{"id":"https://openalex.org/W4401425126","doi":"https://doi.org/10.1177/14604582241270778","title":"Machine learning model for osteoporosis diagnosis based on bone turnover markers","display_name":"Machine learning model for osteoporosis diagnosis based on bone turnover markers","publication_year":2024,"publication_date":"2024-07-01","ids":{"openalex":"https://openalex.org/W4401425126","doi":"https://doi.org/10.1177/14604582241270778","pmid":"https://pubmed.ncbi.nlm.nih.gov/39115269"},"language":"en","primary_location":{"id":"doi:10.1177/14604582241270778","is_oa":true,"landing_page_url":"https://doi.org/10.1177/14604582241270778","pdf_url":null,"source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1177/14604582241270778","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039413983","display_name":"Seung Min Baik","orcid":"https://orcid.org/0000-0003-1051-6775"},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]},{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seung Min Baik","raw_affiliation_strings":["Department of Surgery, Korea University College of Medicine, Seoul, Korea","Division of Critical Care Medicine, Department of Surgery, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0003-1051-6775","affiliations":[{"raw_affiliation_string":"Department of Surgery, Korea University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"Division of Critical Care Medicine, Department of Surgery, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I138925566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000352521","display_name":"Hi Jeong Kwon","orcid":"https://orcid.org/0000-0002-1108-5463"},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hi Jeong Kwon","raw_affiliation_strings":["Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053925132","display_name":"Yeongsic Kim","orcid":"https://orcid.org/0000-0001-5815-5185"},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeongsic Kim","raw_affiliation_strings":["Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101482854","display_name":"Jehoon Lee","orcid":"https://orcid.org/0000-0002-1401-1478"},"institutions":[{"id":"https://openalex.org/I4210160144","display_name":"The Catholic University of Korea Seoul St. Mary's Hospital","ror":"https://ror.org/056cn0e37","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210160144","https://openalex.org/I4405260414","https://openalex.org/I87111246"]},{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jehoon Lee","raw_affiliation_strings":["Department of Laboratory Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea","institution_ids":["https://openalex.org/I4210160144","https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009522689","display_name":"Young Hoon Park","orcid":"https://orcid.org/0000-0003-4516-7990"},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Hoon Park","raw_affiliation_strings":["Division of Hematology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I138925566"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101415571","display_name":"Dong Jin Park","orcid":"https://orcid.org/0000-0002-2412-5292"},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Dong Jin Park","raw_affiliation_strings":["Department of Laboratory Medicine, Eunpyeong St Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"],"raw_orcid":"https://orcid.org/0000-0002-2412-5292","affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Eunpyeong St Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea","institution_ids":["https://openalex.org/I87111246"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101415571"],"corresponding_institution_ids":["https://openalex.org/I87111246"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":4.0369,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.94286965,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"30","issue":"3","first_page":"14604582241270778","last_page":"14604582241270778"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11363","display_name":"Dental Radiography and Imaging","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoporosis","display_name":"Osteoporosis","score":0.8450606465339661},{"id":"https://openalex.org/keywords/gradient-boosting","display_name":"Gradient boosting","score":0.7706791162490845},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6971256732940674},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6636291146278381},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.6604795455932617},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.6407673358917236},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6000226736068726},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.49825525283813477},{"id":"https://openalex.org/keywords/boosting","display_name":"Boosting (machine learning)","score":0.4613267481327057},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3380933403968811},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.30207210779190063}],"concepts":[{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8450606465339661},{"id":"https://openalex.org/C70153297","wikidata":"https://www.wikidata.org/wiki/Q5591907","display_name":"Gradient boosting","level":3,"score":0.7706791162490845},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6971256732940674},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6636291146278381},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.6604795455932617},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.6407673358917236},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6000226736068726},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.49825525283813477},{"id":"https://openalex.org/C46686674","wikidata":"https://www.wikidata.org/wiki/Q466303","display_name":"Boosting (machine learning)","level":2,"score":0.4613267481327057},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3380933403968811},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30207210779190063}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1177/14604582241270778","is_oa":true,"landing_page_url":"https://doi.org/10.1177/14604582241270778","pdf_url":null,"source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},{"id":"pmid:39115269","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39115269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health informatics journal","raw_type":null},{"id":"pmh:oai:doaj.org/article:8151388df2764e4f8081a2242ba82227","is_oa":true,"landing_page_url":"https://doaj.org/article/8151388df2764e4f8081a2242ba82227","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Health Informatics Journal, Vol 30 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/14604582241270778","is_oa":true,"landing_page_url":"https://doi.org/10.1177/14604582241270778","pdf_url":null,"source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","score":0.47999998927116394,"id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G7831275123","display_name":null,"funder_award_id":"KAHP-2019-03","funder_id":"https://openalex.org/F6110763375","funder_display_name":"Korea Association of Health Promotion"}],"funders":[{"id":"https://openalex.org/F6110763375","display_name":"Korea Association of Health Promotion","ror":"https://ror.org/01eqqdz04"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1832304720","https://openalex.org/W1967468486","https://openalex.org/W2005229665","https://openalex.org/W2009508470","https://openalex.org/W2027852937","https://openalex.org/W2036125852","https://openalex.org/W2053125236","https://openalex.org/W2053389701","https://openalex.org/W2107789045","https://openalex.org/W2129704145","https://openalex.org/W2177870565","https://openalex.org/W2340782621","https://openalex.org/W2342603028","https://openalex.org/W2560982011","https://openalex.org/W2733907025","https://openalex.org/W2766894798","https://openalex.org/W2782286529","https://openalex.org/W2807378036","https://openalex.org/W2888353590","https://openalex.org/W2888981672","https://openalex.org/W2892221324","https://openalex.org/W2946722168","https://openalex.org/W2954992390","https://openalex.org/W2971267910","https://openalex.org/W2982488225","https://openalex.org/W2990091959","https://openalex.org/W3142654793","https://openalex.org/W3170495878","https://openalex.org/W3185494014","https://openalex.org/W3212457727","https://openalex.org/W3212925550","https://openalex.org/W4235699389","https://openalex.org/W4297133941","https://openalex.org/W4297134219","https://openalex.org/W4297134224","https://openalex.org/W4376453587"],"related_works":["https://openalex.org/W2967733078","https://openalex.org/W3204430031","https://openalex.org/W3137904399","https://openalex.org/W4310492845","https://openalex.org/W4386690025","https://openalex.org/W2885778889","https://openalex.org/W4310224730","https://openalex.org/W2766514146","https://openalex.org/W4289703016","https://openalex.org/W2885516856"],"abstract_inverted_index":{"To":[0],"assess":[1],"the":[2,74,77,91,108,149,167],"diagnostic":[3],"utility":[4],"of":[5,94,121,125,130,151,170],"bone":[6],"turnover":[7],"markers":[8],"(BTMs)":[9],"and":[10,36,61,84,115,127,136,157,184],"demographic":[11,158],"variables":[12,159],"for":[13,160,181],"identifying":[14],"individuals":[15],"with":[16,34,134],"osteoporosis.":[17,40,163],"A":[18],"cross-sectional":[19],"study":[20,147],"involving":[21],"280":[22],"participants":[23],"was":[24,101],"conducted.":[25],"Serum":[26],"BTM":[27],"values":[28],"were":[29,64,138],"obtained":[30],"from":[31,103],"88":[32],"patients":[33],"osteoporosis":[35,68,144,175],"192":[37],"controls":[38],"without":[39],"Six":[41],"machine":[42,53,152],"learning":[43,153],"models,":[44],"including":[45],"extreme":[46],"gradient":[47,51],"boosting":[48,52],"(XGBoost),":[49],"light":[50],"(LGBM),":[54],"CatBoost,":[55],"random":[56],"forest,":[57],"support":[58],"vector":[59],"machine,":[60],"k-nearest":[62],"neighbors,":[63],"employed":[65],"to":[66,105,140,143],"evaluate":[67],"diagnosis.":[69,145],"The":[70,164],"performance":[71],"measures":[72],"included":[73],"area":[75],"under":[76],"receiver":[78],"operating":[79],"characteristic":[80],"curve":[81],"(AUROC),":[82],"F1-score,":[83],"accuracy.":[85],"After":[86],"AUROC":[87,93,120],"optimization,":[88,98],"LGBM":[89],"exhibited":[90],"highest":[92],"0.706.":[95],"Post":[96],"F1-score":[97,100,124],"LGBM's":[99],"improved":[102],"0.50":[104],"0.65.":[106],"Combining":[107],"top":[109],"three":[110],"optimized":[111],"models":[112,154],"(LGBM,":[113],"XGBoost,":[114],"CatBoost)":[116],"resulted":[117],"in":[118,174],"an":[119,123,128],"0.706,":[122],"0.65,":[126],"accuracy":[129],"0.73.":[131],"BTMs,":[132],"along":[133],"age":[135],"sex,":[137],"found":[139],"contribute":[141],"significantly":[142],"This":[146],"demonstrates":[148],"potential":[150],"utilizing":[155],"BTMs":[156],"diagnosing":[161],"preexisting":[162],"findings":[165],"highlight":[166],"clinical":[168,172],"relevance":[169],"accessible":[171],"data":[173],"assessment,":[176],"providing":[177],"a":[178],"promising":[179],"tool":[180],"early":[182],"diagnosis":[183],"management.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}