{"id":"https://openalex.org/W1995040284","doi":"https://doi.org/10.1186/1471-2105-12-431","title":"AIGO: Towards a unified framework for the Analysis and the Inter-comparison of GO functional annotations","display_name":"AIGO: Towards a unified framework for the Analysis and the Inter-comparison of GO functional annotations","publication_year":2011,"publication_date":"2011-11-03","ids":{"openalex":"https://openalex.org/W1995040284","doi":"https://doi.org/10.1186/1471-2105-12-431","mag":"1995040284","pmid":"https://pubmed.ncbi.nlm.nih.gov/22054122"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-431","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-431","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-431","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-431","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011704636","display_name":"Micha\u00ebl Defoin-Platel","orcid":"https://orcid.org/0000-0001-7227-1414"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Michael Defoin-Platel","raw_affiliation_strings":["Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK. michael.defoin-platel@rothamsted.ac.uk","Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK. michael.defoin-platel@rothamsted.ac.uk","institution_ids":["https://openalex.org/I2799553609"]},{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#","institution_ids":["https://openalex.org/I2799553609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048753735","display_name":"Matthew Hindle","orcid":"https://orcid.org/0000-0002-6870-4069"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew M Hindle","raw_affiliation_strings":["Department of Plant Science, Rothamsted Research, Harpenden, UK","Multidisciplinary Centre for Integrative Biology, The University of Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Science, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]},{"raw_affiliation_string":"Multidisciplinary Centre for Integrative Biology, The University of Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068144584","display_name":"Artem Lysenko","orcid":"https://orcid.org/0000-0002-1441-0604"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Artem Lysenko","raw_affiliation_strings":["Department of Plant Science, Rothamsted Research, Harpenden, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Science, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022106232","display_name":"Stephen J. Powers","orcid":"https://orcid.org/0000-0003-3349-4425"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen J Powers","raw_affiliation_strings":["Department of Plant Science, Rothamsted Research, Harpenden, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Science, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009510755","display_name":"D. Z. Habash","orcid":"https://orcid.org/0000-0003-2222-4825"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dimah Z Habash","raw_affiliation_strings":["Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]},{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#","institution_ids":["https://openalex.org/I2799553609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038901466","display_name":"Chris Rawlings","orcid":"https://orcid.org/0000-0003-3702-1633"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher J Rawlings","raw_affiliation_strings":["Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]},{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#","institution_ids":["https://openalex.org/I2799553609"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068307947","display_name":"Mansoor Saqi","orcid":"https://orcid.org/0000-0003-1222-475X"},"institutions":[{"id":"https://openalex.org/I2799553609","display_name":"Rothamsted Research","ror":"https://ror.org/0347fy350","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2799553609","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mansoor Saqi","raw_affiliation_strings":["Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK","institution_ids":["https://openalex.org/I2799553609"]},{"raw_affiliation_string":"Department of Biomathematics and Bioinformatics, Rothamsted Research, Harpenden, UK#TAB#","institution_ids":["https://openalex.org/I2799553609"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5011704636"],"corresponding_institution_ids":["https://openalex.org/I2799553609"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.7981,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.70502095,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"12","issue":"1","first_page":"431","last_page":"431"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9266999959945679,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9266999959945679,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.02239999920129776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.01899999938905239,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7953254580497742},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7393909692764282},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.7208739519119263},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.482791543006897},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.46652066707611084},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.46292683482170105},{"id":"https://openalex.org/keywords/precision-and-recall","display_name":"Precision and recall","score":0.4215678870677948},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.40402650833129883},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3324539065361023},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3304041028022766}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7953254580497742},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7393909692764282},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.7208739519119263},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.482791543006897},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.46652066707611084},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.46292683482170105},{"id":"https://openalex.org/C81669768","wikidata":"https://www.wikidata.org/wiki/Q2359161","display_name":"Precision