{"id":"https://openalex.org/W2949554208","doi":"https://doi.org/10.1177/1460458219850682","title":"Prediction and prevention of hypoglycaemic events in type-1 diabetic patients using machine learning","display_name":"Prediction and prevention of hypoglycaemic events in type-1 diabetic patients using machine learning","publication_year":2019,"publication_date":"2019-06-13","ids":{"openalex":"https://openalex.org/W2949554208","doi":"https://doi.org/10.1177/1460458219850682","mag":"2949554208","pmid":"https://pubmed.ncbi.nlm.nih.gov/31195880"},"language":"en","primary_location":{"id":"doi:10.1177/1460458219850682","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1460458219850682","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1460458219850682","source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/1460458219850682","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069860044","display_name":"Josep Veh\u0131\u0301","orcid":"https://orcid.org/0000-0001-6884-9789"},"institutions":[{"id":"https://openalex.org/I251424209","display_name":"Universitat de Girona","ror":"https://ror.org/01xdxns91","country_code":"ES","type":"education","lineage":["https://openalex.org/I251424209"]},{"id":"https://openalex.org/I4210092133","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Diabetes y Enfermedades Metab\u00f3licas Asociadas","ror":"https://ror.org/00dwgct76","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210092133","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Josep Veh\u00ed","raw_affiliation_strings":["Universitat de Girona, Spain; Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Spain"],"raw_orcid":"https://orcid.org/0000-0001-6884-9789","affiliations":[{"raw_affiliation_string":"Universitat de Girona, Spain; Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Spain","institution_ids":["https://openalex.org/I4210092133","https://openalex.org/I251424209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051063958","display_name":"Iv\u00e1n Contreras","orcid":"https://orcid.org/0000-0001-6896-818X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iv\u00e1n Contreras","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111635342","display_name":"Silvia Oviedo","orcid":null},"institutions":[{"id":"https://openalex.org/I251424209","display_name":"Universitat de Girona","ror":"https://ror.org/01xdxns91","country_code":"ES","type":"education","lineage":["https://openalex.org/I251424209"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Silvia Oviedo","raw_affiliation_strings":["Universitat de Girona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitat de Girona, Spain","institution_ids":["https://openalex.org/I251424209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005012144","display_name":"Lyvia Biagi","orcid":"https://orcid.org/0000-0003-3356-8375"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lyvia Biagi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3356-8375","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012527307","display_name":"Arthur Bertachi","orcid":"https://orcid.org/0000-0001-7336-6941"},"institutions":[{"id":"https://openalex.org/I1283613182","display_name":"Universidade Tecnol\u00f3gica Federal do Paran\u00e1","ror":"https://ror.org/002v2kq79","country_code":"BR","type":"education","lineage":["https://openalex.org/I1283613182"]},{"id":"https://openalex.org/I251424209","display_name":"Universitat de Girona","ror":"https://ror.org/01xdxns91","country_code":"ES","type":"education","lineage":["https://openalex.org/I251424209"]}],"countries":["BR","ES"],"is_corresponding":false,"raw_author_name":"Arthur Bertachi","raw_affiliation_strings":["Universitat de Girona, Spain; Federal University of Technology \u2013 Paran\u00e1 (UTFPR), Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitat de Girona, Spain; Federal University of Technology \u2013 Paran\u00e1 (UTFPR), Brazil","institution_ids":["https://openalex.org/I1283613182","https://openalex.org/I251424209"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5069860044"],"corresponding_institution_ids":["https://openalex.org/I251424209","https://openalex.org/I4210092133"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":null,"fwci":5.8784,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.97077666,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"26","issue":"1","first_page":"703","last_page":"718"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.988099992275238,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.702619731426239},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5986449122428894},{"id":"https://openalex.org/keywords/postprandial","display_name":"Postprandial","score":0.5875874757766724},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"Diabetes mellitus","score":0.5544259548187256},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"Type 2 diabetes","score":0.5491403341293335},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4992349147796631},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.4650512933731079},{"id":"https://openalex.org/keywords/adverse-effect","display_name":"Adverse effect","score":0.4476081430912018},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42704808712005615},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2667376399040222},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.10426720976829529}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.702619731426239},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5986449122428894},{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.5875874757766724},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5544259548187256},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5491403341293335},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4992349147796631},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4650512933731079},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4476081430912018},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42704808712005615},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2667376399040222},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.10426720976829529}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007003","descriptor_name":"Hypoglycemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1177/1460458219850682","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1460458219850682","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1460458219850682","source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},{"id":"pmid:31195880","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31195880","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health