{"id":"https://openalex.org/W2155400598","doi":"https://doi.org/10.1186/1471-2105-13-236","title":"Correlation analysis of the side-chains conformational distribution in bound and unbound proteins","display_name":"Correlation analysis of the side-chains conformational distribution in bound and unbound proteins","publication_year":2012,"publication_date":"2012-09-17","ids":{"openalex":"https://openalex.org/W2155400598","doi":"https://doi.org/10.1186/1471-2105-13-236","mag":"2155400598","pmid":"https://pubmed.ncbi.nlm.nih.gov/22984947"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-13-236","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-236","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-236","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-236","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063140366","display_name":"Tatsiana Kirys","orcid":null},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]},{"id":"https://openalex.org/I4210105192","display_name":"United Institute of Informatics Problems","ror":"https://ror.org/01ccbsb07","country_code":"BY","type":"facility","lineage":["https://openalex.org/I151823869","https://openalex.org/I4210105192","https://openalex.org/I4210116091"]}],"countries":["BY","US"],"is_corresponding":false,"raw_author_name":"Tatsiana Kirys","raw_affiliation_strings":["Center for Bioinformatics, The University of Kansas, Lawrence, KS 66047, USA","United Institute of Informatics Problems, National Academy of Sciences, Minsk, Belarus","Center for Bioinformatics, The University of Kansas, Lawrence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, Lawrence, KS 66047, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"United Institute of Informatics Problems, National Academy of Sciences, Minsk, Belarus","institution_ids":["https://openalex.org/I4210105192"]},{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, Lawrence, USA","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088584178","display_name":"Anatoly M. Ruvinsky","orcid":"https://orcid.org/0000-0002-8979-7559"},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anatoly M Ruvinsky","raw_affiliation_strings":["Center for Bioinformatics, The University of Kansas, 66047, Lawrence, KS, USA","Center for Bioinformatics, The University of Kansas, Lawrence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, 66047, Lawrence, KS, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, Lawrence, USA","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004434095","display_name":"Alexander V. Tuzikov","orcid":"https://orcid.org/0000-0001-5970-4852"},"institutions":[{"id":"https://openalex.org/I151823869","display_name":"National Academy of Sciences of Belarus","ror":"https://ror.org/02j8pe645","country_code":"BY","type":"government","lineage":["https://openalex.org/I151823869"]},{"id":"https://openalex.org/I4210105192","display_name":"United Institute of Informatics Problems","ror":"https://ror.org/01ccbsb07","country_code":"BY","type":"facility","lineage":["https://openalex.org/I151823869","https://openalex.org/I4210105192","https://openalex.org/I4210116091"]}],"countries":["BY"],"is_corresponding":false,"raw_author_name":"Alexander V Tuzikov","raw_affiliation_strings":["United Institute of Informatics Problems, National Academy of Sciences, 220012, Minsk, Belarus","United Institute of Informatics Problems, National Academy of Sciences, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"United Institute of Informatics Problems, National Academy of Sciences, 220012, Minsk, Belarus","institution_ids":["https://openalex.org/I151823869"]},{"raw_affiliation_string":"United Institute of Informatics Problems, National Academy of Sciences, Minsk, Belarus","institution_ids":["https://openalex.org/I4210105192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013394507","display_name":"Ilya A. Vakser","orcid":"https://orcid.org/0000-0002-5743-2934"},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ilya A Vakser","raw_affiliation_strings":["Center for Bioinformatics, The University of Kansas, 66047, Lawrence, KS, USA","Department of Molecular Biosciences, The University of Kansas, Lawrence, 66045, KS, USA","Department of Molecular Biosciences, The University of Kansas, Lawrence, USA","Center for Bioinformatics, The University of Kansas, Lawrence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, 66047, Lawrence, KS, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Department of Molecular Biosciences, The University of Kansas, Lawrence, 66045, KS, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Department of Molecular Biosciences, The University of Kansas, Lawrence, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Center for