{"id":"https://openalex.org/W2791213314","doi":"https://doi.org/10.1177/1460458217749883","title":"Adverse Event extraction from Structured Product Labels using the Event-based Text-mining of Health Electronic Records (ETHER) system","display_name":"Adverse Event extraction from Structured Product Labels using the Event-based Text-mining of Health Electronic Records (ETHER) system","publication_year":2018,"publication_date":"2018-01-23","ids":{"openalex":"https://openalex.org/W2791213314","doi":"https://doi.org/10.1177/1460458217749883","mag":"2791213314","pmid":"https://pubmed.ncbi.nlm.nih.gov/29359620"},"language":"en","primary_location":{"id":"doi:10.1177/1460458217749883","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1460458217749883","pdf_url":null,"source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021662681","display_name":"Abhishek Pandey","orcid":"https://orcid.org/0000-0003-0618-2362"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Abhishek Pandey","raw_affiliation_strings":["United States Food and Drug Administration"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"United States Food and Drug Administration","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026956396","display_name":"Kory Kreimeyer","orcid":"https://orcid.org/0000-0002-5434-1420"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kory Kreimeyer","raw_affiliation_strings":["United States Food and Drug Administration"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"United States Food and Drug Administration","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054541849","display_name":"Matthew Foster","orcid":"https://orcid.org/0000-0002-1865-6169"},"institutions":[{"id":"https://openalex.org/I1318287680","display_name":"Center for Biologics Evaluation and Research","ror":"https://ror.org/02nr3fr97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1318287680","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Foster","raw_affiliation_strings":["Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, US Food and Drug Administration, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, US Food and Drug Administration, USA","institution_ids":["https://openalex.org/I1318287680","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076602978","display_name":"Oanh Dang","orcid":"https://orcid.org/0009-0007-9505-945X"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oanh Dang","raw_affiliation_strings":["Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, USA","institution_ids":["https://openalex.org/I1333606569","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034731188","display_name":"Thomas Ly","orcid":null},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1333606569","display_name":"Center for Drug Evaluation and Research","ror":"https://ror.org/00yf3tm42","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1333606569"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Ly","raw_affiliation_strings":["Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, USA","institution_ids":["https://openalex.org/I1333606569","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102710129","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0001-8980-2680"},"institutions":[{"id":"https://openalex.org/I4210104289","display_name":"Engility (United States)","ror":"https://ror.org/01h2d3422","country_code":"US","type":"company","lineage":["https://openalex.org/I4210104289"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Engility Corporation, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engility Corporation, USA","institution_ids":["https://openalex.org/I4210104289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087332112","display_name":"Richard A. Forshee","orcid":"https://orcid.org/0000-0002-5805-2837"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Forshee","raw_affiliation_strings":["United States Food and Drug Administration"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"United States Food and Drug Administration","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070026501","display_name":"Taxiarchis Botsis","orcid":"https://orcid.org/0000-0001-7848-2570"},"institutions":[{"id":"https://openalex.org/I1318287680","display_name":"Center for Biologics Evaluation and Research","ror":"https://ror.org/02nr3fr97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1318287680","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taxiarchis Botsis","raw_affiliation_strings":["Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, US Food and Drug Administration, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, US Food and Drug Administration, USA","institution_ids":["https://openalex.org/I1318287680","https://openalex.org/I1320320070"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5021662681"],"corresponding_institution_ids":["https://openalex.org/I1320320070"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":null,"fwci":0.8349,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.71774793,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"25","issue":"4","first_page":"1232","last_page":"1243"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11719","display_name":"Data Quality and Management","score":0.9861000180244446,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13083","display_name":"Advanced Text Analysis Techniques","score":0.9638000130653381,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/event","display_name":"Event (particle physics)","score":0.6232362389564514},{"id":"https://openalex.org/keywords/health-records","display_name":"Health