{"id":"https://openalex.org/W2020098650","doi":"https://doi.org/10.1186/1471-2105-13-s12-a4","title":"RNASeq profiling of UTR expression during neuronal plasticity","display_name":"RNASeq profiling of UTR expression during neuronal plasticity","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W2020098650","doi":"https://doi.org/10.1186/1471-2105-13-s12-a4","mag":"2020098650"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-13-s12-a4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-13-S12-A4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-13-S12-A4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060935645","display_name":"Benjamin J. Harrison","orcid":"https://orcid.org/0000-0002-6078-5060"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Benjamin J Harrison","raw_affiliation_strings":["Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA","Kentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, KY, 40292, USA"],"affiliations":[{"raw_affiliation_string":"Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]},{"raw_affiliation_string":"Kentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062202807","display_name":"Robert M Flight","orcid":"https://orcid.org/0000-0001-8141-7788"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M Flight","raw_affiliation_strings":["Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA"],"affiliations":[{"raw_affiliation_string":"Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049771425","display_name":"Abdallah M. Eteleeb","orcid":"https://orcid.org/0000-0001-9045-250X"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abdallah Eteleeb","raw_affiliation_strings":["Department of Computer Engineering and Computer Science, University of Louisville, Louisville, KY, 40292, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering and Computer Science, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034707578","display_name":"Eric C. Rouchka","orcid":"https://orcid.org/0000-0003-3487-6572"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric C Rouchka","raw_affiliation_strings":["Department of Computer Engineering and Computer Science, University of Louisville, Louisville, KY, 40292, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering and Computer Science, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038602012","display_name":"Jeffrey C. Petruska","orcid":"https://orcid.org/0000-0002-3068-2677"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey C Petruska","raw_affiliation_strings":["Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA","Kentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, KY, 40292, USA"],"affiliations":[{"raw_affiliation_string":"Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]},{"raw_affiliation_string":"Kentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5060935645"],"corresponding_institution_ids":["https://openalex.org/I142740786"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.2689,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.57520089,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"13","issue":"S12","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dorsal-root-ganglion","display_name":"Dorsal root ganglion","score":0.7350971102714539},{"id":"https://openalex.org/keywords/spinal-cord","display_name":"Spinal cord","score":0.6843437552452087},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6789230704307556},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.600287914276123},{"id":"https://openalex.org/keywords/untranslated-region","display_name":"Untranslated region","score":0.5759413838386536},{"id":"https://openalex.org/keywords/three-prime-untranslated-region","display_name":"Three prime untranslated region","score":0.4698442816734314},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.46736881136894226},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.43830782175064087},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.41943615674972534},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3190488815307617},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16275277733802795}],"concepts":[{"id":"https://openalex.org/C2776281502","wikidata":"https://www.wikidata.org/wiki/Q1395415","display_name":"Dorsal root ganglion","level":3,"score":0.7350971102714539},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.6843437552452087},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6789230704307556},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.600287914276123},{"id":"https://openalex.org/C89604277","wikidata":"https://www.wikidata.org/wiki/Q424345","display_name":"Untranslated region","level":4,"score":0.5759413838386536},{"id":"https://openalex.org/C22667442","wikidata":"https://www.wikidata.org/wiki/Q3272830","display_name":"Three prime untranslated region","level":5,"score":0.4698442816734314},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.46736881136894226},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.43830782175064087},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41943615674972534},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3190488815307617},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16275277733802795}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/1471-2105-13-s12-a4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-13-S12-A4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2418928","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3409041","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-13-s12-a4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a4","pdf_url":"https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-13-S12-A4","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G230544147","display_name":null,"funder_award_id":"3P20RR016481-09S1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4265003428","display_name":null,"funder_award_id":"P20 GM103436","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5143913891","display_name":null,"funder_award_id":"RR0164","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6083127429","display_name":null,"funder_award_id":"00001","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G7446328255","display_name":null,"funder_award_id":"GM103436","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8198795195","display_name":null,"funder_award_id":"00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320309490","display_name":"Paralyzed Veterans of America","ror":"https://ror.org/00pfg3v73"},{"id":"https://openalex.org/F4320313699","display_name":"Kentucky Spinal Cord and Head Injury Research Trust","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2020098650.pdf","grobid_xml":"https://content.openalex.org/works/W2020098650.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W1524308920"],"related_works":["https://openalex.org/W2386767893","https://openalex.org/W2130669936","https://openalex.org/W3145919624","https://openalex.org/W4230503687","https://openalex.org/W977309228","https://openalex.org/W2063674507","https://openalex.org/W2037244830","https://openalex.org/W2073834597","https://openalex.org/W2052632013","https://openalex.org/W2564222003"],"abstract_inverted_index":{"Background":[0],"Neurons":[1],"interact":[2,89],"with,":[3],"and":[4,35,44,88,112],"are":[5,10,22,28,126],"influenced":[6],"by,":[7],"tissues":[8],"that":[9,99,120,147,157,167],"remote":[11,77],"from":[12,49,73],"the":[13,32,63,102],"cell":[14,20],"body.":[15],"For":[16,131],"example,":[17,132],"sensory":[18],"neuron":[19],"bodies":[21],"located":[23],"within":[24],"peri-spinal":[25],"ganglia":[26],"but":[27],"connected":[29],"to":[30,71,85,98,106,171],"both":[31],"spinal":[33],"cord":[34,53],"skin":[36],"via":[37],"their":[38,91],"axons":[39],"projecting":[40],"through":[41],"dorsal":[42],"roots":[43],"peripheral":[45],"nerves.":[46],"Biochemical":[47],"signals":[48,72,87],"anatomical":[50],"compartments":[51],"(spinal":[52],"/":[54,56,58,60],"root":[55],"ganglion":[57],"nerve":[59],"skin)":[61],"modulate":[62],"molecular":[64],"biology":[65],"of":[66,75,117,124,151,178],"neurons":[67,83],"which":[68,82],"can":[69],"respond":[70,84],"any/all":[74],"these":[76,86],"regions.":[78],"One":[79],"mechanism":[80],"by":[81,94],"with":[90],"targets":[92],"is":[93,104,168],"actively":[95],"transporting":[96],"mRNA":[97,103,152],"region.":[100],"There,":[101],"translated":[105],"produce":[107],"protein":[108],"at":[109],"locally-determined":[110],"positions":[111],"times.":[113],"A":[114],"growing":[115],"body":[116],"evidence":[118],"shows":[119],"untranslated":[121],"regions":[122],"(UTRs)":[123],"genes":[125],"important":[127],"for":[128,141],"this":[129],"targeting.":[130],"3\u2019-UTRs":[133],"contain":[134],"50nt":[135],"\u201czip":[136],"code\u201d":[137],"consensus":[138],"binding":[139],"sites":[140],"cis-acting":[142],"zip":[143],"code-binding":[144],"proteins":[145],"(ZPBs)":[146],"drive":[148],"axonal":[149,164],"targeting":[150],"[1].":[153],"We":[154],"therefore":[155],"hypothesized":[156],"gene":[158],"expression":[159],"during":[160],"collateral":[161],"sprouting,":[162],"an":[163],"growth":[165],"process":[166],"highly":[169],"responsive":[170],"target-derived":[172],"factors,":[173],"might":[174],"involve":[175],"differential":[176],"regulation":[177],"UTR":[179],"components.":[180]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}