{"id":"https://openalex.org/W2000787234","doi":"https://doi.org/10.1186/1471-2105-12-289","title":"Bio::Homology::InterologWalk - A Perl module to build putative protein-protein interaction networks through interolog mapping","display_name":"Bio::Homology::InterologWalk - A Perl module to build putative protein-protein interaction networks through interolog mapping","publication_year":2011,"publication_date":"2011-07-18","ids":{"openalex":"https://openalex.org/W2000787234","doi":"https://doi.org/10.1186/1471-2105-12-289","mag":"2000787234","pmid":"https://pubmed.ncbi.nlm.nih.gov/21767381"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-289","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-289","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-289","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-289","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075816415","display_name":"Giuseppe Gallone","orcid":"https://orcid.org/0000-0001-6806-7226"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Giuseppe Gallone","raw_affiliation_strings":["Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK. G.Gallone@sms.ed.ac.uk","Centre for Integrative Physiology University of Edinburgh Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK. G.Gallone@sms.ed.ac.uk","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Centre for Integrative Physiology University of Edinburgh Edinburgh, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084953972","display_name":"T. Ian Simpson","orcid":"https://orcid.org/0000-0003-0495-7187"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"T Ian Simpson","raw_affiliation_strings":["Institute for Adaptive and Neural Computation, University of Edinburgh, 10 Crichton Street, Edinburgh, EH8 9AB, UK","Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Adaptive and Neural Computation, University of Edinburgh, 10 Crichton Street, Edinburgh, EH8 9AB, UK","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026384936","display_name":"J. Douglas Armstrong","orcid":"https://orcid.org/0000-0002-5397-3864"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J Douglas Armstrong","raw_affiliation_strings":["Institute for Adaptive and Neural Computation, University of Edinburgh, 10 Crichton Street, Edinburgh, EH8 9AB, UK","Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Adaptive and Neural Computation, University of Edinburgh, 10 Crichton Street, Edinburgh, EH8 9AB, UK","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020947052","display_name":"Andrew P. Jarman","orcid":"https://orcid.org/0000-0003-4036-5701"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew P Jarman","raw_affiliation_strings":["Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK","Centre for Integrative Physiology University of Edinburgh Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Centre for Integrative Physiology University of Edinburgh Edinburgh, UK","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075816415"],"corresponding_institution_ids":["https://openalex.org/I98677209"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":1.0948,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.7514065,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"12","issue":"1","first_page":"289","last_page":"289"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9376000165939331,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9376000165939331,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perl","display_name":"Perl","score":0.877906322479248},{"id":"https://openalex.org/keywords/interactome","display_name":"Interactome","score":0.7753852605819702},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6766284704208374},{"id":"https://openalex.org/keywords/protein\u2013protein-interaction","display_name":"Protein\u2013protein interaction","score":0.6376054286956787},{"id":"https://openalex.org/keywords/ensembl","display_name":"Ensembl","score":0.6119571328163147},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5794494152069092},{"id":"https://openalex.org/keywords/interaction-network","display_name":"Interaction network","score":0.5058164596557617},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.45442843437194824},{"id":"https://openalex.org/keywords/biological-data","display_name":"Biological