{"id":"https://openalex.org/W2038963685","doi":"https://doi.org/10.1186/1471-2105-10-48","title":"GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists","display_name":"GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists","publication_year":2009,"publication_date":"2009-02-03","ids":{"openalex":"https://openalex.org/W2038963685","doi":"https://doi.org/10.1186/1471-2105-10-48","mag":"2038963685","pmid":"https://pubmed.ncbi.nlm.nih.gov/19192299"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-10-48","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-48","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-48","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-48","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110815848","display_name":"Eran Eden","orcid":null},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Eran Eden","raw_affiliation_strings":["Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel. eraneden@gmail.com","Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel. eraneden@gmail.com","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019735460","display_name":"Roy Navon","orcid":"https://orcid.org/0000-0001-7738-6915"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Roy Navon","raw_affiliation_strings":["Agilent Laboratories, Tel-Aviv, Israel","School of Computer Science, Tel Aviv University, Tel Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Laboratories, Tel-Aviv, Israel","institution_ids":[]},{"raw_affiliation_string":"School of Computer Science, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086399308","display_name":"Israel Steinfeld","orcid":null},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Israel Steinfeld","raw_affiliation_strings":["Agilent Laboratories, Tel-Aviv, Israel","Computer Science Department, Technion, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Laboratories, Tel-Aviv, Israel","institution_ids":[]},{"raw_affiliation_string":"Computer Science Department, Technion, Haifa, Israel","institution_ids":["https://openalex.org/I174306211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029183165","display_name":"Doron Lipson","orcid":"https://orcid.org/0009-0004-2738-5702"},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Doron Lipson","raw_affiliation_strings":["Computer Science Department, Technion, Haifa, Israel","Computer Science Department Technion Haifa Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Technion, Haifa, Israel","institution_ids":["https://openalex.org/I174306211"]},{"raw_affiliation_string":"Computer Science Department Technion Haifa Israel","institution_ids":["https://openalex.org/I174306211"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002511176","display_name":"Zohar Yakhini","orcid":"https://orcid.org/0000-0002-0420-5412"},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Zohar Yakhini","raw_affiliation_strings":["Agilent Laboratories, Tel-Aviv, Israel","Computer Science Department, Technion, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Laboratories, Tel-Aviv, Israel","institution_ids":[]},{"raw_affiliation_string":"Computer Science Department, Technion, Haifa, Israel","institution_ids":["https://openalex.org/I174306211"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5110815848"],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":20.6709,"has_fulltext":true,"cited_by_count":3671,"citation_normalized_percentile":{"value":0.99685467,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"10","issue":"1","first_page":"48","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.45719999074935913,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.45719999074935913,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.3993000090122223,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10538","display_name":"Data Mining Algorithms and Applications","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.6698667407035828},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6199043989181519},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.539923369884491},{"id":"https://openalex.org/keywords/variety","display_name":"Variety (cybernetics)","score":0.5374363660812378},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.49788808822631836},{"id":"https://openalex.org/keywords/gorilla","display_name":"Gorilla","score":0.48818403482437134},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.46748417615890503},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.44965529441833496},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.42957544326782227},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.39341962337493896},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.36523932218551636},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.24644210934638977},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23900574445724487},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2233906388282776},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1685471534729004}],"concepts":[{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.6698667407035828},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6199043989181519},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.539923369884491},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.5374363660812378},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.49788808822631836},{"id":"https://openalex.org/C2777477413","wikidata":"https://www.wikidata.org/wiki/Q36611","display_name":"Gorilla","level":2,"score":0.48818403482437134},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.46748417615890503},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.44965529441833496},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.42957544326782227},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.39341962337493896},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36523932218551636},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24644210934638977},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23900574445724487},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2233906388282776},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1685471534729004},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009626","descriptor_name":"Terminology