Bioinformatics, The University of Kansas, Lawrence, USA","institution_ids":["https://openalex.org/I146416000"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013394507"],"corresponding_institution_ids":["https://openalex.org/I146416000"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.403,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.63303217,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"13","issue":"1","first_page":"236","last_page":"236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.6097000241279602,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.6097000241279602,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10798","display_name":"Crystallography and molecular interactions","score":0.05790000036358833,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.03909999877214432,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/side-chain","display_name":"Side chain","score":0.5774174332618713},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4970243275165558},{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.46807608008384705},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.44159939885139465},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4136841893196106},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.328321635723114},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2846977710723877},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2298058569431305},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.20086932182312012},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10549727082252502},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.08064749836921692},{"id":"https://openalex.org/keywords/polymer","display_name":"Polymer","score":0.07439517974853516}],"concepts":[{"id":"https://openalex.org/C204921945","wikidata":"https://www.wikidata.org/wiki/Q899689","display_name":"Side chain","level":3,"score":0.5774174332618713},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4970243275165558},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.46807608008384705},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44159939885139465},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4136841893196106},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.328321635723114},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2846977710723877},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2298058569431305},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.20086932182312012},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10549727082252502},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.08064749836921692},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.07439517974853516},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-13-236","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-236","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-236","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22984947","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22984947","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:f62681bec53646f1b784f2ada31887f1","is_oa":false,"landing_page_url":"https://doaj.org/article/f62681bec53646f1b784f2ada31887f1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 13, Iss 1, p 236 (2012)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2472611","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3479416","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:kuscholarworks.ku.edu:1808/12840","is_oa":true,"landing_page_url":"http://hdl.handle.net/1808/12840","pdf_url":null,"source":{"id":"https://openalex.org/S4306400421","display_name":"KU ScholarWorks (The University of Kansas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I146416000","host_organization_name":"University of Kansas","host_organization_lineage":["https://openalex.org/I146416000"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-13-236","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-13-236","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-13-236","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production"}],"awards":[{"id":"https://openalex.org/G9237260","display_name":null,"funder_award_id":"R01GM074255","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2155400598.pdf","grobid_xml":"https://content.openalex.org/works/W2155400598.