{"id":"https://openalex.org/W2074909362","doi":"https://doi.org/10.1186/1471-2105-12-303","title":"Prototype semantic infrastructure for automated small molecule classification and annotation in lipidomics","display_name":"Prototype semantic infrastructure for automated small molecule classification and annotation in lipidomics","publication_year":2011,"publication_date":"2011-07-26","ids":{"openalex":"https://openalex.org/W2074909362","doi":"https://doi.org/10.1186/1471-2105-12-303","mag":"2074909362","pmid":"https://pubmed.ncbi.nlm.nih.gov/21791100"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-303","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-303","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-303","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-303","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004083401","display_name":"Leonid Chepelev","orcid":"https://orcid.org/0000-0001-7010-3812"},"institutions":[{"id":"https://openalex.org/I67031392","display_name":"Carleton University","ror":"https://ror.org/02qtvee93","country_code":"CA","type":"education","lineage":["https://openalex.org/I67031392"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Leonid L Chepelev","raw_affiliation_strings":["Department of Biology, Carleton University, Ottawa, Canada","Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Carleton University, Ottawa, Canada","institution_ids":["https://openalex.org/I67031392"]},{"raw_affiliation_string":"Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Canada","institution_ids":["https://openalex.org/I67031392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014954456","display_name":"Alexandre Riazanov","orcid":null},"institutions":[{"id":"https://openalex.org/I106938459","display_name":"University of New Brunswick","ror":"https://ror.org/05nkf0n29","country_code":"CA","type":"education","lineage":["https://openalex.org/I106938459"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alexandre Riazanov","raw_affiliation_strings":["Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada","institution_ids":["https://openalex.org/I106938459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040593387","display_name":"Alexandre Kouznetsov","orcid":null},"institutions":[{"id":"https://openalex.org/I106938459","display_name":"University of New Brunswick","ror":"https://ror.org/05nkf0n29","country_code":"CA","type":"education","lineage":["https://openalex.org/I106938459"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alexandre Kouznetsov","raw_affiliation_strings":["Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada","institution_ids":["https://openalex.org/I106938459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058861955","display_name":"Hong Sang Low","orcid":null},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Hong Sang Low","raw_affiliation_strings":["School of Computing, National University of Singapore, 21 Lower Kent Ridge Road, Singapore, Southeast Asia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing, National University of Singapore, 21 Lower Kent Ridge Road, Singapore, Southeast Asia","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044836472","display_name":"Michel Dumontier","orcid":"https://orcid.org/0000-0003-4727-9435"},"institutions":[{"id":"https://openalex.org/I67031392","display_name":"Carleton University","ror":"https://ror.org/02qtvee93","country_code":"CA","type":"education","lineage":["https://openalex.org/I67031392"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Michel Dumontier","raw_affiliation_strings":["Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Canada","Institute of Biochemistry, Carleton University, 1125, Colonel By Drive, Ottawa, Canada","School of Computer Science, Carleton University, 1125, Colonel By Drive, Ottawa, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Canada","institution_ids":["https://openalex.org/I67031392"]},{"raw_affiliation_string":"Institute of Biochemistry, Carleton University, 1125, Colonel By Drive, Ottawa, Canada","institution_ids":["https://openalex.org/I67031392"]},{"raw_affiliation_string":"School of Computer Science, Carleton University, 1125, Colonel By Drive, Ottawa, Canada","institution_ids":["https://openalex.org/I67031392"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080598287","display_name":"Christopher J. O. Baker","orcid":"https://orcid.org/0000-0003-4004-6479"},"institutions":[{"id":"https://openalex.org/I106938459","display_name":"University of New Brunswick","ror":"https://ror.org/05nkf0n29","country_code":"CA","type":"education","lineage":["https://openalex.org/I106938459"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Christopher JO Baker","raw_affiliation_strings":["Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Applied Statistics, University of New Brunswick, 100 Tucker Park Road, Saint