as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009626","descriptor_name":"Terminology as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009626","descriptor_name":"Terminology as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2105-10-48","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-48","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-48","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19192299","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19192299","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:doi:10.5281/zenodo.13526058","is_oa":true,"landing_page_url":"https://zotero.org/groups/5435545/items/AMCFMSE8","pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"pmh:oai:doaj.org/article:6fbf3642915b41c2a1cd65f3734dbd96","is_oa":false,"landing_page_url":"https://doaj.org/article/6fbf3642915b41c2a1cd65f3734dbd96","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 10, Iss 1, p 48 (2009)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2644678","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2644678","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-10-48","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-48","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-48","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2038963685.pdf","grobid_xml":"https://content.openalex.org/works/W2038963685.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1912468900","https://openalex.org/W1981093360","https://openalex.org/W1997921822","https://openalex.org/W2001914359","https://openalex.org/W2049527386","https://openalex.org/W2096561521","https://openalex.org/W2102992354","https://openalex.org/W2103017472","https://openalex.org/W2121824548","https://openalex.org/W2122683221","https://openalex.org/W2124388496","https://openalex.org/W2128985829","https://openalex.org/W2130410032","https://openalex.org/W2134736660","https://openalex.org/W2135230352","https://openalex.org/W2138247507","https://openalex.org/W2139703939","https://openalex.org/W2166574880","https://openalex.org/W2171030481","https://openalex.org/W2412256481","https://openalex.org/W4238387639"],"related_works":["https://openalex.org/W2038655931","https://openalex.org/W2011926203","https://openalex.org/W1989889255","https://openalex.org/W2800651838","https://openalex.org/W2914418582","https://openalex.org/W2069460348","https://openalex.org/W2086833343","https://openalex.org/W4248905937","https://openalex.org/W2166164680","https://openalex.org/W4235950041"],"abstract_inverted_index":{"BACKGROUND:":[0],"Since":[1],"the":[2,5,21,58,63,91,111,166,180,191,201,226,240,263],"inception":[3],"of":[4,11,28,39,48,107,139,144,147,168,179,210,212,216,221,225,239,266],"GO":[6,22,32,102,159,217,244,251,267],"annotation":[7],"project,":[8],"a":[9,26,45,51,96,136,152,169,175,232,236,259],"variety":[10,27],"tools":[12,29,41,68,280],"have":[13],"been":[14],"developed":[15],"that":[16,30,71,99,161,257],"support":[17,72],"exploring":[18],"and":[19,50,54,117,214,273,287],"searching":[20],"database.":[23],"In":[24],"particular,":[25],"perform":[31],"enrichment":[33,56,227,268,279],"analysis":[34,209,228,252],"are":[35,162],"currently":[36],"available.":[37],"Most":[38],"these":[40],"require":[42],"as":[43,135,231],"input":[44],"target":[46,59,116],"set":[47,53,60],"genes":[49,140,213],"background":[52,64,118],"seek":[55],"in":[57,104,124,219],"compared":[61],"to":[62,90,113,157,262],"set.":[65],"A":[66],"few":[67],"also":[69],"exist":[70],"analyzing":[73],"ranked":[74,105,137,170],"lists.":[75],"The":[76,223],"latter":[77],"typically":[78],"rely":[79],"on":[80,83,174],"simulations":[81],"or":[82,146],"union-bound":[84],"correction":[85],"for":[86,190,203],"assigning":[87],"statistical":[88,155,208],"significance":[89],"results.":[92],"RESULTS:":[93],"GOrilla":[94,150,185,247,292],"is":[95,121,229,248,293],"web-based":[97],"application":[98],"identifies":[100],"enriched":[101,164,243],"terms":[103,160,218],"lists":[106],"genes,":[108],"without":[109,200],"requiring":[110],"user":[112],"provide":[114],"explicit":[115],"sets.":[119],"This":[120,205],"particularly":[122],"useful":[123,260],"many":[125],"typical":[126],"cases":[127],"where":[128],"genomic":[129],"data":[130],"may":[131],"be":[132],"naturally":[133],"represented":[134],"list":[138],"(e.g.":[141],"by":[142],"level":[143],"expression":[145],"differential":[148],"expression).":[149],"employs":[151],"flexible":[153],"threshold":[154,195,277],"approach":[156],"discover":[158],"significantly":[163],"at":[165],"top":[167],"gene":[171],"list.":[172],"Building":[173],"complete":[176],"theoretical":[177],"characterization":[178],"underlying":[181],"distribution,":[182],"called":[183],"mHG,":[184],"computes":[186],"an":[187,249,288],"exact":[188],"p-value":[189],"observed":[192],"enrichment,":[193],"taking":[194],"multiple":[196],"testing":[197],"into":[198],"account":[199],"need":[202],"simulations.":[204],"enables":[206],"rigorous":[207,282],"thousand":[211],"thousands":[215],"order":[220],"seconds.":[222],"output":[224],"visualized":[230],"hierarchical":[233],"structure,":[234],"providing":[235],"clear":[237],"view":[238],"relations":[241],"between":[242],"terms.":[245],"CONCLUSION:":[246],"efficient":[250],"tool":[253],"with":[254],"unique":[255,271],"features":[256,272],"make":[258],"addition":[261],"existing":[264],"repertoire":[265],"tools.":[269],"GOrilla's":[270],"advantages":[274],"over":[275],"other":[276],"free":[278],"include":[281],"statistics,":[283],"fast":[284],"running":[285],"time":[286],"effective":[289],"graphical":[290],"representation.":[291],"publicly":[294],"available":[295],"at:":[296],"http://cbl-gorilla.cs.technion.ac.il":[297]},"counts_by_year":[{"year":2026,"cited_by_count":31},{"year":2025,"cited_by_count":144},{"year":2024,"cited_by_count":219},{"year":2023,"cited_by_count":241},{"year":2022,"cited_by_count":286},{"year":2021,"cited_by_count":490},{"year":2020,"cited_by_count":371},{"year":2019,"cited_by_count":353},{"year":2018,"cited_by_count":333},{"year":2017,"cited_by_count":273},{"year":2016,"cited_by_count":246},{"year":2015,"cited_by_count":221},{"year":2014,"cited_by_count":170},{"year":2013,"cited_by_count":140},{"year":2012,"cited_by_count":67}],"updated_date":"2026-06-05T09:01:59.212387","created_date":"2025-10-10T00:00:00"}