and recall","level":2,"score":0.4215678870677948},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.40402650833129883},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3324539065361023},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3304041028022766},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-12-431","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-431","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-431","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22054122","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22054122","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:7be57d0e43d34aadaed17134712c47c0","is_oa":false,"landing_page_url":"https://doaj.org/article/7be57d0e43d34aadaed17134712c47c0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 431 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2244357","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3237112","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-431","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-431","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-431","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2014059278","display_name":"From data to knowledge / the ONDEX System for integrating Life Sciences data sources","funder_award_id":"BB/F006039/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G2633328597","display_name":null,"funder_award_id":"BB/F006039/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4746756820","display_name":null,"funder_award_id":"BBS/E/C/00004937","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8826528480","display_name":null,"funder_award_id":"BBS/E/C/00004938","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1995040284.pdf","grobid_xml":"https://content.openalex.org/works/W1995040284.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1597538863","https://openalex.org/W1956694423","https://openalex.org/W1970582053","https://openalex.org/W1980948656","https://openalex.org/W1987611631","https://openalex.org/W1995875735","https://openalex.org/W2001338440","https://openalex.org/W2021025020","https://openalex.org/W2045220705","https://openalex.org/W2068055268","https://openalex.org/W2097795961","https://openalex.org/W2098929214","https://openalex.org/W2114049512","https://openalex.org/W2114921810","https://openalex.org/W2117805756","https://openalex.org/W2127536416","https://openalex.org/W2128049108","https://openalex.org/W2128492946","https://openalex.org/W2146389940","https://openalex.org/W2148911704","https://openalex.org/W2153636826","https://openalex.org/W2164154943","https://openalex.org/W2166361106","https://openalex.org/W2167318540","https://openalex.org/W2171602500","https://openalex.org/W2276605232","https://openalex.org/W2531563875","https://openalex.org/W4246066782"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2218034408","https://openalex.org/W2392921965","https://openalex.org/W2358755282","https://openalex.org/W2625833328","https://openalex.org/W1533177136","https://openalex.org/W4380994516","https://openalex.org/W2405355225"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,104],"response":[2],"to":[3,15,20,33,98,112,207,218],"the":[4,69,80,83,113,156,170,182,187,190,193,222,225,242],"rapid":[5],"growth":[6],"of":[7,46,68,72,79,82,115,120,126,146,158,172,181,192,195,224,245],"available":[8,174],"genome":[9,39],"sequences,":[10],"efforts":[11],"have":[12],"been":[13,252],"made":[14],"develop":[16],"automatic":[17],"inference":[18,54,160],"methods":[19],"functionally":[21],"characterize":[22],"them.":[23],"Pipelines":[24],"that":[25,255],"infer":[26],"functional":[27,116,127,175,214,247,260],"annotation":[28,166,199],"are":[29],"now":[30],"routinely":[31],"used":[32],"produce":[34],"new":[35,256],"annotations":[36,85,215,261],"at":[37],"a":[38,43,66,109,134,234,238,266],"scale":[40],"and":[41,58,101,131,142,168,189,212,216,220],"for":[42,61,186,241],"broad":[44],"variety":[45],"species.":[47],"These":[48],"pipelines":[49],"differ":[50],"widely":[51],"in":[52,133,227,265],"their":[53,139],"algorithms,":[55],"confidence":[56],"thresholds":[57],"data":[59],"sources":[60],"reasoning.":[62],"This":[63,231,249],"heterogeneity":[64],"makes":[65],"comparison":[67],"relative":[70],"merits":[71],"each":[73],"approach":[74,111],"extremely":[75],"complex.":[76],"The":[77,144,177,201],"evaluation":[78],"quality":[81],"resultant":[84],"is":[86,91,129,149,179,233],"also":[87,204,217],"challenging":[88],"given":[89],"there":[90],"often":[92],"no":[93],"existing":[94],"gold-standard":[95],"against":[96],"which":[97,137],"evaluate":[99],"precision":[100],"recall.":[102],"RESULTS:":[103],"this":[105,147],"paper,":[106],"we":[107],"present":[108],"pragmatic":[110],"study":[114,244],"annotations.":[117,176,248],"An":[118],"ensemble":[119],"12":[121],"metrics,":[122],"describing":[123],"various":[124,228],"aspects":[125],"annotations,":[128],"defined":[130],"implemented":[132],"unified":[135,239],"framework,":[136],"facilitates":[138],"systematic":[140,243],"analysis":[141,226],"inter-comparison.":[143],"use":[145],"framework":[148,178,240,250],"demonstrated":[150],"on":[151,258],"three":[152],"illustrative":[153],"examples:":[154],"analysing":[155],"outputs":[157],"state-of-the-art":[159],"pipelines,":[161],"comparing":[162],"electronic":[163],"versus":[164],"manual":[165],"methods,":[167],"monitoring":[169],"evolution":[171],"publicly":[173],"part":[180],"AIGO":[183,202],"library":[184,203],"(http://code.google.com/p/aigo)":[185],"Analysis":[188],"Inter-comparison":[191],"products":[194],"Gene":[196],"Ontology":[197],"(GO)":[198],"pipelines.":[200],"provides":[205],"functionalities":[206],"easily":[208],"load,":[209],"analyse,":[210],"manipulate":[211],"compare":[213],"plot":[219],"export":[221],"results":[223],"formats.":[229],"CONCLUSIONS:":[230],"work":[232],"step":[235],"toward":[236],"developing":[237],"GO":[246,259],"has":[251],"designed":[253],"so":[254],"metrics":[257],"can":[262],"be":[263],"added":[264],"very":[267],"straightforward":[268],"way.":[269]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}