{"id":"https://openalex.org/W1986677428","doi":"https://doi.org/10.1162/neco.2008.07-06-292","title":"Phase Precession Through Synaptic Facilitation","display_name":"Phase Precession Through Synaptic Facilitation","publication_year":2007,"publication_date":"2007-12-17","ids":{"openalex":"https://openalex.org/W1986677428","doi":"https://doi.org/10.1162/neco.2008.07-06-292","mag":"1986677428","pmid":"https://pubmed.ncbi.nlm.nih.gov/18085985"},"language":"en","primary_location":{"id":"doi:10.1162/neco.2008.07-06-292","is_oa":false,"landing_page_url":"https://doi.org/10.1162/neco.2008.07-06-292","pdf_url":null,"source":{"id":"https://openalex.org/S207023548","display_name":"Neural Computation","issn_l":"0899-7667","issn":["0899-7667","1530-888X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083707266","display_name":"Kay Thurley","orcid":"https://orcid.org/0000-0003-4857-1083"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Kay Thurley","raw_affiliation_strings":["Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013263880","display_name":"Christian Leibold","orcid":"https://orcid.org/0000-0002-4859-8000"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Christian Leibold","raw_affiliation_strings":["Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany; Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany; Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049476782","display_name":"Anja Gundlfinger","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Anja Gundlfinger","raw_affiliation_strings":["Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090979518","display_name":"Dietmar Schmitz","orcid":"https://orcid.org/0000-0003-2741-5241"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dietmar Schmitz","raw_affiliation_strings":["Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014357341","display_name":"Richard Kempter","orcid":"https://orcid.org/0000-0002-5344-2983"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Richard Kempter","raw_affiliation_strings":["Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany; Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Theoretical Biology, Department of Biology, Humboldt-Universit\u00e4t zu Berlin, 10115 Berlin, Germany; Neuroscience Research Center, Charit\u00e9, Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany; and Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5013263880","https://openalex.org/A5014357341","https://openalex.org/A5049476782","https://openalex.org/A5083707266","https://openalex.org/A5090979518"],"corresponding_institution_ids":["https://openalex.org/I39343248"],"apc_list":null,"apc_paid":null,"fwci":0.705,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.6768981,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"20","issue":"5","first_page":"1285","last_page":"1324"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/precession","display_name":"Precession","score":0.8154566287994385},{"id":"https://openalex.org/keywords/bursting","display_name":"Bursting","score":0.6679271459579468},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.6440935134887695},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5525527000427246},{"id":"https://openalex.org/keywords/phase","display_name":"Phase (matter)","score":0.4847840666770935},{"id":"https://openalex.org/keywords/hippocampus","display_name":"Hippocampus","score":0.45841145515441895},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.25396689772605896},{"id":"https://openalex.org/keywords/quantum-mechanics","display_name":"Quantum mechanics","score":0.17336690425872803}],"concepts":[{"id":"https://openalex.org/C81502235","wikidata":"https://www.wikidata.org/wiki/Q104225","display_name":"Precession","level":2,"score":0.8154566287994385},{"id":"https://openalex.org/C195221683","wikidata":"https://www.wikidata.org/wiki/Q5000649","display_name":"Bursting","level":2,"score":0.6679271459579468},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.6440935134887695},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5525527000427246},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.4847840666770935},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.45841145515441895},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.25396689772605896},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.17336690425872803}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1162/neco.2008.07-06-292","is_oa":false,"landing_page_url":"https://doi.org/10.1162/neco.2008.07-06-292","pdf_url":null,"source":{"id":"https://openalex.org/S207023548","display_name":"Neural Computation","issn_l":"0899-7667","issn":["0899-7667","1530-888X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315718","host_organization_name":"The MIT Press","host_organization_lineage":["https://openalex.org/P4310315718"],"host_organization_lineage_names":["The MIT Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computation","raw_type":"journal-article"},{"id":"pmid:18085985","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18085985","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural computation","raw_type":null},{"id":"pmh:oai:edoc.mdc-berlin.de:13452","is_oa":false,"landing_page_url":"http://edoc.mdc-berlin.de/13452/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400224","display_name":"MDC Repository (Max-Delbrueck-Center for Molecular Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:epub.ub.uni-muenchen.de:14752","is_oa":false,"landing_page_url":"https://epub.ub.uni-muenchen.de/14752/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401845","display_name":"Open access LMU (Ludwid Maxmilian's Universitat Munchen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I8204097","host_organization_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","host_organization_lineage":["https://openalex.org/I8204097"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Neural