{"id":"https://openalex.org/W2046468203","doi":"https://doi.org/10.1186/1471-2105-13-273","title":"Exploiting protein flexibility to predict the location of allosteric sites","display_name":"Exploiting protein flexibility to predict the location of allosteric sites","publication_year":2012,"publication_date":"2012-10-25","ids":{"openalex":"https://openalex.org/W2046468203","doi":"https://doi.org/10.1186/1471-2105-13-273","mag":"2046468203","pmid":"https://pubmed.ncbi.nlm.nih.gov/23095452"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-13-273","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-273","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-273","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-273","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050880477","display_name":"Alejandro Panjkovich","orcid":"https://orcid.org/0000-0002-9111-3232"},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Alejandro Panjkovich","raw_affiliation_strings":["Institute of Biotechnology and Biomedicine, Universitat Aut\u00f2noma de Barcelona, 08193 Cerdanyola del Vall\u00e8s, Spain","Institute of Biotechnology and Biomedicine (IBB), Universitat Aut\u00f2noma de Barcelona (UAB), Cerdanyola del Vall\u00e8s, Spain"],"affiliations":[{"raw_affiliation_string":"Institute of Biotechnology and Biomedicine, Universitat Aut\u00f2noma de Barcelona, 08193 Cerdanyola del Vall\u00e8s, Spain","institution_ids":["https://openalex.org/I123044942"]},{"raw_affiliation_string":"Institute of Biotechnology and Biomedicine (IBB), Universitat Aut\u00f2noma de Barcelona (UAB), Cerdanyola del Vall\u00e8s, Spain","institution_ids":["https://openalex.org/I123044942"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027747641","display_name":"Xavier Daura","orcid":"https://orcid.org/0000-0001-9235-6730"},"institutions":[{"id":"https://openalex.org/I11932220","display_name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats","ror":"https://ror.org/0371hy230","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I11932220"]},{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Xavier Daura","raw_affiliation_strings":["Catalan Institution for Research and Advanced Studies (ICREA), 08010, Barcelona, Spain","Institute of Biotechnology and Biomedicine (IBB), Universitat Aut\u00f2noma de Barcelona (UAB), 08193, Cerdanyola del Vall\u00e8s, Spain","Institute of Biotechnology and Biomedicine (IBB)Universitat Aut\u00f2noma de Barcelona (UAB), Cerdanyola del Vall\u00e8s, Spain","Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Catalan Institution for Research and Advanced Studies (ICREA), 08010, Barcelona, Spain","institution_ids":["https://openalex.org/I11932220"]},{"raw_affiliation_string":"Institute of Biotechnology and Biomedicine (IBB), Universitat Aut\u00f2noma de Barcelona (UAB), 08193, Cerdanyola del Vall\u00e8s, Spain","institution_ids":["https://openalex.org/I123044942"]},{"raw_affiliation_string":"Institute of Biotechnology and Biomedicine (IBB)Universitat Aut\u00f2noma de Barcelona (UAB), Cerdanyola del Vall\u00e8s, Spain","institution_ids":["https://openalex.org/I123044942"]},{"raw_affiliation_string":"Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain","institution_ids":["https://openalex.org/I11932220"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050880477"],"corresponding_institution_ids":["https://openalex.org/I123044942"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":5.8742,"has_fulltext":true,"cited_by_count":87,"citation_normalized_percentile":{"value":0.96544128,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"13","issue":"1","first_page":"273","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allosteric-regulation","display_name":"Allosteric regulation","score":0.9817123413085938},{"id":"https://openalex.org/keywords/allosteric-enzyme","display_name":"Allosteric enzyme","score":0.6519469618797302},{"id":"https://openalex.org/keywords/flexibility","display_name":"Flexibility (engineering)","score":0.603786051273346},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.577191174030304},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.5564165115356445},{"id":"https://openalex.org/keywords/protein-dynamics","display_name":"Protein dynamics","score":0.5462557673454285},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.4840683043003082},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.424001544713974},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3378208875656128},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32915014028549194},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2911851704120636},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.18230438232421875},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.08531063795089722},{"id":"https://openalex.org/keywords/economics","display_name":"Economics","score":0.06766453385353088}],"concepts":[{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.9817123413085938},{"id":"https://openalex.org/C109964505","wikidata":"https://www.wikidata.org/wiki/Q3321436","display_name":"Allosteric enzyme","level":4,"score":0.6519469618797302},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.603786051273346},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.577191174030304},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5564165115356445},{"id":"https://openalex.org/C2775981520","wikidata":"https://www.wikidata.org/wiki/Q17156992","display_name":"Protein