{"id":"https://openalex.org/W2057417580","doi":"https://doi.org/10.1186/1471-2105-13-s12-a21","title":"Experimental and computational analysis of mouse sleep-wake dynamics","display_name":"Experimental and computational analysis of mouse sleep-wake dynamics","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W2057417580","doi":"https://doi.org/10.1186/1471-2105-13-s12-a21","mag":"2057417580"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-13-s12-a21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a21","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-S12-A21","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-S12-A21","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091431299","display_name":"Farid Yaghouby","orcid":"https://orcid.org/0000-0002-5380-2483"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Farid Yaghouby","raw_affiliation_strings":["Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","Center for Biomedical Engineering, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100458330","display_name":"Ting Zhang","orcid":"https://orcid.org/0000-0002-8067-9994"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ting Zhang","raw_affiliation_strings":["Department of Biology, University of Kentucky, Lexington, KY, 40506, USA","Department of Biology, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Biology, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006096021","display_name":"Martin Striz","orcid":null},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Striz","raw_affiliation_strings":["Department of Biology, University of Kentucky, Lexington, KY, 40506, USA","Department of Biology, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Department of Biology, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108292275","display_name":"James Crawford","orcid":null},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Crawford","raw_affiliation_strings":["Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","Center for Biomedical Engineering, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014574021","display_name":"Kevin D. Donohue","orcid":"https://orcid.org/0000-0003-4423-6296"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin Donohue","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Kentucky, Lexington, KY, 40506, USA","[Department of Electrical and Computer Engineering, University of Kentucky, Lexington, USA]"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"[Department of Electrical and Computer Engineering, University of Kentucky, Lexington, USA]","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103175652","display_name":"Bruce F. O\u2019Hara","orcid":"https://orcid.org/0000-0003-1418-101X"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce O\u2019Hara","raw_affiliation_strings":["Department of Biology, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041765061","display_name":"Sridhar Sunderam","orcid":"https://orcid.org/0000-0002-2457-6157"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sridhar Sunderam","raw_affiliation_strings":["Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","Center for Biomedical Engineering, University of Kentucky, Lexington, USA"],"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, KY, 40506, USA","institution_ids":["https://openalex.org/I143302722"]},{"raw_affiliation_string":"Center for Biomedical Engineering, University of Kentucky, Lexington, USA","institution_ids":["https://openalex.org/I143302722"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5091431299"],"corresponding_institution_ids":["https://openalex.org/I143302722"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12773224,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"S12","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9670000076293945,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wake","display_name":"Wake","score":0.7072214484214783},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.545270562171936},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42033863067626953},{"id":"https://openalex.org/keywords/sleep","display_name":"Sleep (system call)","score":0.4112928509712219},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.40917399525642395},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.36811327934265137},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.33447057008743286},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.15408453345298767},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.11686661839485168},{"id":"https://openalex.org/keywords/aerospace-engineering","display_name":"Aerospace engineering","score":0.10897848010063171},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.1071380078792572},{"id":"https://openalex.org/keywords/acoustics","display_name":"Acoustics","score":0.07985588908195496}],"concepts":[{"id":"https://openalex.org/C48939323","wikidata":"https://www.wikidata.org/wiki/Q294879","display_name":"Wake","level":2,"score":0.7072214484214783},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.545270562171936},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42033863067626953},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.4112928509712219},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40917399525642395},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36811327934265137},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.33447057008743286},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.15408453345298767},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11686661839485168},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.10897848010063171},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.1071380078792572},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.07985588908195496}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/1471-2105-13-s12-a21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a21","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-S12-A21","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2418941","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3409060","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-13-s12-a21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-s12-a21","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-S12-A21","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7099999785423279,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2057417580.pdf","grobid_xml":"https://content.openalex.org/works/W2057417580.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2757285599","https://openalex.org/W2376025146","https://openalex.org/W161151693","https://openalex.org/W3195741387","https://openalex.org/W2314669870","https://openalex.org/W2883444180","https://openalex.org/W4381570180","https://openalex.org/W2955635855","https://openalex.org/W4324257240","https://openalex.org/W2379898265"],"abstract_inverted_index":{"Materials":[0],"and":[1],"methods":[2],"In":[3],"this":[4,48],"study":[5],"we":[6,56,96],"explore":[7],"the":[8,16,23,37,76],"utility":[9],"of":[10],"a":[11,19,58],"noninvasive":[12],"method":[13],"based":[14],"on":[15,22],"signal":[17,39],"from":[18,44],"piezoelectric":[20],"sensor":[21,78],"cage":[24],"floor":[25],"for":[26],"scoring":[27],"sleep-wake":[28],"behavior":[29],"in":[30,90],"mice.":[31],"It":[32],"was":[33,49],"previously":[34],"demonstrated":[35],"that":[36,100],"piezo":[38,64,77,98],"can":[40],"accurately":[41],"discriminate":[42],"sleep":[43,92,110],"wake":[45],"activity;":[46],"however,":[47],"verified":[50],"mostly":[51],"by":[52,62],"visual":[53],"observation.":[54],"Here":[55],"perform":[57],"more":[59],"objective":[60],"validation":[61],"correlating":[63],"measurements":[65],"with":[66],"EMG":[67],"activity,":[68],"which":[69],"is":[70,79,87],"dramatically":[71],"suppressed":[72],"during":[73],"sleep.":[74],"Furthermore,":[75],"sensitive":[80],"to":[81,94,104,106],"respiration-related":[82],"thoracic":[83],"movements.":[84],"Since":[85],"breathing":[86,102],"relatively":[88],"irregular":[89],"REM":[91],"compared":[93],"non-REM,":[95],"extract":[97],"features":[99],"reflect":[101],"regularity":[103],"try":[105],"distinguish":[107],"between":[108],"these":[109],"states.":[111]},"counts_by_year":[],"updated_date":"2026-03-17T09:09:15.849793","created_date":"2025-10-10T00:00:00"}