Computation","raw_type":"doc-type:article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W1248629789","https://openalex.org/W1809325656","https://openalex.org/W1840439775","https://openalex.org/W1898271064","https://openalex.org/W1908283583","https://openalex.org/W1931805140","https://openalex.org/W1967963204","https://openalex.org/W1974719406","https://openalex.org/W1975070097","https://openalex.org/W1979323638","https://openalex.org/W1983505832","https://openalex.org/W1983560663","https://openalex.org/W1983628429","https://openalex.org/W1985333845","https://openalex.org/W1989272970","https://openalex.org/W1989932452","https://openalex.org/W1991417588","https://openalex.org/W1992388076","https://openalex.org/W2001186755","https://openalex.org/W2004974848","https://openalex.org/W2007926106","https://openalex.org/W2008936540","https://openalex.org/W2012479488","https://openalex.org/W2016106846","https://openalex.org/W2016633654","https://openalex.org/W2022995207","https://openalex.org/W2024529445","https://openalex.org/W2028160379","https://openalex.org/W2031543773","https://openalex.org/W2032438999","https://openalex.org/W2050080293","https://openalex.org/W2052515926","https://openalex.org/W2053848346","https://openalex.org/W2055715294","https://openalex.org/W2055775269","https://openalex.org/W2056336718","https://openalex.org/W2063067007","https://openalex.org/W2064825919","https://openalex.org/W2071344447","https://openalex.org/W2073055671","https://openalex.org/W2074690946","https://openalex.org/W2081412504","https://openalex.org/W2081957056","https://openalex.org/W2088382964","https://openalex.org/W2089316513","https://openalex.org/W2090584164","https://openalex.org/W2091697313","https://openalex.org/W2091999943","https://openalex.org/W2093362207","https://openalex.org/W2096916130","https://openalex.org/W2099512174","https://openalex.org/W2100058016","https://openalex.org/W2102172922","https://openalex.org/W2103179919","https://openalex.org/W2103786980","https://openalex.org/W2107834681","https://openalex.org/W2110949403","https://openalex.org/W2112902525","https://openalex.org/W2119565218","https://openalex.org/W2122865736","https://openalex.org/W2124292936","https://openalex.org/W2125181231","https://openalex.org/W2128595101","https://openalex.org/W2132629172","https://openalex.org/W2135191781","https://openalex.org/W2139203983","https://openalex.org/W2141088859","https://openalex.org/W2144668425","https://openalex.org/W2150357694","https://openalex.org/W2151108396","https://openalex.org/W2154034179","https://openalex.org/W2165884913","https://openalex.org/W2171137389","https://openalex.org/W2171795623","https://openalex.org/W2410446460","https://openalex.org/W2478045881","https://openalex.org/W2914478155","https://openalex.org/W3021526609","https://openalex.org/W4240516459","https://openalex.org/W4247763225"],"related_works":["https://openalex.org/W2080788537","https://openalex.org/W3181055709","https://openalex.org/W2002830460","https://openalex.org/W2064213689","https://openalex.org/W2036451364","https://openalex.org/W3195397619","https://openalex.org/W4243975172","https://openalex.org/W2130293530","https://openalex.org/W2165689100","https://openalex.org/W2090649048"],"abstract_inverted_index":{"Phase":[0],"precession":[1,45,80,152,204],"is":[2,7],"a":[3,20,41,44,105],"relational":[4],"code":[5],"that":[6,95,177],"thought":[8],"to":[9,51,109],"be":[10],"important":[11],"for":[12,15,202],"episodic-like":[13],"memory,":[14],"instance,":[16],"the":[17,25,58,76,126,133,144,148,161,167,171,178,182,206,210],"learning":[18],"of":[19,22,33,46,61,78,104,120,129,150,163,181,209],"sequence":[21],"places.":[23],"In":[24,84],"hippocampus,":[26],"places":[27],"are":[28,200],"encoded":[29],"through":[30,89],"bursting":[31],"activity":[32],"so-called":[34],"place":[35,172],"cells.":[36],"The":[37,73,174],"spikes":[38],"in":[39,64,98,205],"such":[40,123,187],"burst":[42],"exhibit":[43],"their":[47],"firing":[48],"phases":[49,142],"relative":[50],"field":[52],"potential":[53,102],"theta":[54,59,66,157],"oscillations":[55,103],"(4-12":[56],"Hz);":[57],"phase":[60,79,110,121,151,164,203],"action":[62],"potentials":[63],"successive":[65],"cycles":[67],"progressively":[68],"decreases":[69],"toward":[70],"earlier":[71],"phases.":[72],"mechanisms":[74],"underlying":[75],"generation":[77],"are,":[81],"however,":[82],"unknown.":[83],"this":[85],"letter,":[86],"we":[87],"show":[88],"mathematical":[90],"analysis":[91],"and":[92,135,143,159,193,196],"numerical":[93],"simulations":[94],"synaptic":[96],"facilitation":[97],"combination":[99],"with":[100],"membrane":[101],"neuron":[106],"gives":[107],"rise":[108],"precession.":[111],"This":[112],"biologically":[113],"plausible":[114],"model":[115,175],"reproduces":[116],"experimentally":[117],"observed":[118],"features":[119,180],"precession,":[122],"as":[124,188],"(1)":[125],"progressive":[127],"decrease":[128],"spike":[130,141],"phases,":[131],"(2)":[132],"nonlinear":[134],"often":[136],"also":[137],"bimodal":[138],"relation":[139],"between":[140],"animal's":[145,168],"place,":[146],"(3)":[147],"range":[149],"being":[153],"smaller":[154],"than":[155],"one":[156],"cycle,":[158],"(4)":[160],"dependence":[162],"jitter":[165],"on":[166],"location":[169],"within":[170],"field.":[173],"suggests":[176],"peculiar":[179],"hippocampal":[183],"mossy":[184],"fiber":[185],"synapse,":[186],"its":[189,197],"large":[190],"efficacy,":[191],"long-lasting":[192],"strong":[194],"facilitation,":[195],"phase-locked":[198],"activation,":[199],"essential":[201],"CA3":[207],"region":[208],"hippocampus.":[211]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}