data","score":0.4369087219238281},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.41100606322288513},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.36770564317703247},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.29840952157974243},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.292959064245224},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.2519010305404663},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.18904778361320496},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.18586060404777527}],"concepts":[{"id":"https://openalex.org/C2777002779","wikidata":"https://www.wikidata.org/wiki/Q42478","display_name":"Perl","level":2,"score":0.877906322479248},{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.7753852605819702},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6766284704208374},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.6376054286956787},{"id":"https://openalex.org/C141674004","wikidata":"https://www.wikidata.org/wiki/Q1344256","display_name":"Ensembl","level":5,"score":0.6119571328163147},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5794494152069092},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.5058164596557617},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.45442843437194824},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.4369087219238281},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.41100606322288513},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36770564317703247},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.29840952157974243},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.292959064245224},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2519010305404663},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.18904778361320496},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18586060404777527},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049750","descriptor_name":"Genome, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2105-12-289","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-289","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-289","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21767381","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21767381","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:pure.ed.ac.uk:openaire/9b8491f6-3e96-4545-96ff-49e9246a9bd5","is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/9b8491f6-3e96-4545-96ff-49e9246a9bd5","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gallone, G, Simpson, T I, Armstrong, J D & Jarman, A P 2011, 'Bio::Homology::InterologWalk - A Perl module to build putative protein-protein interaction networks through interolog mapping', BMC Bioinformatics, vol. 12, no. July, 289. https://doi.org/10.1186/1471-2105-12-289","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:ff1875d2f1d34d66b8e9cafbb40d855f","is_oa":false,"landing_page_url":"https://doaj.org/article/ff1875d2f1d34d66b8e9cafbb40d855f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 289 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2165851","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3161927","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:publications/9b8491f6-3e96-4545-96ff-49e9246a9bd5","is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.11820/9b8491f6-3e96-4545-96ff-49e9246a9bd5","pdf_url":null,"source":{"id":"https://openalex.org/S4406922455","display_name":"Edinburgh Research Explorer","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-289","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-289","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-289","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.4699999988079071,"display_name":"Life in Land"}],"awards":[{"id":"https://openalex.org/G3229750217","display_name":null,"funder_award_id":"BB/I004491/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G3567970989","display_name":"An integrated functional genomic approach to understanding gene regulation during neurogenesis.","funder_award_id":"077266","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4312828830","display_name":"A Systems Biological Approach to Elucidate Local Protein Synthesis Code in Plasticity and Memory","funder_award_id":"BB/I004491/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000787234.pdf","grobid_xml":"https://content.openalex.org/works/W2000787234.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1971155547","https://openalex.org/W1983079600","https://openalex.org/W1989991095","https://openalex.org/W1994547959","https://openalex.org/W1996490834","https://openalex.org/W1999895438","https://openalex.org/W2001291669","https://openalex.org/W2004163477","https://openalex.org/W2029158589","https://openalex.org/W2047253404","https://openalex.org/W2066235893","https://openalex.org/W2075122404","https://openalex.org/W2079818352","https://openalex.org/W2087609307","https://openalex.org/W2101181377","https://openalex.org/W2101783948","https://openalex.org/W2102155970","https://openalex.org/W2102162073","https://openalex.org/W2102225353","https://openalex.org/W2103017472","https://openalex.org/W2104315543","https://openalex.org/W2108238425","https://openalex.org/W2109248504","https://openalex.org/W2113019448","https://openalex.org/W2113613985","https://openalex.org/W2116117181","https://openalex.org/W2117513900","https://openalex.org/W2118128448","https://openalex.org/W2120211169","https://openalex.org/W2123501554","https://openalex.org/W2124