dynamics","level":3,"score":0.5462557673454285},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4840683043003082},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.424001544713974},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3378208875656128},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32915014028549194},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2911851704120636},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18230438232421875},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08531063795089722},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.06766453385353088},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018583","descriptor_name":"Pliability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018583","descriptor_name":"Pliability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018583","descriptor_name":"Pliability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1186/1471-2105-13-273","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-273","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-273","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:23095452","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23095452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:ddd.uab.cat:112722","is_oa":true,"landing_page_url":"http://ddd.uab.cat/record/112722","pdf_url":null,"source":{"id":"https://openalex.org/S4306400381","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ddd.uab.cat:112401","is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/112401","pdf_url":"https://ddd.uab.cat/record/112401","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:13fcb61ac1df4fafbaf13f2972300f34","is_oa":true,"landing_page_url":"https://doaj.org/article/13fcb61ac1df4fafbaf13f2972300f34","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 13, Iss 1, p 273 (2012)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2565237","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3562710","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3562710","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3562710","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-13-273","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-273","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-273","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G131381412","display_name":"Identification and validation of novel drug targets in Gram-negative bacteria by global search: a trans-system approach","funder_award_id":"223101","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G1346408566","display_name":null,"funder_award_id":"HEALTH","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":"https://ror.org/034900433"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2046468203.pdf","grobid_xml":"https://content.openalex.org/works/W2046468203.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1896710611","https://openalex.org/W1964640688","https://openalex.org/W1965076207","https://openalex.org/W1967095911","https://openalex.org/W1973951655","https://openalex.org/W1974645077","https://openalex.org/W1975459052","https://openalex.org/W1988462018","https://openalex.org/W1990769556","https://openalex.org/W1991383888","https://openalex.org/W2002295098","https://openalex.org/W2003955253","https://openalex.org/W2004175162","https://openalex.org/W2005474992","https://openalex.org/W2008701121","https://openalex.org/W2009313526","https://openalex.org/W2012749168","https://openalex.org/W2015861303","https://openalex.org/W2016386715","https://openalex.org/W2018535049","https://openalex.org/W2024828265","https://openalex.org/W2026724593","https://openalex.org/W2037298322","https://openalex.org/W2043835419","https://openalex.org/W2044363505","https://openalex.org/W2048934130","https://openalex.org/W2049661341","https://openalex.org/W2049682677","https://openalex.org/W2052883399","https://openalex.org/W2055823413","https://openalex.org/W2061463182","https://openalex.org/W2061875631","https://openalex.org/W2062568746","https://openalex.org/W2067416774","https://openalex.org/W2069777230","https://openalex.org/W2074129172","https://openalex.org/W2074929227","https://openalex.org/W2078176948","https://openalex.org/W2078409242","https://openalex.org/W2079048722","https://openalex.org/W2081201773","https://openalex.org/W2083496215","https://openalex.org/W2083975423","https://openalex.org/W2092001191","https://openalex.org/W2095420958","https://openalex.org/W2102449622","https://openalex.org/W2111729275","https://openalex.org/W2112109058","https://openalex.org/W2115928493","https://openalex.org/W2116251480","https://openalex.org/W2121293808","https://openalex.org/W2134528197","https://openalex.org/W2140889378","https://openalex.org/W2145429771","https://openalex.org/W2147284000","https://openalex.org/W2157605186","https://openalex.org/W2158714788","https://openalex.org/W2159327390","https://openalex.org/W2159990074","https://openalex.org/W2164306929","https://openalex.org/W2168002683","https://openalex.org/W2408796255","https://openalex.org/W2885134480","https://openalex.org/W4231526978"],"related_works":["https://openalex.org/W2049682677","https://openalex.org/W2463850709","https://openalex.org/W2034301964","https://openalex.org/W2052504582","https://openalex.org/W4220959342","https://openalex.org/W2474016806","https://openalex.org/W4366407519","https://openalex.org/W2361360078","https://openalex.org/W2051337563","https://openalex.org/W2912530158"],"abstract_inverted_index":{"We":[0],"introduce":[1],"a":[2,16,32,44],"simple":[3],"computational":[4],"approach":[5],"to":[6],"predict":[7],"the":[8,20,29,67],"presence":[9],"and":[10],"position":[11],"of":[12,22,31,49],"allosteric":[13,54],"sites":[14],"in":[15,24,59],"protein":[17,25],"based":[18],"on":[19],"analysis":[21],"changes":[23],"normal":[26],"modes":[27],"upon":[28,64],"binding":[30],"coarse-grained":[33],"ligand":[34],"at":[35],"predicted":[36],"cavities.":[37],"Its":[38],"performance":[39],"has":[40],"been":[41],"demonstrated":[42],"using":[43],"newly":[45],"curated":[46],"non-redundant":[47],"set":[48],"91":[50],"proteins":[51],"with":[52],"reported":[53],"properties.":[55],"The":[56],"software":[57],"developed":[58],"this":[60],"work":[61],"is":[62],"available":[63],"request":[65],"from":[66],"authors.":[68]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}