records","score":0.5816110372543335},{"id":"https://openalex.org/keywords/adverse-event-reporting-system","display_name":"Adverse Event Reporting System","score":0.5711231827735901},{"id":"https://openalex.org/keywords/product","display_name":"Product (mathematics)","score":0.5160036087036133},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5081560611724854},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.43045735359191895},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3823571801185608},{"id":"https://openalex.org/keywords/adverse-effect","display_name":"Adverse effect","score":0.3598383069038391},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28250443935394287},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.19735366106033325},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.10497725009918213}],"concepts":[{"id":"https://openalex.org/C2779662365","wikidata":"https://www.wikidata.org/wiki/Q5416694","display_name":"Event (particle physics)","level":2,"score":0.6232362389564514},{"id":"https://openalex.org/C3019952477","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Health records","level":3,"score":0.5816110372543335},{"id":"https://openalex.org/C2777105317","wikidata":"https://www.wikidata.org/wiki/Q4686710","display_name":"Adverse Event Reporting System","level":3,"score":0.5711231827735901},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.5160036087036133},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5081560611724854},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.43045735359191895},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3823571801185608},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.3598383069038391},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28250443935394287},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.19735366106033325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10497725009918213},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004348","descriptor_name":"Drug Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004348","descriptor_name":"Drug Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004348","descriptor_name":"Drug Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/1460458217749883","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1460458217749883","pdf_url":null,"source":{"id":"https://openalex.org/S201800618","display_name":"Health Informatics Journal","issn_l":"1460-4582","issn":["1460-4582","1741-2811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Informatics Journal","raw_type":"journal-article"},{"id":"pmid:29359620","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29359620","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health informatics journal","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332382","display_name":"Oak Ridge Institute for Science and Education","ror":"https://ror.org/0526p1y61"},{"id":"https://openalex.org/F4320335265","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W2026956787","https://openalex.org/W2049946556","https://openalex.org/W2065721283","https://openalex.org/W2102937034","https://openalex.org/W2104400119","https://openalex.org/W2117953109","https://openalex.org/W2122402213","https://openalex.org/W2124359492","https://openalex.org/W2133499793","https://openalex.org/W2139865360","https://openalex.org/W2145578524","https://openalex.org/W2476207573"],"related_works":["https://openalex.org/W1669499790","https://openalex.org/W4282838629","https://openalex.org/W1967736925","https://openalex.org/W4281861147","https://openalex.org/W4391172823","https://openalex.org/W4388132138","https://openalex.org/W2342267228","https://openalex.org/W3011938841","https://openalex.org/W2918034594","https://openalex.org/W4280493563"],"abstract_inverted_index":{"Structured":[0,58,69,152],"Product":[1,59,70,153],"Labels":[2,71,154],"follow":[3],"an":[4],"XML-based":[5],"document":[6],"markup":[7],"standard":[8],"approved":[9],"by":[10,18],"the":[11,19,44,63,73,113],"Health":[12,77,119,140],"Level":[13],"Seven":[14],"organization":[15,35],"and":[16,22,49,81,87,125,130,146],"adopted":[17],"US":[20],"Food":[21],"Drug":[23],"Administration":[24],"as":[25],"a":[26,53,123],"mechanism":[27],"for":[28,95,109],"exchanging":[29],"medical":[30],"products":[31],"information.":[32],"Their":[33],"current":[34],"makes":[36],"their":[37],"secondary":[38],"use":[39],"rather":[40],"challenging.":[41],"We":[42,61],"used":[43],"Side":[45],"Effect":[46],"Resource":[47],"database":[48],"DailyMed":[50],"to":[51,85,92,144],"generate":[52],"comparison":[54],"dataset":[55],"of":[56,67,76,103,118,127,139],"1159":[57],"Labels.":[60],"processed":[62],"Adverse":[64,89,148],"Reaction":[65],"section":[66],"these":[68],"with":[72],"Event-based":[74,116,137],"Text-mining":[75,117,138],"Electronic":[78,120,141],"Records":[79,121],"system":[80],"evaluated":[82],"its":[83],"ability":[84,143],"extract":[86,145],"encode":[88,147],"Event":[90,149],"terms":[91,150],"Medical":[93],"Dictionary":[94],"Regulatory":[96],"Activities":[97],"Preferred":[98],"Terms.":[99],"A":[100],"small":[101],"sample":[102],"100":[104,114],"labels":[105],"was":[106],"then":[107],"selected":[108],"further":[110],"analysis.":[111],"Of":[112],"labels,":[115],"achieved":[122],"precision":[124],"recall":[126],"81":[128],"percent":[129],"92":[131],"percent,":[132],"respectively.":[133],"This":[134],"study":[135],"demonstrated":[136],"Record's":[142],"from":[151],"which":[155],"may":[156],"potentially":[157],"support":[158],"multiple":[159],"pharmacoepidemiological":[160],"tasks.":[161]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-29T09:21:14.243279","created_date":"2025-10-10T00:00:00"}