{"id":"https://openalex.org/W2040177576","doi":"https://doi.org/10.1186/1471-2105-12-239","title":"Noise reduction in protein-protein interaction graphs by the implementation of a novel weighting scheme","display_name":"Noise reduction in protein-protein interaction graphs by the implementation of a novel weighting scheme","publication_year":2011,"publication_date":"2011-06-16","ids":{"openalex":"https://openalex.org/W2040177576","doi":"https://doi.org/10.1186/1471-2105-12-239","mag":"2040177576","pmid":"https://pubmed.ncbi.nlm.nih.gov/21679454"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-12-239","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-239","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-239","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-239","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072675361","display_name":"George Kritikos","orcid":"https://orcid.org/0000-0003-1434-5176"},"institutions":[{"id":"https://openalex.org/I206127235","display_name":"Academy of Athens","ror":"https://ror.org/00qsdn986","country_code":"GR","type":"education","lineage":["https://openalex.org/I206127235"]},{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]},{"id":"https://openalex.org/I73142707","display_name":"Athens University of Economics and Business","ror":"https://ror.org/03s262162","country_code":"GR","type":"education","lineage":["https://openalex.org/I73142707"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George D Kritikos","raw_affiliation_strings":["Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Soranou Efesiou 4, GR-11527, Greece","Department of Informatics, Athens University of Economics & Business, Athens, Greece","Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Soranou Efesiou 4, GR-11527, Greece","institution_ids":["https://openalex.org/I206127235"]},{"raw_affiliation_string":"Department of Informatics, Athens University of Economics & Business, Athens, Greece","institution_ids":["https://openalex.org/I73142707"]},{"raw_affiliation_string":"Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021432827","display_name":"Charalampos Moschopoulos","orcid":null},"institutions":[{"id":"https://openalex.org/I174878644","display_name":"University of Patras","ror":"https://ror.org/017wvtq80","country_code":"GR","type":"education","lineage":["https://openalex.org/I174878644"]},{"id":"https://openalex.org/I206127235","display_name":"Academy of Athens","ror":"https://ror.org/00qsdn986","country_code":"GR","type":"education","lineage":["https://openalex.org/I206127235"]},{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Charalampos Moschopoulos","raw_affiliation_strings":["Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Soranou Efesiou 4, Athens, GR-11527, Greece","Pattern Recognition Lab, Department of Computer Engineering & Informatics, University of Patras, Patra, Rio, GR-26500, Greece","Pattern Recognition Lab, Department of Computer Engineering & Informatics, University of Patras, Patra, Rio, Greece","Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Soranou Efesiou 4, Athens, GR-11527, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]},{"raw_affiliation_string":"Pattern Recognition Lab, Department of Computer Engineering & Informatics, University of Patras, Patra, Rio, GR-26500, Greece","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Pattern Recognition Lab, Department of Computer Engineering & Informatics, University of Patras, Patra, Rio, Greece","institution_ids":["https://openalex.org/I174878644"]},{"raw_affiliation_string":"Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Athens, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057695979","display_name":"Michalis Vazirgiannis","orcid":"https://orcid.org/0000-0001-5923-4440"},"institutions":[{"id":"https://openalex.org/I12356871","display_name":"T\u00e9l\u00e9com Paris","ror":"https://ror.org/01naq7912","country_code":"FR","type":"education","lineage":["https://openalex.org/I12356871","https://openalex.org/I205703379","https://openalex.org/I4210145102"]},{"id":"https://openalex.org/I205703379","display_name":"Institut Mines-T\u00e9l\u00e9com","ror":"https://ror.org/025vp2923","country_code":"FR","type":"facility","lineage":["https://openalex.org/I205703379"]},{"id":"https://openalex.org/I73142707","display_name":"Athens University of Economics and Business","ror":"https://ror.org/03s262162","country_code":"GR","type":"education","lineage":["https://openalex.org/I73142707"]}],"countries":["FR","GR"],"is_corresponding":false,"raw_author_name":"Michalis Vazirgiannis","raw_affiliation_strings":["Department of Informatics, Athens University of Economics & Business, 76 Patision Street, Athens, GR-10434, Greece","D\u00e9partement Informatique et R\u00e9seaux, Institut T\u00e9l\u00e9com, Ecole de T\u00e9l\u00e9com ParisTech, Paris, France","Department