{"id":"https://openalex.org/W2125479651","doi":"https://doi.org/10.1186/1471-2105-11-53","title":"Global screening of potential Candida albicans biofilm-related transcription factors via network comparison","display_name":"Global screening of potential Candida albicans biofilm-related transcription factors via network comparison","publication_year":2010,"publication_date":"2010-01-26","ids":{"openalex":"https://openalex.org/W2125479651","doi":"https://doi.org/10.1186/1471-2105-11-53","mag":"2125479651","pmid":"https://pubmed.ncbi.nlm.nih.gov/20102611"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-11-53","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-53","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-53","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-53","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100733708","display_name":"Yu\u2010Chao Wang","orcid":"https://orcid.org/0000-0002-1574-1691"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yu-Chao Wang","raw_affiliation_strings":["Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan","Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000109074","display_name":"Chung\u2010Yu Lan","orcid":"https://orcid.org/0000-0002-1533-3049"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chung-Yu Lan","raw_affiliation_strings":["Department of Life Science, National Tsing Hua University, Hsinchu, 30013, Taiwan","Institute of Molecular and Cell Biology, National Tsing Hua University, Hsinchu, 30013, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, National Tsing Hua University, Hsinchu, 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"Institute of Molecular and Cell Biology, National Tsing Hua University, Hsinchu, 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113540585","display_name":"Wen-Ping Hsieh","orcid":null},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Ping Hsieh","raw_affiliation_strings":["Institute of Statistics, National Tsing Hua University, Hsinchu, 30013, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Statistics, National Tsing Hua University, Hsinchu, 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059122266","display_name":"Luis A. Murillo","orcid":"https://orcid.org/0000-0002-5918-8584"},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luis A Murillo","raw_affiliation_strings":["Department of Cell and Tissue Biology, University of California, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Tissue Biology, University of California, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083244256","display_name":"Nina Agabian","orcid":null},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nina Agabian","raw_affiliation_strings":["Department of Cell and Tissue Biology, University of California, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Tissue Biology, University of California, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113540586","display_name":"Bor-Sen Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Bor-Sen Chen","raw_affiliation_strings":["Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100733708"],"corresponding_institution_ids":["https://openalex.org/I25846049"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":3.0911,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.91639955,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"11","issue":"1","first_page":"53","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7613999843597412,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7613999843597412,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.10010000318288803,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.037700001150369644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biofilm","display_name":"Biofilm","score":0.9626049995422363},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.838233470916748},{"id":"https://openalex.org/keywords/corpus-albicans","display_name":"Corpus albicans","score":0.7282606959342957},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.657936692237854},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.590613842010498},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5510134696960449},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5387343764305115},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.5282555818557739},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5262600183486938},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5229492783546448},{"id":"https://openalex.org/keywords/virulence-factor","display_name":"Virulence factor","score":0.503375232219696},{"id":"https://openalex.org/keywords/virulence","display_name":"Virulence","score":0.4749574661254883},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.4392586946487427},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.34317857027053833},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.3271617293357849},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.1570916473865509}],"concepts":[{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.9626049995422363},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.838233470916748},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.7282606959342957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.657936692237854},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.590613842010498},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5510134696960449},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5387343764305115},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5282555818557739},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5262600183486938},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5229492783546448},{"id":"https://openalex.org/C2781090273","wikidata":"https://www.wikidata.org/wiki/Q1623405","display_name":"Virulence factor","level":4,"score":0.503375232219696},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.4749574661254883},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4392586946487427},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34317857027053833},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3271617293357849},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.1570916473865509}],"mesh":[{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-11-53","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-53","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-53","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20102611","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20102611","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:609f9285005e41a3a09a98acec84c00f","is_oa":false,"landing_page_url":"https://doaj.org/article/609f9285005e41a3a09a98acec84c00f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 