{"id":"https://openalex.org/W4407614423","doi":"https://doi.org/10.1177/1088467x241313324","title":"Multi-path neural network based on mp-MRI for predicting muscle-invasive bladder cancer","display_name":"Multi-path neural network based on mp-MRI for predicting muscle-invasive bladder cancer","publication_year":2025,"publication_date":"2025-02-16","ids":{"openalex":"https://openalex.org/W4407614423","doi":"https://doi.org/10.1177/1088467x241313324"},"language":"en","primary_location":{"id":"doi:10.1177/1088467x241313324","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1088467x241313324","pdf_url":null,"source":{"id":"https://openalex.org/S2498839158","display_name":"Intelligent Data Analysis","issn_l":"1088-467X","issn":["1088-467X","1571-4128"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Intelligent Data Analysis: An International Journal","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101546629","display_name":"Jie Yu","orcid":"https://orcid.org/0000-0002-8108-4829"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Yu","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070338555","display_name":"Lingkai Cai","orcid":"https://orcid.org/0000-0002-1056-9116"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingkai Cai","raw_affiliation_strings":["The First Affiliated Hospital with Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital with Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025758432","display_name":"Chunxiao Chen","orcid":"https://orcid.org/0000-0002-9440-9426"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chunxiao Chen","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-9440-9426","affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101210619","display_name":"Xue Fu","orcid":null},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xue Fu","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0009-0007-1800-122X","affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010547629","display_name":"Yueyue Xiao","orcid":"https://orcid.org/0009-0006-9606-2282"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueyue Xiao","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456480","display_name":"Liang Wang","orcid":"https://orcid.org/0000-0001-8115-1094"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Wang","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017147831","display_name":"Qinghua Zeng","orcid":"https://orcid.org/0000-0002-0715-1325"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinghua Zeng","raw_affiliation_strings":["School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027958504","display_name":"Xueying Sun","orcid":"https://orcid.org/0000-0002-5748-6625"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueying Sun","raw_affiliation_strings":["The First Affiliated Hospital with Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital with Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069929902","display_name":"Gongcheng Wang","orcid":"https://orcid.org/0000-0001-6484-6409"},"institutions":[{"id":"https://openalex.org/I4210097726","display_name":"Huaian First People\u2019s Hospital","ror":"https://ror.org/00xpfw690","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097726"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gongcheng Wang","raw_affiliation_strings":["The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4210097726","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036462549","display_name":"Qiang Shao","orcid":null},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Shao","raw_affiliation_strings":["The Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083812342","display_name":"Xiao Yang","orcid":"https://orcid.org/0000-0002-5429-9162"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Yang","raw_affiliation_strings":["The First Affiliated Hospital with Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital with Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008113490","display_name":"Qiang L\u00fc","orcid":"https://orcid.org/0000-0003-3589-2507"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiang Lu","raw_affiliation_strings":["The First Affiliated Hospital with Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital with Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5008113490","https://openalex.org/A5025758432"],"corresponding_institution_ids":["https://openalex.org/I83519826","https://openalex.org/I9842412"],"apc_list":null,"apc_paid":null,"fwci":1.1418,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.72348633,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"29","issue":"6","first_page":"1568","last_page":"1581"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"Bladder cancer","score":0.8457217216491699},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5713111758232117},{"id":"https://openalex.org/keywords/path","display_name":"Path (computing)","score":0.4997870922088623},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.467575341463089},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3908997178077698},{"id":"https://openalex.org/keywords/urology","display_name":"Urology","score":0.36053234338760376},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3504960536956787},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3331855535507202},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2637336254119873},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.23983338475227356},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.0857478678226471}],"concepts":[{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.8457217216491699},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5713111758232117},{"id":"https://openalex.org/C2777735758","wikidata":"https://www.wikidata.org/wiki/Q817765","display_name":"Path (computing)","level":2,"score":0.4997870922088623},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.467575341463089},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3908997178077698},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.36053234338760376},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3504960536956787},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3331855535507202},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2637336254119873},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23983338475227356},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0857478678226471}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1177/1088467x241313324","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1088467x241313324","pdf_url":null,"source":{"id":"https://openalex.org/S2498839158","display_name":"Intelligent Data Analysis","issn_l":"1088-467X","issn":["1088-467X","1571-4128"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Intelligent Data Analysis: An International Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4185672457","display_name":"\u57fa\u4e8e\u9759-\u52a8\u6001\u8026\u5408\u6a21\u578b\u7684\u751f\u7269\u53d1\u5149\u5c42\u6790\u6210\u50cf\u7684\u9002\u5b9a\u6027\u4e0e\u6b63\u5219\u5316\u65b9\u6cd5\u7814\u7a76","funder_award_id":"12071215","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W2183341477","https://openalex.org/W2194775991","https://openalex.org/W2533800772","https://openalex.org/W2734892359","https://openalex.org/W2773701834","https://openalex.org/W2794022343","https://openalex.org/W2800613296","https://openalex.org/W2884561390","https://openalex.org/W2886825231","https://openalex.org/W2894069389","https://openalex.org/W2913340405","https://openalex.org/W2963125010","https://openalex.org/W2990761728","https://openalex.org/W2999417355","https://openalex.org/W3009535750","https://openalex.org/W3012438829","https://openalex.org/W3013617185","https://openalex.org/W3017359123","https://openalex.org/W3023288864","https://openalex.org/W3033618003","https://openalex.org/W3085068588","https://openalex.org/W3102493364","https://openalex.org/W3123241743","https://openalex.org/W3126474728","https://openalex.org/W3134553072","https://openalex.org/W3136816266","https://openalex.org/W3166877082","https://openalex.org/W3171537998","https://openalex.org/W3176494267","https://openalex.org/W3198719997","https://openalex.org/W4200112506","https://openalex.org/W4213083425","https://openalex.org/W4220746509","https://openalex.org/W4224280177","https://openalex.org/W4307235792","https://openalex.org/W4310081561","https://openalex.org/W4323276171","https://openalex.org/W4380927470"],"related_works":["https://openalex.org/W2898558914","https://openalex.org/W4237262135","https://openalex.org/W3127976301","https://openalex.org/W2981899172","https://openalex.org/W1522132782","https://openalex.org/W2982282360","https://openalex.org/W2160411124","https://openalex.org/W2944005863","https://openalex.org/W3195745733","https://openalex.org/W2943930186"],"abstract_inverted_index":{"Purpose":[0],"To":[1],"assist":[2],"doctors":[3],"in":[4,96,224,234,246],"clinical":[5],"diagnosis,":[6],"we":[7],"propose":[8],"a":[9,93,150],"multipath":[10],"deep":[11],"learning":[12],"(MP-DL)":[13],"model":[14,40,87,119,183,217],"to":[15,106],"distinguish":[16],"between":[17],"muscle-invasive":[18],"bladder":[19,24],"cancer":[20,25],"(MIBC)":[21],"and":[22,33,48,68,99,110,117,125,132,144,160,172,191,199,213,230,254],"non-muscle-invasive":[23],"(NMIBC)":[26],"using":[27],"multiparametric":[28],"magnetic":[29],"resonance":[30],"imaging":[31,46,51],"(mp-MRI)":[32],"synthesized":[34,158,242],"samples.":[35],"Methods":[36],"The":[37,136,216,238],"proposed":[38],"MP-DL":[39,239],"integrates":[41],"T2-weighted":[42],"image":[43],"(T2WI),":[44],"diffusion-weighted":[45],"(DWI),":[47],"dynamic":[49],"contrast-enhanced":[50],"(DCE)":[52],"branches,":[53],"combining":[54],"high-level":[55],"features":[56],"from":[57,72],"these":[58],"sequences.":[59],"Multichannel":[60],"inputs,":[61],"including":[62],"the":[63,73,77,80,86,97,114,129,179,182,203,206],"original":[64],"image,":[65],"segmented":[66],"bladder,":[67],"region":[69],"of":[70,139,153,164,169,175,194,221],"interest":[71],"T2WI":[74],"branch,":[75],"enhance":[76],"focus":[78],"on":[79],"tumor":[81],"region.":[82],"InceptionV3":[83],"served":[84],"as":[85],"backbone":[88],"for":[89],"feature":[90],"extraction":[91],"with":[92],"multitask":[94],"framework":[95],"DWI":[98,109,159],"DCE":[100,111,161],"branches.":[101],"Synthesized":[102],"samples":[103],"were":[104,208],"generated":[105],"supplement":[107],"missing":[108],"sequences,":[112],"enlarging":[113],"sample":[115],"size":[116],"boosting":[118],"performance.":[120],"Evaluation":[121],"through":[122],"five-fold":[123],"cross-validation":[124],"internal-external":[126],"testing":[127,168,174,226],"demonstrated":[128],"model's":[130],"robustness":[131],"generalization":[133],"capabilities.":[134],"Results":[135],"dataset":[137],"consisted":[138],"401":[140],"cases":[141,155],"(287":[142],"NMIBC":[143],"114":[145],"MIBC":[146,248],"cases),":[147],"which":[148],"included":[149],"training":[151],"set":[152],"313":[154],"(containing":[156],"partly":[157],"samples),":[162],"validation":[163],"26":[165],"cases,":[166,171],"internal":[167,180,225],"34":[170],"external":[173,204,235],"28":[176],"cases.":[177],"In":[178,202],"testing,":[181,205],"achieved":[184],"area":[185],"under":[186],"curve,":[187],"accuracy,":[188],"sensitivity,":[189],"specificity,":[190],"F1":[192],"scores":[193],"0.914,":[195],"0.835,":[196],"0.880,":[197],"0.817,":[198],"0.761,":[200],"respectively.":[201,215],"results":[207],"0.821,":[209],"0.814,":[210],"0.730,":[211],"0.845,":[212],"0.619,":[214],"performance":[218],"surpasses":[219],"that":[220],"medical":[222],"professionals":[223],"while":[227],"outperforming":[228],"urologists":[229,253],"approaching":[231],"senior":[232],"radiologists":[233],"testing.":[236],"Conclusions":[237],"model,":[240],"incorporating":[241],"samples,":[243],"shows":[244],"promise":[245],"preoperative":[247],"prediction,":[249],"potentially":[250],"aiding":[251],"primary":[252],"radiologists.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}