463526","https://openalex.org/W2125179362","https://openalex.org/W2128036243","https://openalex.org/W2128900650","https://openalex.org/W2132023322","https://openalex.org/W2134506547","https://openalex.org/W2134711219","https://openalex.org/W2134878850","https://openalex.org/W2135688535","https://openalex.org/W2137492047","https://openalex.org/W2141652419","https://openalex.org/W2144014661","https://openalex.org/W2147068690","https://openalex.org/W2150934173","https://openalex.org/W2154662648","https://openalex.org/W2156340505","https://openalex.org/W2158439765","https://openalex.org/W2159675211","https://openalex.org/W2164328371","https://openalex.org/W2164813401","https://openalex.org/W2165253681","https://openalex.org/W2169228168","https://openalex.org/W2916767477","https://openalex.org/W2917375902","https://openalex.org/W2917431650","https://openalex.org/W3216627664","https://openalex.org/W4231056502","https://openalex.org/W4255852734"],"related_works":["https://openalex.org/W2122735960","https://openalex.org/W2012884498","https://openalex.org/W1739782975","https://openalex.org/W2114305343","https://openalex.org/W2101998831","https://openalex.org/W1922372990","https://openalex.org/W2086904135","https://openalex.org/W2032694615","https://openalex.org/W3016389020","https://openalex.org/W2157795344"],"abstract_inverted_index":{"BACKGROUND:":[0],"Protein-protein":[1],"interaction":[2,38,145,194,228,260],"(PPI)":[3],"data":[4,48,102,146,229,261],"are":[5,106,208,305],"widely":[6,53],"used":[7,70,163],"to":[8,14,49,59,80,95,127,147,164,180,231,234,278,289],"generate":[9,148,232],"network":[10],"models":[11],"that":[12,71,111,160,198,207],"aim":[13],"describe":[15],"the":[16,34,42,61,173,181,185,192,199,220,252,255,265,280,285,309,316],"relationships":[17],"between":[18,75],"proteins":[19,77],"in":[20,267],"biological":[21,97],"systems.":[22],"The":[23,139,269,297],"fidelity":[24],"and":[25,40,104,130,143,151,196,205,224,258,302],"completeness":[26],"of":[27,36,44,46,63,175,184,254,264],"such":[28],"networks":[29,195],"is":[30],"primarily":[31],"limited":[32],"by":[33,41,282],"paucity":[35],"protein":[37,227,259],"information":[39],"restriction":[43],"most":[45,88],"these":[47],"just":[50],"a":[51,113,124,240],"few":[52],"studied":[54],"experimental":[55,144,212],"organisms.":[56],"In":[57],"order":[58],"extend":[60],"utility":[62],"existing":[64,294],"PPIs,":[65],"computational":[66],"methods":[67,245],"can":[68,161],"be":[69,162,290],"exploit":[72],"functional":[73],"conservation":[74],"orthologous":[76],"across":[78],"taxa":[79],"predict":[81],"putative":[82,132,149,286],"PPIs":[83,150],"or":[84],"'interologs'.":[85],"To":[86],"date":[87,235],"interolog":[89,118,177,216,247],"prediction":[90,178,217,248],"efforts":[91],"have":[92],"been":[93],"restricted":[94],"specific":[96],"domains":[98],"with":[99],"fixed":[100],"underlying":[101],"sources":[103,230],"there":[105],"no":[107],"software":[108],"tools":[109],"available":[110,307],"provide":[112],"generalised":[114],"framework":[115],"for":[116,168,210,246,262],"'on-the-fly'":[117],"prediction.":[119],"RESULTS:":[120],"We":[121,171,190],"introduce":[122],"Bio::Homology::InterologWalk,":[123],"Perl":[125,222,311],"module":[126,140,270],"retrieve,":[128],"prioritise":[129,166],"visualise":[131],"protein-protein":[133],"interactions":[134,206],"through":[135],"an":[136,156],"orthology-walk":[137],"method.":[138],"uses":[141],"orthology":[142,257],"optionally":[152],"collates":[153],"meta-data":[154],"into":[155,293],"Interaction":[157],"Prioritisation":[158],"Index":[159],"help":[165],"interologs":[167,236],"further":[169],"analysis.":[170],"show":[172,197],"application":[174],"our":[176],"method":[179,200],"genomic":[182],"interactome":[183,203],"fruit":[186],"fly,":[187],"Drosophila":[188],"melanogaster.":[189],"analyse":[191],"resulting":[193],"proposes":[201],"new":[202],"members":[204],"candidates":[209],"future":[211],"investigation.":[213],"CONCLUSIONS:":[214],"Our":[215],"tool":[218],"employs":[219],"Ensembl":[221],"API":[223],"PSICQUIC":[225],"enabled":[226],"up":[233],"'on-the-fly'.":[237],"This":[238],"represents":[239],"significant":[241],"advance":[242],"on":[243],"previous":[244],"as":[249],"it":[250,276],"allows":[251],"use":[253],"latest":[256],"all":[263],"genomes":[266],"Ensembl.":[268],"outputs":[271],"simple":[272],"text":[273],"files,":[274],"making":[275],"easy":[277],"customise":[279],"results":[281],"post-processing,":[283],"allowing":[284],"PPI":[287],"datasets":[288],"easily":[291],"integrated":[292],"analysis":[295],"workflows.":[296],"Bio::Homology::InterologWalk":[298],"module,":[299],"sample":[300],"scripts":[301],"full":[303],"documentation":[304],"freely":[306],"from":[308],"Comprehensive":[310],"Archive":[312],"Network":[313],"(CPAN)":[314],"under":[315],"GNU":[317],"Public":[318],"license.":[319]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}