of Informatics, Athens University of Economics & Business, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Informatics, Athens University of Economics & Business, 76 Patision Street, Athens, GR-10434, Greece","institution_ids":["https://openalex.org/I73142707"]},{"raw_affiliation_string":"D\u00e9partement Informatique et R\u00e9seaux, Institut T\u00e9l\u00e9com, Ecole de T\u00e9l\u00e9com ParisTech, Paris, France","institution_ids":["https://openalex.org/I12356871","https://openalex.org/I205703379"]},{"raw_affiliation_string":"Department of Informatics, Athens University of Economics & Business, Athens, Greece","institution_ids":["https://openalex.org/I73142707"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052164166","display_name":"\u03a3\u03bf\u03c6\u03af\u03b1 \u039a\u03bf\u03c3\u03c3\u03af\u03b4\u03b1","orcid":"https://orcid.org/0000-0002-8841-2864"},"institutions":[{"id":"https://openalex.org/I206127235","display_name":"Academy of Athens","ror":"https://ror.org/00qsdn986","country_code":"GR","type":"education","lineage":["https://openalex.org/I206127235"]},{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Sophia Kossida","raw_affiliation_strings":["Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Soranou Efesiou 4, Athens, GR-11527, Greece","Bioinformatics and Medical Informatics Team Biomedical Research Foundation of the Academy of Athens Athens Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Soranou Efesiou 4, Athens, GR-11527, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]},{"raw_affiliation_string":"Bioinformatics and Medical Informatics Team Biomedical Research Foundation of the Academy of Athens Athens Greece","institution_ids":["https://openalex.org/I206127235"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5052164166"],"corresponding_institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.3115,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.79131442,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"12","issue":"1","first_page":"239","last_page":"239"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interactome","display_name":"Interactome","score":0.9491368532180786},{"id":"https://openalex.org/keywords/weighting","display_name":"Weighting","score":0.8620287179946899},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7396999597549438},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7202116847038269},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5958536267280579},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.5492584109306335},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3879522979259491},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.33978569507598877},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3339760899543762},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3304746150970459},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12292876839637756}],"concepts":[{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.9491368532180786},{"id":"https://openalex.org/C183115368","wikidata":"https://www.wikidata.org/wiki/Q856577","display_name":"Weighting","level":2,"score":0.8620287179946899},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7396999597549438},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7202116847038269},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5958536267280579},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.5492584109306335},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3879522979259491},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.33978569507598877},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3339760899543762},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3304746150970459},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12292876839637756},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-12-239","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-239","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-239","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21679454","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21679454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:HAL:hal-04112790v1","is_oa":true,"landing_page_url":"https://hal.science/hal-04112790","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, 2011, 12 (1), pp.239. &#x27E8;10.1186/1471-2105-12-239&#x27E9;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:42d4ec137e8b4f12a2dbe8ed1b5277ca","is_oa":false,"landing_page_url":"https://doaj.org/article/42d4ec137e8b4f12a2dbe8ed1b5277ca","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 12, Iss 1, p 239 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2239530","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3230908","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-12-239","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-12-239","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-12-239","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310412","display_name":"Athens University of Economics and Business","ror":"https://ror.org/03s262162"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2040177576.pdf","grobid_xml":"https://content.openalex.org/works/W2040177576.