{"id":"https://openalex.org/W2118112532","doi":"https://doi.org/10.1186/1471-2105-11-526","title":"A statistical approach to finding overlooked genetic associations","display_name":"A statistical approach to finding overlooked genetic associations","publication_year":2010,"publication_date":"2010-10-21","ids":{"openalex":"https://openalex.org/W2118112532","doi":"https://doi.org/10.1186/1471-2105-11-526","mag":"2118112532","pmid":"https://pubmed.ncbi.nlm.nih.gov/20964847"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-11-526","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-526","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-526","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-526","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086304683","display_name":"Andrew K. Rider","orcid":null},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew K Rider","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA","Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081185204","display_name":"Geoffrey Siwo","orcid":"https://orcid.org/0000-0003-0726-997X"},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Geoffrey Siwo","raw_affiliation_strings":["Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","Department of Biological Sciences, University of Notre Dame, Notre Dame, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Biological Sciences, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068157871","display_name":"Nitesh V. Chawla","orcid":"https://orcid.org/0000-0003-3932-5956"},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nitesh V Chawla","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, Indiana, USA","Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA","Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072425194","display_name":"Michael T. Ferdig","orcid":"https://orcid.org/0000-0003-3516-9829"},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Ferdig","raw_affiliation_strings":["Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, Indiana, USA","Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","Department of Biological Sciences, University of Notre Dame, Notre Dame, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Biological Sciences, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019857186","display_name":"Scott Emrich","orcid":"https://orcid.org/0000-0002-5741-4517"},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott J Emrich","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Eck Institute for Global Health, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, USA","institution_ids":["https://openalex.org/I107639228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5019857186"],"corresponding_institution_ids":["https://openalex.org/I107639228"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.3785,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.69681463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"11","issue":"1","first_page":"526","last_page":"526"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/expression-quantitative-trait-loci","display_name":"Expression quantitative trait loci","score":0.8900446891784668},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6792902946472168},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.6178801655769348},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5685877799987793},{"id":"https://openalex.org/keywords/trait","display_name":"Trait","score":0.541895866394043},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5377284288406372},{"id":"https://openalex.org/keywords/genetic-architecture","display_name":"Genetic architecture","score":0.4846135079860687},{"id":"https://openalex.org/keywords/quantitative-trait-locus","display_name":"Quantitative trait locus","score":0.47554418444633484},{"id":"https://openalex.org/keywords/locus","display_name":"Locus (genetics)","score":0.4738861918449402},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.45763683319091797},{"id":"https://openalex.org/keywords/false-discovery-rate","display_name":"False discovery rate","score":0.4428621530532837},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4310036301612854},{"id":"https://openalex.org/keywords/multiple-comparisons-problem","display_name":"Multiple comparisons problem","score":0.4198909401893616},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3354191184043884},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.18790912628173828},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.186146080493927},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.12661853432655334},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.09195172786712646},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.0728762149810791}],"concepts":[{"id":"https://openalex.org/C168393362","wikidata":"https://www.wikidata.org/wiki/Q5421706","display_name":"Expression quantitative trait loci","level":5,"score":0.8900446891784668},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6792902946472168},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.6178801655769348},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5685877799987793},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.541895866394043},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5377284288406372},{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.4846135079860687},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.47554418444633484},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.4738861918449402},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.45763683319091797},{"id":"https://openalex.org/C193244246","wikidata":"https://www.wikidata.org/wiki/Q5432696","display_name":"False discovery rate","level":3,"score":0.4428621530532837},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4310036301612854},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.4198909401893616},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3354191184043884},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.18790912628173828},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.186146080493927},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12661853432655334},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.09195172786712646},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0728762149810791},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-11-526","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-526","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-526","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20964847","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20964847","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:2419c6d2dcee42dbb7178d7acbce5cfa","is_oa":true,"landing_page_url":"https://doaj.org/article/2419c6d2dcee42dbb7178d7acbce5cfa","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 11, Iss 1, p 526 (2010)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2974753","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2974753","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-11-526","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-11-526","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-11-526","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.699999988079071}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309292","display_name":"Princeton University","ror":"https://ror.org/00hx57361"},{"id":"https://openalex.org/F4320310260","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2118112532.pdf","grobid_xml":"https://content.openalex.org/works/W2118112532.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1583837637","https://openalex.org/W1647729745","https://openalex.org/W1999722941","https://openalex.org/W2055672407","https://openalex.org/W2066669827","https://openalex.org/W2094248448","https://openalex.org/W2108334325","https://openalex.org/W2125860227","https://openalex.org/W2134537390","https://openalex.org/W2140948740","https://openalex.org/W2148860875","https://openalex.org/W2159420567","https://openalex.org/W2166574880"],"related_works":["https://openalex.org/W2467227750","https://openalex.org/W4293336298","https://openalex.org/W2093104131","https://openalex.org/W4300887971","https://openalex.org/W2178204436","https://openalex.org/W2143079975","https://openalex.org/W2026085942","https://openalex.org/W2333750400","https://openalex.org/W2949247377","https://openalex.org/W2766106220"],"abstract_inverted_index":{"New":[0],"eQTLs":[1],"and":[2],"hotspots":[3],"found":[4],"with":[5],"this":[6],"method":[7],"may":[8],"represent":[9],"regions":[10],"of":[11,28],"the":[12],"genome":[13],"or":[14],"biological":[15],"processes":[16],"that":[17],"are":[18],"controlled":[19],"through":[20],"few":[21],"relatively":[22],"strong":[23],"genetic":[24],"interactions.":[25],"These":[26],"points":[27],"interest":[29],"warrant":[30],"experimental":[31],"investigation.":[32]},"counts_by_year":[{"year":2012,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}