11, Iss 1, p 53 (2010)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2842261","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2842261","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-11-53","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-53","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-53","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8135589557","display_name":null,"funder_award_id":"NSC 97-2627-B-007-001","funder_id":"https://openalex.org/F4320321040","funder_display_name":"National Science Council"}],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2125479651.pdf","grobid_xml":"https://content.openalex.org/works/W2125479651.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W40369685","https://openalex.org/W1496736275","https://openalex.org/W1500387969","https://openalex.org/W1509452146","https://openalex.org/W1599969036","https://openalex.org/W1602240847","https://openalex.org/W1981442035","https://openalex.org/W1990317593","https://openalex.org/W1990987722","https://openalex.org/W1994243942","https://openalex.org/W1999340863","https://openalex.org/W2000502211","https://openalex.org/W2004199685","https://openalex.org/W2004817797","https://openalex.org/W2011551551","https://openalex.org/W2015012952","https://openalex.org/W2019012779","https://openalex.org/W2020339002","https://openalex.org/W2026341138","https://openalex.org/W2041251634","https://openalex.org/W2046255935","https://openalex.org/W2049046860","https://openalex.org/W2049219353","https://openalex.org/W2049505636","https://openalex.org/W2061291780","https://openalex.org/W2061448692","https://openalex.org/W2066976786","https://openalex.org/W2067409920","https://openalex.org/W2080498142","https://openalex.org/W2096145311","https://openalex.org/W2102387530","https://openalex.org/W2103017472","https://openalex.org/W2112595354","https://openalex.org/W2112987407","https://openalex.org/W2121905508","https://openalex.org/W2127788692","https://openalex.org/W2127988357","https://openalex.org/W2129508575","https://openalex.org/W2134714928","https://openalex.org/W2139047628","https://openalex.org/W2142045367","https://openalex.org/W2142635246","https://openalex.org/W2146513423","https://openalex.org/W2151757612","https://openalex.org/W2153283265","https://openalex.org/W2153533521","https://openalex.org/W2155560009","https://openalex.org/W2161477969","https://openalex.org/W2162559963","https://openalex.org/W2164315014","https://openalex.org/W2167460646","https://openalex.org/W2167553361","https://openalex.org/W2167798305","https://openalex.org/W2169101569","https://openalex.org/W2171548303","https://openalex.org/W3149745985","https://openalex.org/W3173138228","https://openalex.org/W4213354399","https://openalex.org/W4233235616","https://openalex.org/W4236316114","https://openalex.org/W4297932385"],"related_works":["https://openalex.org/W2102861863","https://openalex.org/W2367173716","https://openalex.org/W2247003880","https://openalex.org/W4362508968","https://openalex.org/W3029732278","https://openalex.org/W2778267304","https://openalex.org/W2742010288","https://openalex.org/W4309514212","https://openalex.org/W2347270899","https://openalex.org/W4252342766"],"abstract_inverted_index":{"BACKGROUND:":[0],"Candida":[1],"albicans":[2,22,87,131,255],"is":[3,15,25],"a":[4,16,117,143,223],"commonly":[5],"encountered":[6],"fungal":[7],"pathogen":[8],"in":[9,20,105,240],"humans.":[10],"The":[11,136,190],"formation":[12,46],"of":[13,30,72,80,129,145,157,159,168,181,253],"biofilm":[14,37,45,88,132,164,178,241],"major":[17],"virulence":[18],"factor":[19],"C.":[21,86,106,130,254],"pathogenesis":[23],"and":[24,93,113,133,142,153,205],"related":[26,175],"to":[27,49,98,123,151,173,176,235],"antidrug":[28],"resistance":[29],"this":[31,54,217],"organism.":[32],"Although":[33],"many":[34,208],"factors":[35,83],"affecting":[36],"have":[38,211],"been":[39,213],"analyzed,":[40],"molecular":[41],"mechanisms":[42,239],"that":[43,193,210,227],"regulate":[44],"still":[47],"await":[48],"be":[50,174,220],"elucidated.":[51],"RESULTS:":[52],"In":[53],"study,":[55],"from":[56,74],"the":[57,100,125,155,177,194,237,247],"gene":[58,114,126],"regulatory":[59,103,111,127,238],"network":[60],"perspective,":[61],"we":[62],"developed":[63],"an":[64],"efficient":[65],"computational":[66],"framework,":[67],"which":[68,243],"integrates":[69],"different":[70],"kinds":[71],"data":[73,95],"genome-scale":[75],"analysis,":[76],"for":[77,232,250],"global":[78],"screening":[79,196,225],"potential":[81,161],"transcription":[82],"(TFs)":[84],"controlling":[85],"formation.":[89,165],"S.":[90],"cerevisiae":[91],"information":[92],"ortholog":[94],"were":[96,139],"used":[97],"infer":[99],"possible":[101],"TF-gene":[102,110],"associations":[104,112],"albicans.":[107],"Based":[108],"on":[109],"expression":[115],"profiles,":[116],"stochastic":[118],"dynamic":[119],"model":[120],"was":[121,149],"employed":[122,221],"reconstruct":[124],"networks":[128,138],"planktonic":[134],"cells.":[135],"two":[137],"then":[140],"compared":[141],"score":[144],"relevance":[146],"value":[147],"(RV)":[148],"proposed":[150,195],"determine":[152],"assign":[154],"quantity":[156],"correlation":[158],"each":[160],"TF":[162],"with":[163],"A":[166],"total":[167],"twenty-three":[169],"TFs":[170,204],"are":[171,183],"identified":[172],"formation;":[179],"ten":[180],"them":[182],"previously":[184,214],"reported":[185],"by":[186],"literature":[187],"evidences.":[188],"CONCLUSIONS:":[189],"results":[191],"indicate":[192],"method":[197,218],"can":[198,219,244],"successfully":[199],"identify":[200,207],"most":[201],"known":[202],"biofilm-related":[203],"also":[206],"others":[209],"not":[212],"reported.":[215],"Together,":[216],"as":[222,246],"pre-experiment":[224],"approach":[226],"reveals":[228],"new":[229],"target":[230],"genes":[231],"further":[233],"characterization":[234],"understand":[236],"formation,":[242],"serve":[245],"starting":[248],"point":[249],"therapeutic":[251],"intervention":[252],"infections.":[256]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}