John, Canada","institution_ids":["https://openalex.org/I106938459"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044836472"],"corresponding_institution_ids":["https://openalex.org/I67031392"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.9464,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.86024387,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"303","last_page":"303"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.4726000130176544,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.4726000130176544,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.10000000149011612,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.07029999792575836,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.7659660577774048},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7438254952430725},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6709368228912354},{"id":"https://openalex.org/keywords/service","display_name":"Service (business)","score":0.5512505173683167},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.5188056826591492},{"id":"https://openalex.org/keywords/semantic-web","display_name":"Semantic Web","score":0.511436402797699},{"id":"https://openalex.org/keywords/web-service","display_name":"Web service","score":0.43884649872779846},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.41966933012008667},{"id":"https://openalex.org/keywords/lipidomics","display_name":"Lipidomics","score":0.41341912746429443},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2147613763809204},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.21341192722320557},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0914340615272522}],"concepts":[{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.7659660577774048},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7438254952430725},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6709368228912354},{"id":"https://openalex.org/C2780378061","wikidata":"https://www.wikidata.org/wiki/Q25351891","display_name":"Service (business)","level":2,"score":0.5512505173683167},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.5188056826591492},{"id":"https://openalex.org/C2129575","wikidata":"https://www.wikidata.org/wiki/Q54837","display_name":"Semantic Web","level":2,"score":0.511436402797699},{"id":"https://openalex.org/C35578498","wikidata":"https://www.wikidata.org/wiki/Q193424","display_name":"Web service","level":2,"score":0.43884649872779846},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.41966933012008667},{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.41341912746429443},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2147613763809204},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.21341192722320557},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0914340615272522},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C136264566","wikidata":"https://www.wikidata.org/wiki/Q159810","display_name":"Economy","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-12-303","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-303","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-303","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21791100","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21791100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/f9cd47fe-1fb1-4c10-9648-001cbc3c74c3","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/f9cd47fe-1fb1-4c10-9648-001cbc3c74c3","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chepelev, L L, Riazanov, A, Kouznetsov, A, Low, H S, Dumontier, M & Baker, C J O 2011, 'Prototype semantic infrastructure for automated small molecule classification and annotation in lipidomics', BMC Bioinformatics, vol. 12, 303. https://doi.org/10.1186/1471-2105-12-303","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:6ee2b5c6b69041b98cfdfb70a2a03d8e","is_oa":true,"landing_page_url":"https://doaj.org/article/6ee2b5c6b69041b98cfdfb70a2a03d8e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 303 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2167015","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3163564","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-303","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-303","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-303","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.6200000047683716}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310411","display_name":"Canarie","ror":"https://ror.org/01nztpc84"},{"id":"https://openalex.org/F4320319980","display_name":"New Brunswick Innovation Foundation","ror":"https://ror.org/02rbgnh75"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2074909362.pdf","grobid_xml":"https://content.openalex.org/works/W2074909362.