{"id":"https://openalex.org/W2136172853","doi":"https://doi.org/10.1186/1471-2105-10-261","title":"Computing power of quantitative trait locus association mapping for haploid loci","display_name":"Computing power of quantitative trait locus association mapping for haploid loci","publication_year":2009,"publication_date":"2009-08-23","ids":{"openalex":"https://openalex.org/W2136172853","doi":"https://doi.org/10.1186/1471-2105-10-261","mag":"2136172853","pmid":"https://pubmed.ncbi.nlm.nih.gov/19698182"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2105-10-261","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-261","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-261","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-261","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072310267","display_name":"Derek Gordon","orcid":"https://orcid.org/0000-0003-2945-1748"},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Derek Gordon","raw_affiliation_strings":["Department of Genetics, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA. gordon@biology.rutgers.edu","Dept. of Genetics, Rutgers University, Piscataway, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genetics, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA. gordon@biology.rutgers.edu","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Dept. of Genetics, Rutgers University, Piscataway, USA","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072202042","display_name":"Andrew R. Zinn","orcid":"https://orcid.org/0000-0002-4935-3291"},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"education","lineage":["https://openalex.org/I867280407"]},{"id":"https://openalex.org/I4210096815","display_name":"Southwestern Medical Center","ror":"https://ror.org/00t9vx427","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096815"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew R Zinn","raw_affiliation_strings":["McDermott Center for Human Growth and Development, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX, 75390-8591, USA","McDermott Center for Human Growth and Development, University of Texas Southwestern Medical School, Dallas, USA"],"affiliations":[{"raw_affiliation_string":"McDermott Center for Human Growth and Development, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX, 75390-8591, USA","institution_ids":["https://openalex.org/I4210096815","https://openalex.org/I867280407"]},{"raw_affiliation_string":"McDermott Center for Human Growth and Development, University of Texas Southwestern Medical School, Dallas, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5072310267"],"corresponding_institution_ids":["https://openalex.org/I102322142"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.18772166,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"10","issue":"1","first_page":"261","last_page":"261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11229","display_name":"Genetics and Plant Breeding","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/locus","display_name":"Locus (genetics)","score":0.7721624374389648},{"id":"https://openalex.org/keywords/quantitative-trait-locus","display_name":"Quantitative trait locus","score":0.7267166376113892},{"id":"https://openalex.org/keywords/ploidy","display_name":"Ploidy","score":0.6809921860694885},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6749993562698364},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6609116196632385},{"id":"https://openalex.org/keywords/doubled-haploidy","display_name":"Doubled haploidy","score":0.603194534778595},{"id":"https://openalex.org/keywords/biometrics","display_name":"Biometrics","score":0.5025844573974609},{"id":"https://openalex.org/keywords/statistical-power","display_name":"Statistical power","score":0.4852125942707062},{"id":"https://openalex.org/keywords/association-mapping","display_name":"Association mapping","score":0.47948703169822693},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46652159094810486},{"id":"https://openalex.org/keywords/gene-mapping","display_name":"Gene mapping","score":0.41862958669662476},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.35076773166656494},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.24237021803855896},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.23258885741233826},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1890944242477417},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.14566540718078613},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.1324470043182373},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.10321217775344849},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.09231767058372498}],"concepts":[{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.7721624374389648},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.7267166376113892},{"id":"https://openalex.org/C143191323","wikidata":"https://www.wikidata.org/wiki/Q118406","display_name":"Ploidy","level":3,"score":0.6809921860694885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6749993562698364},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6609116196632385},{"id":"https://openalex.org/C34827325","wikidata":"https://www.wikidata.org/wiki/Q3037604","display_name":"Doubled haploidy","level":4,"score":0.603194534778595},{"id":"https://openalex.org/C184297639","wikidata":"https://www.wikidata.org/wiki/Q177765","display_name":"Biometrics","level":2,"score":0.5025844573974609},{"id":"https://openalex.org/C96608239","wikidata":"https://www.wikidata.org/wiki/Q1199823","display_name":"Statistical power","level":2,"score":0.4852125942707062},{"id":"https://openalex.org/C134443026","wikidata":"https://www.wikidata.org/wiki/Q4809584","display_name":"Association mapping","level":5,"score":0.47948703169822693},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46652159094810486},{"id":"https://openalex.org/C122735190","wikidata":"https://www.wikidata.org/wiki/Q715789","display_name":"Gene mapping","level":4,"score":0.41862958669662476},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.35076773166656494},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.24237021803855896},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.23258885741233826},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1890944242477417},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.14566540718078613},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.1324470043182373},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.10321217775344849},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.09231767058372498}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006238","descriptor_name":"Haploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006238","descriptor_name":"Haploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006238","descriptor_name":"Haploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2105-10-261","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-261","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-261","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19698182","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19698182","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:bdbf3dacea9e409fb674986e50f49afa","is_oa":true,"landing_page_url":"https://doaj.org/article/bdbf3dacea9e409fb674986e50f49afa","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Bioinformatics, Vol 10, Iss 1, p 261 (2009)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:1876082","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2738682","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1471-2105-10-261","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2105-10-261","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-10-261","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2136172853.pdf","grobid_xml":"https://content.openalex.org/works/W2136172853.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1577941315","https://openalex.org/W1965563731","https://openalex.org/W2059206901","https://openalex.org/W2065691575","https://openalex.org/W2087244229","https://openalex.org/W2087484885","https://openalex.org/W2090604846","https://openalex.org/W2126718294","https://openalex.org/W2141088880","https://openalex.org/W2167805526","https://openalex.org/W2402189831","https://openalex.org/W4300190830"],"related_works":["https://openalex.org/W2076845124","https://openalex.org/W3099554367","https://openalex.org/W2291338467","https://openalex.org/W2262248604","https://openalex.org/W2564551024","https://openalex.org/W2483883060","https://openalex.org/W1977950832","https://openalex.org/W2187184338","https://openalex.org/W187374258","https://openalex.org/W4211190891"],"abstract_inverted_index":{"Our":[0],"results":[1],"fill":[2],"a":[3],"need":[4],"in":[5],"power":[6],"calculations":[7],"for":[8],"QTL":[9],"mapping":[10],"studies.":[11],"Furthermore,":[12],"failure":[13],"to":[14],"appropriately":[15],"model":[16],"haploid":[17],"loci":[18],"may":[19],"cause":[20],"underestimation":[21],"of":[22],"power.":[23]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}