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1587057986","https://openalex.org/W1589825577","https://openalex.org/W1663973292","https://openalex.org/W1783384641","https://openalex.org/W1956694423","https://openalex.org/W1959178355","https://openalex.org/W1981276685","https://openalex.org/W1986214964","https://openalex.org/W1987363726","https://openalex.org/W1987741645","https://openalex.org/W2037442572","https://openalex.org/W2073459066","https://openalex.org/W2100585269","https://openalex.org/W2103017472","https://openalex.org/W2113654464","https://openalex.org/W2117513900","https://openalex.org/W2121470019","https://openalex.org/W2121564430","https://openalex.org/W2123318061","https://openalex.org/W2130687290","https://openalex.org/W2131323902","https://openalex.org/W2132914434","https://openalex.org/W2134711219","https://openalex.org/W2134962976","https://openalex.org/W2136850043","https://openalex.org/W2137786672","https://openalex.org/W2138003801","https://openalex.org/W2140280811","https://openalex.org/W2141682941","https://openalex.org/W2150934340","https://openalex.org/W2152336513","https://openalex.org/W2152495216","https://openalex.org/W2152653671","https://openalex.org/W2155723007","https://openalex.org/W2159843086","https://openalex.org/W2161062388","https://openalex.org/W2163485494","https://openalex.org/W2165874743","https://openalex.org/W2166525781","https://openalex.org/W2171403830","https://openalex.org/W2999905431","https://openalex.org/W3106276089","https://openalex.org/W4212863985","https://openalex.org/W4246925013"],"related_works":["https://openalex.org/W4292634579","https://openalex.org/W2964314049","https://openalex.org/W2022326234","https://openalex.org/W1531941329","https://openalex.org/W4388694323","https://openalex.org/W3215098729","https://openalex.org/W4243081378","https://openalex.org/W1979330259","https://openalex.org/W2622356054","https://openalex.org/W2804670115"],"abstract_inverted_index":{"BACKGROUND:":[0],"Recent":[1],"technological":[2],"advances":[3],"applied":[4],"to":[5,18,42,65,85,97,131],"biology":[6],"such":[7,46],"as":[8,47,163,165],"yeast-two-hybrid,":[9],"phage":[10],"display":[11],"and":[12,82,120],"mass":[13],"spectrometry":[14],"have":[15,55],"enabled":[16],"us":[17],"create":[19],"a":[20,31,78,108,142,146],"detailed":[21],"map":[22],"of":[23,36,160,168,191,206,218],"protein":[24,48,181],"interaction":[25,28,51,124,144],"networks.":[26],"These":[27],"networks":[29,174],"represent":[30],"rich,":[32],"yet":[33],"noisy,":[34],"source":[35],"data":[37],"that":[38,141,196],"could":[39],"be":[40],"used":[41],"extract":[43],"meaningful":[44],"information,":[45],"complexes.":[49],"Several":[50],"network":[52],"weighting":[53,80,126,199,213],"schemes":[54],"been":[56],"proposed":[57,212],"so":[58],"far":[59],"in":[60,63,70,157,184],"the":[61,67,86,101,113,132,138,158,179,185,203],"literature":[62],"order":[64],"eliminate":[66],"noise":[68],"inherent":[69],"interactome":[71,134,173,197],"data.":[72],"In":[73],"this":[74],"paper,":[75],"we":[76],"propose":[77],"novel":[79,119],"scheme":[81,214],"apply":[83],"it":[84],"S.":[87],"cerevisiae":[88],"interactome.":[89],"Complex":[90],"prediction":[91],"rates":[92],"are":[93,129,175],"improved":[94],"by":[95,116],"up":[96],"39%,":[98],"depending":[99],"on":[100,137],"clustering":[102,153,204,208],"algorithm":[103],"applied.":[104],"RESULTS:":[105],"We":[106],"adopt":[107],"two":[109,166],"step":[110,151],"procedure.":[111],"During":[112],"first":[114],"step,":[115],"applying":[117],"both":[118],"well":[121,164],"established":[122,155],"protein-protein":[123],"(PPI)":[125],"methods,":[127],"weights":[128],"introduced":[130],"original":[133],"graph":[135,161,198,220],"based":[136],"confidence":[139],"level":[140],"given":[143],"is":[145],"true-positive":[147],"one.":[148],"The":[149,171,189],"second":[150],"applies":[152],"using":[154],"algorithms":[156],"field":[159],"theory,":[162],"variations":[167],"Spectral":[169],"clustering.":[170],"clustered":[172],"also":[176],"cross-validated":[177],"against":[178],"confirmed":[180],"complexes":[182],"present":[183],"MIPS":[186],"database.":[187],"CONCLUSIONS:":[188],"results":[190,205],"our":[192,211],"experimental":[193],"work":[194],"demonstrate":[195],"methods":[200],"clearly":[201],"improve":[202],"several":[207],"algorithms.":[209],"Moreover,":[210],"outperforms":[215],"other":[216],"approaches":[217],"PPI":[219],"weighting.":[221]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}
