{"id":"https://openalex.org/W2051900899","doi":"https://doi.org/10.1177/0278364905059108","title":"Probik: Protein Backbone Motion by Inverse Kinematics","display_name":"Probik: Protein Backbone Motion by Inverse Kinematics","publication_year":2005,"publication_date":"2005-11-01","ids":{"openalex":"https://openalex.org/W2051900899","doi":"https://doi.org/10.1177/0278364905059108","mag":"2051900899"},"language":"en","primary_location":{"id":"doi:10.1177/0278364905059108","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0278364905059108","pdf_url":null,"source":{"id":"https://openalex.org/S73484101","display_name":"The International Journal of Robotics Research","issn_l":"0278-3649","issn":["0278-3649","1741-3176"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Robotics Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037867082","display_name":"Kimberly Noonan","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Noonan","raw_affiliation_strings":["University of North Carolina, Chapel Hill, NC 27599, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina, Chapel Hill, NC 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010683408","display_name":"D. P. O\u2019Brien","orcid":"https://orcid.org/0000-0002-9262-5168"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David O'Brien","raw_affiliation_strings":["University of North Carolina, Chapel Hill, NC 27599, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina, Chapel Hill, NC 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074061303","display_name":"Jack Snoeyink","orcid":"https://orcid.org/0000-0002-3887-4008"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jack Snoeyink","raw_affiliation_strings":["University of North Carolina, Chapel Hill, NC 27599, USA,","University of North Carolina, Chapel Hill, NC, 27599, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina, Chapel Hill, NC 27599, USA,","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"University of North Carolina, Chapel Hill, NC, 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074061303"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":null,"apc_paid":null,"fwci":0.7582,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.69116609,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"24","issue":"11","first_page":"971","last_page":"982"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9769999980926514,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10571","display_name":"Robotic Mechanisms and Dynamics","score":0.9373000264167786,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ramachandran-plot","display_name":"Ramachandran plot","score":0.8164910078048706},{"id":"https://openalex.org/keywords/inverse-kinematics","display_name":"Inverse kinematics","score":0.7527002096176147},{"id":"https://openalex.org/keywords/kinematics","display_name":"Kinematics","score":0.7524595856666565},{"id":"https://openalex.org/keywords/motion","display_name":"Motion (physics)","score":0.6772416234016418},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5335092544555664},{"id":"https://openalex.org/keywords/ideal","display_name":"Ideal (ethics)","score":0.5163256525993347},{"id":"https://openalex.org/keywords/inverse","display_name":"Inverse","score":0.5089855194091797},{"id":"https://openalex.org/keywords/work","display_name":"Work (physics)","score":0.4103374183177948},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4088669419288635},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.3485490083694458},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.28520143032073975},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.27724170684814453},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.22644534707069397},{"id":"https://openalex.org/keywords/classical-mechanics","display_name":"Classical mechanics","score":0.21351277828216553},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.19727271795272827},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.18949094414710999},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.09216254949569702},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.08891308307647705}],"concepts":[{"id":"https://openalex.org/C14301744","wikidata":"https://www.wikidata.org/wiki/Q579211","display_name":"Ramachandran plot","level":3,"score":0.8164910078048706},{"id":"https://openalex.org/C17816587","wikidata":"https://www.wikidata.org/wiki/Q1501872","display_name":"Inverse kinematics","level":3,"score":0.7527002096176147},{"id":"https://openalex.org/C39920418","wikidata":"https://www.wikidata.org/wiki/Q11476","display_name":"Kinematics","level":2,"score":0.7524595856666565},{"id":"https://openalex.org/C104114177","wikidata":"https://www.wikidata.org/wiki/Q79782","display_name":"Motion (physics)","level":2,"score":0.6772416234016418},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5335092544555664},{"id":"https://openalex.org/C2776639384","wikidata":"https://www.wikidata.org/wiki/Q840396","display_name":"Ideal (ethics)","level":2,"score":0.5163256525993347},{"id":"https://openalex.org/C207467116","wikidata":"https://www.wikidata.org/wiki/Q4385666","display_name":"Inverse","level":2,"score":0.5089855194091797},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.4103374183177948},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4088669419288635},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3485490083694458},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.28520143032073975},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.27724170684814453},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.22644534707069397},{"id":"https://openalex.org/C74650414","wikidata":"https://www.wikidata.org/wiki/Q11397","display_name":"Classical mechanics","level":1,"score":0.21351277828216553},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.19727271795272827},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18949094414710999},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.09216254949569702},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.08891308307647705},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1177/0278364905059108","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0278364905059108","pdf_url":null,"source":{"id":"https://openalex.org/S73484101","display_name":"The International Journal of Robotics Research","issn_l":"0278-3649","issn":["0278-3649","1741-3176"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Robotics Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W85390549","https://openalex.org/W1491063910","https://openalex.org/W1492098934","https://openalex.org/W1521042556","https://openalex.org/W1541953941","https://openalex.org/W1570420806","https://openalex.org/W1585607520","https://openalex.org/W1864844681","https://openalex.org/W1869418976","https://openalex.org/W1965205049","https://openalex.org/W1975210424","https://openalex.org/W1987454179","https://openalex.org/W1987836768","https://openalex.org/W2018562664","https://openalex.org/W2019476648","https://openalex.org/W2030148200","https://openalex.org/W2054154028","https://openalex.org/W2062775485","https://openalex.org/W2067484689","https://openalex.org/W2074986801","https://openalex.org/W2094178674","https://openalex.org/W2107039563","https://openalex.org/W2116275717","https://openalex.org/W2129153475","https://openalex.org/W2134216529","https://openalex.org/W2135085018","https://openalex.org/W2137604324","https://openalex.org/W2138817605","https://openalex.org/W2149186423","https://openalex.org/W2166485929","https://openalex.org/W2219883856","https://openalex.org/W2397877732","https://openalex.org/W3099514962","https://openalex.org/W4298231803"],"related_works":["https://openalex.org/W2084494155","https://openalex.org/W2119963650","https://openalex.org/W2972304526","https://openalex.org/W2367567586","https://openalex.org/W2380210784","https://openalex.org/W2770397302","https://openalex.org/W998473388","https://openalex.org/W2375415610","https://openalex.org/W4235013387","https://openalex.org/W2898458249"],"abstract_inverted_index":{"To":[0],"investigate":[1],"the":[2,5,44,81],"parameters":[3],"of":[4,31,43,54,83],"protein":[6,32],"design":[7],"problem":[8],"that":[9,22],"we":[10,17,60,69],"are":[11,61],"exploring":[12],"in":[13,40,56],"collaboration":[14],"with":[15,71],"biochemists,":[16],"have":[18],"developed":[19],"a":[20],"tool":[21],"uses":[23],"inverse":[24],"kinematics":[25],"to":[26,38,58,63,79],"support":[27],"moving":[28],"small":[29],"fragments":[30],"backbone,":[33],"while":[34],"respecting":[35],"biochemists'":[36],"desires":[37,67],"\u201cremain":[39],"favorable":[41],"regions":[42],"Ramachandran":[45],"plot\u201d":[46],"and":[47],"\u201cpreserve":[48],"ideal":[49],"geometry\u201d.":[50],"By":[51],"presenting":[52],"estimates":[53],"derivatives":[55],"response":[57],"motion,":[59],"able":[62],"refine":[64],"these":[65],"qualitative":[66],"as":[68],"work":[70],"our":[72],"collaborators.":[73],"We":[74],"then":[75],"explore":[76],"low-dimensional":[77],"bases":[78],"parametrize":[80],"space":[82],"backbone":[84],"motions.":[85]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-05-03T06:03:33.228499","created_date":"2025-10-10T00:00:00"}