informatics journal","raw_type":null},{"id":"pmh:oai:doaj.org/article:38f1bf351ed5457d880e053176d33fd0","is_oa":true,"landing_page_url":"https://doaj.org/article/38f1bf351ed5457d880e053176d33fd0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Health Informatics Journal, Vol 26 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/1460458219850682","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1460458219850682","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1460458219850682","source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5199999809265137}],"awards":[{"id":"https://openalex.org/G216720077","display_name":null,"funder_award_id":"207688/2014-1","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"},{"id":"https://openalex.org/G3001070732","display_name":null,"funder_award_id":"DPI2016-78831-C2-2-R","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G8125165381","display_name":null,"funder_award_id":"202050/2015-7","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"},{"id":"https://openalex.org/G8864903239","display_name":null,"funder_award_id":"ES-2014-068289","funder_id":"https://openalex.org/F4320321764","funder_display_name":"Ministerio de Educaci\u00f3n, Cultura y Deporte"}],"funders":[{"id":"https://openalex.org/F4320321764","display_name":"Ministerio de Educaci\u00f3n, Cultura y Deporte","ror":"https://ror.org/03nc27g21"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":"https://ror.org/034900433"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2949554208.pdf"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W944776124","https://openalex.org/W1560724230","https://openalex.org/W1569512666","https://openalex.org/W1752045965","https://openalex.org/W1964693647","https://openalex.org/W1964947170","https://openalex.org/W1978849955","https://openalex.org/W1980337932","https://openalex.org/W1986495510","https://openalex.org/W1989964158","https://openalex.org/W2035857772","https://openalex.org/W2043209605","https://openalex.org/W2082984393","https://openalex.org/W2109553965","https://openalex.org/W2118323629","https://openalex.org/W2118978333","https://openalex.org/W2124282046","https://openalex.org/W2128859735","https://openalex.org/W2129995532","https://openalex.org/W2131587651","https://openalex.org/W2163532367","https://openalex.org/W2171613573","https://openalex.org/W2190748907","https://openalex.org/W2302984431","https://openalex.org/W2388765709","https://openalex.org/W2463067599","https://openalex.org/W2516554535","https://openalex.org/W2523526638","https://openalex.org/W2587843318","https://openalex.org/W2596063051","https://openalex.org/W2610421233","https://openalex.org/W2618019966","https://openalex.org/W2742286538","https://openalex.org/W2767819117","https://openalex.org/W2769264260","https://openalex.org/W2769674107","https://openalex.org/W2803397755","https://openalex.org/W2804354698","https://openalex.org/W2882545419","https://openalex.org/W2888821611","https://openalex.org/W2889087356","https://openalex.org/W2899007023","https://openalex.org/W3144619878","https://openalex.org/W4229944666","https://openalex.org/W4244027109","https://openalex.org/W4252271922","https://openalex.org/W4388297464"],"related_works":["https://openalex.org/W2940950084","https://openalex.org/W4291284026","https://openalex.org/W2379081288","https://openalex.org/W2010624657","https://openalex.org/W2138603750","https://openalex.org/W2129387753","https://openalex.org/W2084692954","https://openalex.org/W1996268130","https://openalex.org/W2394474110","https://openalex.org/W1997477595"],"abstract_inverted_index":{"Tight":[0],"blood":[1,135],"glucose":[2,45,136],"control":[3,43],"reduces":[4,186],"the":[5,25,54,62,67,75,110,119,130,171,179,187],"risk":[6,55],"of":[7,44,56,69,77,79,112,121,134,170,173,178,189,191],"microvascular":[8],"and":[9,29,158,175,195],"macrovascular":[10],"complications":[11],"in":[12,47,66,123,201],"patients":[13,48,80,197],"with":[14,198],"type":[15,70],"1":[16,71],"diabetes.":[17],"However,":[18],"this":[19,83],"is":[20,53,61],"very":[21],"difficult":[22],"due":[23],"to":[24,40,98,117,142,153,162],"large":[26],"intra-individual":[27],"variability":[28],"other":[30],"factors":[31],"that":[32],"affect":[33],"glycaemic":[34,105],"control.":[35],"The":[36,167,182],"main":[37,63],"limiting":[38],"factor":[39],"achieve":[41],"strict":[42],"levels":[46],"on":[49,89],"intensive":[50],"insulin":[51],"therapy":[52],"severe":[57],"hypoglycaemia.":[58],"Therefore,":[59],"hypoglycaemia":[60],"safety":[64,101,122,194],"problem":[65,120],"treatment":[68],"diabetes,":[72],"negatively":[73],"affecting":[74],"quality":[76],"life":[78],"suffering":[81],"from":[82],"disease.":[84],"Decision":[85],"support":[86,139],"tools":[87],"based":[88],"machine":[90,114],"learning":[91,115],"methods":[92],"have":[93],"become":[94],"a":[95],"viable":[96],"way":[97],"enhance":[99],"patient":[100],"by":[102],"anticipating":[103],"adverse":[104],"events.":[106],"This":[107],"study":[108],"proposes":[109],"application":[111],"four":[113],"algorithms":[116],"tackle":[118],"diabetes":[124,164],"management:":[125],"(1)":[126],"grammatical":[127],"evolution":[128],"for":[129],"mid-term":[131],"continuous":[132],"prediction":[133,174],"levels,":[137],"(2)":[138],"vector":[140],"machines":[141],"predict":[143,154],"hypoglycaemic":[144,155],"events":[145],"during":[146],"postprandial":[147],"periods,":[148],"(3)":[149],"artificial":[150],"neural":[151],"networks":[152],"episodes":[156,190],"overnight,":[157],"(4)":[159],"data":[160],"mining":[161],"profile":[163],"management":[165],"scenarios.":[166],"proposal":[168],"consists":[169],"combination":[172],"classification":[176],"capabilities":[177],"implemented":[180],"approaches.":[181],"resulting":[183],"system":[184],"significantly":[185],"number":[188],"hypoglycaemia,":[192],"improving":[193],"providing":[196],"greater":[199],"confidence":[200],"decision-making.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":9}],"updated_date":"2026-05-22T06:13:13.366637","created_date":"2025-10-10T00:00:00"}