex.org/W2134036574","https://openalex.org/W2141088880","https://openalex.org/W2149594592","https://openalex.org/W2153654037","https://openalex.org/W2156072758","https://openalex.org/W2160717298","https://openalex.org/W2161633633","https://openalex.org/W2164050502","https://openalex.org/W2170554520","https://openalex.org/W4300190830"],"related_works":["https://openalex.org/W154531455","https://openalex.org/W4239710992","https://openalex.org/W2020413892","https://openalex.org/W2113330311","https://openalex.org/W1891628293","https://openalex.org/W2903672469","https://openalex.org/W2102122784","https://openalex.org/W1551599973","https://openalex.org/W256699647","https://openalex.org/W2093463665"],"abstract_inverted_index":{"BACKGROUND:":[0],"Currently,":[1],"association":[2,63,325],"studies":[3],"are":[4,27,92,135,144,171],"analysed":[5],"using":[6,64,122,212,292,343],"statistical":[7],"mixed":[8,82],"models,":[9],"with":[10,109,182,260,271],"marker":[11,25,69,98,154,181,290],"effects":[12,26,86,228,236,262,291],"estimated":[13],"by":[14,138],"a":[15,44,49,59,81,88,119,126,157,230,257,268,273],"linear":[16],"transformation":[17],"of":[18,24,33,52,62,67,204,225,281,289,315,323,332],"genomic":[19,89,133,208,239,264,300],"breeding":[20,78,240,265],"values.":[21,241,266],"The":[22,101,180,242,286],"variances":[23],"needed":[28],"when":[29,342],"performing":[30],"the":[31,40,53,65,97,139,142,160,183,193,205,213,223,226,251,304,330],"tests":[32,151],"association.":[34,179],"However,":[35],"approaches":[36],"used":[37,172,221,320],"to":[38,95,111,118,147,173,248],"estimate":[39,51,96],"parameters":[41],"rely":[42],"on":[43,48],"prior":[45],"variance":[46,66,295],"or":[47],"constant":[50],"additive":[54,305],"variance.":[55,284],"Alternatively,":[56],"we":[57],"propose":[58],"standardized":[60,102,161,287],"test":[61,103,121,162,249,288],"each":[68,75,188],"effect,":[70],"which":[71,219],"generally":[72],"differ":[73],"among":[74],"other.":[76],"Random":[77],"values":[79],"from":[80,150,215,276],"model":[83,231,259],"including":[84],"fixed":[85,235,261],"and":[87,141,166,192,200,237,263,307],"covariance":[90],"matrix":[91,209],"linearly":[93],"transformed":[94],"effects.":[99],"RESULTS:":[100],"was":[104,129],"neither":[105],"conservative":[106],"nor":[107],"liberal":[108],"respect":[110],"type":[112],"I":[113],"error":[114],"rate":[115],"(false-positives),":[116],"compared":[117],"similar":[120],"Predictor":[123],"Error":[124],"Variance,":[125],"method":[127],"that":[128,232,336],"too":[130],"conservative.":[131],"Furthermore,":[132],"predictions":[134],"solved":[136],"efficiently":[137],"procedure,":[140],"p-values":[143],"virtually":[145],"identical":[146],"those":[148,216],"calculated":[149,211,247],"for":[152,250],"one":[153,197,201],"effect":[155,252],"at":[156],"time.":[158],"Moreover,":[159,312],"reduces":[163],"computing":[164],"time":[165],"memory":[167],"requirements.The":[168],"following":[169],"steps":[170],"locate":[174],"genome":[175,313,334],"segments":[176,317],"displaying":[177],"strong":[178],"highest":[184],"-":[185],"log(p-value)":[186],"in":[187,229,253,297,303,308,321],"chromosome":[189,255,277],"is":[190,195,210,220,245],"selected,":[191],"segment":[194,227,275],"expanded":[196],"Mb":[198,202],"upstream":[199],"downstream":[203],"marker.":[206],"A":[207],"information":[214],"markers":[217],"only,":[218],"as":[222,327],"variance-covariance":[224],"also":[233],"includes":[234],"random":[238],"likelihood":[243],"ratio":[244],"then":[246],"every":[254],"against":[256],"reduced":[258],"In":[267],"case":[269],"study":[270],"pigs,":[272],"significant":[274],"6":[278],"explained":[279],"11%":[280],"total":[282],"genetic":[283],"CONCLUSIONS:":[285],"their":[293],"own":[294],"helps":[296],"detecting":[298],"specific":[299,333],"regions":[301,335],"involved":[302],"variance,":[306],"reducing":[309],"false":[310],"positives.":[311],"scanning":[314],"candidate":[316],"can":[318],"be":[319],"meta-analyses":[322],"genome-wide":[324],"studies,":[326],"it":[328],"enables":[329],"detection":[331],"affect":[337],"an":[338],"economically":[339],"relevant":[340],"trait":[341],"multiple":[344],"populations.":[345]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1}],"updated_date":"2026-05-14T08:36:36.166977","created_date":"2016-06-24T00:00:00"}