{"id":"https://openalex.org/W2076373433","doi":"https://doi.org/10.1186/1471-2105-12-351","title":"Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case","display_name":"Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case","publication_year":2011,"publication_date":"2011-08-22","ids":{"openalex":"https://openalex.org/W2076373433","doi":"https://doi.org/10.1186/1471-2105-12-351","mag":"2076373433","pmid":"https://pubmed.ncbi.nlm.nih.gov/21859449"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-351","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-351","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-351","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-351","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103380057","display_name":"Thomas A. Russ","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas A Russ","raw_affiliation_strings":["Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","Information Sciences Institute, University of Southern California, Marina Del Rey, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina Del Rey, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112629679","display_name":"C. R. Ramakrishnan","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cartic Ramakrishnan","raw_affiliation_strings":["Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","Information Sciences Institute, University of Southern California, Marina del Rey, USA","Information Sciences Institute, University of Southern California, Marina Del Rey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina Del Rey, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060225743","display_name":"Eduard Hovy","orcid":"https://orcid.org/0000-0002-3270-7903"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eduard H Hovy","raw_affiliation_strings":["Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","Information Sciences Institute, University of Southern California, Marina del Rey, USA","Information Sciences Institute, University of Southern California, Marina Del Rey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina Del Rey, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006605981","display_name":"Mihail Bota","orcid":"https://orcid.org/0000-0002-6499-162X"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mihail Bota","raw_affiliation_strings":["Brain Architecture Group, University of Southern California, Los Angeles, CA, USA","Brain Architecture Group, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brain Architecture Group, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Brain Architecture Group, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087346345","display_name":"Gully Burns","orcid":"https://orcid.org/0000-0003-1493-865X"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gully APC Burns","raw_affiliation_strings":["Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","Information Sciences Institute, University of Southern California, Marina del Rey, USA","Information Sciences Institute, University of Southern California, Marina Del Rey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina del Rey, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Information Sciences Institute, University of Southern California, Marina Del Rey, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":2.1897,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.87916818,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"351","last_page":"351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8410999774932861,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8410999774932861,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10778","display_name":"Philosophy and History of Science","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11010","display_name":"Logic, Reasoning, and Knowledge","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8075416088104248},{"id":"https://openalex.org/keywords/knowledge-representation-and-reasoning","display_name":"Knowledge representation and reasoning","score":0.49703505635261536},{"id":"https://openalex.org/keywords/table","display_name":"Table (database)","score":0.42159321904182434},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42051684856414795},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2988777160644531}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8075416088104248},{"id":"https://openalex.org/C161301231","wikidata":"https://www.wikidata.org/wiki/Q3478658","display_name":"Knowledge representation and reasoning","level":2,"score":0.49703505635261536},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.42159321904182434},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42051684856414795},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2988777160644531}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-12-351","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-351","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-351","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21859449","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21859449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:2f963fcff18746c2bd1fbf09af729429","is_oa":false,"landing_page_url":"https://doaj.org/article/2f963fcff18746c2bd1fbf09af729429","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 351 (2011)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3176268","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3176268","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-351","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-351","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-351","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G182816247","display_name":null,"funder_award_id":"R01 GM083871","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2032847650","display_name":null,"funder_award_id":"U24 RR025736-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3651620967","display_name":null,"funder_award_id":"U24 RR025736","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4098347278","display_name":null,"funder_award_id":"U24 GM104203","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5779719627","display_name":null,"funder_award_id":"R01 MH079068","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G5804018019","display_name":null,"funder_award_id":"R01-GM083871","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5876526592","display_name":null,"funder_award_id":"1R01MH079068-01A2","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6227581148","display_name":null,"funder_award_id":"U24 