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W4508078","https://openalex.org/W124940209","https://openalex.org/W131196319","https://openalex.org/W174753650","https://openalex.org/W1561051808","https://openalex.org/W1972793074","https://openalex.org/W1975147762","https://openalex.org/W1975783279","https://openalex.org/W1985592898","https://openalex.org/W1996902131","https://openalex.org/W2009453329","https://openalex.org/W2010925860","https://openalex.org/W2019543926","https://openalex.org/W2033377040","https://openalex.org/W2038559836","https://openalex.org/W2040132477","https://openalex.org/W2075694192","https://openalex.org/W2081934181","https://openalex.org/W2096374069","https://openalex.org/W2099548472","https://openalex.org/W2103017472","https://openalex.org/W2133018204","https://openalex.org/W2148797284","https://openalex.org/W2160943260","https://openalex.org/W2165428180","https://openalex.org/W3009281336","https://openalex.org/W4237825176"],"related_works":["https://openalex.org/W2017497567","https://openalex.org/W2804498896","https://openalex.org/W2908070307","https://openalex.org/W2091512523","https://openalex.org/W4238045650","https://openalex.org/W2117748922","https://openalex.org/W2004558801","https://openalex.org/W2806559730","https://openalex.org/W2416426346","https://openalex.org/W4323826842"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,122,152,307],"development":[2,324],"of":[3,42,69,81,90,100,106,114,132,225,255,270,277,286,290,295,309,312,325,344,348],"high-throughput":[4,278],"experimentation":[5],"has":[6],"led":[7],"to":[8,28,62,74,247,260],"astronomical":[9],"growth":[10],"in":[11,22,39,94,142,274,329],"biologically":[12],"relevant":[13,190],"lipids":[14,240,291],"and":[15,20,31,67,98,111,136,169,188,215,241,243,265,292,341,346],"lipid":[16,124,140,174,203,219,249,296],"derivatives":[17],"identified,":[18],"screened,":[19],"deposited":[21],"numerous":[23],"online":[24],"databases.":[25],"Unfortunately,":[26],"efforts":[27],"annotate,":[29],"classify,":[30],"analyze":[32,252],"these":[33,226],"chemical":[34,56,70,96,196],"entities":[35,53,71],"have":[36,86],"largely":[37],"remained":[38],"the":[40,88,133,139,143,165,208,212,217,223,253,261,268,275,317],"hands":[41],"human":[43],"curators":[44],"using":[45,207],"manual":[46],"or":[47],"semi-automated":[48],"protocols,":[49],"leaving":[50],"many":[51],"novel":[52,327],"unclassified.":[54],"Since":[55],"function":[57],"is":[58,72,176,284],"often":[59],"closely":[60],"linked":[61],"structure,":[63],"accurate":[64,287,340],"structure-based":[65],"classification":[66,97,175,258,264,289,345],"annotation":[68,99,185,213,347],"imperative":[73],"understanding":[75],"their":[76],"functionality.":[77],"RESULTS:":[78],"As":[79],"part":[80,131],"an":[82,109,321,339],"exploratory":[83],"study,":[84],"we":[85,126],"investigated":[87],"utility":[89,224],"semantic":[91,154,334],"web":[92,116,155,305,314,335],"technologies":[93,336],"automated":[95,288],"lipids.":[101,349],"Our":[102,281],"prototype":[103,282],"framework":[104,283,319],"consists":[105],"two":[107,179],"components:":[108],"ontology":[110,125,135,161,204],"a":[112,130,183,194],"set":[113],"federated":[115,153],"services":[117,156,228,235,315],"that":[118,157,236,333],"operate":[119,158],"upon":[120,159],"it.":[121],"formal":[123],"use":[127],"here":[128],"extends":[129],"LiPrO":[134],"draws":[137],"on":[138,267],"hierarchy":[141],"LIPID":[144,262],"MAPS":[145,263],"database,":[146],"as":[147,149],"well":[148],"literature-derived":[150],"knowledge.":[151],"this":[160],"are":[162],"deployed":[163],"within":[164],"Semantic":[166],"Annotation,":[167],"Discovery,":[168],"Integration":[170],"(SADI)":[171],"framework.":[172],"Structure-based":[173],"enacted":[177],"by":[178,229],"core":[180,227],"services.":[181,306],"Firstly,":[182],"structural":[184],"service":[186,200,214],"detects":[187],"enumerates":[189],"functional":[191],"groups":[192],"for":[193,323],"specified":[195,248],"structure.":[197],"A":[198],"second":[199],"reasons":[201],"over":[202],"class":[205,297],"descriptions":[206],"attributes":[209],"obtained":[210,302],"from":[211],"identifies":[216],"appropriate":[218],"classification.":[220],"We":[221,251,331],"extend":[222],"combining":[230],"them":[231],"with":[232,299,303],"additional":[233,300],"SADI":[234,304,318],"retrieve":[237],"associations":[238],"between":[239],"proteins":[242],"identify":[244],"publications":[245],"related":[246],"types.":[250],"performance":[254],"SADI-enabled":[256],"eicosanoid":[257],"relative":[259],"reflect":[266],"contribution":[269],"our":[271],"integrative":[272],"methodology":[273],"context":[276],"lipidomics.":[279,330],"CONCLUSIONS:":[280],"capable":[285],"facile":[293],"integration":[294,311],"information":[298],"data":[301],"potential":[308],"programming-free":[310],"external":[313],"through":[316],"offers":[320],"opportunity":[322],"powerful":[326],"applications":[328],"conclude":[332],"can":[337],"provide":[338],"versatile":[342],"means":[343]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":5}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}