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1498124562","https://openalex.org/W1574312817","https://openalex.org/W1973657947","https://openalex.org/W1975760681","https://openalex.org/W1992426410","https://openalex.org/W1992739911","https://openalex.org/W1999727368","https://openalex.org/W2011658408","https://openalex.org/W2027189612","https://openalex.org/W2039388179","https://openalex.org/W2049659492","https://openalex.org/W2054265254","https://openalex.org/W2060339536","https://openalex.org/W2063445478","https://openalex.org/W2072917100","https://openalex.org/W2081639575","https://openalex.org/W2082006283","https://openalex.org/W2089555384","https://openalex.org/W2090683446","https://openalex.org/W2105987887","https://openalex.org/W2106383417","https://openalex.org/W2112194058","https://openalex.org/W2113415397","https://openalex.org/W2113952909","https://openalex.org/W2142796125","https://openalex.org/W2146279689","https://openalex.org/W2148970764","https://openalex.org/W2150155770","https://openalex.org/W2151323530","https://openalex.org/W2153561236","https://openalex.org/W2164130591","https://openalex.org/W2797028157","https://openalex.org/W3020957661","https://openalex.org/W3176183162","https://openalex.org/W4236706032"],"related_works":["https://openalex.org/W2013326634","https://openalex.org/W2003932717","https://openalex.org/W2914661072","https://openalex.org/W3158858967","https://openalex.org/W2897673755","https://openalex.org/W2045669197","https://openalex.org/W4200502312","https://openalex.org/W2038123933","https://openalex.org/W2044732629","https://openalex.org/W1968644367"],"abstract_inverted_index":{"BACKGROUND:":[0],"Protein":[1],"interactions":[2,16,45,240,301,334],"play":[3],"a":[4,212],"key":[5],"role":[6],"in":[7,90,219,271],"life":[8],"processes.":[9],"Characterization":[10],"of":[11,14,23,30,34,51,54,63,68,80,159,193,263,289,332,337],"conformational":[12,278],"properties":[13],"protein-protein":[15,37,239],"is":[17,59,327],"important":[18,328],"for":[19,41,61,148,250,254,329],"understanding":[20,331],"the":[21,52,55,81,85,98,103,115,127,132,139,144,157,162,183,190,194,198,205,216,246,264,272,283,287,290,293,303,306,322],"mechanisms":[22],"protein":[24,44,64,333],"association.":[25],"The":[26,49,66,135,153,202,225,268,325],"rapidly":[27],"increasing":[28],"amount":[29],"experimentally":[31],"determined":[32],"structures":[33],"proteins":[35],"and":[36,46,74,87,92,119,122,131,178,187,207,222,227,232,252,335],"complexes":[38],"provides":[39],"foundation":[40],"research":[42],"on":[43,126,215],"complex":[47],"formation.":[48],"knowledge":[50],"conformations":[53],"surface":[56,124],"side":[57,82,313],"chains":[58,83,314],"essential":[60],"modeling":[62],"complexes.":[65],"purpose":[67],"this":[69],"study":[70],"was":[71,106],"to":[72],"analyze":[73],"compare":[75],"dihedral":[76,99,173],"angle":[77,100],"distribution":[78,101,140,163,209,234],"functions":[79,141,164,210],"at":[84,245,282,286],"interface":[86,121,206,226,284,304],"non-interface":[88,123,208,228,255],"areas":[89],"bound":[91,118,221,231],"unbound":[93,120,223,233],"proteins.":[94],"RESULTS:":[95],"To":[96],"calculate":[97],"functions,":[102,235],"configuration":[104],"space":[105],"divided":[107],"into":[108],"grid":[109,133,145,199,217,248,274],"cells.":[110],"Statistical":[111],"analysis":[112,326],"showed":[113],"that":[114,318],"similarity":[116],"between":[117,138,161,204,230,297],"depends":[125],"amino":[128,150],"acid":[129,151],"type":[130],"resolution.":[134],"correlation":[136,195],"coefficients":[137],"increased":[142],"with":[143,169,197,259,311],"spacing":[146,200,249,275],"increase":[147],"all":[149],"types.":[152],"Manhattan":[154,180],"distance":[155],"showing":[156],"degree":[158],"dissimilarity":[160],"decreased":[165],"accordingly.":[166],"Short":[167],"residues":[168],"one":[170],"or":[171,241,305],"two":[172],"angles":[174],"had":[175,189,211],"higher":[176],"correlations":[177,203],"smaller":[179],"distances":[181],"than":[182,285],"longer":[184],"residues.":[185],"Met":[186],"Arg":[188],"slowest":[191],"growth":[192],"coefficient":[196],"increase.":[201],"similar":[213],"dependence":[214],"resolution":[218],"both":[220],"states.":[224],"differences":[229],"caused":[236],"by":[237,300],"biological":[238],"crystal":[242,307],"contacts,":[243],"disappeared":[244],"70\u00b0":[247],"interfaces":[251],"30\u00b0":[253],"surface,":[256],"which":[257],"agrees":[258],"an":[260],"average":[261],"span":[262],"side-chain":[265],"rotamers.":[266],"CONCLUSIONS:":[267],"two-fold":[269],"difference":[270],"critical":[273],"indicates":[276],"larger":[277],"changes":[279],"upon":[280],"binding":[281],"rest":[288],"surface.":[291],"At":[292],"same":[294],"time,":[295],"transitions":[296],"rotamers":[298],"induced":[299],"across":[302],"packing":[308],"are":[309],"rare,":[310],"most":[312],"having":[315],"local":[316],"readjustments":[317],"do":[319],"not":[320],"change":[321],"rotameric":[323],"state.":[324],"better":[330],"development":[336],"flexible":[338],"docking":[339],"approaches.":[340]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}