RR025736","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G7061603871","display_name":null,"funder_award_id":"1 U24 RR025736-01","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G838513495","display_name":null,"funder_award_id":"1 U24 RR025736-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2076373433.pdf","grobid_xml":"https://content.openalex.org/works/W2076373433.grobid-xml"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W57881341","https://openalex.org/W419441487","https://openalex.org/W614895547","https://openalex.org/W617643949","https://openalex.org/W1501546233","https://openalex.org/W1550232114","https://openalex.org/W1561585380","https://openalex.org/W1566743778","https://openalex.org/W1577107410","https://openalex.org/W1581613712","https://openalex.org/W1672014239","https://openalex.org/W1754668934","https://openalex.org/W1817419366","https://openalex.org/W1861830827","https://openalex.org/W1969013163","https://openalex.org/W1974385176","https://openalex.org/W1975942563","https://openalex.org/W1980009209","https://openalex.org/W1986017913","https://openalex.org/W1997097282","https://openalex.org/W1997381076","https://openalex.org/W1998017916","https://openalex.org/W1999653836","https://openalex.org/W2003302766","https://openalex.org/W2004884668","https://openalex.org/W2009577334","https://openalex.org/W2028925477","https://openalex.org/W2038665424","https://openalex.org/W2040898679","https://openalex.org/W2047968968","https://openalex.org/W2050355460","https://openalex.org/W2052042865","https://openalex.org/W2055651914","https://openalex.org/W2064440086","https://openalex.org/W2065915881","https://openalex.org/W2076327529","https://openalex.org/W2085989895","https://openalex.org/W2088199798","https://openalex.org/W2090083575","https://openalex.org/W2096525273","https://openalex.org/W2097056536","https://openalex.org/W2098580305","https://openalex.org/W2100657212","https://openalex.org/W2100871981","https://openalex.org/W2102771627","https://openalex.org/W2104990432","https://openalex.org/W2106356140","https://openalex.org/W2115570304","https://openalex.org/W2121588207","https://openalex.org/W2130430745","https://openalex.org/W2136358012","https://openalex.org/W2137653635","https://openalex.org/W2138223008","https://openalex.org/W2138996400","https://openalex.org/W2142745813","https://openalex.org/W2143543488","https://openalex.org/W2145687948","https://openalex.org/W2146693559","https://openalex.org/W2149378423","https://openalex.org/W2154282155","https://openalex.org/W2160695241","https://openalex.org/W2163670493","https://openalex.org/W2172143128","https://openalex.org/W2501077229","https://openalex.org/W2582808356","https://openalex.org/W2978847650","https://openalex.org/W2983059540","https://openalex.org/W4231041617","https://openalex.org/W4242779638","https://openalex.org/W4250297812","https://openalex.org/W4290103054","https://openalex.org/W4388247264"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655"],"abstract_inverted_index":{"BACKGROUND:":[0],"We":[1,33,223,255],"address":[2],"the":[3,30,40,58,62,75,105,127,165,174,218,226,258,266,288],"goal":[4],"of":[5,39,61,69,78,122,160,167,241,247,252,262],"curating":[6],"observations":[7,18,84],"from":[8,88],"published":[9],"experiments":[10,55],"in":[11,188],"a":[12,50,79,110,119,132,144,148,158,182,198,230,239,273,282],"generalizable":[13],"form;":[14],"reasoning":[15,209,216,244,279],"over":[16,217],"these":[17],"to":[19,28,56,73,138,143,176,181,211],"generate":[20],"interpretations":[21,166],"and":[22,96,202,233,260,277],"then":[23,256],"querying":[24],"this":[25,47,70],"interpreted":[26],"knowledge":[27,80],"supply":[29],"supporting":[31],"evidence.":[32],"present":[34],"web-application":[35],"software":[36,100],"as":[37,157,197,229,238,272],"part":[38],"'BioScholar'":[41],"project":[42],"(R01-GM083871)":[43],"that":[44,135,153],"fully":[45],"instantiates":[46],"process":[48],"for":[49,82,113,281],"well-defined":[51],"domain:":[52],"using":[53,214],"tract-tracing":[54,168],"study":[57],"neural":[59,155],"connectivity":[60,156],"rat":[63],"brain.":[64],"RESULTS:":[65],"The":[66,99],"main":[67],"contribution":[68],"work":[71],"is":[72,186,270],"provide":[74],"first":[76,224],"instantiation":[77],"representation":[81],"experimental":[83,94,124,140,178],"called":[85],"'Knowledge":[86],"Engineering":[87],"Experimental":[89],"Design'":[90],"(KEfED)":[91],"based":[92],"on":[93],"variables":[95],"their":[97],"interdependencies.":[98],"has":[101],"three":[102],"parts:":[103],"(a)":[104],"KEfED":[106,115,128,227],"model":[107],"editor":[108,112],"-":[109,131],"design":[111,259],"creating":[114],"models":[116,246,251],"by":[117],"drawing":[118],"flow":[120],"diagram":[121],"an":[123],"protocol;":[125],"(b)":[126],"data":[129,141,200],"interface":[130,152,276],"spreadsheet-like":[133],"tool":[134,171],"permits":[136],"users":[137],"enter":[139],"pertaining":[142,180],"specific":[145,183],"model;":[146],"(c)":[147],"'neural":[149],"connection":[150,162],"matrix'":[151],"presents":[154],"table":[159],"ordinal":[161],"strengths":[163],"representing":[164],"data.":[169],"This":[170,269],"also":[172],"allows":[173],"user":[175],"view":[177],"evidence":[179],"connection.":[184],"BioScholar":[185,267],"built":[187],"Flex":[189],"3.5.":[190],"It":[191],"uses":[192],"Persevere":[193],"(a":[194,204],"noSQL":[195],"database)":[196],"flexible":[199],"store":[201],"PowerLoom\u00ae":[203],"mature":[205],"First":[206],"Order":[207],"Logic":[208],"system)":[210],"execute":[212],"queries":[213],"spatial":[215],"BAMS":[219],"neuroanatomical":[220],"ontology.":[221],"CONCLUSIONS:":[222],"introduce":[225],"approach":[228,232],"general":[231],"describe":[234,257],"its":[235],"possible":[236,274],"role":[237],"way":[240],"introducing":[242],"structured":[243],"into":[245],"argumentation":[248],"within":[249],"new":[250],"scientific":[253],"publication.":[254],"implementation":[261],"our":[263],"example":[264],"application:":[265],"software.":[268],"presented":[271],"biocuration":[275],"supplementary":[278],"toolkit":[280],"larger,":[283],"more":[284],"specialized":[285],"bioinformatics":[286],"system:":[287],"Brain":[289],"Architecture":[290],"Management":[291],"System":[292],"(BAMS).":[293]},"counts_by_year":[{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":9}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}