{"id":"https://openalex.org/W2168342464","doi":"https://doi.org/10.1186/1471-2105-12-480","title":"GC-Content Normalization for RNA-Seq Data","display_name":"GC-Content Normalization for RNA-Seq Data","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W2168342464","doi":"https://doi.org/10.1186/1471-2105-12-480","mag":"2168342464","pmid":"https://pubmed.ncbi.nlm.nih.gov/22177264"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-480","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-480","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-480","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-480","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088632823","display_name":"Davide Risso","orcid":"https://orcid.org/0000-0001-8508-5012"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]},{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Davide Risso","raw_affiliation_strings":["Division of Biostatistics and Department of Statistics, University of California, Berkeley, USA","Department of Statistical Sciences, University of Padua, Italy"],"affiliations":[{"raw_affiliation_string":"Division of Biostatistics and Department of Statistics, University of California, Berkeley, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Statistical Sciences, University of Padua, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004148440","display_name":"Katja Schwartz","orcid":"https://orcid.org/0000-0003-2031-750X"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katja Schwartz","raw_affiliation_strings":["Department of Genetics, Stanford University, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genetics, Stanford University, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058333700","display_name":"Gavin Sherlock","orcid":"https://orcid.org/0000-0002-1692-4983"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gavin Sherlock","raw_affiliation_strings":["Department of Genetics, Stanford University, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genetics, Stanford University, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018207168","display_name":"Sandrine Dudoit","orcid":"https://orcid.org/0000-0002-6069-8629"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sandrine Dudoit","raw_affiliation_strings":["Division of Biostatistics and Department of Statistics, University of California, Berkeley, USA"],"affiliations":[{"raw_affiliation_string":"Division of Biostatistics and Department of Statistics, University of California, Berkeley, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5018207168"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":13.3387,"has_fulltext":true,"cited_by_count":939,"citation_normalized_percentile":{"value":0.99340922,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"12","issue":"1","first_page":"480","last_page":"480"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/normalization","display_name":"Normalization (sociology)","score":0.8778418302536011},{"id":"https://openalex.org/keywords/rna-seq","display_name":"RNA-Seq","score":0.6885356903076172},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.6129605770111084},{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.5904151201248169},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5480901002883911},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.5297884345054626},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4611978232860565},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.44164690375328064},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.43187594413757324},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4240017831325531},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3618885278701782},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33819860219955444},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.27572160959243774},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26530662178993225},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16256704926490784}],"concepts":[{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.8778418302536011},{"id":"https://openalex.org/C107397762","wikidata":"https://www.wikidata.org/wiki/Q2542347","display_name":"RNA-Seq","level":5,"score":0.6885356903076172},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6129605770111084},{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.5904151201248169},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5480901002883911},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5297884345054626},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4611978232860565},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44164690375328064},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.43187594413757324},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4240017831325531},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3618885278701782},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33819860219955444},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.27572160959243774},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26530662178993225},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16256704926490784},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/1471-2105-12-480","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-480","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-480","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22177264","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22177264","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:biostats.bepress.com:ucbbiostat-1294","is_oa":false,"landing_page_url":"https://biostats.bepress.com/ucbbiostat/paper291","pdf_url":null,"source":{"id":"https://openalex.org/S4377196124","display_name":"Collection of Biostatistics Research Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"U.C. Berkeley Division of Biostatistics Working Paper Series","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:839a2a6afd7b4a8e9b11c6a85ec695cf","is_oa":true,"landing_page_url":"https://doaj.org/article/839a2a6afd7b4a8e9b11c6a85ec695cf","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 480 (2011)","raw_type":"article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt7937s566","is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/7937s566","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, vol 12, iss 1","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2327087","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3315510","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:www.research.unipd.it:11577/3280590","is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/3280590","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:qt7937s566","is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/7937s566","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Risso, Davide; Schwartz, Katja; Sherlock, Gavin; & Dudoit, Sandrine. (2011). GC-Content Normalization for RNA-Seq Data. BMC Bioinformatics, 12(1), 480. doi: http://dx.doi.org/10.1186/1471-2105-12-480. Retrieved from: http://www.escholarship.org/uc/item/7937s566","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-480","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-480","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-480","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321966","display_name":"Universit\u00e0 degli Studi di Padova","ror":"https://ror.org/00240q980"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2168342464.pdf","grobid_xml":"https://content.openalex.org/works/W2168342464.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1974096528","https://openalex.org/W1981509058","https://openalex.org/W1984708728","https://openalex.org/W1989849863","https://openalex.org/W1991882349","https://openalex.org/W1993907364","https://openalex.org/W1996370379","https://openalex.org/W2009458183","https://openalex.org/W2010637767","https://openalex.org/W2012016911","https://openalex.org/W2017977879","https://openalex.org/W2023621259","https://openalex.org/W2027455260","https://openalex.org/W2081098333","https://openalex.org/W2097331151","https://openalex.org/W2097337885","https://openalex.org/W2099320873","https://openalex.org/W2100668965","https://openalex.org/W2107018762","https://openalex.org/W2107060225","https://openalex.org/W2110065044","https://openalex.org/W2114104545","https://openalex.org/W2114504176","https://openalex.org/W2121211805","https://openalex.org/W2124985265","https://openalex.org/W2131088968","https://openalex.org/W2137779717","https://openalex.org/W2138773756","https://openalex.org/W2140236326","https://openalex.org/W2152239989","https://openalex.org/W2154431984","https://openalex.org/W2154537630","https://openalex.org/W2156631105","https://openalex.org/W2170219300","https://openalex.org/W2170989872"],"related_works":["https://openalex.org/W2951444558","https://openalex.org/W2914550539","https://openalex.org/W2096302356","https://openalex.org/W2768345540","https://openalex.org/W2107018762","https://openalex.org/W4241872665","https://openalex.org/W2466314544","https://openalex.org/W2069695727","https://openalex.org/W2951962472","https://openalex.org/W2191679689"],"abstract_inverted_index":{"Our":[0],"within-lane":[1],"normalization":[2],"procedures,":[3],"followed":[4],"by":[5],"between-lane":[6],"normalization,":[7],"reduce":[8],"GC-content":[9],"bias":[10],"and":[11,20],"lead":[12],"to":[13,42],"more":[14],"accurate":[15],"estimates":[16],"of":[17,22,33,46],"expression":[18],"fold-changes":[19],"tests":[21],"differential":[23],"expression.":[24],"Such":[25],"results":[26],"are":[27],"crucial":[28],"for":[29],"the":[30,43],"biological":[31],"interpretation":[32],"RNA-Seq":[34],"experiments,":[35],"where":[36],"downstream":[37],"analyses":[38],"can":[39],"be":[40],"sensitive":[41],"supplied":[44],"lists":[45],"genes.":[47]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":64},{"year":2024,"cited_by_count":107},{"year":2023,"cited_by_count":96},{"year":2022,"cited_by_count":103},{"year":2021,"cited_by_count":102},{"year":2020,"cited_by_count":83},{"year":2019,"cited_by_count":59},{"year":2018,"cited_by_count":62},{"year":2017,"cited_by_count":55},{"year":2016,"cited_by_count":61},{"year":2015,"cited_by_count":39},{"year":2014,"cited_by_count":52},{"year":2013,"cited_by_count":30},{"year":2012,"cited_by_count":18}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}